Growth Hormone (GH)-dependent expression of a natural antisense transcript induces zinc finger E-box-binding homeobox 2 (ZEB2) in the glomerular podocyte: A novel action of GH with implications for the pathogenesis of diabetic nephropathy

Journal of Biological Chemistry

Volumn 285, Issue 41, 2010, Pages 31148-31156

  Kumar, P Anil ^a   Kotlyarevska, Kateryna ^a,c   Dejkhmaron, Prapai ^a,d   Reddy, Gaddameedi R ^a,e   Lu, Chunxia ^a   Bhojani, Mahaveer S ^a   Menon, Ram K ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c Chiang Mai University ^*  (United States)

^d Faculty of Medicine Chiang Mai University   (Thailand)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE; CADHERINS; DIABETIC NEPHROPATHY; E-CADHERIN EXPRESSION; E-CADHERINS; EPITHELIAL-MESENCHYMAL TRANSITION; FUNCTIONAL CHANGES; GROWTH HORMONES; MICROALBUMINURIA; MOLECULAR BASIS; PODOCYTES; PROMOTER ACTIVITIES; QUANTITATIVE PCR; SERUM PROTEINS; TIME-DEPENDENT; ZINC FINGER;

BINDING ENERGY; BIOCHEMISTRY; ZINC;

BINDING SITES;

ALBUMIN; GROWTH HORMONE; HOMEODOMAIN PROTEIN; P CADHERIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; UVOMORULIN; ZINC FINGER E BOX BINDING HOMEOBOX 2 PROTEIN; CADHERIN; COMPLEMENTARY RNA; HUMAN GROWTH HORMONE; REPRESSOR PROTEIN; ZEB2 PROTEIN, HUMAN; ZFHX1B PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL DAMAGE; CELL IMMORTALIZATION; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE ACTIVITY; GENETIC TRANSCRIPTION; HORMONE ACTION; HUMAN; HUMAN CELL; MICROALBUMINURIA; MOUSE; NONHUMAN; PATHOGENESIS; PODOCYTE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN TARGETING; TRANSCRIPTION REGULATION; UPREGULATION; ALBUMINURIA; ANIMAL; BIOSYNTHESIS; DNA RESPONSIVE ELEMENT; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEPG2 CELL LINE; METABOLISM; PATHOLOGY; PROTEIN SYNTHESIS;

ALBUMINURIA; ANIMALS; CADHERINS; DIABETIC NEPHROPATHIES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HEP G2 CELLS; HOMEODOMAIN PROTEINS; HUMAN GROWTH HORMONE; HUMANS; MICE; PODOCYTES; PROTEIN BIOSYNTHESIS; REPRESSOR PROTEINS; RESPONSE ELEMENTS; RNA, ANTISENSE; TRANSCRIPTION, GENETIC;

EID: 77957759709     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.132332     Document Type: Article

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