Synthesis of new 4-isopropylthiazole hydrazide analogs and some derived clubbed triazole, oxadiazole ring systems - A novel class of potential antibacterial, antifungal and antitubercular agents

European Journal of Medicinal Chemistry

Volumn 44, Issue 11, 2009, Pages 4739-4746

  Mallikarjuna, B P ^a   Sastry, B S ^b   Suresh Kumar, G V ^c   Rajendraprasad, Y ^b   Chandrashekar, S M ^c   Sathisha, K ^d  

^a PES COLLEGE OF PHARMACY   (India)

^b ANDHRA UNIVERSITY   (India)

^c St Johns Pharmacy College   (India)

^d INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

4 Isopropylthiazole 2 carbohydrazide analogs; Antibacterial; Antifungal; Antitubercular; Broth dilution assay; Clubbed triazole thiazole derivatives; Cytotoxicity

Indexed keywords

1 (5 (4 ISOPROPYLTHIAZOL 2 YL) 2 (3,4,5 TRIMETHOXYPHENYL) 1,3,4 OXADIAZOL 3(2H)ETHANONE; 1 (5 (4 ISOPROPYLTHIAZOL 2 YL) 2 (4 HYDROXYPHENYL) 1,3,4 OXADIZOL 3(2H) YL)ETHANONE; 1 (5 (4 ISOPROPYLTHIAZOL 2 YL) 2 PHENYL 1,3,4 OXADIAZOL 3(2H) YL)ETHANONE; 3 ACETYL 5 (4 ISOPROPYLTHIAZOLE) 2 2,3 DIHYDRO 1,3,4 OXADIAZOLE DERIVATIVE; 4 AMINO 5 (4 ISOPROPYL 1,3 THIAZOL 2 YL) 4H 1,2,4 TRIAZOLE 3 THIOL; 4 ISOPROPYL 1,3 THIAZOLE 2 CARBOHYDRAZIDE; 4 ISOPROPYLTHIAZOLE HYDRAZIDE DERIVATIVE; 4 ISOPROPYLTHIZOLE 2 CARBOHYRAZIDE DERIVATIVE; 5 (4 ISOPROPYLTHIAZOL 2 YL) 1,3,4 OXADIAZOLE 2 THIOL; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; HYDRAZIDE DERIVATIVE; OXADIAZOLE DERIVATIVE; TRIAZOLE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; BROTH DILUTION; CARBON NUCLEAR MAGNETIC RESONANCE; CYTOTOXICITY; DRUG SYNTHESIS; INFRARED RADIATION; MASS SPECTROMETRY; MYCOBACTERIUM TUBERCULOSIS; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; ANTITUBERCULAR AGENTS; BACTERIA; CELL LINE, TUMOR; CELL SURVIVAL; FUNGI; HUMANS; HYDRAZINES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 70349911565     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.06.008     Document Type: Article

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