Abrogation of wild-type p53 mediated growth-inhibition by nuclear exclusion

Oncogene

Volumn 12, Issue 8, 1996, Pages 1755-1765

  Knippschild, Uwe ^a   Oren, Moshe ^b   Deppert, Wolfgang ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Nuclear cytoplasmic transport; Tumor suppressor p53

Indexed keywords

PROTEIN P53;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELL STRAIN; CELL TRANSFORMATION; CONTROLLED STUDY; CYTOPLASM; EMBRYO; FIBROBLAST; NONHUMAN; ONCOGENE H RAS; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; TEMPERATURE SENSITIVE MUTANT; TRANSACTIVATION; TUMOR SUPPRESSOR GENE;

ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; BASE SEQUENCE; CELL DIVISION; CELL LINE, TRANSFORMED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; CYCLOHEXIMIDE; CYTOPLASM; EMETINE; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; GENES, RAS; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PROTEINS; PHEOCHROMOCYTOMA; PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITORS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; RATS; TEMPERATURE; TRANSFECTION; TRANSFORMATION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 0029919728     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (78)

1. Barak Y and Oren M. (1992). EMBO J., 11, 2115-2121.
2. Barak Y, Juven T, Haffner R and Oren M. (1993). EMBO J., 12, 461-468.
3. Barak Y, Gottlieb E, Juven-Gershon T and Oren M. (1994). Genes and Dev., 8, 1739-1749.
4. Bischoff JR, Friedman PN, Marshak DR, Prives C and Beach D. (1990). Proc. Natl. Acad. Sci. USA, 87, 4766-4770.
5. Cahilly-Snyder L, Yang-Feng T, Francke U and George DL. (1987). Somat. Cell. Mol. Genet., 13, 235-244.
6. Caron de Fromentel C and Soussi T. (1992). Genes, chromosomes and cancer, 4, 1-15.
7. Chang F, Syrjanen S, Kurvinen K and Syrjanen K. (1993). Am. J. Gastroenterol., 88, 174-188.
8. Ciechanover A, Shkedy D, Oren M and Bercovich B. (1994). J. Cell. Biochem., 269, 9582-9589.
9. Cox LS and Lane DP. (1995). BioEssays, 17, 501-508.
10. Deppert W. (1993). Molecular and Cell Biological Methods in the Diagnosis of Malignant Diseases, Wagener C and Neumann S (eds.), Springer-Verlag Berlin Heidelberg, pp. 27-39.
11. Deppert W. (1994). Cancer Biol., 5, 187-202.
12. Donehower LA and Bradley A. (1993). Biochim. Biophys. Acta Rev. Cancer, 1155, 181-205.
13. Dulic V, Kaufmann WK, Wilson SJ, Tlsty TD, Lees E, Harper JW, Elledge SJ and Reed SI. (1994). Cell, 76, 1013-1023.
14. El-Deiry WS, Kenn SE, Pietenpol JA, Kinzler KW et al. (1992). Nature Gen, 1, 45-49.
15. El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW and Vogelstein B. (1993). Cell, 75, 817-825.
16. El-Deiry WS, Harper JW, O'Connor PM, Velculescu VE, Canman CE, Jackman J, Pietenpol JA, Bunrell M, Hill DE, Wang Y, Wiman KG, Mercer WE, Kastan MB, Kohn KW, Elledge SJ, Kinzler KW and Vogelstein B. (1994). Cancer Res., 54, 1169-1174.
17. Elkind NB, Goldfinger N and Rotter V (1995). Oncogene, 11, 841-851.
18. Fakharzadeh SS, Tnusko SP and George DL. (1991). EMBO J., 19, 1565-1569.
19. Finlay CA. (1993). Mol. Cell. Biol., 13, 301-306.
20. Florenes VA, Mælandsmo GM, Forus A, Andreassen Å and Myklebost O. (1994). JNCI, 86, 1297-1302.
21. Flores-Rozas H, Kelman Z, Dean FB, Pan Z-Q, Harper JW, Elledge SJ, O'Donnell M and Hurvitz J. (1994). Proc. Natl. Acad. Sci. USA, 91, 8655-8659.
22. Forus A, Florenes VA, Maelandsmo GM, Meltzer PS, Fodstad O and Myklebost O. (1993). Cell Growth Differ, 4, 1065-1070.
23. Fukusawa K, Sakoulas G, Pollack RE and Chen S. (1991). Mol. Cell. Biol., 11, 3472-3483.
24. Gannon JV and Lane DP. (1991). Nature, 349, 802-806.
25. Ginsberg D, Michael-Michalovitz D, Ginsberg D and Oren M. (1991). Mol. Cell. Biol., 11, 582-585.
26. Gorman C, Merlino T, Willingham M, Pastan I et al. (1982). Proc. Natl. Acad. Sci. USA, 79, 6777-6781.
27. Haffner R and Oren M. (1995). Curr. Op. Genet. Dev., 5, 84-90.
28. Harlow E, Crawford LV, Pim DC and Williamson NM. (1981). J. Virol., 39, 861-869.
29. Harper JW, Adami GR, Wei N, Keyomarsi K and Elledge SJ. (1993). Cell, 75, 805-816.
30. Juven T, Barak Y, Zauberman A, George DL and Oren M. (1993). Oncogene, 8, 3411-3416.
31. Kalderon D, Richardson WD, Markham AF and Smith AE. (1984). Nature, 311, 33-38.
32. Kalthoff H, Schmiegel W, Roeder C, Kasche D et al. (1993). Oncogene, 8, 289-298.
33. Kern SE, Pietenpol JA, Thiagalingam S, Seymour A et al (1992). Science, 256, 827-830.
34. Knippschild U, Kolzau T and Deppert W. (1995). Oncogene, 11, 683-690.
35. Ladanyi M, Cha C, Lewis R, Ghanwar SC, Huvos AG and Healey JM. (1993). Cancer Res., 53, 16-18.
36. Laimins LA. (1993). Infect. Agens. Dis., 2, 74-86.
37. Landers JE, Haines DS, Strauss III JF and George DL. (1994). Oncogene, 9, 2745-2750.
38. Lane DP. (1992a). Nature, 358, 15-16.
39. Lane DP. (1992b). Nature, 359, 486-487.
40. Lane DP. (1993). Nature, 362, 786-787.
41. Lanford RE and Butel JS. (1982). Virology, 119, 169-184.
42. Lanford RE and Butel JS. (1984). Cell, 37, 801-813.
43. Lanford RE and Butel JS. (1985). Virology, 147, 72-80.
44. Levine AJ, Chang A, Dittmer D, Notterman DA, Silver A, Thorn K, Welsh D and Wu M. (1994). J. Lab. Clin. Med., 123, 817-823.
45. Levine AJ, Momand J and Finlay CA. (1991). Nature, 351, 453-456.
46. Lowe SW, Bodis S, McClatchey A, Remington L et al. (1994). Science, 266, 807-810.
47. Martin K, Trouche D, Hagemeier C, Sorensen TS, La Thangue NB and Kouzarides T. (1995). Nature, 375, 691-694.
48. Martinez J, Georgoff I, Martinez J and Levine AJ. (1991). Genes Dev., 5, 151-159.
49. Michalovitz D, Halevy O and Oren M. (1990). Cell, 62, 671-680.
50. Moll UM, Riou G and Levine AJ. (1992). Proc. Natl. Acad. Sci. USA, 89, 7262-7266.
51. Moll UM, LaQuaglia M, Bénard J and Riou G. (1995). Proc. Natl. Acad. Sci. USA, 92, 4407-4411.
52. Mosner J, Mummenbrauer T, Bauer C, Sczakiel G et al. (1995). EMBO J., 14, 4442-4449.
53. Oren M. (1992). FASEB J., 6, 3169-3176.
54. Otto A and Deppert W. (1993). Oncogene, 8, 2591-2603.
55. Patschinsky T and Deppert W. (1990). Oncogene, 5, 1071-1076.
56. Patschinsky T, Knippschild U and Deppert W. (1992). J. Virol., 66, 3846-3859.
57. Perry ME and Levine AJ. (1993). Curr. Op. in Genetics and Dev., 3, 50-54.
58. Picksley SM and Lane DP. (1993). BioEssays, 15, 689-690.
59. Prives C. (1993). Curr. Op. Cell Biol., 5, 214-218.
60. Rihs H-P and Peters R. (1989). EMBO J., 8, 1479-1484.
61. Sambrook J, Fritsch EF and Maniatis T. (1989). Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, 2nd edn.
62. Sanger F, Nickler S and Coulson AR. (1977). Proc. Natl. Acad. Sci. USA, 74, 5463-5467.
63. Scheffner M, Münger K, Byrne JC and Howley PM. (1991). Proc. Natl. Acad. Sci. USA, 88, 5523-5527.
64. Scheffner M, Huibregtse JM and Howley PM. (1994). Proc. Natl. Acad. Sci. USA, 91, 8797-8801.
65. Seiter H and Montenarh M. (1994). Int. J. Biochem., 26, 145-154.
66. Shaulsky G, Goldfinger N, Ben-Ze'ev A and Rotter V. (1990a). Mol. Cell. Biol., 10, 6565-6577.
67. Shaulsky G, Ben-Ze'ev A and Rotter V (1990b). Oncogene, 5, 1707-1711.
68. Soussi T, Legros Y, Lubin R, Ory K and Schlichtholz B. (1994). Int. J. Cancer, 57, 1-9.
69. Staufenbiel M and Deppert W. (1983). Cell, 33, 173-181.
70. Staufenbiel M and Deppert W. (1984). J. Cell Biol., 98, 1886-1894.
71. Stürzbecher H-W, Maimets T, Chumakov P, Brain R, Addison C, Simanis V, Rudge K, Philp R, Grimaldi M, Court W and Jenkins JR. (1990). Oncogene, 5, 795-802.
72. Takahashi K and Suzuki K. (1994). Oncogene, 9, 183-188.
73. Vogelstein B and Kinzler KW. (1992). Cell, 70, 523-526.
74. Waga S, Bauer G and Stillman B. (1994). J. Biol. Chem., 269, 10923-10934.
75. Wu X, Bayle JH, Olson D and Levine AJ. (1993). Genes Dev., 7, 1126-2232.
76. Yewdell JW, Gannon JV and Lane DP. (1986). J. Virol., 59, 444-452.
77. Zambetti GP and Levine AJ. (1993). FASEB J., 7, 855-865.
78. Zerrahn J, Deppert W, Weidemann D, Patschinsky T, Richards F and Milner J. (1992). Oncogene, 7, 1371-1381.