S-allylcysteine, a water-soluble garlic derivative, suppresses the growth of a human androgen-independent prostate cancer xenograft, CWR22R, under in vivo conditions

BJU International

Volumn 99, Issue 4, 2007, Pages 925-932

  Chu, Qingjun ^a   Lee, Davy T W ^a   Tsao, Sai Wah ^a   Wang, Xianghong ^a   Wong, Yong Chuan ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Apoptosis; Invasion; Proliferation; Prostate cancer; S allylcysteine

Indexed keywords

ALPHA CATENIN; ANDROGEN; BETA CATENIN; CASPASE 3; CYCLINE; GARLIC EXTRACT; KI 67 ANTIGEN; PLAKOGLOBIN; PROSTATE SPECIFIC ANTIGEN; PROTEIN BCL 2; S ALLYLCYSTEINE; UVOMORULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER INHIBITION; CANCER INVASION; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VIVO STUDY; INHIBITION KINETICS; MALE; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROSTATE CARCINOMA; PROTEIN DEGRADATION; PROTEIN EXPRESSION; TUMOR XENOGRAFT;

ANDROGENS; ANIMALS; ANTINEOPLASTIC AGENTS; CYSTEINE; DRUG SCREENING ASSAYS, ANTITUMOR; MALE; MICE; MICE, NUDE; NEOPLASMS, HORMONE-DEPENDENT; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; TRANSPLANTATION, HETEROLOGOUS; TREATMENT OUTCOME;

EID: 33947309070     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2006.06639.x     Document Type: Article

References (36)

1. Jemal A, Murray T, Ward E et al. Cancer statistics, 2005. CA Cancer J Clin 2005; 55: 10-30
2. Hsing AW, Tsao L, Devesa SS. International trends and patterns of prostate cancer incidence and mortality. Int J Cancer 2000; 85: 60-7
3. Gu F. Changing constituents of genitourinary cancer in recent 50 years in Beijing. Chin Med J (Engl) 2003; 116: 1391-3
4. Herman-Antosiewicz A, Singh SV. Signal transduction pathways leading to cell cycle arrest and apoptosis induction in cancer cells by Allium vegetable-derived organosulfur compounds: a review. Mutat Res 2004; 555: 121-31
5. Hsing AW, Chokkalingam AP, Gao YT et al. Allium vegetables and risk of prostate cancer: a population-based study. J Natl Cancer Inst 2002; 94: 1648-51
6. Pinto JT, Qiao C, Xing J et al. Effects of garlic thioallyl derivatives on growth, glutathione concentration, and polyamine formation of human prostate carcinoma cells in culture. Am J Clin Nutr 1997; 66: 398-405
7. Thomson M, Ali M. Garlic [Allium sativum]: a review of its potential use as an anti-cancer agent. Curr Cancer Drug Targets 2003; 3: 67-81
8. Nagae S, Ushijima M, Hatono S et al. Pharmacokinetics of the garlic compound S-allylcysteine. Planta Med 1994; 60: 214-7
9. Amagase H, Petesch BL, Matsuura H, Kasuga S, Itakura Y. Intake of garlic and its bioactive components. J Nutr 2001; 131: 955S-62S
10. Imai J, Ide N, Nagae S, Moriguchi T, Matsuura N, Itakura Y. Antioxidant and radical scavenging effects of aged garlic extract and its constituents. Planta Med 1994; 60: 417-20
11. Katsuki T, Hirata K, Ishikawa H, Matsuura N, Sumi S, Itoh H. Aged garlic extract has chemopreventative effects on 1,2-dimethylhydrazine-induced colon tumors in rats. J Nutr 2006; 136 (Suppl.): 847S-851S
12. Xiao D, Choi S, Johnson DE et al. Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2. Oncogene 2004; 23: 5594-606
13. Xiao D, Singh SV. Diallyl trisulfide, a constituent of processed garlic, inactivates Akt to trigger mitochondrial translocation of BAD and caspase-mediated apoptosis in human prostate cancer cells. Carcinogenesis 2006; 27: 533-40
14. Xiao D, Pinto JT, Soh JW et al. Induction of apoptosis by the garlic-derived compound S-allylmercaptocysteine (SAMC) is associated with microtubule depolymerization and c-Jun NH(2)-terminal kinase 1 activation. Cancer Res 2003; 63: 6825-37
15. Xiao D, Pinto JT, Gundersen GG, Weinstein IB. Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells. Mol Cancer Ther 2005; 4: 1388-98
16. Chu Q, Ling MT, Feng H et al. A novel anticancer effect of garlic derivatives: inhibition of cancer cell invasion through restoration of E-cadherin expression. Carcinogenesis 2006; May 4: [epub ahead of print]
17. Nagabhushan M, Miller CM, Pretlow TP et al. CWR22: the first human prostate cancer xenograft with strongly androgen-dependent and relapsed strains both in vivo and in soft agar. Cancer Res 1996; 56: 3042-6
18. Sobel RE, Sadar MD. Cell lines used in prostate cancer research: a compendium of old and new lines - part 2. J Urol 2005; 173: 360-72
19. Gregory CW, Hamil KG, Kim D et al. Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes. Cancer Res 1998; 58: 5718-24
20. Chen CT, Gan Y, Au JL, Wientjes MG. Androgen-dependent and -independent human prostate xenograft tumors as models for drug activity evaluation. Cancer Res 1998; 58: 2777-83
21. Wainstein MA, He F, Robinson D et al. CWR22: androgen-dependent xenograft model derived from a primary human prostatic carcinoma. Cancer Res 1994; 54: 6049-52
22. Butler LM, Agus DB, Scher HI et al. Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo. Cancer Res 2000; 60: 5165-70
23. Gown AM, Willingham MC. Improved detection of apoptotic cells in archival paraffin sections: immunohistochemistry using antibodies to cleaved caspase 3. J Histochem Cytochem 2002; 50: 449-54
24. Duan WR, Garner DS, Williams SD, Funckes-Shippy CL, Spath IS, Blomme EA. Comparison of immunohistochemistry for activated caspase-3 and cleaved cytokeratin 18 with the TUNEL method for quantification of apoptosis in histological sections of PC-3 subcutaneous xenografts. J Pathol 2003; 199: 221-8
25. Aberle H, Schwartz H, Kemler R. Cadherin-catenin complex: protein interactions and their implications for cadherin function. J Cell Biochem 1996; 61: 514-23
26. Campbell RJ, Pignatelli M. Molecular histology in the study of solid tumours. Mol Pathol 2002; 55: 80-2
27. Kim J, Coetzee GA. Prostate specific antigen gene regulation by androgen receptor. J Cell Biochem 2004; 93: 233-41
28. Velmurugan B, Mani A, Nagini S. Combination of S-allylcysteine and lycopene induces apoptosis by modulating Bcl-2, Bax, Bim and caspases during experimental gastric carcinogenesis. Eur J Cancer Prev 2005; 14: 387-93
29. Balasenthil S, Nagini S. Inhibition of 7,12-dimethylbenz[a] anthracene-induced hamster buccal pouch carcinogenesis by S-allylcysteine. Oral Oncol 2000; 36: 382-6
30. Kodera Y, Suzuki A, Imada O et al. Physical, chemical, and biological properties of s-allylcysteine, an amino acid derived from garlic. J Agric Food Chem 2002; 50: 622-32
31. Mostafa MG, Mima T, Ohnishi ST, Mori K. S-allylcysteine ameliorates doxorubicin toxicity in the heart and liver in mice. Planta Med 2000; 66: 148-51
32. Martin KR. Targeting apoptosis with dietary bioactive agents. Exp Biol Med (Maywood) 2006; 231: 117-29
33. Philchenkov A. Caspases: potential targets for regulating cell death. J Cell Mol Med 2004; 8: 432-44
34. Wu X, Kassie F, Mersch-Sundermann V. Induction of apoptosis in tumor cells by naturally occurring sulfur-containing compounds. Mutat Res 2005; 589: 81-102
35. Morita N, Uemura H, Tsumatani K et al. E-cadherin and α-, β- and γ-catenin expression in prostate cancers: correlation with tumour invasion. Br J Cancer 1999; 79: 1879-83
36. Umbas R, Isaacs WB, Bringuier PP, Xue Y, Debruyne FM, Schalken JA. Relation between aberrant α-catenin expression and loss of E-cadherin function in prostate cancer. Int J Cancer 1997; 74: 374-7