Isolation of SPINK6 in human skin: Selective inhibitor of kallikrein-related peptidases

Journal of Biological Chemistry

Volumn 285, Issue 42, 2010, Pages 32174-32181

  Meyer Hoffert, Ulf ^a   Wu, Zhihong ^a   Kantyka, Tomasz ^a,b   Fischer, Jan ^a   Latendorf, Ties ^a   Hansmann, Britta ^a   Bartels, Joachim ^a   He, Yinghong ^a   Gläser, Regine ^a   Schröder, Jens Michael ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

APPARENT K; ATOPIC DERMATITIS; CHYMASE; ELASTASE; EX-VIVO; HUMAN SKIN; IMMUNOHISTOCHEMICAL ANALYSIS; KERATINOCYTE DIFFERENTIATION; LOW LEVEL; MAST CELLS; SEBACEOUS GLAND; SELECTIVE INHIBITION; SELECTIVE INHIBITORS; SPECIFIC INHIBITORS; STRATUM CORNEUM; STRATUM GRANULOSUM; THERAPEUTIC POTENTIALS;

DERMATITIS;

CATHEPSIN G; CHYMASE; ENZYME INHIBITOR; KALLIKREIN RELATED PEPTIDASE; KALLIKREIN RELATED PEPTIDASE 14; KALLIKREIN RELATED PEPTIDASE 5; KALLIKREIN RELATED PEPTIDASE 7; KALLIKREIN RELATED PEPTIDASE 8; LEUKOCYTE ELASTASE; LYMPHOEPITHELIAL KAZAL TYPE INHIBITOR; LYMPHOEPITHELIAL KAZAL TYPE INHIBITOR 2; MATRIPTASE; MESSENGER RNA; PEPTIDASE; PLASMIN; PROSTASIN; PROTEIN SPINK6; RECOMBINANT PROTEIN; SERINE PROTEINASE INHIBITOR; SERINE PROTEINASE INHIBITOR KAZAL TYPE 6; THROMBIN; TRYPSIN; UNCLASSIFIED DRUG;

ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ISOLATION; HUMAN; HUMAN TISSUE; KERATINOCYTE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SEBACEOUS GLAND; SKIN; SKIN APPENDAGE; STRATUM CORNEUM; SWEAT GLAND; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; BASE SEQUENCE; HUMANS; ISOENZYMES; KALLIKREINS; MOLECULAR SEQUENCE DATA; PROTEASE INHIBITORS; PROTEINASE INHIBITORY PROTEINS, SECRETORY; SEQUENCE ALIGNMENT; SERINE ENDOPEPTIDASES; SKIN; SKIN DISEASES; TISSUE DISTRIBUTION;

EID: 77957808698     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.091850     Document Type: Article

References (35)

1. Meyer-Hoffert, U. (2009) Arch. Immunol. Ther. Exp. 57, 345-354
2. Yousef, G. M., and Diamandis, E. P. (2001) Endocr. Rev. 22, 184-204
3. Komatsu, N., Suga, Y., Saijoh, K., Liu, A. C., Khan, S., Mizuno, Y., Ikeda, S., Wu, H. K., Jayakumar, A., Clayman, G. L., Shirasaki, F., Takehara, K., and Diamandis, E. P. (2006) J. Invest. Dermatol. 126, 2338-2342
4. Komatsu, N., Takata, M., Otsuki, N., Toyama, T., Ohka, R., Takehara, K., and Saijoh, K. (2003) J. Invest. Dermatol. 121, 542-549
5. Komatsu, N., Saijoh, K., Toyama, T., Ohka, R., Otsuki, N., Hussack, G., Takehara, K., and Diamandis, E. P. (2005) Br. J. Dermatol. 153, 274-281
6. Hansson, L., Bäckman, A., Ny, A., Edlund, M., Ekholm, E., Ekstrand Hammarström, B., Törnell, J., Wallbrandt, P., Wennbo, H., and Egelrud, T. (2002) J. Invest. Dermatol. 118, 444-449
7. Simon, M., Jonca, N., Guerrin, M., Haftek, M., Bernard, D., Caubet, C., Egelrud, T., Schmidt, R., and Serre, G. (2001) J. Biol. Chem. 276, 20292-20299
8. Caubet, C., Jonca, N., Brattsand, M., Guerrin, M., Bernard, D., Schmidt, R., Egelrud, T., Simon, M., and Serre, G. (2004) J. Invest. Dermatol. 122, 1235-1244
9. Egelrud, T., Brattsand, M., Kreutzmann, P., Walden, M., Vitzithum, K., Marx, U. C., Forssmann, W. G., and Mägert, H. J. (2005) Br. J. Dermatol. 153, 1200-1203
10. Borgoño, C. A., Michael, I. P., Komatsu, N., Jayakumar, A., Kapadia, R., Clayman, G. L., Sotiropoulou, G., and Diamandis, E. P. (2007) J. Biol. Chem. 282, 3640-3652
11. Chavanas, S., Bodemer, C., Rochat, A., Hamel-Teillac, D., Ali, M., Irvine, A. D., Bonafé, J. L., Wilkinson, J., Taïeb, A., Barrandon, Y., Harper, J. I., de Prost, Y., and Hovnanian, A. (2000) Nat. Genet. 25, 141-142
12. Griffiths, W. A. D., Leigh, I. M., and Judge, M. R. (1998) in Textbook of Dermatology (Champion, R. H., Breathnach, S. M., Burns, D. A., and Burton, J. L., eds) Blackwell Science, Oxford
13. Mägert, H. J., Ständker, L., Kreutzmann, P., Zucht, H. D., Reinecke, M., Sommerhoff, C. P., Fritz, H., and Forssmann, W. G. (1999) J. Biol. Chem. 274, 21499-21502
14. Meyer-Hoffert, U., Wu, Z., and Schröder, J. M. (2009) PLoS ONE 4, e4372
15. Brattsand, M., Stefansson, K., Hubiche, T., Nilsson, S. K., and Egelrud, T. (2009) J. Invest. Dermatol. 129, 1656-1665
16. Kent, W. J. (2002) Genome Res. 12, 656-664
17. Tatusova, T. A., and Madden, T. L. (1999) FEMS Microbiol. Lett. 174, 247-250
18. Schultz, J., Milpetz, F., Bork, P., and Ponting, C. P. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 5857-5864
19. Wu, Z., Hansmann, B., Meyer-Hoffert, U., Glaser, R., and Schröder, J. M. (2009) PLoS ONE 4, e5227
20. Hale, J. E., Butler, J. P., Gelfanova, V., You, J. S., and Knierman, M. D. (2004) Anal. Biochem. 333, 174-181
21. Wu, Z., Meyer-Hoffert, U., Reithmayer, K., Paus, R., Hansmann, B., He, Y., Bartels, J., Gläser, R., Harder, J., and Schröder, J. M. (2009) J. Invest. Dermatol. 129, 1446-1458
22. Lundström, A., and Egelrud, T. (1988) J. Invest. Dermatol. 91, 340-343
23. Ishida-Yamamoto, A., Deraison, C., Bonnart, C., Bitoun, E., Robinson, R., O'Brien, T. J., Wakamatsu, K., Ohtsubo, S., Takahashi, H., Hashimoto, Y., Dopping-Hepenstal, P. J., McGrath, J. A., Iizuka, H., Richard, G., and Hovnanian, A. (2005) J. Invest. Dermatol. 124, 360-366
24. Sondell, B., Thornell, L. E., and Egelrud, T. (1995) J. Invest. Dermatol. 104, 819-823
25. Ishida-Yamamoto, A., Simon, M., Kishibe, M., Miyauchi, Y., Takahashi, H., Yoshida, S., O'Brien, T. J., Serre, G., and Iizuka, H. (2004) J. Invest. Dermatol. 122, 1137-1144
26. Mitsudo, K., Jayakumar, A., Henderson, Y., Frederick, M. J., Kang, Y., Wang, M., El-Naggar, A. K., and Clayman, G. L. (2003) Biochemistry 42, 3874-3881
27. Deraison, C., Bonnart, C., Lopez, F., Besson, C., Robinson, R., Jayakumar, A., Wagberg, F., Brattsand, M., Hachem, J. P., Leonardsson, G., and Hovnanian, A. (2007) Mol. Biol. Cell 18, 3607-3619
28. Schechter, N. M., Choi, E. J., Wang, Z. M., Hanakawa, Y., Stanley, J. R., Kang, Y., Clayman, G. L., and Jayakumar, A. (2005) Biol. Chem. 386, 1173-1184
29. Stefansson, K., Brattsand, M., Roosterman, D., Kempkes, C., Bocheva, G., Steinhoff, M., and Egelrud, T. (2008) J. Invest. Dermatol. 128, 18-25
30. Steinhoff, M., Buddenkotte, J., Shpacovitch, V., Rattenholl, A., Moormann, C., Vergnolle, N., Luger, T. A., and Hollenberg, M. D. (2005) Endocr. Rev. 26, 1-43
31. Hachem, J. P., Houben, E., Crumrine, D., Man, M. Q., Schurer, N., Roelandt, T., Choi, E. H., Uchida, Y., Brown, B. E., Feingold, K. R., and Elias, P. M. (2006) J. Invest. Dermatol. 126, 2074-2086
32. Briot, A., Deraison, C., Lacroix, M., Bonnart, C., Robin, A., Besson, C., Dubus, P., and Hovnanian, A. (2009) J. Exp. Med. 206, 1135-1147
33. Ziegler, S. F., and Liu, Y. J. (2006) Nat. Immunol. 7, 709-714
34. Voegeli, R., Rawlings, A. V., Breternitz, M., Doppler, S., Schreier, T., and Fluhr, J. W. (2009) Br. J. Dermatol. 161, 70-77
35. Shaw, J. L., and Diamandis, E. P. (2007) Clin. Chem. 53, 1423-1432