Associations between amino acids and bone mineral density in men with idiopathic osteoporosis

Bone

Volumn 47, Issue 5, 2010, Pages 959-965

  Pernow, Ylva ^a,b   Thorén, Marja ^a,b   Sääf, Maria ^a,b   Fernholm, Rita ^a,b   Anderstam, Björn ^a   Hauge, Ellen M ^c   Hall, Kerstin ^a,b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Amino acids; Bone histomorphometry; Bone mineral density; Insulin like growth factor; Male osteoporosis

Indexed keywords

ALANINE; AMINO ACID; ARGININE; ASPARAGINE; CITRULLINE; GLUTAMIC ACID; GLUTAMINE; GLYCINE; HISTIDINE; HORMONE; ISOLEUCINE; LEUCINE; LYSINE; METHIONINE; PHENYLALANINE; SERINE; TAURINE; THREONINE; TRYPTOPHAN; TYROSINE; VALINE;

ADULT; AGED; AMINO ACID BLOOD LEVEL; AMINO ACID TRANSPORT; ARTICLE; BONE BIOPSY; BONE DENSITY; CLINICAL ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; FEMUR NECK; HUMAN; HUMAN TISSUE; IDIOPATHIC OSTEOPOROSIS; LUMBAR SPINE; MALE; NUTRITIONAL STATUS; OSTEOBLAST; OSTEOMETRY; PATHOGENESIS;

ADULT; AGED; AMINO ACIDS; BONE DENSITY; CASE-CONTROL STUDIES; HUMANS; INSULIN; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR I; MALE; MIDDLE AGED; OSTEOPOROSIS;

EID: 77957751550     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2010.08.017     Document Type: Article

References (39)

1. Gennari L., Bilezikian J.P. Osteoporosis in men: pathophysiology and treatment. Curr Rheumatol Rep 2007, 9:71-77.
2. Pernow Y., Hauge E.M., Linder K., Dahl E., Sääf M. Bone histomorphometry in male idiopathic osteoporosis. Calcif Tissue Int 2009, 84:430-438.
3. Pernow Y., Granberg B., Sääf M., Weidenhielm L. Osteoblast dysfunction in male idiopathic osteoporosis. Calcif Tissue Int 2006, 78:90-97.
4. Gillberg P., Johansson A.G., Ljunghall S. Decreased estradiol levels and free androgen index and elevated sex hormone-binding globulin levels in male idiopathic osteoporosis. Calcif Tissue Int 1999, 64:209-213.
5. Kurland E.S., Rosen C.J., Cosman F., McMahon D., Chan F., Shane E., Lindsay R., Dempster D., Bilezikian J.P. Insulin-like growth factor-1 in men with idiopathic osteoporosis. J Clin Endocrinol Metab 1997, 82:2799-2805.
6. Johansson A.G., Eriksen E.F., Lindh E., Langdahl B., Blum W.F., Lindahl A., Ljunggren Ö., Ljunghall S. Reduced serum levels of the growth hormone-dependent insulin-like growth factor binding protein and a negative bone balance at the level of individual remodeling units in idiopathic osteoporosis in men. J Clin Endocrinol Metab 1997, 8:2795-2798.
7. Tom A., Nair K.S. Assessment of branched- chain amino acids and potentials for biomarkers. J Nutr 2006, 136 S:324-330.
8. Conigrave A.D., Quinn S.J., Brown E.M. L-amino acid sensing by the extracellular Ca2+-sensing receptor. Proc Natl Acad Sci USA 2000, 97:4814-4819.
9. Divino Filho J.C., Hazel S.J., Furst P., Bergström J., Hall K. Glutamate concentration in plasma, erythrocytes and muscle in relation to plasma levels of insulin-like growth factor (IGF)-I, IGF binding protein-1 and insulin in patients on haemodialysis. J Endocrinol 1998, 156:519-527.
10. Fujita Y., Youshimura Y., Inoue G. Effect of low- protein diets on free amino acids in plasma of young men: effect of protein quality with maintenance or excess energy intake. J. Nutr. Sci. Vitaminol. (Tokyo) 1978, 24:297-309.
11. Polge A., Bancel E., Bellet H., et al. Plasma amino acid concentrations in elderly patients with protein energy malnutrition. Age Ageing 1997, 26:457-462.
12. Felig P., Wahren J., Rääf L. Evidence of inter-organ amino-acid transport by blood cells in humans. Proc Natl Acad Sci USA 1970, 70:1775-1779.
13. Hagenfeldt Test L. article sample title placed here. Clin Chim Acta 1980, 100:133-141.
14. Genant H.K., Grampp S., Gluer C.C., Faulkner K.G., Jergas M., Engelke K., Hagiwara S., van Kuijk C. Universal standardization for dual x-ray absorptiometry: patient and phantom cross-calibration results. J Bone Miner Res 1994, 9:1503-1514.
15. Suliman M.E., Anderstam B., Bergström J. Evidence of taurine depletion and accumulation of cysteinsulfinic acid in chronic dialysis patients. Kidney Int 1996, 50:1713-1717.
16. Fernholm R., Thoren M., Höybye C., Anderstam B., Pernow Y., Sääf M., Hall K. Amino acid profiles in adults with growth hormone (GH) deficiency before and during GH replacement theraphy. Growth Horm IGF Res 2009, 19:206-211.
17. Bang P., Wivall I.L., Eriksson U., Sara V., Hall K. Comparison of acid ethanol extraction and acid gel filtration prior to IGF-I and IGF-II radioimmunoassays: improvement of determinations in acid ethanol extracts by the use of truncated IGF-I as radioligand. Acta Endocrinol 1991, 124:620-629.
18. Hilding A., Hall K., Wivall-Helleryd I.L., Sääf M., Melin M., Thorén M. Serum levels of insulin-like growth factor I in 152 patients with growth hormone deficiency, aged 19-82years compared with those in healthy subjects. J Clin Endocrinol Metab 1999, 84:2013-2019.
19. Póvoa G., Roovete A., Hall K. Cross-reaction of somatomedin- binding protein, a radioimmuno assay developed for somatomedin-binding protein isolated from human amniotic fluid. Acta Endocrinol 1991, 124:563-570.
20. Vermeulen A., Verdonck L., Kaufman J.M. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab 1999, 84:3666-3672.
21. Rizzoli R. Nutrition: its role in bone health. Best Pract Res Clin Endocrinol Metab 2008, 22:813-829.
22. Orwell E.S., Weigel R.M., Oviatt S.K., Meier D.E., McClung M.R. Serum protein concentrations and bone mineral content in aging normal men. Am J Clin Nutr 1987, 46:614-621.
23. Whiting S.J., Boyle J.L., Thompson A., Mirwald R.L., Faulkner R.A. Dietary protein, phosphorus and potassium are beneficial to bone mineral density in adult men consuming adequate dietary calcium. J Am Coll Nutr 2002, 21:402-409.
24. Coin A., Perissinotto E., Enzi G., Zamboni M., Inelman E.M., Frigo A.C., Manzato E., Busetto L., Buja A., Sergi G. Predictors of low bone mineral density in the elderly: the role of dietary intake, nutritional status and sarcopenia. Eur J Clin Nutr 2008, 62:802-809.
25. Rudman D., Mattson D.E., Feller A.G., Cotter R., Johnson R.C. Fasting plasma amino acids in elderly men. Am J Clin Nutr 1989, 49:559-566.
26. Chan Y.C., Suzuki M., Yamamoto S. A comparison of anthropometry, biochemical variables and plasma amino acids among centenarians, elderly and young subjects. J Am College Nutr 1999, 18:358-365.
27. Palacin M., Estevez R., Bentran J., Zorzano A. Molecular biology of mammalian plasma membrane amino acid transporters. Physiol Rev 1998, 78:969-1054.
28. Hundal H.S., Taylor P.M. Amino acids transceptors: gate keepers of nutrient exchange and regulators of nutrient signalling. Am J Physiol Endocrinol Metab 2009, 296:E603-E613.
29. Saymour R.L., Ganapathy V., Mellor A.L., Munn D.H. A high-affinity, tryptophan-selective amino acid transport system in human macrophages. J Leukoc Biol 2006, 80:1320-1327.
30. Sibilia V., Pagani F., Lattuada N., Greco A., Guidobono F. Linking chronic tryptophane deficiency with impaired bone metabolism and reduced accrual in growing rats. J Cell Biochem 2009, 107:890-898.
31. Dawson-Hughes B., Harris S., Rasmussen H.M., Dallal G.E. Comparative effects of oral aromatic and branched-chain amino acids on urine calcium excretion in humans. Osteoporos Int 2007, 18:955-961.
32. Bliziotes M.M., Eshleman A.J., Zhang X.-W., Wiren K.M. Neurotransmitter action in osteoblasts: expression of a functional system for serotonin receptor activation and reuptake. Bone 2001, 29:477-486.
33. Collet C., Schiltz C., Geoffroy V., Maroteaux L., Launay J.M., de Vernejoul M.C. The serotonin 5-HT2B receptor controls bone mass via osteoblast recruitment and proliferation. FASEB J 2008, 22:418-427.
34. Gustafsson B.I., Westbroek I., Waarsing J.H., Waldum H., Sollgård E., Brunsvik A., Dimmen S., van Leeuwen J.P., Weinans H., Syversen S. Long-term serotonin administration leads to higher bone mineral density, affects bone architecture and leads to higher femoral bone stiffness in rats. J Cell Biochem 2006, 97:1283-1291.
35. Rosen C. Serotonin rising-the bone, brain, bowel connection. New Engl J Med 2009, 360:957-959.
36. Yadav V.K., Ryu J.H., Suda N., Tanaka K.F., Gingrich J.A., Schutz G., Glorieux F.H., Chiang C.Y., Zajac J.D., Insogna K.L., Mann J.J., Hen R., Ducy P., Karsenty G. Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell 2008, 135:825-837.
37. Yadav V.K., Balaji S., Suresh P.S., Liu X.S., Lu X., Li Z., Guo X.E., Mann J.J., Balapure A.K., Gershon M.D., Medhamurthy R., Vidal M., Karsenty G., Ducy P. Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis. Nat Med Mar 2010, 16(3):308-312. Epub 2010 Feb 7.
38. Conigrave A.D., Brown E.M., Rizzoli R. Dietary protein and bone health: roles of amino acids-sensing receptors in control of calcium metabolism and bone homeostasis. Annu Rev Nutr 2008, 28:131-155.
39. Fernstrom J.D., Wurtman R.J., Hammarstrom-Wiklund B., Rand W.M., Munro H.N., Davidson C.S. Diurnal variations in plasma concentrations of tryptophan, tyrosine, and other neutral amino acids: effect of dietary protein intake. Am J Clin Nutr 1979, 32:1912-1922.