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Volumn 45, Issue 11, 2010, Pages 5120-5129

Synthesis and pharmacological evaluation of clubbed isopropylthiazole derived triazolothiadiazoles, triazolothiadiazines and mannich bases as potential antimicrobial and antitubercular agents

Author keywords

4 Isopropylthiazole; Antitubercular; Cytotoxicity; Mannich bases; Triazolothiadiazines; Triazolothiadiazoles

Indexed keywords

3 (4 ISOPROPYLTHIAZOL 2 YL) 5 THIOXO 1H [1,2,4 TRIAZOL 4 (5H) YL] 4 METHOXYBENZAMIDE; 3 (4 ISOPROPYLTHIAZOL 2 YL) 5 THIOXO 1H [1,2,4 TRIAZOL 4 (5H) YL] 4 METHYLBENZAMIDE; 3 (4 ISOPROPYLTHIAZOL 2 YL) 5 THIOXO 1H [1,2,4 TRIAZOL 4 (5H) YL]BENZAMIDE; 3 (4 ISOPROPYLTHIAZOL 2 YL) 6 (4 METHOXYPHENYL) 7H [1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZINE; 3 (4 ISOPROPYLTHIAZOL 2 YL) 6 (4 NITROPHENYL) 7H [1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZINE; 3 (4 ISOPROPYLTHIAZOL 2 YL) 6 4 TOLYL 7H [1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZINE; 3 (4 ISOPROPYLTHIAZOL 2 YL) 6 METHYL [1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 3 (4 ISOPROPYLTHIAZOL 2 YL) 6 PHENYL 7H [1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZINE; 3 (4 ISOPROPYLTHIAZOL 2 YL) [1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE 6(5H) THIONE; 4 (2 CHLOROBENZYLIDENEAMINO) 5 (4 ISOPROPYLTHIAZOL 2 YL) 2 (MORPHOLINOMETHYL) 2H 1,2,4 TRIAZOLE 3(4H) THIONE; 4 (2 CHLOROBENZYLIDENEAMINO) 5 (4 ISOPROPYLTHIAZOL 2 YL) 2 [(4 METHYLPIPERAZIN 1 YL)METHYL] 2H 1,2,4 TRIAZOLE 3(4H) THIONE; 4 (3,4,5 TRIMETHOXYBENZYLIDENEAMINO) 5 (4 ISOPROPYLTHIAZOL 2 YL) 2 (MORPHOLINOMETHYL) 2H 1,2,4 TRIAZOLE 3(4H) THIONE; 4 (3,4,5 TRIMETHOXYBENZYLIDENEAMINO) 5 (4 ISOPROPYLTHIAZOL 2 YL) 2 [(4 METHYLPIPERAZIN 1 YL)METHYL] 2H 1,2,4 TRIAZOLE 3(4H) THIONE; 4 (4 CHLOROBENZYLIDENEAMINO) 5 (4 ISOPROPYLTHIAZOL 2 YL) 2 (MORPHOLINOMETHYL) 2H 1,2,4 TRIAZOLE 3(4H) THIONE; 4 (4 METHOXYBENZYLIDENEAMINO) 5 (4 ISOPROPYLTHIAZOL 2 YL) 2 [(4 METHYLPIPERAZIN 1 YL)METHYL] 2H 1,2,4 TRIAZOLE 3(4H) THIONE; 4 [3 (4 ISOPROPYLTHIAZOL 2 YL) 7H [1,2,4]TRIAZOLO[3,4 B][1,3,4] THIADIAZINE 6 YL)PHENOL; 4 [4 (DIMETHYLAMINO)BENZYLIDENEAMINO] 5 (4 ISOPROPYLTHIAZOL 2 YL) 2 [(4 METHYLPIPERAZIN 1 YL)METHYL] 2H 1,2,4 TRIAZOLE 3(4H) THIONE; 4 [4 (DIMETHYLAMINO)BENZYLIDENEAMINO] 5 (4 ISOPROPYLTHIAZOL 2 YL) 2 MORPHOLINOMETHYL 2H 1,2,4 TRIAZOLE 3(4H) THIONE; 4 HYDROXY N [3 (4 ISOPROPYLTHIAZOL 2 YL) 5 THIOXO 1H [1,2,4 TRIAZOL 4 (5H) YL]BENZAMIDE; 5 (4 ISOPROPYLTHIAZOL 2 YL) 3 (4 METHYLPIPERAZIN 1 YL) 1,3,4 OXADIAZOLE 2 (3H) THIONE; 5 (4 ISOPROPYLTHIAZOL 2 YL) 3 (MORPHOLINOMETHYL) 1,3,4 OXADIAZOLE 2 (3H) THIONE; 6 (4 BROMOPHENYL) 3 (4 ISOPROPYLTHIAZOL 2 YL) 7H [1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZINE; 6 (4 CHLOROPHENYL) 3 (4 ISOPROPYLTHIAZOL 2 YL) 7H [1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZINE; ANTIINFECTIVE AGENT; CIPROFLOXACIN; ISONIAZID; NORFLOXACIN; THIADIAZOLE DERIVATIVE; THIAZOLE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

EID: 77957844266     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.08.023     Document Type: Article
Times cited : (78)

References (31)
  • 3
    • 0026760182 scopus 로고
    • H.C. Neu Science 257 5073 1992 1064 1072
    • (1992) Science , vol.257 , Issue.5073 , pp. 1064-1072
    • Neu, H.C.1
  • 4
    • 34547619993 scopus 로고    scopus 로고
    • New tuberculosis therapeutics: A growing pipeline
    • M.K. Spigelman New tuberculosis therapeutics: a growing pipeline J. Infect. Dis. 196 2007 828 834
    • (2007) J. Infect. Dis. , vol.196 , pp. 828-834
    • Spigelman, M.K.1
  • 21
    • 0344958259 scopus 로고
    • Antimicrobial agents and susceptibility testing, section X
    • J.H. Jorgensen, F.C. Tonover, ASM Press Washington, DC
    • Antimicrobial agents and susceptibility testing, section X J.H. Jorgensen, F.C. Tonover, Clinical Microbiology 1995 ASM Press Washington, DC 1275 1434
    • (1995) Clinical Microbiology , pp. 1275-1434
  • 27
    • 15244350104 scopus 로고    scopus 로고
    • M.J. Hearn Chem. Abstr. 137 2002 20296 PCT Int. Appl. WO 02043668
    • (2002) Chem. Abstr. , vol.137 , pp. 20296
    • Hearn, M.J.1


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