Modulation of estrogen receptors during development inhibits neurogenesis of precursors to GnRH-1 neurones: In vitro studies with explants of ovine olfactory placode

Brain Research

Volumn 1223, Issue , 2008, Pages 34-41

  Agça, Esma ^a   Batailler, Martine ^a   Tillet, Yves ^a   Chemineau, Philippe ^a   Duittoz, Anne H ^a  

^a UNIVERSITÉ DE TOURS   (France)

Author keywords

Estradiol; GnRH 1; Neurogenesis; Neurons

Indexed keywords

17ALPHA ESTRADIOL; ANTIESTROGEN; ESTRADIOL; ESTROGEN RECEPTOR; GONADORELIN; GONADOTROPIN RELEASING HORMONE 1; HORMONE RECEPTOR BLOCKING AGENT; HORMONE RECEPTOR STIMULATING AGENT; TAMOXIFEN; THYMIDINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; EMBRYO; EMBRYO CULTURE; EWE; EXPLANT; FEMALE; GESTATIONAL AGE; HORMONE RELEASE; IMAGE ANALYSIS; IN VITRO STUDY; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE CELL NETWORK; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OLFACTORY SYSTEM; PRIORITY JOURNAL;

ANIMALS; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; ESTRADIOL; ESTROGEN ANTAGONISTS; FEMALE; GONADOTROPIN-RELEASING HORMONE; MATERNAL-FETAL EXCHANGE; NERVE NET; NEURONS; OLFACTORY MUCOSA; OLFACTORY PATHWAYS; PREGNANCY; PREOPTIC AREA; PROTEIN PRECURSORS; RECEPTORS, ESTROGEN; SHEEP, DOMESTIC; STEM CELLS; TAMOXIFEN;

OVIS; OVIS ARIES;

EID: 47749128429     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.05.026     Document Type: Article

References (64)

1. Audesirk T., Cabell L., Kern M., and Audesirk G. beta-estradiol influences differentiation of hippocampal neurons in vitro through an estrogen receptor-mediated process. Neuroscience 121 (2003) 927-934
2. Azcoitia I., Sierra A., and Garcia-Segura L.M. Neuroprotective effects of estradiol in the adult rat hippocampus: interaction with insulin-like growth factor-I signaling. J. Neurosci. Res. 58 (1999) 815-822
3. Banasr M., Hery M., Brezun J.M., and Daszuta A. Serotonin mediates estrogen stimulation of cell proliferation in the adult denate gyrus. Eur. J. Neurosci. 14 (2001) 1417-1424
4. Batailler M., Caraty A., Malpaux B., and Tillet Y. Neuroanatomical organization of gonadotropin-releasing hormone neurons during the oestrus cycle in the ewe. BMC Neurosci. 5 (2004) 46-46 5
5. Bean R., Seckl J.R., Lathe R., and Martin C. Ontogeny of the neurosteroid enzyme Cyp7b in the mouse. Mol. Cell. Endocrinol. 174 (2001) 137-144
6. Brannvall K., Korhonen L., and Lindholm D. Estrogen-receptor-dependent regulation of neural stem cell proliferation and differentiation. Mol. Cell. Neurosci. 21 (2002) 512-520
7. Bruneau G., Izvolskaia M., Ugrumov M., Tillet Y., and Duittoz A.H. Prolonged neurogenesis during early development of gonadotropin-releasing hormone neurones in sheep (Ovis aries): in vivo and in vitro studies. Neuroendocrinology 77 (2003) 177-186
8. Caldani M., Batailler M., J.C., T., and Dubois M.P. LHRH-immunoreactive structures in the sheep brain. Histochemistry 89 (1988) 129-139
9. Caraty A., Fabre-Nys C., Delaleu B., Locatelli A., Bruneau G., Karsch F.J., and Herbison A. Evidence that the mediobasal hypothalamus is the primary site of action of estradiol in inducing the preovulatory gonadotropin releasing hormone surge in the ewe. Endocrinology 139 (1998) 1752-1760
10. Christensen L.W., and Gorski R.A. Independent masculinization of neuroendocrine systems by intracerebral implants of testosterone or estradiol in the neonatal female rat. Brain Res. 146 (1978) 325-340
11. Clarkson J., and Herbison A.E. Development of GABA and glutamate signaling at the GnRH neuron in relation to puberty. Mol. Cell. Endocrinol. 254-255 (2006) 32-38
12. Duenas M., Torresaleman I., Naftolin F., and Garciasegura L.M. Interaction of insulin-like growth factor-I and estradiol signaling pathways on hypothalamic neuronal differentiation. Neuroscience 74 (1996) 531-539
13. Forsdike R.A., Hardy K., Bull L., Stark J., Webber L.J., Stubbs S., Robinson J.E., and Franks S. Disordered follicle development in ovaries of prenatally androgenized ewes. J. Endocrinol. 192 (2007) 421-428
14. Foster D.L., Jackson L.M., and Padmanabhan V. Programming of GnRH feedback controls timing puberty and adult reproductive activity. Mol. Cell. Endocrinol. 254-255 (2006) 109-119
15. Foster D.L., Padmanabhan V., Wood R.I., and Robinson J.E. Sexual differentiation of the neuroendocrine control of gonadotrophin secretion: concepts derived from sheep models. Reproduction 59 (2002) 83-99
16. Fueshko S., and Wray S. LHRH cells migarte on peripherin sensitive fibers in embryonic olfactory explant cultures: an in vitro model for neurophilic neuronal migration. Dev. Biol. 166 (1994) 331-348
17. Gamba M., and Pralong F.P. Control of GnRH neuronal activity by metabolic factors: the role of leptin and insulin. Mol. Cell. Endocrinol. 254-255 (2006) 133-139
18. Glidewell-Kenney C., Hurley L.A., Pfaff L., Weiss J., Levine J.E., and Jameson J.L. Nonclassical estrogen receptor alpha signaling mediates negative feedback in the female mouse reproductive axis. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 8173-8177
19. Gogan F., Slama A., Bizzini-Koutznetzova B., Dray F., and Kordon C. Importance of perinatal testosterone in sexual differentiation in the male rat. J. Endocrinol. 91 (1981) 75-79
20. Grober M.S., Winterstein G.M., Ghazanfar A.A., and Eroschenko V.P. The effects of estradiol on gonadotropin-releasing hormone neurons in the developing mouse brain. Gen. Comp. Endocrinol. 112 (1998) 356-363
21. Herbison A.E. Estrogen positive feedback to gonadotropin-releasing hormone (GnRH) neurons in the rodent: the case for the rostral periventricular area of the third ventricle (RP3V). Brain Res. Rev. 57 2 (2008) 277-287
22. Herbison A.E., and Pape J.R. New evidence for estrogen receptors in gonadotropin-releasing hormone neurons. Front. Neuroendocrinol. 22 (2001) 292-308
23. Herbosa C.G., Dahl G.E., Evans N.P., Pelt J., Wood R.I., and Foster D.L. Sexual differentiation of the surge mode of gonadotropin secretion: prenatal androgens abolish the gonadotropin-releasing hormone surge in the sheep. J. Neuroendocrinol. 8 (1996) 627-633
24. Hirst J.J., Yawno T., Nguyen P., and Walker D.W. Stress in pregnancy activates neurosteroid production in the fetal brain. Neuroendocrinology 84 (2006) 264-274
25. Hoepfner B.A., and Ward I.L. Prenatal and neonatal androgen exposure interact to affect sexual differentiation in female rats. Behav. Neurosci. 102 (1988) 61-65
26. Hoffman G.E., and Finch C.E. LHRH neurons in the female C57BL/6J mouse brain during reproductive aging: no loss up to middle age. Neurobiol. Aging 7 (1986) 45-48
27. Jacobi J.S., Martin C., Nava G., Jeziorski M.C., Clapp C., and Martinez de la Escalera G. 17-Beta-estradiol directly regulates the expression of adrenergic receptors and kisspeptin/GPR54 system in GT1-7 GnRH neurons. Neuroendocrinology 86 (2007) 260-269
28. Kuiper G.G., Enmark E., Pelto-Huikko M., Nilsson S., and Gustavsson J.A. Cloning of a novel receptor expressed in rat prostate and ovary. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 5925-5920
29. Kuiper G.G.J.M., Shughrue P.J., Merchenthaler I., and Gustafsson J.A. The estrogen receptor beta subtype: a novel mediator of estrogen action in neuroendocrine systems. Front. Neuroendocrinol. 19 (1998) 253-286
30. Mulrenin E.M., Witkin J.W., and Silverman A.J. Embryonic development of the gonadotropin-releasing hormone (GnRH) system in the chick: a spatio-temporal analysis of GnRH neuronal generation, site of origin, and migration. Endocrinology 140 (1999) 422-433
31. Murashov A.K., Pak E.S., Hendricks W.A., and Tatko L.M. 17b-estradiol enhances neuronal differentiation of mouse embryonic stem cells. FEBS Lett. 569 (2004) 165-168
32. Ordog T., Chen M.D., Nishihara M., Connaughton M.A., Goldsmith J.R., and Knobil E. On the role of gonadotropin-releasing hormone (GnRH) in the operation of the GnRH pulse generator in the rhesus monkey. Neuroendocrinology 65 (1997) 307-313
33. Ordog T., Chen M.D., Nishihara M., Connaughton M.A., Goldsmith J.R., and Knobil E. On the role of gonadotropin-releasing hormone (GnRH) in the operation of the GnRH pulse generator in the rhesus monkey. Neuroendocrinology 65 (1997) 307-313
34. Perez-Martin M., Azcoitia I., Trejo J.L., Sierra A., and Garcia-Segura L.M. An antagonist of estrogen receptors blocks the induction of adult neurogenesis by insulin-like growth factor-I in the dentate gyrus of adult female rat. Eur. J. Neurosci. 18 (2003) 923-930
35. Pietras R.J., and Szego C.M. Specific binding sites for estrogens at the outer surfaces of isolated endometrial cells. Nature 265 (1977) 69-72
36. Pillon D., Caraty A., Fabre-Nys C., and Bruneau G. Short-term effect of oestradiol on neurokinin B mRNA expression in the infundibular nucleus of ewes. J. 15 (2003) 749-753
37. Pillon D., Caraty A., Fabre-Nys C., Lomet D., Cateau M., and Bruneau G. Regulation by estradiol of hypothalamic somatostatin gene expression: possible involvement of somatostatin in the control of luteinizing hormone secretion in the ewe. Biol. Reprod. 71 (2004) 38-44. Electronic publication 2004 Feb 2025
38. Prossnitz E.R., Oprea T.I., Sklar L.A., and Arterburn J.B. The ins and outs of GPR30: a transmembrane estrogen receptor. J. Steroid Biochem. Mol. Biol. 109 3-5 (2008) 350-353
39. Raz L., Khan M.M., Mahesh V.B., Vadlamudi R.K., and Brann D.W. Rapid estrogen signaling in the brain. Neurosignals 16 (2008) 140-153
40. Razandi M., Pedram A., Greene G.L., and Levin E. Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERalpha and ER beta expressed in chinese hamster ovary cells. Mol. Endocrinol. 13 (1999) 307-319
41. Robinson J.E., Forsdike R.A., and Taylor J.A. In utero exposure of female lambs to testosterone reduces the sensitivity of the gonadotropin-releasing hormone neuronal network to inhibition by progesterone. Endocrinology 140 (1999) 5797-5805
42. Rozovsky I., Wei M., Stone D.J., Zanjani H., Anderson C.P., Morgan T.E., and Finch C.E. Estradiol (E2) enhances neurite outgrowth by repressing glial fibrillary acidic protein expression and reorganizing laminin. Endocrinology 143 (2002) 636-646
43. Rune G.M., and Frotscher M. Neurosteroid synthesis in the hippocampus: role in synaptic plasticity. Neuroscience 136 (2005) 833-842
44. Sakamoto H., Mezaki Y., Shikimi H., Ukena K., and Tsutsui K. Dendritic growth and spine formation in response to estrogen in the developing Purkinje cell. Endocrinology 144 (2003) 4466-4477
45. Sasahara K., Shikimi H., Haraguchi S., Sakamoto H., Honda S., Harada N., and Tsutsui K. Mode of action and functional significance of estrogen-inducing dendritic growth, spinogenesis, and synaptogenesis in the developing Purkinje cell. J. Neurosci. 27 (2007) 7408-7417
46. Schwanzel-Fukuda M., and Pfaff D.W. Origin of luteinizing hormone-releasing hormone neurons. Nature 338 (1989) 161-164
47. Sharifi N., Reuss A.E., and Wray S. Prenatal LHRH neurons in nasal explant cultures express estrogen receptor beta transcript. Endocrinology 143 (2002) 2503-2507
48. Tanapat P., Hastings N.B., Reeves A.J., and Gould E. Estrogen stimulates a transient increase in the number of new neurons in the dentate gyrus of the adult female rat. J. Neurosci. 19 (1999) 5792-5801
49. Tena-Sempere M. GPR54 and kisspeptin in reproduction. Hum. Reprod. Update 12 (2006) 631-639
50. Toran-Allerand C.D. Estrogen and the brain: beyond ER-alpha, ER-beta, and 17beta-estradiol. Ann. N. Y. Acad. Sci. 1052 (2005) 136-144
51. Toran-Allerand C.D., Guan X., MacLusky N.J., Horvath T.L., Diano S., Singh M., Connolly Jr. E.S., Nethrapalli I.S., and Tinnikov A.A. ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury. J. Neurosci. 22 (2002) 8391-8401
52. Toran-Allerand C.D., Tinnikov A.A., Singh R.J., and Nethrapalli I.S. 17alpha-estradiol: a brain-active estrogen?. Endocrinology 146 (2005) 3843-3850
53. Unsworth W.P., Taylor J.A., and Robinson J.E. Prenatal programming of reproductive neuroendocrine function: the effect of prenatal androgens on the development of estrogen positive feedback and ovarian cycles in the ewe. Biol. Reprod. 72 (2005) 619-627
54. Wang L., Andersson S., Warner M., and Gustafsson J.A. Estrogen receptor (ER)beta knockout mice reveal a role for ERbeta in migration of cortical neurons in the developing brain. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 703-708
55. White R., Lees J.A., Needham M., Ham J., and Parker M. Structural organization and expression of the mouse estrogen receptor. Mol. Endocrinol. 1 (1987) 735-744
56. Wood R.I., Mehta V., Herbosa C.G., and Foster D.L. Prenatal testosterone differentially masculinizes tonic and surge modes of luteinizing hormone secretion in the developing sheep. Neuroendocrinology 62 (1995) 238-247
57. Wray S., and Gainer H. Effect of neonatal gonadectomy on the postnatal development of LHRH cell subtypes in male and female rats. Neuroendocrinology 45 (1987) 413-419
58. Wray S., and Gainer H. Effect of neonatal gonadectomy on the postnatal development of LHRH cell subtypes in male and female rats. Neuroendocrinology 45 (1987) 413-419
59. Wray S., Grant P., and Gainer H. Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placode. Proc. Natl. Acad. Sci. U. S. A. 86 (1989) 8132-8136
60. Wray S., Grant P., and Gainer H. Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placode. Proc. 86 (1989) 8132-8136
61. Wray S., Nieburgs A., and Elkabes S. Spatiotemporal cell expression of luteinizing hormone-releasing hormone in the prenatal mouse: evidence for an embryonic origin in the olfactory placode. Dev. Brain Res. 46 (1989) 309-318
62. Wray S., Zoeller R.T., and Gainer H. Differential effects of estrogen on luteinizing hormone-releasing hormone gene expression in slice explant cultures prepared from specific rat forebrain regions. Mol. Endocrinol. 3 (1989) 2297-1206
63. Yawno T., Yan E.B., Walker D.W., and Hirst J.J. Inhibition of neurosteroid synthesis increases asphyxia-induced brain injury in the late gestation fetal sheep. Neuroscience 146 (2007) 1726-1733
64. Zhang Y., Milatovic D., Aschner M., Feustel P.J., and Kimelberg H.K. Neuroprotection by tamoxifen in focal cerebral ischemia is not mediated by an agonist action at estrogen receptors but is associated with antioxidant activity. Exp. Neurol. 204 (2007) 819-827