Merkel cell carcinoma of the gluteal region with ipsilateral metastasis into the pancreatic graft of a patient after combined kidney-pancreas transplantation

Onkologie

Volumn 33, Issue 10, 2010, Pages 520-524

  Krejí, Karel ^a   Tichý, Tomá ^a   Horák, Pavel ^a   Ciferská, Hana ^a   Hajdúch, Marián ^a   Srovnal, Josef ^a   Trojanec, Radek ^a   Zezulová, Michaela ^a   Zlevorová, Miloslava ^a   Kalinová, Lucie ^a   Zadrail, Josef ^a  

^a UNIVERSITY HOSPITAL OLOMOUC   (Czech Republic)

Author keywords

Kidney pancreas transplantation; Merkel cell carcinoma; Merkel cell polyomavirus; Pancreatic neoplasms

Indexed keywords

CYCLOPHOSPHAMIDE; DOXORUBICIN; INSULIN; PREDNISONE; RAPAMYCIN; SORAFENIB; STEM CELL FACTOR RECEPTOR; VASCULOTROPIN;

ADULT; ARTICLE; CANCER GROWTH; CANCER SURGERY; CASE REPORT; COMPARATIVE GENOMIC HYBRIDIZATION; COMPUTER ASSISTED TOMOGRAPHY; GRAFT FAILURE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY TRANSPLANTATION; LOW DRUG DOSE; LUNG EDEMA; MALE; MERKEL CELL TUMOR; METASTASIS; MULTIPLE CYCLE TREATMENT; PANCREAS INSUFFICIENCY; PANCREAS METASTASIS; PANCREAS TRANSPLANTATION; POSITRON EMISSION TOMOGRAPHY; UROSEPSIS;

AGED; BUTTOCKS; CARCINOMA, MERKEL CELL; HUMANS; KIDNEY TRANSPLANTATION; MALE; SKIN NEOPLASMS;

EID: 77957837950     PISSN: 0378584X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000319694     Document Type: Article

References (40)

1. Toker C: Trabecular carcinoma of the skin. Arch Dermatol 1972;105:107-110.
2. Koljonen V, Kukko H, Tukiainen E, Böhling T, Sankila R, Pukkala E, Sihto H, Joensuu H, Kyllönen L, Mäkisalo H: Incidence of Merkel cell carcinoma in renal transplant recipients. Nephrol Dial Transplant 2009;24:3231-3235.
3. Van Keymeulen A, Mascre G, Youseff KK, Harel I, Michaux C, De Geest N, Szpalski C, Achouri Y, Bloch W, Hassan BA, Blanpain C: Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis. J Cell Biol 2009;187:91-100.
4. Helmbold P, Schröter S, Holzhausen HJ, Hartschuh W, Marsch WC: Merkel cell carcinoma: a diagnostic and therapeutic challenge. Chirurg 2001;72:396-401.
5. Becker JC, Schrama D, Houben R: Merkel cell carcinoma. Cell Mol Life Sci 2009;66:1-8.
6. Swick BL, Ravdel L, Fitzpatrick JE, Robinson WA: Platelet-derived growth factor receptor alpha mutational status and immunohistochemical expression in Merkel cell carcinoma: implications for treatment with imatinib mesylate. J Cutan Pathol 2008;35:197-202.
7. Sandbrink F, Müller L, Fiebig HH, Kovacs G: Short communication: deletion 7q, trisomy 6 and 11 in a case of Merkel-cell carcinoma. Cancer Genet Cytogenet 1988;33:305-309.
8. Leonard JH, Leonard P, Kearsley JH: Chromosomes 1, 11, and 13 are frequently involved in karyotypic abnormalities in metastatic Merkel cell carcinoma. Cancer Genet Cytogenet 1993;67:65-70.
9. Chan WY, Chan AB, Liu AY, Chow JH, Ng EK, Chung SS: Chromosome 11 copy number gains and Epstein-Barr virus-associated malignancies. Diagn Mol Pathol 2001;10:223-227.
10. Yamazaki ML, Lum CA, Izumi AK: Primary cutaneous Richter syndrome: prognostic implications and review of the literature. J Am Acad Dermatol 2009;60:157-161.
11. Wiener F, Coleman A, Mock BA, Potter M: Non-random chromosomal change (trisomy 11) in murine plasmacytomas induced by an ABL-MYC retrovirus. Cancer Res 1995;55:1181-1188.
12. Weller K, Vetter-Kauzcok C, Kahler K, Hauschild A, Eigentler T, Pfohler C, Neuber K, Moll I, Krause M, Kneisel L: Guideline implementation in Merkel cell carcinoma: an example of a rare disease. Dtsch Arztebl 2006;103:2791-2796.
13. Girschik J, Fritschi L, Threlfall T, Slevin T: Deaths from non-melanoma skin cancer in Western Australia. Cancer Causes Control 2008;19:879-885.
14. Feng H, Shuda M, Chang Y, Moore PS: Clonal integration of a polyomavirus in human Merkel cell carcinoma. Science 2008;319:1096-1100.
15. Zur Hausen H: Novel human polyomaviruses-re-emergence of a well known virus family as possible human carcinogens. Int J Cancer 2008;123:247-250.
16. Kean JM, Rao S, Wang M, Garcea RL: Seroepi-demiology of human polyomaviruses. PLoS Pathog 2009;5:3:e1000363. www.plospathogens.org/article/ info:doi%2F10.1371%2Fjournal.ppat.1000363
17. Sihto H, Kukko H, Koljonen V, Sankila R, Böhling T, Joensuu H: Clinical factors associated with Merkel cell polyomavirus infection in Merkel cell carcinoma. J Natl Cancer Inst 2009;101:938-945.
18. Engels EA, Biggar RJ, Hall HI, Cross H, Crutch-field A, Finch JL, Grigg R, Hylton T, Pawlish KS, McNeel TS, Goedert JJ: Cancer risk in people infected with human immunodeficiency virus in the United States. Int J Cancer 2008;123:187-194.
19. Friedlaender MM, Rubinger D, Rosenbaum E, Amir G, Siguencia E: Temporary regression of Merkel cell carcinoma metastases after cessation of cyclosporine. Transplantation 2002;73:1849-1850.
20. Boratyska M, Watorek E, Smolska D, Patrzałek D, Klinger M: Anticancer effect of sirolimus in renal allograft recipients with de novo malignancies, Transplant Proc, 2007, 39, 2736-2739.
21. Goepfert H, Remmler D, Silva E, Wheeler B: Merkel cell carcinoma (endocrine carcinoma of the skin) of the head and neck. Arch Otolaryngol 1984;110:707-712.
22. Pectasides D, Pectasides M, Economopoulos T: Merkel cell cancer of the skin. Ann Oncol 2006;17:1489-1495.
23. Mehrany K, Otley CC, Weenig RH, Philips PK, Roenigk RK, Nguyen TH: A meta-analysis of the prognostic significance of sentinel lymph node status in Merkel cell carcinoma. Dermatol Surg 2002;28:113-117.
24. Kokoska ER, Kokoska MS, Collins BT, Stapleton DR, Wade TP: Early aggressive treatment for Merkel cell carcinoma improves outcome. Am J Surg 1997;174:688-693.
25. Boyle F, Pendlebury S, Bell D: Further insights into the natural history and management of primary cutaneous neuroendocrine (Merkel cell) carcinoma. Int J Radiat Oncol Biol Phys 1995; 31:315-323.
26. Veness MJ: Merkel cell carcinoma: improved outcome with the addition of adjuvant therapy. J Clin Oncol 2005;23:7235-7236.
27. National Comprehensive Cancer Network (NCCN) guidelines for cancer treatment: www.nccn.org/professionals/physician-gls/fguidelines.asp.
28. Poulsen M, Walpole E, Harvey J, Dickie G, O'Brien P, Keller J, Tripcony L, Rischin D: Weekly carboplatin reduces toxicity during synchronous chemoradiotherapy for Merkel cell carcinoma of skin. Int J Radiat Oncol Biol Phys 2008;72:1070-1074.
29. Tai PT, Yu E, Winquist E, Hammond A, Stitt L, Tonita J, Gilchrist J: Chemotherapy in neuroendo-crine/Merkel cell carcinoma of the skin: case series and review of 204 cases. J Clin Oncol 2000;18:2493-2499.
30. Becker J, Mauch C, Kortmann RD, Keilholz U, Bootz F, Garbe C, Hauschild A, Moll I: Short German guidelines: Merkel cell carcinoma. J Dtsch Dermatol Ges 2008;6(suppl 1):15-16.
31. Lenz HJ: Molecular markers in gastrointestinal cancer: targeted therapy and tailored chemotherapy. Onkologie 2004;27:12-14.
32. Brunner M, Thurnher D, Pammer J, Geleff S, Heiduschka G, Reinisch CM, Petzelbauer P, Erovic BM: Expression of VEGF-A/C, VEGF-R2, PDGF-alpha/beta, c-kit, EGFR, Her-2/Neu, Mcl-1 and Bmi-1 in Merkel cell carcinoma. Mod Pathol 2008;21:876-884.
33. Dean NM, Bennett CF: Antisense oligonucleotide-based therapeutics for cancer. Oncogene 2003;22: 9087-9096.
34. Krasagakis K, Krüger-Krasagakis S, Tzanakakis GN, Darivianaki K, Stathopoulos EN, Tosca AD: Interferon-alpha inhibits proliferation and induces apoptosis of merkel cell carcinoma in vitro. Cancer Invest 2008;26:562-568.
35. Bossuyt W, Kazanjian A, De Geest N, Van Kelst S, De Hertogh G, Geboes K, Boivin GP, Luciani J, Fuks F, Chuah M, VandenDriessche T, Marynen P, Cools J, Shroyer NF, Hassan BA: Atonal homolog 1 is a tumor suppressor gene. PLoS Biol 2009;7: 2:e1000039. www.plosbiology.org/article/info:doi/10.1371/journal.pbio. 1000039.
36. Pastrana DV, Tolstov YL, Becker JC, Moore PS, Chang Y, Buck CB: Quantitation of Human Seroresponsiveness to Merkel Cell Polyomavirus. PLoS Pathog 2009;5:9:e1000578. www.plospatho-gens.org/article/info:doi%2F10. 1371%2Fjournal.ppat.1000578.
37. Bachmeyer C, Alovor G, Chatelain D, Khuoy L, Turc Y, Danon O, Laurette F, Cazier A, N'Guyen V: Cystic metastasis of the pancreas indicating relapse of Merkel cell carcinoma. Pancreas 2002;24: 103-105.
38. Ouellette JR, Woodyard L, Toth L, Termuhlen PM: Merkel cell carcinoma metastatic to the head of the pancreas. JOP 2004;5:92-96.
39. Bachmann J, Kleeff J, Bergmann F, Shrikhande SV, Hartschuh W, Büchler MW, Friess H: Pancreatic metastasis of Merkel cell carcinoma and concomitant insulinoma: case report and literature review. World J Surg Oncol 2005;3:58. www.wjso.com/content/3/1/58.
40. Patel K, Siegel J, Somorin O, Podani J: A case of Merkel cell carcinoma metastasis to the head and the body of the pancreas. Internet J Gastroenterol 2009;8:1. www.ispub.com/journal/the-internet-journal-of-gastroenterology/volume- 8-number-116/article/a-case-of-merkel-cell-carcinoma-metastasis-to-the-head-and- the-body-of-the-pancreas.html.