KST5468, a new T-type calcium channel antagonist, has an antinociceptive effect on inflammatory and neuropathic pain models

Pharmacology Biochemistry and Behavior

Volumn 97, Issue 2, 2010, Pages 198-204

  Lee, Min Ju ^a   Shin, Teo Jeon ^a   Lee, Jie Eun ^b,c   Choo, Hyunah ^b   Koh, Hun Yeong ^c   Chung, Hye Jin ^b   Pae, Ae Nim ^b   Lee, Sang Chul ^a   Kim, Hyun Jeong ^a  

^a Seoul National University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Inha University   (South Korea)

Author keywords

Formalin test; Hot plate test; Low voltage activated T type Ca2+ channel; Mice; Neuropathy; Pain

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL T TYPE; FORMALDEHYDE; KST 5468; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN C FOS; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; HOT PLATE TEST; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LATENT PERIOD; MALE; MOUSE; NERVE COMPRESSION; NERVE INJURY; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; SPINAL CORD DORSAL HORN;

ANALGESICS; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, T-TYPE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FORMALDEHYDE; GENE EXPRESSION; GENES, FOS; HOT TEMPERATURE; INFLAMMATION; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENOUS; ISOXAZOLES; MALE; MICE; MICE, INBRED ICR; NEURALGIA; PAIN MEASUREMENT; PIPERAZINES; POSTURAL BALANCE; REACTION TIME;

MUS;

EID: 77957786448     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2010.07.018     Document Type: Article

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