Merkel cell carcinoma: A diagnostic and therapeutic challenge;Das Merkelzellcarcinom: Eine diagnostische und therapeutische Herausforderung

Chirurg

Volumn 72, Issue 4, 2001, Pages 396-401

  Helmbold, P ^a,b   Schroter S ^b   Holzhausen, H J ^b   Hartschuh, W ^c   Marsch, W Ch ^a  

^a MARTIN LUTHER UNIVERSITÄT HALLE WITTENBERG   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Chemotherapy; Merkel cell tumour; Octreotide; Radiation; Review

Indexed keywords

TUMOR MARKER;

ELECTRON MICROSCOPY; HUMAN; MERKEL CELL TUMOR; PATHOLOGY; PROGNOSIS; REVIEW; SKIN; SKIN TUMOR;

CARCINOMA, MERKEL CELL; HUMANS; MICROSCOPY, ELECTRON; PROGNOSIS; SKIN; SKIN NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 0035319950     PISSN: 00094722     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001040051320     Document Type: Article

References (38)

1. Alegre M, Puig L, Carreno R, Baiget M, et al (1997) Primary neuroendocrine carcinoma of the skin expresses tyrosinase mRNA: detection by a specific nested PCR technique. Dermatology 194: 334
2. Allen PJ, Zhang ZF, Coit DG (1999) Surgical management of Merkel cell carcinoma. Ann Surg 229: 97
3. Bischof M, van Kampen M, Huber P, Wannenmacher M (1999) Merkel cell carcinoma: the role of radiation therapy in general management. Strahlenther Onkol 175: 611
4. Boyle F, Pendlebury S, Bell D (1995) Further insights into the natural history and management of primary cutaneous neuroendocrine (Merkel cell) carcinoma. Int J Radiat Oncol Biol Phys 31: 315
5. Cirillo F, Filippini L, Lima GF, Caresana G, Alquati P (1997) Merkel cell tumor. Report of case and treatment with octreotide. Minerva Chir 52: 1359
6. De Wolff-Peeters C, Marien K, Mebis J, Desmet V (1980) A cutaneous APUDoma or Merkel cell tumor? A morphologically recognizable tumor with a biological and histological malignant aspect in contrast with its clinical behavior. Cancer 46: 1810
7. di Bartolomeo M, Bajetta E, Buzzoni R, Mariani L, et al (1996) Clinical efficacy of octreotide in the treatment of metastatic neuroendocrine tumors. A study by the Italian Trials in Medical Oncology Group. Cancer 77: 402
8. Eftekhari F, Wallace S, Silva EG, Lenzi R (1996) Merkel cell carcinoma of the skin: imaging and clinical features in 93 cases. Br J Radiol 69: 226
9. Erlandson RA (1994) Diagnostic transmission electron microscopy of tumors. Raven Press, New York, p 564
10. Fenig E, Brenner B, Njuguna E, Katz A, et al (2000) Oral etoposide for Merkel cell carcinoma in patients previously treated with intravenous etoposide. Am J Clin Oncol 23: 65
11. Garbe C (1996) Merkel-Zell-Tumor. In: Schmoll HJ, Höffken K, Possinger K (Hrsg) Kompendium Internistische Onkologie. Springer, Berlin Heidelberg New York, S 1475
12. Gould VE, Moll R, Moll I, Lee I, Franke WW (1985) Neuroendocrine (Merkel) cells of the skin: hyperplasias, dysplasias, and neoplasms. Lab Invest 52: 334
13. Haneke E (1985) Electron microscopy of Merkel cell carcinoma from formalin-fixed tissue. J Am Acad Dermatol 12: 487
14. Hartschuh W (1986) The Merkel cell. In: Bereiter-Hahn J, Matoltsy AG, Richards KS (eds) Biology of the integument, vol 2 Vertebrates. Springer, Berlin Heidelberg New York, p 605
15. Hartschuh W (1997) Das Merkelzellkarzinom. In: Garbe C, Dummer R, Kaufmann R, Tilgen W (Hrsg) Dermatologische Onkologie. Springer, Berlin Heidelberg New York, S 489
16. Hauschild A, Garbe C (1998) Kutanes neuroendokrines Karzinom (Merkelzell-Karzinom). Leitlinie zur Qualitätssicherung. Deutsche Dermatologische Gesellschaft und Berufsverband der Deutschen Dermatologen e. V. Hautarzt 48 [Suppl 1]: 27
17. Hauschild A, Garbe C, Rademacher D, Christophers E (1997) Der Merkel-Zell-Tumor der Haut. Dtsch Med Wochenschr 122: 753
18. Hill AD, Brady MS, Coit DG (1999) Intraoperative lymphatic mapping and sentinel lymph node biopsy for Merkel cell carcinoma. Br J Surg 86: 518
19. Kau RJ, Wagner-Manslau C, Saumweber D, Arnold W (1994) Nachweis von Somatostatinrezeptoren in Tumoren des KopfHals-Bereiches und ihre klinische Bedeutung. Laryngorhinootologie 73: 21
20. Kwekkeboom DJ, Hoff AM, Lamberts SW, Oei HY, Krenning EP (1992) Somatostatin analogue scintigraphy. A simple and sensitive method for the in vivo visualization of Merkel cell tumors and their metastases. Arch Dermatol 128: 818
21. Lampreave JL, Benard F, Alavi A, Jimenez-Hoyuela J, Fraker D (1998) PET evaluation of therapeutic limb perfusion in Merkel's cell carcinoma. J Nucl Med 39: 2087
22. LeBoit PE, Crutcher WA, Shapiro PE (1992) Pagetoid intraepidermal spread in Merkel cell (primary neuroendocrine) carcinoma of the skin. Am J Surg Pathol 16: 584
23. Lien HC, Tsai TF, Lee YY, Hsiao CH (1999) Merkel cell carcinoma and chronic arsenicism. J Am Acad Dermatol 41: 641
24. Meeuwissen JA, Bourne RG, Kearsley JH (1995) The importance of postoperative radiation therapy in the treatment of Merkel cell carcinoma. Int J Radiat Oncol Biol Phys 31: 325
25. Miller RW, Rabkin CS (1999) Merkel cell carcinoma and melanoma: etiological similarities and differences. Cancer Epidemiol Biomarkers Prev 8: 153
26. Moll I (1994) Die Merkelzelle. Hautarzt 45: 352
27. Moll R (1993) Cytokeratine als Differenzierungsmarker: Expressionsprofile von Epithelien und epithelialen Tumoren. G. Fischer, Stuttgart
28. Moll R, Waltering S, Gillardon F, Krause U, et al (1997) bcl-2-Genfamilie in Merkelzellkarzinomen. Verh Dtsch Ges Path 81: 171
29. Morrison WH, Peters LJ, Silva EG, Wendt CD, et al (1990) The essential role of radiation therapy in securing locoregional control of Merkel cell carcinoma. Int J Radiat Oncol Biol Phys 19: 583
30. O'Connor WJ, Roenigk RK, Brodland DG (1997) Merkel cell carcinoma. Comparison of Mohs micrographic surgery and wide excision in eighty-six patients. Dermatol Surg 23: 929
31. Penn I, First MR (1999) Merkel's cell carcinoma in organ recipients: report of 41 cases. Transplantation 68: 1717
32. Schmoeckel I, Engst R, Worret WI (1995) Das Merkelzellkarzinom - therapeutische Möglichkeiten. Z Dermatol 181: 120
33. Skelton HG, Smith KJ, Hitchcock CL, McCarthy WF, et al (1997) Merkel cell carcinoma: analysis of clinical, histologic, and immunohistologic features of 132 cases with relation to survival. J Am Acad Dermatol 37: 734
34. Smith DE, Bielamowicz S, Kagan AR, Anderson PJ, Peddada AV (1995) Cutaneous neuroendocrine (Merkel cell) carcinoma. A report of 35 cases. Am J Clin Oncol 18: 199
35. Suntharalingam M, Rudoltz MS, Mendenhall WM, Parsons JT, et al (1995) Radiotherapy for Merkel cell carcinoma of the skin of the head and neck. Head Neck 17: 96
36. Toker C (1972) Trabecular carcinoma of the skin. Arch Dermatol 105: 107
37. Voog E, Biron P, Martin JP, Blay JY (1999) Chemotherapy for patients with locally advanced or metastatic Merkel cell carcinoma. Cancer 85: 2589
38. Wätzig V, Katenkamp D (1987) Disseminiert neurokutane Karzinome der Haut. Z Hautkr 62: 1105