Neonatal DSP-4 treatment impairs 5-HT1B receptor reactivity in adult rats. behavioral and biochemical studies

Pharmacological Reports

Volumn 62, Issue 4, 2010, Pages 608-620

  Ferdyn Drosik, Marzena ^a   Nowak, Przemysław ^a   Bojanek, Kamila ^a   Bałasz, Michał ^a   Kasperski, Jacek ^a   Skaba, Dariusz ^a   Muchacki, Rafał ^a   Kostrzewa, Richard M ^b  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

^b East Tennessee State University   (United States)

Author keywords

Anxiety; DSP 4; Lesion; Rats

Indexed keywords

2 BROMO N (2 CHLOROETHYL) N ETHYLBENZYLAMINE; 5 PROPOXY 3 (1,2,5,6 TETRAHYDRO 4 PYRIDYL)PYRROLO[3,2 B]PYRIDINE; AUTORECEPTOR; FENCLONINE; N [3 [3 (DIMETHYLAMINO)ETHOXY] 4 METHOXYPHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)(1,1' BIPHENYL) 4 CARBOXAMIDE HYDROCHLORIDE; NEUROTOXIN; SB 216641; SEROTONIN 1B ANTAGONIST; SEROTONIN 1B RECEPTOR; UNCLASSIFIED DRUG;

ADULT ANIMAL; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; DRUG MECHANISM; MALE; MAZE TEST; MICRODIALYSIS; NERVE ENDING; NERVE LESION; NEUROTOXICITY; NEWBORN; NEWBORN PERIOD; NONHUMAN; NORADRENERGIC NERVE; NORADRENERGIC SYSTEM; PREFRONTAL CORTEX; PRESYNAPTIC NERVE; RAT; RECEPTOR DOWN REGULATION; SEROTONIN RELEASE; SEROTONINERGIC SYSTEM; SEROTONINERGIC TRANSMISSION;

EID: 77957994859     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/S1734-1140(10)70318-2     Document Type: Article

References (63)

1. 1B receptors in the regulation of serotonin cell firing and release in the rat brain. J Neurochem, 2001, 79, 172-182.
2. 1B mRNA in rat dorsal raphe nucleus reverses rapidly after drug discontinuation. J Neurosci Res, 2000, 61, 82-87.
3. Arborelius L, Linnér L, Wallsten C, Ahlenius S, Svensson TH: Partial 5-HT1A receptor agonist properties of (-)pindolol in combination with citalopram on serotonergic dorsal raphe cell firing in vivo. Psychopharmacology (Berl), 2000, 151, 77-84.
4. Blows WT: Neurotransmitters of the brain: serotonin, noradrenaline (norepinephrine), and dopamine. J Neurosci Nurs, 2000, 32, 234-238.
5. Bortel A, Nowak P, Brus R: Neonatal DSP-4 treatment modifies GABA-ergic neurotransmission in the prefrontal cortex of adult rats. Neurotox Res, 2008, 13, 247-252.
6. Bortel A, Słomian L, Nitka D, Świerszcz M, Jaksz M, Adamus-Sitkiewicz B, Nowak P et al.: Neonatal N-(-2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) treatment modifies the vulnerability to phenobarbitaland ethanol-evoked sedative-hypnotic effects in adult rats. Pharmacol Rep, 2008, 60, 331-338.
7. Bortolozzi A, Amargós-Bosch M, Toth M, Artigas F, Adell A: In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT1A receptor knockout mice. J Neurochem, 2004, 88, 1373-1379.
8. Briley M, Moret C: Neurobiological mechanisms involved in antidepressant therapies. Clin Neuropharmacol, 1993, 16, 387-400.
9. Carlsson A, Davis JN, Kher W, Lindqvist M, Atack CV: Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in vivo using an inhibitor of the aromatic amino acid decarboxylase. Naunyn Schmiedebergs Arch Pharmacol, 1972, 275, 153-168.
10. Cassano T, Gaetani S, Morgese MG, Macheda T, Laconca L, Dipasquale P, Taltavull J et al.: Monoaminergic changes in locus coeruleus and dorsal raphe nucleus following noradrenaline depletion. Neurochem Res, 2009, 34, 1417-1126.
11. 1B receptor ligands in rats: a possible mechanism of action. J Pharm Pharmacol, 2005, 57, 253-257.
12. 1B receptor in dorsal raphe nucleus using Herpes Simplex Virus gene transfer increases anxiety behavior after inescapable stress. J Neurosci, 2002, 22, 4550-4562.
13. 2A/2C binding sites in adult rat basal ganglia following lesions of serotonergic neurons. Brain Res, 1998, 793, 103-111.
14. Couto LB, Moroni CR, dos Reis Ferreira CM, Elias-Filho DH, Parada CA, Pelá IR, Coimbra NC: Descriptive and functional neuroanatomy of locus coeruleusnoradrenaline-containing neurons involvement in bradykinin-induced antinociception on principal sensory trigeminal nucleus. J Chem Neuroanat, 2006, 32, 28-45.
15. Dabrowska J, Nowak P, Brus R: Desensitization of 5-HT1A autoreceptors induced by neonatal DSP-4 treatment. Eur Neuropsychopharmacol, 2007, 17, 129-137.
16. Dabrowska J, Nowak P, Brus R: Reactivity of 5-HT1A receptor in adult rats after neonatal noradrenergic neurons' lesion - Implications for antidepressant-like action. Brain Res, 2008, 1239, 66-76.
17. 1B autoreceptors: a microdialysis study in knockout mice. Psychopharmacology (Berl), 2002, 162, 419-424.
18. 1B receptor knockout mice. Eur J Pharmacol, 2002, 439, 93-100.
19. 1B and GABAA receptors. Psychopharmacology (Berl), 2000, 149, 277-285.
20. Fontana DJ, McMiller LV, Commissaris RL: Depletion of brain norepinephrine: differential influence on anxiolyic treatment effects. Psychopharmacology (Berl), 1999, 143, 197-208.
21. Guiard BP, El Mansari M, Merali Z, Blier P: Functional interactions between dopamine, serotonin and norepinephrine neurons: an in-vivo electrophysiological study in rats with monoaminergic lesions. Int J Neuropsychopharmacol, 2008, 11, 625-639.
22. Haddjeri N, Blier P, de Montigny C: Noradrenergic modulation of central serotonergic neurotransmission: acute and long-term actions of mirtazapine. Int Clin Psychopharmacol, 1995, 10, Suppl 4, 11-17.
23. Haddjeri N, Lavoie N, Blier P: Electrophysiological evidence for the tonic activation of 5-HT1A autoreceptors in the rat dorsal raphe nucleus. Neuropsychopharmacology, 2004, 29, 1800-1806.
24. Harro J, Pähkla R, Modiri A-R, Harro M, Kask A, Oreland L: Dose-dependent effects of noradrenergic denervation by DSP-4 treatment on forced swimming and β-adrenoceptor binding in the rat. J Neural Transm, 1999, 106, 619-629.
25. Hughes ZA, Dawson LA: Differential autoreceptor control of extracellular 5-HT in guinea pig and rat: species and regional differences. Psychopharmacology (Berl), 2004, 172, 87-93.
26. Jongsma ME, Bosker FJ, Cremers TI, Westerink BH, den Boer JA: The effect of chronic selective serotonin reuptake inhibitor treatment on serotonin 1B receptor sensitivity and HPA axis activity. Prog Neuropsychopharmacol Biol Psychiatry, 2005, 29, 738-744.
27. Jonsson G, Hallman H: Response of central monoamine neurons following an early neurotoxic lesion. Bibl Anat, 1982, 23, 76-92.
28. 1B receptors. J Pharmacol Exp Ther, 2000, 292, 1111-1117.
29. Kostowski W, Danysz W, Płaźnik A, Nowakowska E: Studies on the locus coeruleus system in an animal model for antidepressive activity. Pol J Pharmacol Pharm, 1984, 36, 523-530.
30. Kostrzewa RM: Reorganization of noradrenergic neuronal systems following neonatal chemical and surgical injury. Prog Brain Res, 1988, 73, 405-423.
31. Kulkarni VA, Jha S, Vaidya VA: Depletion of norepinephrine decreases the proliferation, but does not influence the survival and differentiation, of granule cell progenitors in the adult rat hippocampus. Eur J Neurosci, 2002, 16, 2008-2012.
32. 1B, and 5-HT3 receptors in the rat spinal cord. J Neural Transm Gen Sect, 1995, 100, 207-223.
33. 1B autoreceptor activity in rat brain: regional differences. J Neurosci Methods, 2004, 140, 133-139.
34. Lin D, Parsons LH: Anxiogenic-like effect of serotonin1B receptor stimulation in the rat elevated plusmaze. Pharmacol Biochem Behav, 2002, 71, 581-587.
35. Loughlin SE, Foote SL, Bloom FE: Efferent projections of nucleus locus coeruleus: topographic organization of cells of origin demonstrated by three-dimensional reconstruction. Neuroscience, 1986, 18, 291-306.
36. Magnusson O, Nilsson LB, Westerlund A: Simultaneous determination of dopamine, DOPAC and homovanillic acid. Direct injection of supernatants from brain tissue homogenates in a liquid chromatography-electrochemical detection system. J Chromatogr, 1980, 221, 237-247.
37. 1B binding sites following 5,7-dihydroxytryptamine axotomy in the adult rat. Brain Res, 1993, 623, 345-348.
38. Millan MJ: The neurobiology and control of anxious states. Prog Neurobiol, 2003, 70, 83-244.
39. 2-adrenoceptors: II. Influence on monoaminergic transmission, motor function, and anxiety in comparison with dexmedetomidine and clonidine. J Pharmacol Exp Ther, 2000, 295, 1206-1222.
40. 1B mRNA regulation in two animal models of altered stress reactivity. Biol Psychiatry, 2002, 51, 902-908.
41. 1B autoreceptors: regional differences and effects of WAY-100635. Eur J Pharmacol, 2004, 486, 25-30.
42. Noda M, Higashida H, Aoki S, Wada K: Multiple signal transduction pathways mediated by 5-HT receptors. Mol Neurobiol, 2004, 29, 31-39.
43. Nowak P, Bortel A, Dabrowska J, Biedka I, Słomian G, Roczniak W, Kostrzewa RM, Brus R: Amphetamine and mCPP effects on dopamine and serotonin striatal in vivo microdialysates in an animal model of hyperactivity. Neurotox Res, 2007, 11, 131-144.
44. Nowak P, Jochem J, Zwirska-Korczala K, Josko J, Noras L, Kostrzewa RM, Brus R: Ontogenetic noradrenergic lesion alters histaminergic activity in adult rats. Neurotox Res, 2008, 13, 79-83.
45. Nowak P, Labus Ł, Kostrzewa RM, Brus R: DSP-4 prevents dopamine receptor priming by quinpirole. Pharmacol Biochem Behav, 2006, 84, 3-7.
46. Pellow S, Chopin P, File SE, Briley M: Validation of open: closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods, 1985, 14, 149-167.
47. Petty F, Kramer G, Wilson L: Prevention of learned helplessness: in vivo correlation with cortical serotonin. Pharmacol Biochem Behav, 1992, 43, 361-367.
48. Pompeiano M, Palacios JM, Mengod G: Distribution and cellular localization of mRNA coding for 5-HT1A receptor in the rat brain: correlation with receptor binding. J Neurosci, 1992, 12, 440-453.
49. Pudovkina OL, Cremers TI, Westerink BH: The interaction between the locus coeruleus and dorsal raphe nucleus studied with dual-probe microdialysis. Eur J Pharmacol, 2002, 445, 37-42.
50. 1A antagonists in guinea pigs. Pharmacol Biochem Behav, 2008, 88, 196-204.
51. Saito H, Matsumoto M, Togashi H, Yoshioka M: Functional interaction between serotonin and other neuronal systems: focus on in vivo microdialysis studies. Jpn J Pharmacol, 1996, 70, 203-205.
52. Sanders JD, Happe HK, Bylund DB, Murrin LC: Differential effects of neonatal norepinephrine lesions on immediate early gene expression in developing and adult rat brain. Neuroscience, 2008, 157, 821-832.
53. Sari Y, Miquel MC, Brisorgueil MJ, Ruiz G, Doucet E, Hamon M, Vergé D.: Cellular and subcellular localization of 5-hydroxytryptamine1B receptors in the rat central nervous system: immunocytochemical, autoradiographic and lesion studies. Neuroscience, 1999, 88, 899-915.
54. 1B autoreceptor function in the anterior hypothalamus in vivo: effect of chronic antidepressant drug treatment. Br J Pharmacol, 1999, 126, 1777-1784.
55. Sieber-Blum M, Ren Z: Norepinephrine transporter expression and function in noradrenergic cell differentiation. Mol Cell Biochem, 2000, 212, 61-70.
56. Svensson TH, Bunney BS, Aghajanian GK: Inhibition of both noradrenergic and serotonergic neurons in brain by the α-adrenergic agonist clonidine. Brain Res, 1975, 92, 291-306.
57. 2A receptor antagonism on the firing activity of norepinephrine neurons. J Pharmacol Exp Ther, 2002, 302, 983-991.
58. A receptors: a microiontophoretic study in the rat locus coeruleus. Synapse, 2001, 42, 203-212.
59. Vandermaelen CP, Aghajanian GK: Electrophysiological and pharmacological characterization of serotonergic dorsal raphe neurons recorded extracellularly and intracellularly in rat brain slices. Brain Res, 1983, 289, 109-119.
60. Waterhouse BD, Border B, Wahl L, Mihailoff GA: Topographic organization of rat locus coeruleus and dorsal raphe nuclei: distribution of cells projecting to visual system structures. J Comp Neurol, 1993, 336, 345-361.
61. 1A/B receptor antagonist and serotonin reuptake inhibitor SB-649915: preclinical evidence for hastened onset of antidepressant/anxiolytic efficacy. CNS Drug Rev, 2007, 13, 206-223.
62. 1B receptors within the ventral tegmental area in regulation of mesolimbic dopaminergic neuronal activity via GABA mechanisms: a study with dual-probe microdialysis. Brain Res, 2004, 1021, 82-91
63. Zhang JM, Dix J, Langtimm-Sedlak CJ, Trusk T, Schroeder B, Hoffmann R, Strosberg AD et al.: Neurotrophin-3-and norepinephrine-mediated adrenergic differentiation and the inhibitory action of desipramine and cocaine. J Neurobiol, 1997, 32, 262-280.