Poor early growth and excessive adult calorie intake independently and additively affect mitogenic signaling and increase mammary tumor susceptibility

Carcinogenesis

Volumn 31, Issue 10, 2010, Pages 1873-1881

  Fernandez Twinn, D S ^a   Ekizoglou, S ^a   Martin Gronert, M S ^a   Tarry Adkins, J ^a   Wayman, A P ^a   Warner, M J ^a   Luan, J A ^b   Gusterson, B A ^c   Ozanne, S E ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1A; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GELATINASE B; GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; P21 ACTIVATED KINASE; PROGESTERONE RECEPTOR; PROTEIN KINASE B; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BODY GROWTH; BREAST TUMOR; CALORIC INTAKE; CANCER RISK; CANCER SUSCEPTIBILITY; CELL CYCLE; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; FEEDING; FEMALE; GENE EXPRESSION; INSULIN BLOOD LEVEL; MALE; MATERNAL NUTRITION; METASTASIS; MITOGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; NUTRITION; PRIORITY JOURNAL; PROTEIN RESTRICTION; PUBERTY; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRIACYLGLYCEROL BLOOD LEVEL; TUMOR SUPPRESSOR GENE; UPREGULATION;

ANIMALS; BODY WEIGHT; DISEASE SUSCEPTIBILITY; ENERGY INTAKE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION PROFILING; GROWTH DISORDERS; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, ANIMAL; RATS; RATS, WISTAR; RECEPTOR, ERBB-2; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR;

EID: 77957796759     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgq095     Document Type: Article

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