Ibrolipim increases ABCA1/G1 expression by the LXRα signaling pathway in THP-1 macrophage-derived foam cells

Acta Pharmacologica Sinica

Volumn 31, Issue 10, 2010, Pages 1343-1349

  Chen, Si Guo ^a,b   Xiao, Ji ^a   Liu, Xie Hong ^a   Liu, Mei Mei ^a   Mo, Zhong Cheng ^a   Yin, Kai ^a   Zhao, Guo Jun ^a   Jiang, Jin ^a   Cui, Li Bao ^a   Tan, Chun Zhi ^a   Yin, Wei Dong ^a   Tang, Chao Ke ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

^b XIANGNAN UNIVERSITY   (China)

Author keywords

apolipoprotein; atherosclerosis; ATP binding membrane cassette transporter A 1; ATP binding membrane cassette transporter G 1; cholesterol; high density lipoprotein; ibrolipim; liver X receptor ; RNA interference

Indexed keywords

[4 (4 BROMO 2 CYANO PHENYLCARBAMOYL) BENZYL] PHOSPHONIC ACID DIETHYL ESTER; ABC TRANSPORTER A1; ABC TRANSPORTER G1; APOLIPOPROTEIN A1; CARDIOVASCULAR AGENT; CHOLESTEROL; IBROLIPIM; LIVER X RECEPTOR ALPHA; MESSENGER RNA; OXIDIZED LOW DENSITY LIPOPROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DRUG MECHANISM; FOAM CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MACROPHAGE; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ATP-BINDING CASSETTE TRANSPORTERS; BENZAMIDES; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CELL PROLIFERATION; CHOLESTEROL; FOAM CELLS; GENE EXPRESSION REGULATION; HUMANS; LIPOPROTEIN LIPASE ACTIVATORS; ORGANOPHOSPHORUS COMPOUNDS; ORPHAN NUCLEAR RECEPTORS; RNA, MESSENGER; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 77957738702     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.166     Document Type: Article

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