메뉴 건너뛰기




Volumn 126, Issue 4, 2010, Pages 681-687

Asthma in the elderly: Diagnosis and management

Author keywords

Asthma; diagnosis; elderly; environmental exposures; innate immunity; management; microbial colonization

Indexed keywords

ADRENERGIC RECEPTOR STIMULATING AGENT; ANTIFUNGAL AGENT; BRONCHODILATING AGENT; ENDOTOXIN; GLUCOCORTICOID; IMMUNOGLOBULIN E; LEUKOTRIENE RECEPTOR BLOCKING AGENT; PROTEINASE; THEOPHYLLINE; TOLL LIKE RECEPTOR 4;

EID: 77957807579     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2010.05.035     Document Type: Review
Times cited : (64)

References (56)
  • 1
    • 79959344460 scopus 로고    scopus 로고
    • Expert Panel Report 3 (EPR-3): Guidelines for the diagnosis and management of asthma - Summary Report 2007
    • Expert Panel Report 3 (EPR-3): guidelines for the diagnosis and management of asthma - summary Report 2007 J Allergy Clin Immunol 120 suppl 2007 S94 S138
    • (2007) J Allergy Clin Immunol , vol.120 , Issue.SUPPL.
  • 2
    • 38449106142 scopus 로고    scopus 로고
    • Effect of aging on respiratory system physiology and immunology
    • G. Sharma, and J. Goodwin Effect of aging on respiratory system physiology and immunology Clin Interv Aging 1 2006 253 260
    • (2006) Clin Interv Aging , vol.1 , pp. 253-260
    • Sharma, G.1    Goodwin, J.2
  • 3
    • 34548503905 scopus 로고    scopus 로고
    • Effect of ageing on pulmonary inflammation, airway hyperresponsiveness and T and B cell responses in antigen-sensitized and -challenged mice
    • P.J. Busse, T.F. Zhang, K. Srivastava, B. Schofield, and X.M. Li Effect of ageing on pulmonary inflammation, airway hyperresponsiveness and T and B cell responses in antigen-sensitized and -challenged mice Clin Exp Allergy 37 2007 1392 1403
    • (2007) Clin Exp Allergy , vol.37 , pp. 1392-1403
    • Busse, P.J.1    Zhang, T.F.2    Srivastava, K.3    Schofield, B.4    Li, X.M.5
  • 4
    • 0026344461 scopus 로고
    • Findings before diagnoses of asthma among the elderly in a longitudinal study of a general population sample
    • B. Burrows, M.D. Lebowitz, R.A. Barbee, and M.G. Cline Findings before diagnoses of asthma among the elderly in a longitudinal study of a general population sample J Allergy Clin Immunol 88 1991 870 877
    • (1991) J Allergy Clin Immunol , vol.88 , pp. 870-877
    • Burrows, B.1    Lebowitz, M.D.2    Barbee, R.A.3    Cline, M.G.4
  • 5
    • 0033022464 scopus 로고    scopus 로고
    • The natural history of asthma in adults: The problem of irreversibility
    • C.E. Reed The natural history of asthma in adults: the problem of irreversibility J Allergy Clin Immunol 103 1999 539 547
    • (1999) J Allergy Clin Immunol , vol.103 , pp. 539-547
    • Reed, C.E.1
  • 7
    • 0031440696 scopus 로고    scopus 로고
    • Significance of emphysema observed on computed tomography scan in asthma
    • F. Paganin, D. Jaffuel, and J. Bousquet Significance of emphysema observed on computed tomography scan in asthma Eur Respir J 10 1997 2446 2448
    • (1997) Eur Respir J , vol.10 , pp. 2446-2448
    • Paganin, F.1    Jaffuel, D.2    Bousquet, J.3
  • 8
    • 0007917440 scopus 로고    scopus 로고
    • High-resolution computed tomography in patients with bronchial asthma: Correlation with clinical features, pulmonary functions and bronchial hyperresponsiveness
    • J.W. Park, Y.K. Hong, C.W. Kim, D.K. Kim, K.O. Choe, and C.S. Hong High-resolution computed tomography in patients with bronchial asthma: correlation with clinical features, pulmonary functions and bronchial hyperresponsiveness J Investig Allergol Clin Immunol 7 1997 186 192
    • (1997) J Investig Allergol Clin Immunol , vol.7 , pp. 186-192
    • Park, J.W.1    Hong, Y.K.2    Kim, C.W.3    Kim, D.K.4    Choe, K.O.5    Hong, C.S.6
  • 10
    • 0033917518 scopus 로고    scopus 로고
    • Tissue remodeling as a feature of persistent asthma
    • A.M. Vignola, J. Kips, and J. Bousquet Tissue remodeling as a feature of persistent asthma J Allergy Clin Immunol 105 2000 1041 1053
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 1041-1053
    • Vignola, A.M.1    Kips, J.2    Bousquet, J.3
  • 11
    • 0025773838 scopus 로고
    • Role of mast cell and neutrophil proteases in airway secretion
    • J.A. Nadel Role of mast cell and neutrophil proteases in airway secretion Am Rev Respir Dis 144 suppl 1991 S48 S51
    • (1991) Am Rev Respir Dis , vol.144 , Issue.SUPPL.
    • Nadel, J.A.1
  • 12
    • 45949100430 scopus 로고    scopus 로고
    • Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity
    • V. Shpacovitch, M. Feld, M.D. Hollenberg, T.A. Luger, and M. Steinhoff Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity J Leukoc Biol 83 2008 1309 1322
    • (2008) J Leukoc Biol , vol.83 , pp. 1309-1322
    • Shpacovitch, V.1    Feld, M.2    Hollenberg, M.D.3    Luger, T.A.4    Steinhoff, M.5
  • 13
    • 1342324768 scopus 로고    scopus 로고
    • Cutting edge: Activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma
    • V. Redecke, H. Hacker, S.K. Datta, A. Fermin, P.M. Pitha, and D.H. Broide Cutting edge: activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma J Immunol 172 2004 2739 2743
    • (2004) J Immunol , vol.172 , pp. 2739-2743
    • Redecke, V.1    Hacker, H.2    Datta, S.K.3    Fermin, A.4    Pitha, P.M.5    Broide, D.H.6
  • 14
    • 7944224566 scopus 로고    scopus 로고
    • The role of protease activation of inflammation in allergic respiratory diseases
    • C.E. Reed, and H. Kita The role of protease activation of inflammation in allergic respiratory diseases J Allergy Clin Immunol 114 2004 997 1008
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 997-1008
    • Reed, C.E.1    Kita, H.2
  • 15
    • 34548505283 scopus 로고    scopus 로고
    • Inflammatory effect of environmental proteases on airway mucosa
    • C.E. Reed Inflammatory effect of environmental proteases on airway mucosa Curr Allergy Asthma Rep 7 2007 368 374
    • (2007) Curr Allergy Asthma Rep , vol.7 , pp. 368-374
    • Reed, C.E.1
  • 16
    • 33745074367 scopus 로고    scopus 로고
    • House dust mite major allergens der p 1 and der p 5 activate human airway-derived epithelial cells by protease-dependent and protease-independent mechanisms
    • H.F. Kauffman, M. Tamm, J.A. Timmerman, and P. Borger House dust mite major allergens Der p 1 and Der p 5 activate human airway-derived epithelial cells by protease-dependent and protease-independent mechanisms Clin Mol Allergy 4 2006 5
    • (2006) Clin Mol Allergy , vol.4 , pp. 5
    • Kauffman, H.F.1    Tamm, M.2    Timmerman, J.A.3    Borger, P.4
  • 17
    • 0034796380 scopus 로고    scopus 로고
    • The proteolytic activity of the major dust mite allergen der p 1 enhances the IgE antibody response to a bystander antigen
    • L. Gough, H.F. Sewell, and F. Shakib The proteolytic activity of the major dust mite allergen Der p 1 enhances the IgE antibody response to a bystander antigen Clinical & Experimental Allergy 31 2001 1594 1598
    • (2001) Clinical & Experimental Allergy , vol.31 , pp. 1594-1598
    • Gough, L.1    Sewell, H.F.2    Shakib, F.3
  • 18
    • 0035184146 scopus 로고    scopus 로고
    • Protease-activated receptors in human airways: Upregulation of PAR-2 in respiratory epithelium from patients with asthma
    • D.A. Knight, S. Lim, A.K. Scaffidi, N. Roche, K.F. Chung, and G.A. Stewart Protease-activated receptors in human airways: upregulation of PAR-2 in respiratory epithelium from patients with asthma J Allergy Clin Immunol 108 2001 797 803
    • (2001) J Allergy Clin Immunol , vol.108 , pp. 797-803
    • Knight, D.A.1    Lim, S.2    Scaffidi, A.K.3    Roche, N.4    Chung, K.F.5    Stewart, G.A.6
  • 20
    • 65649087828 scopus 로고    scopus 로고
    • Patients with mild-to-moderate asthma may develop clinically significant chronic obstructive pulmonary disease
    • Y. Tsuda, T. Noguchi, H. Mochizuki, F. Makino, Y. Nanjo, and M. Sawabe Patients with mild-to-moderate asthma may develop clinically significant chronic obstructive pulmonary disease Respirology 14 2009 529 536
    • (2009) Respirology , vol.14 , pp. 529-536
    • Tsuda, Y.1    Noguchi, T.2    Mochizuki, H.3    Makino, F.4    Nanjo, Y.5    Sawabe, M.6
  • 22
    • 0034904034 scopus 로고    scopus 로고
    • Endotoxin-stimulated innate immunity: A contributing factor for asthma
    • C.E. Reed, and D.K. Milton Endotoxin-stimulated innate immunity: a contributing factor for asthma J Allergy Clin Immunol 108 2001 157 166
    • (2001) J Allergy Clin Immunol , vol.108 , pp. 157-166
    • Reed, C.E.1    Milton, D.K.2
  • 23
    • 30344449466 scopus 로고    scopus 로고
    • Endotoxin exposure is a risk factor for asthma: The national survey of endotoxin in United States housing
    • P.S. Thorne, K. Kulhankova, M. Yin, R. Cohn, S.J. Arbes Jr., and D.C. Zeldin Endotoxin exposure is a risk factor for asthma: the national survey of endotoxin in United States housing Am J Respir Crit Care Med 172 2005 1371 1377
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 1371-1377
    • Thorne, P.S.1    Kulhankova, K.2    Yin, M.3    Cohn, R.4    Arbes Jr., S.J.5    Zeldin, D.C.6
  • 24
    • 33646814732 scopus 로고    scopus 로고
    • Elevated concentrations of endotoxin in indoor air due to cigarette smoking
    • A. Sebastian, C. Pehrson, and L. Larsson Elevated concentrations of endotoxin in indoor air due to cigarette smoking J Environ Monit 8 2006 519 522
    • (2006) J Environ Monit , vol.8 , pp. 519-522
    • Sebastian, A.1    Pehrson, C.2    Larsson, L.3
  • 25
    • 0033034660 scopus 로고    scopus 로고
    • Bacterial endotoxin is an active component of cigarette smoke
    • J.D. Hasday, R. Bascom, J.J. Costa, T. Fitzgerald, and W. Dubin Bacterial endotoxin is an active component of cigarette smoke Chest 115 1999 829 835
    • (1999) Chest , vol.115 , pp. 829-835
    • Hasday, J.D.1    Bascom, R.2    Costa, J.J.3    Fitzgerald, T.4    Dubin, W.5
  • 26
    • 0035891743 scopus 로고    scopus 로고
    • Role of latent viral infections in chronic obstructive pulmonary disease and asthma
    • J.C. Hogg Role of latent viral infections in chronic obstructive pulmonary disease and asthma Am J Respir Crit Care Med 164 suppl 2001 S71 S75
    • (2001) Am J Respir Crit Care Med , vol.164 , Issue.SUPPL.
    • Hogg, J.C.1
  • 29
    • 0036152623 scopus 로고    scopus 로고
    • Molecular mechanisms of decreased steroid responsiveness induced by latent adenoviral infection in allergic lung inflammation
    • K. Yamada, W.M. Elliott, R. Brattsand, A. Valeur, J.C. Hogg, and S. Hayashi Molecular mechanisms of decreased steroid responsiveness induced by latent adenoviral infection in allergic lung inflammation J Allergy Clin Immunol 109 2002 35 42
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 35-42
    • Yamada, K.1    Elliott, W.M.2    Brattsand, R.3    Valeur, A.4    Hogg, J.C.5    Hayashi, S.6
  • 30
    • 0032954535 scopus 로고    scopus 로고
    • PCR detection of viral nucleic acid in fatal asthma: Is the lower respiratory tract a reservoir for common viruses?
    • V. Macek, A. Dakhama, J.C. Hogg, F.H. Green, B.K. Rubin, and R.G. Hegele PCR detection of viral nucleic acid in fatal asthma: is the lower respiratory tract a reservoir for common viruses? Can Respir J 6 1999 37 43
    • (1999) Can Respir J , vol.6 , pp. 37-43
    • MacEk, V.1    Dakhama, A.2    Hogg, J.C.3    Green, F.H.4    Rubin, B.K.5    Hegele, R.G.6
  • 32
    • 70350053513 scopus 로고    scopus 로고
    • Prevalence of asthma among adult females and males in the United States: Results from the National Health and Nutrition Examination Survey (NHANES), 2001-2004
    • M.K. McHugh, E. Symanski, L.A. Pompeii, and G.L. Delclos Prevalence of asthma among adult females and males in the United States: results from the National Health and Nutrition Examination Survey (NHANES), 2001-2004 J Asthma 46 2009 759 766
    • (2009) J Asthma , vol.46 , pp. 759-766
    • McHugh, M.K.1    Symanski, E.2    Pompeii, L.A.3    Delclos, G.L.4
  • 35
    • 0028351043 scopus 로고
    • Asthma mortality and death certification in Northern Ireland
    • S.C. Wright, A.E. Evans, D.G. Sinnamon, and J. MacMahon Asthma mortality and death certification in Northern Ireland Thorax 49 1994 141 143
    • (1994) Thorax , vol.49 , pp. 141-143
    • Wright, S.C.1    Evans, A.E.2    Sinnamon, D.G.3    MacMahon, J.4
  • 36
    • 0031037873 scopus 로고    scopus 로고
    • Incidence and outcomes of asthma in the elderly. A population-based study in Rochester, Minnesota [see comments]
    • B.A. Bauer, C.E. Reed, J.W. Yunginger, P.C. Wollan, and M.D. Silverstein Incidence and outcomes of asthma in the elderly. A population-based study in Rochester, Minnesota [see comments] Chest 111 1997 303 310
    • (1997) Chest , vol.111 , pp. 303-310
    • Bauer, B.A.1    Reed, C.E.2    Yunginger, J.W.3    Wollan, P.C.4    Silverstein, M.D.5
  • 37
    • 0028075468 scopus 로고
    • Melton LJ3, O'Fallon WM, Yunginger JW. Long-term survival of a cohort of community residents with asthma
    • M.D. Silverstein, C.E. Reed, and E.J. O'Connell Melton LJ3, O'Fallon WM, Yunginger JW. Long-term survival of a cohort of community residents with asthma N Engl J Med 331 1994 1537 1541
    • (1994) N Engl J Med , vol.331 , pp. 1537-1541
    • Silverstein, M.D.1    Reed, C.E.2    O'Connell, E.J.3
  • 38
    • 0026507737 scopus 로고
    • Mortality and decline in lung function in 213 adults with bronchial asthma: A ten-year follow up
    • C.S. Ulrik, V. Backer, and A. Dirksen Mortality and decline in lung function in 213 adults with bronchial asthma: a ten-year follow up J Asthma 29 1992 29 38
    • (1992) J Asthma , vol.29 , pp. 29-38
    • Ulrik, C.S.1    Backer, V.2    Dirksen, A.3
  • 39
    • 0026540917 scopus 로고
    • Variations in asthma hospitalizations and deaths in New York City
    • W. Carr, L. Zeitel, and K. Weiss Variations in asthma hospitalizations and deaths in New York City Am J Public Health 82 1992 59 65
    • (1992) Am J Public Health , vol.82 , pp. 59-65
    • Carr, W.1    Zeitel, L.2    Weiss, K.3
  • 40
    • 0025304564 scopus 로고
    • Seasonal trends in US asthma hospitalizations and mortality
    • K.B. Weiss Seasonal trends in US asthma hospitalizations and mortality JAMA 263 1990 2323 2328
    • (1990) JAMA , vol.263 , pp. 2323-2328
    • Weiss, K.B.1
  • 41
    • 28844483009 scopus 로고    scopus 로고
    • Asthma and risk of death from lung cancer: NHANES II Mortality Study
    • D.W. Brown, K.E. Young, R.F. Anda, and W.H. Giles Asthma and risk of death from lung cancer: NHANES II Mortality Study J Asthma 42 2005 597 600
    • (2005) J Asthma , vol.42 , pp. 597-600
    • Brown, D.W.1    Young, K.E.2    Anda, R.F.3    Giles, W.H.4
  • 44
    • 70350482636 scopus 로고    scopus 로고
    • The effects of antifungal therapy on severe asthma with fungal sensitization and allergic bronchopulmonary aspergillosis
    • A.C. Pasqualotto, G. Powell, R. Niven, and D.W. Denning The effects of antifungal therapy on severe asthma with fungal sensitization and allergic bronchopulmonary aspergillosis Respirology 14 2009 1121 1127
    • (2009) Respirology , vol.14 , pp. 1121-1127
    • Pasqualotto, A.C.1    Powell, G.2    Niven, R.3    Denning, D.W.4
  • 46
    • 58349115630 scopus 로고    scopus 로고
    • Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: The Fungal Asthma Sensitization Trial (FAST) study
    • D.W. Denning, B.R. O'Driscoll, G. Powell, F. Chew, G.T. Atherton, and A. Vyas Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: the Fungal Asthma Sensitization Trial (FAST) study Am J Respir Crit Care Med 179 2009 11 18
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 11-18
    • Denning, D.W.1    O'Driscoll, B.R.2    Powell, G.3    Chew, F.4    Atherton, G.T.5    Vyas, A.6
  • 48
    • 70349584616 scopus 로고    scopus 로고
    • Fungal rhinosinusitis: A categorization and definitional schema addressing current controversies
    • A. Chakrabarti, D.W. Denning, B.J. Ferguson, J. Ponikau, W. Buzina, and H. Kita Fungal rhinosinusitis: a categorization and definitional schema addressing current controversies Laryngoscope 119 2009 1809 1818
    • (2009) Laryngoscope , vol.119 , pp. 1809-1818
    • Chakrabarti, A.1    Denning, D.W.2    Ferguson, B.J.3    Ponikau, J.4    Buzina, W.5    Kita, H.6
  • 49
    • 74549175386 scopus 로고    scopus 로고
    • The utility of antifungal agents for asthma
    • R.B. Gore The utility of antifungal agents for asthma Curr Opin Pulm Med 16 2010 36 41
    • (2010) Curr Opin Pulm Med , vol.16 , pp. 36-41
    • Gore, R.B.1
  • 50
    • 0037445151 scopus 로고    scopus 로고
    • Theophylline: New perspectives for an old drug
    • P.J. Barnes Theophylline: new perspectives for an old drug Am J Respir Crit Care Med 167 2003 813 818
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 813-818
    • Barnes, P.J.1
  • 51
    • 57349099228 scopus 로고    scopus 로고
    • Emerging pharmacotherapies for COPD
    • P.J. Barnes Emerging pharmacotherapies for COPD Chest 134 2008 1278 1286
    • (2008) Chest , vol.134 , pp. 1278-1286
    • Barnes, P.J.1
  • 52
    • 77954686490 scopus 로고    scopus 로고
    • Evaluating Safety of Long-Acting Beta Agonists (LABAs) in Patients with Asthma
    • B. Bian, C.M. Kelton, P.R. Wigle, and J.J. Guo Evaluating Safety of Long-Acting Beta Agonists (LABAs) in Patients with Asthma Curr Drug Saf 2010 [Epub ahead of print]
    • (2010) Curr Drug Saf
    • Bian, B.1    Kelton, C.M.2    Wigle, P.R.3    Guo, J.J.4
  • 53
    • 75849142220 scopus 로고    scopus 로고
    • Safety of formoterol in patients with asthma: Combined analysis of data from double-blind, randomized controlled trials
    • H. Nelson, C. Bonuccelli, F. Radner, A. Ottosson, K.J. Carroll, and T.L. Andersson Safety of formoterol in patients with asthma: combined analysis of data from double-blind, randomized controlled trials J Allergy Clin Immunol 125 2010 390 396
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 390-396
    • Nelson, H.1    Bonuccelli, C.2    Radner, F.3    Ottosson, A.4    Carroll, K.J.5    Andersson, T.L.6
  • 54
    • 73449095250 scopus 로고    scopus 로고
    • Meta-analysis of the risk of mortality with salmeterol and the effect of concomitant inhaled corticosteroid therapy
    • M. Weatherall, M. Wijesinghe, K. Perrin, M. Harwood, and R. Beasley Meta-analysis of the risk of mortality with salmeterol and the effect of concomitant inhaled corticosteroid therapy Thorax 65 2010 39 43
    • (2010) Thorax , vol.65 , pp. 39-43
    • Weatherall, M.1    Wijesinghe, M.2    Perrin, K.3    Harwood, M.4    Beasley, R.5
  • 55
    • 33646556210 scopus 로고    scopus 로고
    • Anticholinergic agents in asthma: Chronic bronchodilator therapy, relief of acute severe asthma, reduction of chronic viral inflammation and prevention of airway remodeling
    • H. Kanazawa Anticholinergic agents in asthma: chronic bronchodilator therapy, relief of acute severe asthma, reduction of chronic viral inflammation and prevention of airway remodeling Curr Opin Pulm Med 12 2006 60 67
    • (2006) Curr Opin Pulm Med , vol.12 , pp. 60-67
    • Kanazawa, H.1
  • 56
    • 38449113726 scopus 로고    scopus 로고
    • Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: A comparison
    • I.S. Bos, R. Gosens, A.B. Zuidhof, D. Schaafsma, A.J. Halayko, and H. Meurs Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: a comparison Eur Respir J 30 2007 653 661
    • (2007) Eur Respir J , vol.30 , pp. 653-661
    • Bos, I.S.1    Gosens, R.2    Zuidhof, A.B.3    Schaafsma, D.4    Halayko, A.J.5    Meurs, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.