메뉴 건너뛰기




Volumn 17, Issue 13, 2010, Pages 1016-1026

Potential of garlic and its active constituent, S-allyl cysteine, as antihypertensive and cardioprotective in presence of captopril

Author keywords

ACE inhibition; Captopril; Garlic; Interaction; Isobolographic analysis; S allyl cysteine sulphoxide; Synergy effect

Indexed keywords

ANTIHYPERTENSIVE AGENT; CAPTOPRIL; CATALASE; CHOLESTEROL; CREATINE KINASE MB; CYSTEINE DERIVATIVE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FRUCTOSE; GARLIC EXTRACT; GLUCOSE; ISOPRENALINE; LACTATE DEHYDROGENASE; S ALLYL CYSTEINE SULPHOXIDE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 77957803842     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2010.07.012     Document Type: Article
Times cited : (105)

References (58)
  • 1
    • 0030029823 scopus 로고    scopus 로고
    • Therapeutic action of garlic constituents
    • Agarwal K.C. Therapeutic action of garlic constituents. Med. Res. Rev. 1996, 16:11-124.
    • (1996) Med. Res. Rev. , vol.16 , pp. 11-124
    • Agarwal, K.C.1
  • 2
    • 0029094911 scopus 로고
    • Consumption of garlic, clove a day could be beneficial in preventing thrombosis
    • Ali M., Thomson M. Consumption of garlic, clove a day could be beneficial in preventing thrombosis. Prostaglandin Leukot. Essent. Fatty Acids 1995, 53:221-224.
    • (1995) Prostaglandin Leukot. Essent. Fatty Acids , vol.53 , pp. 221-224
    • Ali, M.1    Thomson, M.2
  • 3
    • 0032985666 scopus 로고    scopus 로고
    • The antihypertensive effect of garlic (Allium sativum L.) in the rat two-kidney-one-clip Goldblatt model
    • Al-Qattan K.K., Alnaqeeb M.A., Ali M. The antihypertensive effect of garlic (Allium sativum L.) in the rat two-kidney-one-clip Goldblatt model. J. Ethnopharmacol. 1999, 66:217-222.
    • (1999) J. Ethnopharmacol. , vol.66 , pp. 217-222
    • Al-Qattan, K.K.1    Alnaqeeb, M.A.2    Ali, M.3
  • 4
    • 0025893232 scopus 로고
    • Direct relaxant effects of garlic juice on smooth and cardiac muscles
    • Aqel M.B., Gharaibah M.N., Salhab A.S. Direct relaxant effects of garlic juice on smooth and cardiac muscles. J. Ethnopharmacol. 1991, 33:13-19.
    • (1991) J. Ethnopharmacol. , vol.33 , pp. 13-19
    • Aqel, M.B.1    Gharaibah, M.N.2    Salhab, A.S.3
  • 5
    • 53749100458 scopus 로고    scopus 로고
    • Pharmacodynamic interaction of garlic with captopril in ischemia-reperfusion induced myocardial damage in rats
    • Asdaq S.M., Inamdar M.N. Pharmacodynamic interaction of garlic with captopril in ischemia-reperfusion induced myocardial damage in rats. Pharmacologyonline 2008, 2:875-888.
    • (2008) Pharmacologyonline , vol.2 , pp. 875-888
    • Asdaq, S.M.1    Inamdar, M.N.2
  • 6
    • 70349202032 scopus 로고    scopus 로고
    • The potential for interaction of hydrochlorothiazide with garlic in rats
    • Asdaq S.M., Inamdar M.N. The potential for interaction of hydrochlorothiazide with garlic in rats. Chem. Biol. Interact. 2009, 181:472-479.
    • (2009) Chem. Biol. Interact. , vol.181 , pp. 472-479
    • Asdaq, S.M.1    Inamdar, M.N.2
  • 7
    • 73249136030 scopus 로고    scopus 로고
    • Pharmacodynamic interaction of garlic with hydrochlorothiazide in rats
    • Asdaq S.M., Inamdar M.N. Pharmacodynamic interaction of garlic with hydrochlorothiazide in rats. Indian J. Physiol. Pharmacol. 2009, 53:127-136.
    • (2009) Indian J. Physiol. Pharmacol. , vol.53 , pp. 127-136
    • Asdaq, S.M.1    Inamdar, M.N.2
  • 8
    • 77952046434 scopus 로고    scopus 로고
    • Pharmacodynamic interaction of captopril with garlic in isoproterenol induced myocardial damage in rat
    • Asdaq S.M., Inamdar M.N. Pharmacodynamic interaction of captopril with garlic in isoproterenol induced myocardial damage in rat. Phytother. Res. 2010, 24:720-725.
    • (2010) Phytother. Res. , vol.24 , pp. 720-725
    • Asdaq, S.M.1    Inamdar, M.N.2
  • 9
    • 63249106349 scopus 로고    scopus 로고
    • Interaction of propranolol with garlic in isoproterenol induced myocardial infarction in rat
    • Asdaq S.M., Inamdar M.N., Asad M., Nanjundan P.K. Interaction of propranolol with garlic in isoproterenol induced myocardial infarction in rat. J. Pharmacol. Toxicol. 2008, 3:414-424.
    • (2008) J. Pharmacol. Toxicol. , vol.3 , pp. 414-424
    • Asdaq, S.M.1    Inamdar, M.N.2    Asad, M.3    Nanjundan, P.K.4
  • 10
    • 0000586212 scopus 로고
    • Effect of aqueous extract of garlic on arterial blood pressure of normotensive and hypertensive rats
    • Banerjee A. Effect of aqueous extract of garlic on arterial blood pressure of normotensive and hypertensive rats. Artery 1979, 2:369-373.
    • (1979) Artery , vol.2 , pp. 369-373
    • Banerjee, A.1
  • 11
    • 2642540522 scopus 로고    scopus 로고
    • Effect of garlic on cardiovascular disorders: a review
    • Banerjee K.S., Moulik S.K. Effect of garlic on cardiovascular disorders: a review. Nutr. J. 2002, 1:1-14.
    • (2002) Nutr. J. , vol.1 , pp. 1-14
    • Banerjee, K.S.1    Moulik, S.K.2
  • 12
    • 2642588259 scopus 로고    scopus 로고
    • Chronic garlic administration protects rat heart against oxidative stress induced by ischemic-reperfusion injury
    • Banerjee S.K., Dinda A.K., Manchanda S.C., Maulik S.K. Chronic garlic administration protects rat heart against oxidative stress induced by ischemic-reperfusion injury. BMC Pharmacol. 2002, 2:16-21.
    • (2002) BMC Pharmacol. , vol.2 , pp. 16-21
    • Banerjee, S.K.1    Dinda, A.K.2    Manchanda, S.C.3    Maulik, S.K.4
  • 13
    • 0022039421 scopus 로고
    • The chemistry of garlic and onion
    • Block E. The chemistry of garlic and onion. Sci. Am. 1985, 252:114-119.
    • (1985) Sci. Am. , vol.252 , pp. 114-119
    • Block, E.1
  • 14
    • 0018143724 scopus 로고
    • Effect of garlic on human platelet aggregation in vitro
    • Bordia A. Effect of garlic on human platelet aggregation in vitro. Atherosclerosis 1978, 29:355-360.
    • (1978) Atherosclerosis , vol.29 , pp. 355-360
    • Bordia, A.1
  • 15
    • 0017740350 scopus 로고
    • Effects of essential oil of garlic on serum fibrinolytic activity in patients with coronary artery diseases
    • Bordia A., Joshi H.K., Sandhya Y.K., Bhu N. Effects of essential oil of garlic on serum fibrinolytic activity in patients with coronary artery diseases. Atherosclerosis 1978, 28:155-159.
    • (1978) Atherosclerosis , vol.28 , pp. 155-159
    • Bordia, A.1    Joshi, H.K.2    Sandhya, Y.K.3    Bhu, N.4
  • 16
    • 0017335160 scopus 로고
    • Effect of essential oil of onion and garlic on experimental atherosclerosis in rabbits
    • Bordia A., Verma S.K., Vyas A.K., Bedi H.K. Effect of essential oil of onion and garlic on experimental atherosclerosis in rabbits. Atherosclerosis 1977, 26:379-386.
    • (1977) Atherosclerosis , vol.26 , pp. 379-386
    • Bordia, A.1    Verma, S.K.2    Vyas, A.K.3    Bedi, H.K.4
  • 17
    • 0031849695 scopus 로고    scopus 로고
    • Blocking of classical complement pathway inhibits endothelial adhesion molecule expression and preserves ischemic myocardium from reperfusion injury
    • Buerke I., Prufer D., Dahm M., Oelert H., Meyer J., Darius H. Blocking of classical complement pathway inhibits endothelial adhesion molecule expression and preserves ischemic myocardium from reperfusion injury. J. Pharmacol. Exp. Ther. 1998, 286:429-438.
    • (1998) J. Pharmacol. Exp. Ther. , vol.286 , pp. 429-438
    • Buerke, I.1    Prufer, D.2    Dahm, M.3    Oelert, H.4    Meyer, J.5    Darius, H.6
  • 18
    • 33947309070 scopus 로고    scopus 로고
    • S-allylcysteine, a water-soluble garlic derivative, suppresses the growth of a human androgen-independent prostate cancer xenograft, CWR22R, under in vivo conditions
    • Chu Q., Lee D.T., Tsao S.W., Wang X., Wong Y.C. S-allylcysteine, a water-soluble garlic derivative, suppresses the growth of a human androgen-independent prostate cancer xenograft, CWR22R, under in vivo conditions. BJU Int. 2007, 99:925-932.
    • (2007) BJU Int. , vol.99 , pp. 925-932
    • Chu, Q.1    Lee, D.T.2    Tsao, S.W.3    Wang, X.4    Wong, Y.C.5
  • 19
    • 0019506366 scopus 로고
    • The effect of fried versus raw garlic on fibrinolytic activity in man
    • Chutani S.K., Bordia A. The effect of fried versus raw garlic on fibrinolytic activity in man. Atherosclerosis 1981, 38:417-421.
    • (1981) Atherosclerosis , vol.38 , pp. 417-421
    • Chutani, S.K.1    Bordia, A.2
  • 20
    • 0028958383 scopus 로고
    • Fructose-induced hypertension in rats is concentration- and duration-dependent
    • Dai S., McNeill J.H. Fructose-induced hypertension in rats is concentration- and duration-dependent. J. Pharmacol. Toxicol. Methods 1995, 33:101-107.
    • (1995) J. Pharmacol. Toxicol. Methods , vol.33 , pp. 101-107
    • Dai, S.1    McNeill, J.H.2
  • 21
    • 0028937961 scopus 로고
    • Gene expression in acute myocardial stress. Induction by hypoxia, ischemia/reperfusion, hyperthermia and oxidative stress
    • Das D.K., Maulik N., Moraru I.I. Gene expression in acute myocardial stress. Induction by hypoxia, ischemia/reperfusion, hyperthermia and oxidative stress. J. Mol. Cell. Cardiol. 1995, 27:181-193.
    • (1995) J. Mol. Cell. Cardiol. , vol.27 , pp. 181-193
    • Das, D.K.1    Maulik, N.2    Moraru, I.I.3
  • 22
    • 0034936849 scopus 로고    scopus 로고
    • Effects of the aqueous and methylene chloride extracts of bidenspilosa leaf on fructose-hypertensive rats
    • Dimo T., Azay J., Tan P.V., Pellecuer J., Cros G., Bopelet M., Serrano J.J. Effects of the aqueous and methylene chloride extracts of bidenspilosa leaf on fructose-hypertensive rats. J. Ethnopharmacol. 2001, 76:215-221.
    • (2001) J. Ethnopharmacol. , vol.76 , pp. 215-221
    • Dimo, T.1    Azay, J.2    Tan, P.V.3    Pellecuer, J.4    Cros, G.5    Bopelet, M.6    Serrano, J.J.7
  • 23
    • 0017259434 scopus 로고
    • Inhibition of nitrite formation from hydroxyl ammonium chloride. A simple assay of super oxide dismutase
    • Erich F., Elastner M. Inhibition of nitrite formation from hydroxyl ammonium chloride. A simple assay of super oxide dismutase. Anal. Chem. 1976, 70:616-620.
    • (1976) Anal. Chem. , vol.70 , pp. 616-620
    • Erich, F.1    Elastner, M.2
  • 24
    • 0023729594 scopus 로고
    • Mechanism of pH dependent hydrogen peroxide cytotoxicity in-vitro
    • Eva M.L. Mechanism of pH dependent hydrogen peroxide cytotoxicity in-vitro. Arch. Biochem. Biophys. 1988, 365:362-372.
    • (1988) Arch. Biochem. Biophys. , vol.365 , pp. 362-372
    • Eva, M.L.1
  • 26
    • 0019949179 scopus 로고
    • Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide
    • Fossati P., Prencipe L. Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin. Chem. 1982, 28:2077-2082.
    • (1982) Clin. Chem. , vol.28 , pp. 2077-2082
    • Fossati, P.1    Prencipe, L.2
  • 27
    • 0020464849 scopus 로고
    • Garlic as a natural agent for the treatment of hypertension: a preliminary report
    • Foushee D.B., Ruffin J., Banerjee U. Garlic as a natural agent for the treatment of hypertension: a preliminary report. Cytobios 1982, 34:145-152.
    • (1982) Cytobios , vol.34 , pp. 145-152
    • Foushee, D.B.1    Ruffin, J.2    Banerjee, U.3
  • 28
    • 0000817158 scopus 로고
    • Garlic chemistry: stability of S-(2-propenyl) 2-propene-1-sulfinothioate (allicin) in blood, solvents and simulated physiological fluids
    • Freeman F., Kodera Y. Garlic chemistry: stability of S-(2-propenyl) 2-propene-1-sulfinothioate (allicin) in blood, solvents and simulated physiological fluids. J Agric. Food Chem. 1995, 43:2332-2338.
    • (1995) J Agric. Food Chem. , vol.43 , pp. 2332-2338
    • Freeman, F.1    Kodera, Y.2
  • 29
    • 0023391171 scopus 로고
    • Inhibition of hepatocarcinogenic responses to 1,2-dimethylhidrazine by diallyl sulfide, a component of garlic oil
    • Hayes M., Rushman T., Goldberg M. Inhibition of hepatocarcinogenic responses to 1,2-dimethylhidrazine by diallyl sulfide, a component of garlic oil. Carcinogenesis 1987, 8:1155-1157.
    • (1987) Carcinogenesis , vol.8 , pp. 1155-1157
    • Hayes, M.1    Rushman, T.2    Goldberg, M.3
  • 31
    • 28844505085 scopus 로고    scopus 로고
    • Protective effect of s-allylcysteine and s-propyl cysteine on acetaminophen-induced hepatotoxicity in mice
    • Hsu C.C., Lin C.C., Liao T.S., Yin M.C. Protective effect of s-allylcysteine and s-propyl cysteine on acetaminophen-induced hepatotoxicity in mice. Food Chem. Toxicol. 2006, 44:393-397.
    • (2006) Food Chem. Toxicol. , vol.44 , pp. 393-397
    • Hsu, C.C.1    Lin, C.C.2    Liao, T.S.3    Yin, M.C.4
  • 32
    • 0023493524 scopus 로고
    • Fructose-induced insulin resistance and hypertension in rats
    • Hwang I.S., Ho H., Hoffman B.B., Reaven G.M. Fructose-induced insulin resistance and hypertension in rats. Hypertension 1987, 10:512-516.
    • (1987) Hypertension , vol.10 , pp. 512-516
    • Hwang, I.S.1    Ho, H.2    Hoffman, B.B.3    Reaven, G.M.4
  • 33
    • 0015536731 scopus 로고
    • Effect of S-methylcysteine sulfoxide, s-allylcysteine sulfoxide and related sulfur-containing amino acids on lipid metabolism of experimental hypercholesterolemic rats
    • Itokawa Y., Inone K., Sasagawa S., Fugiwara M. Effect of S-methylcysteine sulfoxide, s-allylcysteine sulfoxide and related sulfur-containing amino acids on lipid metabolism of experimental hypercholesterolemic rats. J. Nutr. 1973, 103:88-93.
    • (1973) J. Nutr. , vol.103 , pp. 88-93
    • Itokawa, Y.1    Inone, K.2    Sasagawa, S.3    Fugiwara, M.4
  • 35
    • 33846576597 scopus 로고    scopus 로고
    • Cardioprotective effect of grape seed proanthocyanidins on isoproterenol-induced myocardial injury in rats
    • Karthikeyan K., SaralaBai B.R., Devaraj N. Cardioprotective effect of grape seed proanthocyanidins on isoproterenol-induced myocardial injury in rats. Int. J. Cardiol. 2007, 115:326-333.
    • (2007) Int. J. Cardiol. , vol.115 , pp. 326-333
    • Karthikeyan, K.1    SaralaBai, B.R.2    Devaraj, N.3
  • 36
    • 33747840352 scopus 로고    scopus 로고
    • Dietary S-allyl-l-cysteine reduces mortality with decreased incidence of stroke and behavioral changes in strokeprone spontaneously hypertensive rats
    • Kim J.M., Chang N., Kim W.K., Chun H.S. Dietary S-allyl-l-cysteine reduces mortality with decreased incidence of stroke and behavioral changes in strokeprone spontaneously hypertensive rats. Biosci. Biotechnol. Biochem. 2006, 70:1969-1971.
    • (2006) Biosci. Biotechnol. Biochem. , vol.70 , pp. 1969-1971
    • Kim, J.M.1    Chang, N.2    Kim, W.K.3    Chun, H.S.4
  • 37
    • 33748898185 scopus 로고    scopus 로고
    • S-allyl-l-cysteine attenuates cerebral ischemic injury by scavenging peroxynitrite and inhibiting the activity of extracellular signal-regulated kinase
    • Kim J.M., Lee J.C., Chang N., Chun H.S., Kim W.K. S-allyl-l-cysteine attenuates cerebral ischemic injury by scavenging peroxynitrite and inhibiting the activity of extracellular signal-regulated kinase. Free Radic. Res. 2006, 40:827-835.
    • (2006) Free Radic. Res. , vol.40 , pp. 827-835
    • Kim, J.M.1    Lee, J.C.2    Chang, N.3    Chun, H.S.4    Kim, W.K.5
  • 38
    • 0027008725 scopus 로고
    • A comparison of antihypertensive properties of captopril and enalapril after single and multiple oral administration in spontaneously hypertensive rats
    • Kosmala M., Oledzka K., Lewandowski K., Filczewski M., Miłobedzka J. A comparison of antihypertensive properties of captopril and enalapril after single and multiple oral administration in spontaneously hypertensive rats. Pol. J. Pharmacol. Pharm. 1992, 44:437-442.
    • (1992) Pol. J. Pharmacol. Pharm. , vol.44 , pp. 437-442
    • Kosmala, M.1    Oledzka, K.2    Lewandowski, K.3    Filczewski, M.4    Miłobedzka, J.5
  • 39
    • 0346786772 scopus 로고
    • Garlic: a review of its medicinal effects and indicated active compounds. Phytomedicines of Europe: chemistry and biological activity
    • American Chemical Society, L.S. Lawson, R. Bauer (Eds.)
    • Lawson L.D. Garlic: a review of its medicinal effects and indicated active compounds. Phytomedicines of Europe: chemistry and biological activity. ACS Symposium Series, 691 1988, 176-209. American Chemical Society. L.S. Lawson, R. Bauer (Eds.).
    • (1988) ACS Symposium Series, 691 , pp. 176-209
    • Lawson, L.D.1
  • 40
    • 0018426592 scopus 로고
    • Inhibition of platelet aggregation and thromboxane synthesis by onion and garlic
    • Makheia A.N., Vanderhock J.Y., Bailey J.M. Inhibition of platelet aggregation and thromboxane synthesis by onion and garlic. Lancet 1979, 1:781-785.
    • (1979) Lancet , vol.1 , pp. 781-785
    • Makheia, A.N.1    Vanderhock, J.Y.2    Bailey, J.M.3
  • 41
    • 0020680990 scopus 로고
    • A peroxidase-coupled method for the colorimetric determination of serum triglycerides
    • Mc Gown M.W., Artiss J.D., Strandberg D.R., Zak B. A peroxidase-coupled method for the colorimetric determination of serum triglycerides. Clin. Chem. 1983, 29:538-542.
    • (1983) Clin. Chem. , vol.29 , pp. 538-542
    • Mc Gown, M.W.1    Artiss, J.D.2    Strandberg, D.R.3    Zak, B.4
  • 42
    • 0024409380 scopus 로고
    • Prevention of liver damage by aged garlic extract and its components in mice
    • Nakagawa S., Kasuga S., Matsura H. Prevention of liver damage by aged garlic extract and its components in mice. Phytother. Res. 1989, 3:50-53.
    • (1989) Phytother. Res. , vol.3 , pp. 50-53
    • Nakagawa, S.1    Kasuga, S.2    Matsura, H.3
  • 43
    • 0035123594 scopus 로고    scopus 로고
    • S-allylcysteine inhibits free radical production, lipid peroxidation and neuronal damage in rat brain ischemia
    • Numagami Y., Ohnishi S.T. S-allylcysteine inhibits free radical production, lipid peroxidation and neuronal damage in rat brain ischemia. J. Nutr. 2001, 131:1100-1105.
    • (2001) J. Nutr. , vol.131 , pp. 1100-1105
    • Numagami, Y.1    Ohnishi, S.T.2
  • 44
    • 27644581970 scopus 로고    scopus 로고
    • The effects of S-allylmercaptocaptopril, the synthetic product of allicin and captopril, on cardiovascular risk factors associated with the metabolic syndrome
    • Oron-Herman M., Rosenthal T., Mirelman D., Miron T., Rabinkov A.D., Wilchek M., Sela B. The effects of S-allylmercaptocaptopril, the synthetic product of allicin and captopril, on cardiovascular risk factors associated with the metabolic syndrome. Atherosclerosis 2005, 183:238-243.
    • (2005) Atherosclerosis , vol.183 , pp. 238-243
    • Oron-Herman, M.1    Rosenthal, T.2    Mirelman, D.3    Miron, T.4    Rabinkov, A.D.5    Wilchek, M.6    Sela, B.7
  • 45
    • 33745224775 scopus 로고    scopus 로고
    • Preventive effect of S-allylcysteine on lipid peroxides and antioxidants in normal and isoproterenol-induced cardiotoxicity in rats: a histopathological study
    • Padmanabhan M., Prince P.S. Preventive effect of S-allylcysteine on lipid peroxides and antioxidants in normal and isoproterenol-induced cardiotoxicity in rats: a histopathological study. Toxicology 2006, 224:128-137.
    • (2006) Toxicology , vol.224 , pp. 128-137
    • Padmanabhan, M.1    Prince, P.S.2
  • 46
    • 0344943236 scopus 로고    scopus 로고
    • Garlic and aging: new insights into an old remedy
    • Rahman K. Garlic and aging: new insights into an old remedy. Ageing Res. Rev. 2003, 2:39-56.
    • (2003) Ageing Res. Rev. , vol.2 , pp. 39-56
    • Rahman, K.1
  • 47
    • 0024160877 scopus 로고
    • Banting lecture 1988. Role of insulin resistance in human disease
    • Reaven G.M. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988, 37:1595-1607.
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 48
    • 38849171146 scopus 로고    scopus 로고
    • Prevention of insulin resistance by ingesting aqueous extract of Ocimum sanctum to fructose-fed rats
    • Reddy S.S., Karuna R., Baskar R., Saralakumari D. Prevention of insulin resistance by ingesting aqueous extract of Ocimum sanctum to fructose-fed rats. Horm. Metab. Res. 2008, 40:44-49.
    • (2008) Horm. Metab. Res. , vol.40 , pp. 44-49
    • Reddy, S.S.1    Karuna, R.2    Baskar, R.3    Saralakumari, D.4
  • 49
    • 0021776901 scopus 로고
    • Effects of dietary sugars in metabolic risk factors associated with heart disease
    • Reiser S. Effects of dietary sugars in metabolic risk factors associated with heart disease. Nutr. Health 1985, 3:203-216.
    • (1985) Nutr. Health , vol.3 , pp. 203-216
    • Reiser, S.1
  • 50
    • 0017801959 scopus 로고
    • SQ 14,225 (d-3-mercapto-2-methylpropanoyl-l-proline), a novel orally active inhibitor of angiotensin I-converting enzyme
    • Rubin B., Laffan R.J., Kotler D.G., O"Keefe E.H., Demaio D.A., Goldberg M.E. SQ 14,225 (d-3-mercapto-2-methylpropanoyl-l-proline), a novel orally active inhibitor of angiotensin I-converting enzyme. J. Pharmacol. Exp. Ther. 1978, 204:271-280.
    • (1978) J. Pharmacol. Exp. Ther. , vol.204 , pp. 271-280
    • Rubin, B.1    Laffan, R.J.2    Kotler, D.G.3    O"Keefe, E.H.4    Demaio, D.A.5    Goldberg, M.E.6
  • 51
    • 0020158305 scopus 로고
    • Effects of dietary garlic on temporal drift on platelet aggregation
    • Samson R.R. Effects of dietary garlic on temporal drift on platelet aggregation. Atherosclerosis 1982, 44:119-120.
    • (1982) Atherosclerosis , vol.44 , pp. 119-120
    • Samson, R.R.1
  • 52
    • 0026589474 scopus 로고
    • Statistical analysis of drug combinations for synergism
    • Tallarida R. Statistical analysis of drug combinations for synergism. Pain 1992, 49:93-97.
    • (1992) Pain , vol.49 , pp. 93-97
    • Tallarida, R.1
  • 54
    • 0024470479 scopus 로고
    • A statistical analysis of drug-drug and site-site interaction with isobolograms
    • Tallarida R., Porreca F., Cowan A. A statistical analysis of drug-drug and site-site interaction with isobolograms. Life Sci. 1989, 45:947-961.
    • (1989) Life Sci. , vol.45 , pp. 947-961
    • Tallarida, R.1    Porreca, F.2    Cowan, A.3
  • 55
    • 0024370286 scopus 로고
    • Fructose-induced in vivo insulin resistance and elevated plasma triglyceride levels in rats
    • Thorburn A.W., Storlein L.H., Jemkins A.B., Khouri S., Kraegen E.W. Fructose-induced in vivo insulin resistance and elevated plasma triglyceride levels in rats. Am. J. Clin. Nutr. 1989, 49:1155-1163.
    • (1989) Am. J. Clin. Nutr. , vol.49 , pp. 1155-1163
    • Thorburn, A.W.1    Storlein, L.H.2    Jemkins, A.B.3    Khouri, S.4    Kraegen, E.W.5
  • 56
    • 59849116161 scopus 로고    scopus 로고
    • Synergy research: Approaching a new generation of phytopharmaceuticals
    • Wagner H., Ulrich-Merzenich G. Synergy research: Approaching a new generation of phytopharmaceuticals. Phytomedicine 2009, 16:97-110.
    • (2009) Phytomedicine , vol.16 , pp. 97-110
    • Wagner, H.1    Ulrich-Merzenich, G.2
  • 57
    • 0026517057 scopus 로고
    • Antiproliferative effect of the garlic compound S-allylcysteine on human neuroblastoma cell in vitro
    • Welch C., Wuarin L., Sidell N. Antiproliferative effect of the garlic compound S-allylcysteine on human neuroblastoma cell in vitro. Cancer Lett. 1992, 63:A211-219.
    • (1992) Cancer Lett. , vol.63
    • Welch, C.1    Wuarin, L.2    Sidell, N.3
  • 58
    • 0022728197 scopus 로고
    • The effect of essential oil of garlic on hyperlipidemia and platelet aggregation
    • Zheziang Institute of Traditional Chinese Medicine The effect of essential oil of garlic on hyperlipidemia and platelet aggregation. J. Tradit. Chin. Med.. 1986, 6:117-120.
    • (1986) J. Tradit. Chin. Med.. , vol.6 , pp. 117-120
    • Zheziang Institute of Traditional Chinese Medicine1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.