메뉴 건너뛰기




Volumn 26, Issue 5, 2010, Pages 421-434

Transcriptional and posttranscriptional regulation of CYP1A1 by vanadium in human hepatoma HepG2 cells

Author keywords

Aryl hydrocarbon receptor; Carcinogenesis; Cytochrome P450 1A1; Vanadium

Indexed keywords

AMMONIUM VANADATE; CYTOCHROME P450 1A1; MESSENGER RNA; VANADIUM;

EID: 77957713088     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10565-010-9153-7     Document Type: Article
Times cited : (17)

References (58)
  • 1
    • 0028850146 scopus 로고
    • Developmental expression of two members of a new class of transcription factors: II. Expression of aryl hydrocarbon receptor nuclear translocator in the C57BL/6 N mouse embryo
    • 1:CAS:528:DyaK2MXpsVCksrs%3D 8589438
    • BD Abbott MR Probst 1995 Developmental expression of two members of a new class of transcription factors: II. Expression of aryl hydrocarbon receptor nuclear translocator in the C57BL/6 N mouse embryo Dev. Dyn. 204 144 155 1:CAS:528:DyaK2MXpsVCksrs%3D 8589438
    • (1995) Dev. Dyn. , vol.204 , pp. 144-155
    • Abbott, B.D.1    Probst, M.R.2
  • 2
    • 0028802449 scopus 로고
    • Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6 N mouse embryo
    • 1:CAS:528:DyaK2MXpsVCksro%3D 8589437
    • BD Abbott LS Birnbaum GH Perdew 1995 Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6 N mouse embryo Dev. Dyn. 204 133 143 1:CAS:528:DyaK2MXpsVCksro%3D 8589437
    • (1995) Dev. Dyn. , vol.204 , pp. 133-143
    • Abbott, B.D.1    Birnbaum, L.S.2    Perdew, G.H.3
  • 3
    • 50049101710 scopus 로고    scopus 로고
    • Down-regulation of the carcinogen-metabolizing enzyme cytochrome P450 1a1 by vanadium
    • 1:CAS:528:DC%2BD1cXhtVymu7rL 10.1124/dmd.108.021154 18541696
    • A Anwar-Mohamed AO El-Kadi 2008 Down-regulation of the carcinogen-metabolizing enzyme cytochrome P450 1a1 by vanadium Drug Metab. Dispos. 36 1819 1827 1:CAS:528:DC%2BD1cXhtVymu7rL 10.1124/dmd.108.021154 18541696
    • (2008) Drug Metab. Dispos. , vol.36 , pp. 1819-1827
    • Anwar-Mohamed, A.1    El-Kadi, A.O.2
  • 4
    • 63649090032 scopus 로고    scopus 로고
    • Down-regulation of the detoxifying enzyme NAD(P)H:quinone oxidoreductase 1 by vanadium in Hepa 1c1c7 cells
    • 1:CAS:528:DC%2BD1MXksVartbw%3D 10.1016/j.taap.2009.02.002 19367690
    • A Anwar-Mohamed AO El-Kadi 2009 Down-regulation of the detoxifying enzyme NAD(P)H:quinone oxidoreductase 1 by vanadium in Hepa 1c1c7 cells Toxicol. Appl. Pharmacol. 236 261 269 1:CAS:528:DC%2BD1MXksVartbw%3D 10.1016/j.taap.2009.02. 002 19367690
    • (2009) Toxicol. Appl. Pharmacol. , vol.236 , pp. 261-269
    • Anwar-Mohamed, A.1    El-Kadi, A.O.2
  • 5
    • 58549090733 scopus 로고    scopus 로고
    • Sulforaphane induces CYP1A1 mRNA, protein, and catalytic activity levels via an AhR-dependent pathway in murine hepatoma Hepa 1c1c7 and human HepG2 cells
    • 1:CAS:528:DC%2BD1MXhtVeiu7o%3D 10.1016/j.canlet.2008.10.003 19013013
    • A Anwar-Mohamed AO El-Kadi 2009 Sulforaphane induces CYP1A1 mRNA, protein, and catalytic activity levels via an AhR-dependent pathway in murine hepatoma Hepa 1c1c7 and human HepG2 cells Cancer Lett. 275 93 101 1:CAS:528:DC%2BD1MXhtVeiu7o%3D 10.1016/j.canlet.2008.10.003 19013013
    • (2009) Cancer Lett. , vol.275 , pp. 93-101
    • Anwar-Mohamed, A.1    El-Kadi, A.O.2
  • 6
    • 58149293750 scopus 로고    scopus 로고
    • Vanadium detoxification: Chemical and biochemical aspects
    • 1:CAS:528:DC%2BD1cXhtFagu7fF 10.1002/cbdv.200890136 18729109
    • EJ Baran 2008 Vanadium detoxification: chemical and biochemical aspects Chem. Biodivers. 5 1475 1484 1:CAS:528:DC%2BD1cXhtFagu7fF 10.1002/cbdv.200890136 18729109
    • (2008) Chem. Biodivers. , vol.5 , pp. 1475-1484
    • Baran, E.J.1
  • 7
    • 0032974651 scopus 로고    scopus 로고
    • Vanadium
    • 1:CAS:528:DyaK1MXkt1Cktbc%3D 10.1081/CLT-100102425 10382561
    • DG Barceloux 1999 Vanadium J. Toxicol. Clin. Toxicol. 37 265 278 1:CAS:528:DyaK1MXkt1Cktbc%3D 10.1081/CLT-100102425 10382561
    • (1999) J. Toxicol. Clin. Toxicol. , vol.37 , pp. 265-278
    • Barceloux, D.G.1
  • 8
    • 14044252162 scopus 로고    scopus 로고
    • Mechanisms of arsenite-mediated decreases in benzo[k]fluoranthene-induced human cytochrome P4501A1 levels in HepG2 cells
    • 1:CAS:528:DC%2BD2MXisFSgsb8%3D 10.1124/dmd.104.002212 15576448
    • EE Bessette MJ Fasco BT Pentecost LS Kaminsky 2005 Mechanisms of arsenite-mediated decreases in benzo[k]fluoranthene-induced human cytochrome P4501A1 levels in HepG2 cells Drug Metab. Dispos. 33 312 320 1:CAS:528:DC%2BD2MXisFSgsb8%3D 10.1124/dmd.104.002212 15576448
    • (2005) Drug Metab. Dispos. , vol.33 , pp. 312-320
    • Bessette, E.E.1    Fasco, M.J.2    Pentecost, B.T.3    Kaminsky, L.S.4
  • 9
    • 0029024241 scopus 로고
    • Inhibitory effect of vanadium on rat liver carcinogenesis initiated with diethylnitrosamine and promoted by phenobarbital
    • 1:CAS:528:DyaK2MXmslCnsbg%3D 7779714
    • A Bishayee M Chatterjee 1995 Inhibitory effect of vanadium on rat liver carcinogenesis initiated with diethylnitrosamine and promoted by phenobarbital Br. J. Cancer 71 1214 1220 1:CAS:528:DyaK2MXmslCnsbg%3D 7779714
    • (1995) Br. J. Cancer , vol.71 , pp. 1214-1220
    • Bishayee, A.1    Chatterjee, M.2
  • 10
    • 15744398193 scopus 로고    scopus 로고
    • Arsenite inhibition of CYP1A1 induction by 2, 3, 7, 8-tetrachlorodibenzo- p-dioxin is independent of cell cycle arrest
    • 1:CAS:528:DC%2BD2MXjtFWmsLo%3D 10.1124/mol.104.006130 15630080
    • JA Bonzo S Chen A Galijatovic RH Tukey 2005 Arsenite inhibition of CYP1A1 induction by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin is independent of cell cycle arrest Mol. Pharmacol. 67 1247 1256 1:CAS:528:DC%2BD2MXjtFWmsLo%3D 10.1124/mol.104.006130 15630080
    • (2005) Mol. Pharmacol. , vol.67 , pp. 1247-1256
    • Bonzo, J.A.1    Chen, S.2    Galijatovic, A.3    Tukey, R.H.4
  • 11
    • 0033575238 scopus 로고    scopus 로고
    • Vanadate induction of NF-kappaB involves IkappaB kinase beta and SAPK/ERK kinase 1 in macrophages
    • 1:CAS:528:DyaK1MXks1OjsLs%3D 10.1074/jbc.274.29.20307 10400652
    • F Chen LM Demers V Vallyathan M Ding Y Lu V Castranova X Shi 1999 Vanadate induction of NF-kappaB involves IkappaB kinase beta and SAPK/ERK kinase 1 in macrophages J. Biol. Chem. 274 20307 20312 1:CAS:528:DyaK1MXks1OjsLs%3D 10.1074/jbc.274.29.20307 10400652
    • (1999) J. Biol. Chem. , vol.274 , pp. 20307-20312
    • Chen, F.1    Demers, L.M.2    Vallyathan, V.3    Ding, M.4    Lu, Y.5    Castranova, V.6    Shi, X.7
  • 12
    • 32444434763 scopus 로고    scopus 로고
    • APOBEC3F and APOBEC3G mRNA levels do not correlate with human immunodeficiency virus type 1 plasma viremia or CD4+ T-cell count
    • 1:CAS:528:DC%2BD28XhsFagsbo%3D 10.1128/JVI.80.4.2069-2072.2006 16439564
    • SJ Cho H Drechsler RC Burke MQ Arens W Powderly NO Davidson 2006 APOBEC3F and APOBEC3G mRNA levels do not correlate with human immunodeficiency virus type 1 plasma viremia or CD4+ T-cell count J. Virol. 80 2069 2072 1:CAS:528:DC%2BD28XhsFagsbo%3D 10.1128/JVI.80.4.2069-2072.2006 16439564
    • (2006) J. Virol. , vol.80 , pp. 2069-2072
    • Cho, S.J.1    Drechsler, H.2    Burke, R.C.3    Arens, M.Q.4    Powderly, W.5    Davidson, N.O.6
  • 13
    • 0038768712 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
    • 1:CAS:528:DC%2BD3sXitFWqtr8%3D 10.1146/annurev.pharmtox.43.100901.135828 12540743
    • MS Denison SR Nagy 2003 Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals Annu. Rev. Pharmacol. Toxicol. 43 309 334 1:CAS:528:DC%2BD3sXitFWqtr8%3D 10.1146/annurev.pharmtox.43. 100901.135828 12540743
    • (2003) Annu. Rev. Pharmacol. Toxicol. , vol.43 , pp. 309-334
    • Denison, M.S.1    Nagy, S.R.2
  • 14
    • 0024815810 scopus 로고
    • Vanadium transport across placenta and milk of rats to the fetus and newborn
    • 1:CAS:528:DyaK3cXptlekug%3D%3D 10.1007/BF02916615 2484412
    • J Edel E Sabbioni 1989 Vanadium transport across placenta and milk of rats to the fetus and newborn Biol. Trace Elem. Res. 22 265 275 1:CAS:528:DyaK3cXptlekug%3D%3D 10.1007/BF02916615 2484412
    • (1989) Biol. Trace Elem. Res. , vol.22 , pp. 265-275
    • Edel, J.1    Sabbioni, E.2
  • 15
    • 4444366272 scopus 로고    scopus 로고
    • Modulation of aryl hydrocarbon receptor-regulated gene expression by arsenite, cadmium, and chromium
    • 1:CAS:528:DC%2BD2cXntV2nu74%3D 10.1016/j.tox.2004.05.009 15337587
    • RH Elbekai AO El-Kadi 2004 Modulation of aryl hydrocarbon receptor-regulated gene expression by arsenite, cadmium, and chromium Toxicology 202 249 269 1:CAS:528:DC%2BD2cXntV2nu74%3D 10.1016/j.tox.2004.05.009 15337587
    • (2004) Toxicology , vol.202 , pp. 249-269
    • Elbekai, R.H.1    El-Kadi, A.O.2
  • 16
    • 34547538525 scopus 로고    scopus 로고
    • Transcriptional activation and posttranscriptional modification of Cyp1a1 by arsenite, cadmium, and chromium
    • 1:CAS:528:DC%2BD2sXosFykuro%3D 10.1016/j.toxlet.2007.05.009 17606337
    • RH Elbekai AO El-Kadi 2007 Transcriptional activation and posttranscriptional modification of Cyp1a1 by arsenite, cadmium, and chromium Toxicol. Lett. 172 106 119 1:CAS:528:DC%2BD2sXosFykuro%3D 10.1016/j.toxlet.2007. 05.009 17606337
    • (2007) Toxicol. Lett. , vol.172 , pp. 106-119
    • Elbekai, R.H.1    El-Kadi, A.O.2
  • 17
    • 0035750172 scopus 로고    scopus 로고
    • Toxic metals and oxidative stress part I: Mechanisms involved in metal-induced oxidative damage
    • 1:CAS:528:DC%2BD3MXos1ait7s%3D 10.2174/1568026013394831 11895129
    • N Ercal H Gurer-Orhan N Aykin-Burns 2001 Toxic metals and oxidative stress part I: mechanisms involved in metal-induced oxidative damage Curr. Top Med. Chem. 1 529 539 1:CAS:528:DC%2BD3MXos1ait7s%3D 10.2174/1568026013394831 11895129
    • (2001) Curr. Top Med. Chem. , vol.1 , pp. 529-539
    • Ercal, N.1    Gurer-Orhan, H.2    Aykin-Burns, N.3
  • 18
    • 0036273321 scopus 로고    scopus 로고
    • Vanadium in cancer treatment
    • 10.1016/S1040-8428(01)00221-9 12050018
    • AM Evangelou 2002 Vanadium in cancer treatment Crit. Rev. Oncol. Hematol. 42 249 265 10.1016/S1040-8428(01)00221-9 12050018
    • (2002) Crit. Rev. Oncol. Hematol. , vol.42 , pp. 249-265
    • Evangelou, A.M.1
  • 19
    • 0037200012 scopus 로고    scopus 로고
    • Vanadate-induced expression of hypoxia-inducible factor 1 alpha and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen species
    • 1:CAS:528:DC%2BD38XmslOqurY%3D 10.1074/jbc.M200082200 12070140
    • N Gao M Ding JZ Zheng Z Zhang SS Leonard KJ Liu X Shi BH Jiang 2002 Vanadate-induced expression of hypoxia-inducible factor 1 alpha and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen species J. Biol. Chem. 277 31963 31971 1:CAS:528: DC%2BD38XmslOqurY%3D 10.1074/jbc.M200082200 12070140
    • (2002) J. Biol. Chem. , vol.277 , pp. 31963-31971
    • Gao, N.1    Ding, M.2    Zheng, J.Z.3    Zhang, Z.4    Leonard, S.S.5    Liu, K.J.6    Shi, X.7    Jiang, B.H.8
  • 22
    • 0023094262 scopus 로고
    • Biphasic effect of vanadium salts on in vitro tumor colony growth
    • 1:CAS:528:DyaL2sXlsVKru7c%3D 10.1002/stem.5530050209 3106514
    • U Hanauske AR Hanauske MH Marshall VA Muggia DD Von Hoff 1987 Biphasic effect of vanadium salts on in vitro tumor colony growth Int. J. Cell. Cloning 5 170 178 1:CAS:528:DyaL2sXlsVKru7c%3D 10.1002/stem.5530050209 3106514
    • (1987) Int. J. Cell. Cloning , vol.5 , pp. 170-178
    • Hanauske, U.1    Hanauske, A.R.2    Marshall, M.H.3    Muggia, V.A.4    Von Hoff, D.D.5
  • 23
    • 0028987872 scopus 로고
    • The aryl hydrocarbon receptor complex
    • 1:CAS:528:DyaK2MXlt1Grurc%3D 10.1146/annurev.pa.35.040195.001515 7598497
    • O Hankinson 1995 The aryl hydrocarbon receptor complex Annu. Rev. Pharmacol. Toxicol. 35 307 340 1:CAS:528:DyaK2MXlt1Grurc%3D 10.1146/annurev.pa. 35.040195.001515 7598497
    • (1995) Annu. Rev. Pharmacol. Toxicol. , vol.35 , pp. 307-340
    • Hankinson, O.1
  • 24
    • 40149089234 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinases in aryl hydrocarbon receptor signaling
    • 1:CAS:528:DC%2BD1cXjtVWmtLc%3D 10.1016/j.cbi.2007.12.005 18282562
    • P Henklova R Vrzal J Ulrichova Z Dvorak 2008 Role of mitogen-activated protein kinases in aryl hydrocarbon receptor signaling Chem. Biol. Interact. 172 93 104 1:CAS:528:DC%2BD1cXjtVWmtLc%3D 10.1016/j.cbi.2007.12.005 18282562
    • (2008) Chem. Biol. Interact. , vol.172 , pp. 93-104
    • Henklova, P.1    Vrzal, R.2    Ulrichova, J.3    Dvorak, Z.4
  • 25
    • 0033623993 scopus 로고    scopus 로고
    • Vanadium-induced kappaB-dependent transcription depends upon peroxide-induced activation of the p38 mitogen-activated protein kinase
    • 1:CAS:528:DC%2BD3cXlt1agtrw%3D 10873158
    • I Jaspers JM Samet S Erzurum W Reed 2000 Vanadium-induced kappaB-dependent transcription depends upon peroxide-induced activation of the p38 mitogen-activated protein kinase Am. J. Respir. Cell Mol. Biol. 23 95 102 1:CAS:528:DC%2BD3cXlt1agtrw%3D 10873158
    • (2000) Am. J. Respir. Cell Mol. Biol. , vol.23 , pp. 95-102
    • Jaspers, I.1    Samet, J.M.2    Erzurum, S.3    Reed, W.4
  • 26
    • 4043123893 scopus 로고    scopus 로고
    • Chemopreventive effects of vanadium toward 1, 2-dimethylhydrazine-induced genotoxicity and preneoplastic lesions in rat colon
    • 1:CAS:528:DC%2BD2cXms1entLs%3D 10.1002/em.20038 15278915
    • PS Kanna CB Mahendrakumar BN Indira S Srivastawa K Kalaiselvi T Elayaraja M Chatterjee 2004 Chemopreventive effects of vanadium toward 1, 2-dimethylhydrazine-induced genotoxicity and preneoplastic lesions in rat colon Environ. Mol. Mutagen. 44 113 118 1:CAS:528:DC%2BD2cXms1entLs%3D 10.1002/em.20038 15278915
    • (2004) Environ. Mol. Mutagen. , vol.44 , pp. 113-118
    • Kanna, P.S.1    Mahendrakumar, C.B.2    Indira, B.N.3    Srivastawa, S.4    Kalaiselvi, K.5    Elayaraja, T.6    Chatterjee, M.7
  • 27
    • 34547684111 scopus 로고    scopus 로고
    • Cobaltous chloride and hypoxia inhibit aryl hydrocarbon receptor-mediated responses in breast cancer cells
    • 1:CAS:528:DC%2BD2sXovFKhtro%3D 10.1016/j.taap.2007.05.010 17599377
    • S Khan S Liu M Stoner S Safe 2007 Cobaltous chloride and hypoxia inhibit aryl hydrocarbon receptor-mediated responses in breast cancer cells Toxicol. Appl. Pharmacol. 223 28 38 1:CAS:528:DC%2BD2sXovFKhtro%3D 10.1016/j.taap.2007. 05.010 17599377
    • (2007) Toxicol. Appl. Pharmacol. , vol.223 , pp. 28-38
    • Khan, S.1    Liu, S.2    Stoner, M.3    Safe, S.4
  • 28
    • 0030588279 scopus 로고    scopus 로고
    • Differences in inducibility of CYP1A1-mRNA by benzimidazole compounds between human and mouse cells: Evidences of a human-specific signal transduction pathway for CYP1A1 induction
    • 1:CAS:528:DyaK28Xmt1Smtrs%3D 10.1006/abbi.1996.0451 8900397
    • H Kikuchi H Kato M Mizuno A Hossain S Ikawa J Miyazaki M Watanabe 1996 Differences in inducibility of CYP1A1-mRNA by benzimidazole compounds between human and mouse cells: evidences of a human-specific signal transduction pathway for CYP1A1 induction Arch. Biochem. Biophys. 334 235 240 1:CAS:528: DyaK28Xmt1Smtrs%3D 10.1006/abbi.1996.0451 8900397
    • (1996) Arch. Biochem. Biophys. , vol.334 , pp. 235-240
    • Kikuchi, H.1    Kato, H.2    Mizuno, M.3    Hossain, A.4    Ikawa, S.5    Miyazaki, J.6    Watanabe, M.7
  • 29
    • 0034059998 scopus 로고    scopus 로고
    • Inhibition of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)-stimulated Cyp1a1 promoter activity by hypoxic agents
    • 1:CAS:528:DC%2BD3cXivVGntbg%3D 10.1016/S0006-2952(00)00283-5 10799651
    • JE Kim YY Sheen 2000 Inhibition of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)-stimulated Cyp1a1 promoter activity by hypoxic agents Biochem. Pharmacol. 59 1549 1556 1:CAS:528:DC%2BD3cXivVGntbg%3D 10.1016/S0006-2952(00) 00283-5 10799651
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 1549-1556
    • Kim, J.E.1    Sheen, Y.Y.2
  • 30
    • 33745221635 scopus 로고    scopus 로고
    • Quantitative relationship of dioxin-responsive gene expression to dioxin response element in Hep3B and HepG2 human hepatocarcinoma cell lines
    • 1:CAS:528:DC%2BD28Xmt1Grsbs%3D 10.1016/j.toxlet.2006.03.007 16697128
    • WK Kim YJ In JH Kim HJ Cho JH Kim S Kang CY Lee SC Lee 2006 Quantitative relationship of dioxin-responsive gene expression to dioxin response element in Hep3B and HepG2 human hepatocarcinoma cell lines Toxicol. Lett. 165 174 181 1:CAS:528:DC%2BD28Xmt1Grsbs%3D 10.1016/j.toxlet.2006.03.007 16697128
    • (2006) Toxicol. Lett. , vol.165 , pp. 174-181
    • Kim, W.K.1    In, Y.J.2    Kim, J.H.3    Cho, H.J.4    Kim, J.H.5    Kang, S.6    Lee, C.Y.7    Lee, S.C.8
  • 31
    • 0022457418 scopus 로고
    • Mechanism of cytotoxicity of anticancer platinum drugs: Evidence that cis-diamminedichloroplatinum(II) and cis-diammine-(1, 1- cyclobutanedicarboxylato)platinum(II) differ only in the kinetics of their interaction with DNA
    • 1:CAS:528:DyaL28XitFyks70%3D 3512077
    • RJ Knox F Friedlos DA Lydall JJ Roberts 1986 Mechanism of cytotoxicity of anticancer platinum drugs: evidence that cis-diamminedichloroplatinum(II) and cis-diammine-(1, 1-cyclobutanedicarboxylato)platinum(II) differ only in the kinetics of their interaction with DNA Cancer Res. 46 1972 1979 1:CAS:528:DyaL28XitFyks70%3D 3512077
    • (1986) Cancer Res. , vol.46 , pp. 1972-1979
    • Knox, R.J.1    Friedlos, F.2    Lydall, D.A.3    Roberts, J.J.4
  • 32
    • 0023393536 scopus 로고
    • Cytostatic non-platinum metal complexes: New perspectives for the treatment of cancer?
    • 1:STN:280:DyaL1c%2FhsVantg%3D%3D 10.1007/BF00405465 3309682
    • P Kopf-Maier 1987 Cytostatic non-platinum metal complexes: new perspectives for the treatment of cancer? Naturwissenschaften 74 374 382 1:STN:280:DyaL1c%2FhsVantg%3D%3D 10.1007/BF00405465 3309682
    • (1987) Naturwissenschaften , vol.74 , pp. 374-382
    • Kopf-Maier, P.1
  • 33
    • 27644489862 scopus 로고    scopus 로고
    • Regulatory mechanisms modulating the expression of cytochrome P450 1A1 gene by heavy metals
    • 1:CAS:528:DC%2BD2MXhtVyrtbzK 10.1093/toxsci/kfi282 16093525
    • HM Korashy AO El-Kadi 2005 Regulatory mechanisms modulating the expression of cytochrome P450 1A1 gene by heavy metals Toxicol Sci. 88 39 51 1:CAS:528:DC%2BD2MXhtVyrtbzK 10.1093/toxsci/kfi282 16093525
    • (2005) Toxicol Sci. , vol.88 , pp. 39-51
    • Korashy, H.M.1    El-Kadi, A.O.2
  • 34
    • 37249014997 scopus 로고    scopus 로고
    • Modulation of TCDD-mediated induction of cytochrome P450 1A1 by mercury, lead, and copper in human HepG2 cell line
    • 1:CAS:528:DC%2BD2sXhsVOksLbJ 10.1016/j.tiv.2007.08.003 17889500
    • HM Korashy AO El-Kadi 2008 Modulation of TCDD-mediated induction of cytochrome P450 1A1 by mercury, lead, and copper in human HepG2 cell line Toxicol. In Vitro 22 154 158 1:CAS:528:DC%2BD2sXhsVOksLbJ 10.1016/j.tiv.2007.08. 003 17889500
    • (2008) Toxicol. in Vitro , vol.22 , pp. 154-158
    • Korashy, H.M.1    El-Kadi, A.O.2
  • 35
    • 73449111233 scopus 로고    scopus 로고
    • Titanium and vanadium complexes as anticancer agents
    • 1:CAS:528:DC%2BD1MXhtlShu73O 19538167
    • I Kostova 2009 Titanium and vanadium complexes as anticancer agents Anticancer Agents Med Chem 9 827 842 1:CAS:528:DC%2BD1MXhtlShu73O 19538167
    • (2009) Anticancer Agents Med Chem , vol.9 , pp. 827-842
    • Kostova, I.1
  • 36
    • 0031032327 scopus 로고    scopus 로고
    • Effects of benzimidazole derivatives on cytochrome P450 1A1 expression in a human hepatoma cell line
    • 1:CAS:528:DyaK2sXhtVOqtLo%3D 10.1080/004982597240721 9041675
    • S Krusekopf U Kleeberg AG Hildebrandt K Ruckpaul 1997 Effects of benzimidazole derivatives on cytochrome P450 1A1 expression in a human hepatoma cell line Xenobiotica 27 1 9 1:CAS:528:DyaK2sXhtVOqtLo%3D 10.1080/ 004982597240721 9041675
    • (1997) Xenobiotica , vol.27 , pp. 1-9
    • Krusekopf, S.1    Kleeberg, U.2    Hildebrandt, A.G.3    Ruckpaul, K.4
  • 37
    • 0026517435 scopus 로고
    • Assessment of biological activities of mixtures of polychlorinated dibenzo-p-dioxins (PCDDs) and their constituents in human HepG2 cells
    • 1:CAS:528:DyaK38XmtVKksLw%3D 10.1007/BF01974019 1497488
    • HP Lipp D Schrenk T Wiesmuller H Hagenmaier KW Bock 1992 Assessment of biological activities of mixtures of polychlorinated dibenzo-p-dioxins (PCDDs) and their constituents in human HepG2 cells Arch. Toxicol. 66 220 223 1:CAS:528:DyaK38XmtVKksLw%3D 10.1007/BF01974019 1497488
    • (1992) Arch. Toxicol. , vol.66 , pp. 220-223
    • Lipp, H.P.1    Schrenk, D.2    Wiesmuller, T.3    Hagenmaier, H.4    Bock, K.W.5
  • 38
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • 1:CAS:528:DC%2BD38XhtFelt7s%3D 10.1006/meth.2001.1262 11846609
    • KJ Livak TD Schmittgen 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 402 408 1:CAS:528:DC%2BD38XhtFelt7s%3D 10.1006/meth.2001.1262 11846609
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 39
    • 0027485560 scopus 로고
    • A fluorescence-based protein assay for use with a microplate reader
    • 1:CAS:528:DyaK3sXms1Gksbc%3D 10.1006/abio.1993.1504 8250247
    • A Lorenzen SW Kennedy 1993 A fluorescence-based protein assay for use with a microplate reader Anal. Biochem. 214 346 348 1:CAS:528:DyaK3sXms1Gksbc%3D 10.1006/abio.1993.1504 8250247
    • (1993) Anal. Biochem. , vol.214 , pp. 346-348
    • Lorenzen, A.1    Kennedy, S.W.2
  • 41
    • 0021745314 scopus 로고
    • Induction of immunotoxicity by polycyclic hydrocarbons: Role of the Ah locus
    • 1:CAS:528:DyaL2MXlslGgsg%3D%3D 10.1007/BF00316346 6393912
    • RA Lubet MJ Brunda D Taramelli D Dansie DW Nebert RE Kouri 1984 Induction of immunotoxicity by polycyclic hydrocarbons: role of the Ah locus Arch. Toxicol. 56 18 24 1:CAS:528:DyaL2MXlslGgsg%3D%3D 10.1007/BF00316346 6393912
    • (1984) Arch. Toxicol. , vol.56 , pp. 18-24
    • Lubet, R.A.1    Brunda, M.J.2    Taramelli, D.3    Dansie, D.4    Nebert, D.W.5    Kouri, R.E.6
  • 42
    • 0025353655 scopus 로고
    • Expression of CYP1A1 gene in patients with lung cancer: Evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas
    • 1:STN:280:DyaK3czjvFGjtQ%3D%3D 10.1093/jnci/82.16.1333 2380990
    • TL Mclemore S Adelberg MC Liu NA Mcmahon SJ Yu WC Hubbard M Czerwinski TG Wood R Storeng RA Lubet, et al. 1990 Expression of CYP1A1 gene in patients with lung cancer: evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas J. Natl. Cancer Inst. 82 1333 1339 1:STN:280:DyaK3czjvFGjtQ%3D%3D 10.1093/jnci/82.16.1333 2380990
    • (1990) J. Natl. Cancer Inst. , vol.82 , pp. 1333-1339
    • Mclemore, T.L.1    Adelberg, S.2    Liu, M.C.3    Mcmahon, N.A.4    Yu, S.J.5    Hubbard, W.C.6    Czerwinski, M.7    Wood, T.G.8    Storeng, R.9    Lubet, R.A.10
  • 43
    • 0021287515 scopus 로고
    • Mechanisms of action of vanadium
    • 1:CAS:528:DyaL2cXksFelu7c%3D 10.1146/annurev.pa.24.040184.002441 6145387
    • BR Nechay 1984 Mechanisms of action of vanadium Annu. Rev. Pharmacol. Toxicol. 24 501 524 1:CAS:528:DyaL2cXksFelu7c%3D 10.1146/annurev.pa.24.040184. 002441 6145387
    • (1984) Annu. Rev. Pharmacol. Toxicol. , vol.24 , pp. 501-524
    • Nechay, B.R.1
  • 45
    • 59149097969 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways
    • 1:CAS:528:DC%2BD1MXhs1ahtr8%3D 10.1016/j.bcp.2008.08.031 18817753
    • A Puga C Ma JL Marlowe 2009 The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways Biochem. Pharmacol. 77 713 722 1:CAS:528:DC%2BD1MXhs1ahtr8%3D 10.1016/j.bcp.2008.08.031 18817753
    • (2009) Biochem. Pharmacol. , vol.77 , pp. 713-722
    • Puga, A.1    Ma, C.2    Marlowe, J.L.3
  • 46
    • 0014691619 scopus 로고
    • Platinum compounds: A new class of potent antitumour agents
    • 1:CAS:528:DyaF1MXktVWquro%3D 10.1038/222385a0 5782119
    • B Rosenberg L Vancamp JE Trosko VH Mansour 1969 Platinum compounds: a new class of potent antitumour agents Nature 222 385 386 1:CAS:528: DyaF1MXktVWquro%3D 10.1038/222385a0 5782119
    • (1969) Nature , vol.222 , pp. 385-386
    • Rosenberg, B.1    Vancamp, L.2    Trosko, J.E.3    Mansour, V.H.4
  • 47
    • 43549095276 scopus 로고    scopus 로고
    • HO-1 underlies resistance of AML cells to TNF-induced apoptosis
    • 1:CAS:528:DC%2BD1cXktlWmt78%3D 10.1182/blood-2007-07-104042 18202225
    • SA Rushworth DJ Macewan 2008 HO-1 underlies resistance of AML cells to TNF-induced apoptosis Blood 111 3793 37801 1:CAS:528:DC%2BD1cXktlWmt78%3D 10.1182/blood-2007-07-104042 18202225
    • (2008) Blood , vol.111 , pp. 3793-37801
    • Rushworth, S.A.1    Macewan, D.J.2
  • 49
    • 0034769011 scopus 로고    scopus 로고
    • Regulation of Cyp1a1 induction by dioxin as a function of cell cycle phase
    • 1:CAS:528:DC%2BD3MXnvV2qtL0%3D 11602686
    • RP Santini S Myrand C Elferink JJ Reiners Jr 2001 Regulation of Cyp1a1 induction by dioxin as a function of cell cycle phase J. Pharmacol. Exp. Ther. 299 718 728 1:CAS:528:DC%2BD3MXnvV2qtL0%3D 11602686
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 718-728
    • Santini, R.P.1    Myrand, S.2    Elferink, C.3    Reiners Jr., J.J.4
  • 50
    • 0028958395 scopus 로고
    • Phenotypic variability in induction of P-glycoprotein mRNA by aromatic hydrocarbons in primary human hepatocytes
    • 1:CAS:528:DyaK2MXkt1agtLY%3D 10.1002/mc.2940120202 7662117
    • EG Schuetz JD Schuetz MT Thompson RA Fisher JR Madariage SC Strom 1995 Phenotypic variability in induction of P-glycoprotein mRNA by aromatic hydrocarbons in primary human hepatocytes Mol. Carcinog. 12 61 65 1:CAS:528:DyaK2MXkt1agtLY%3D 10.1002/mc.2940120202 7662117
    • (1995) Mol. Carcinog. , vol.12 , pp. 61-65
    • Schuetz, E.G.1    Schuetz, J.D.2    Thompson, M.T.3    Fisher, R.A.4    Madariage, J.R.5    Strom, S.C.6
  • 51
    • 84965851166 scopus 로고
    • Polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans: The risks to human health. A review
    • 1:CAS:528:DyaL1MXksFWksLg%3D 10.1177/096032718900800301 2663703
    • SA Skene IC Dewhurst M Greenberg 1989 Polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans: the risks to human health. A review Hum. Toxicol. 8 173 203 1:CAS:528:DyaL1MXksFWksLg%3D 10.1177/096032718900800301 2663703
    • (1989) Hum. Toxicol. , vol.8 , pp. 173-203
    • Skene, S.A.1    Dewhurst, I.C.2    Greenberg, M.3
  • 52
    • 30344485139 scopus 로고    scopus 로고
    • Expression of copper-responsive genes in HepG2 cells
    • 1:CAS:528:DC%2BD2MXht1SqurnM 10.1007/s11010-005-8286-0 16283523
    • MO Song JH Freedman 2005 Expression of copper-responsive genes in HepG2 cells Mol. Cell. Biochem. 279 141 147 1:CAS:528:DC%2BD2MXht1SqurnM 10.1007/s11010-005-8286-0 16283523
    • (2005) Mol. Cell. Biochem. , vol.279 , pp. 141-147
    • Song, M.O.1    Freedman, J.H.2
  • 53
    • 0042868451 scopus 로고    scopus 로고
    • Comparing polybrominated diphenyl ether and polychlorinated biphenyl bioaccumulation in a food web in Grand Traverse Bay, Lake Michigan
    • 1:CAS:528:DC%2BD3sXmsFGkt7k%3D 10.1007/s00244-003-0165-7 14565581
    • HM Stapleton JE Baker 2003 Comparing polybrominated diphenyl ether and polychlorinated biphenyl bioaccumulation in a food web in Grand Traverse Bay, Lake Michigan Arch. Environ. Contam. Toxicol. 45 227 234 1:CAS:528: DC%2BD3sXmsFGkt7k%3D 10.1007/s00244-003-0165-7 14565581
    • (2003) Arch. Environ. Contam. Toxicol. , vol.45 , pp. 227-234
    • Stapleton, H.M.1    Baker, J.E.2
  • 54
    • 0026024980 scopus 로고
    • Exposure to dioxins and dibenzofurans through the consumption of fish
    • 1:CAS:528:DyaK3MXltlCnsrk%3D 10.1056/NEJM199101033240102 1898530
    • BG Svensson A Nilsson M Hansson C Rappe B Akesson S Skerfving 1991 Exposure to dioxins and dibenzofurans through the consumption of fish N. Engl. J. Med. 324 8 12 1:CAS:528:DyaK3MXltlCnsrk%3D 10.1056/NEJM199101033240102 1898530
    • (1991) N. Engl. J. Med. , vol.324 , pp. 8-12
    • Svensson, B.G.1    Nilsson, A.2    Hansson, M.3    Rappe, C.4    Akesson, B.5    Skerfving, S.6
  • 55
    • 0034956876 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbon/metal mixtures: Effect on PAH induction of CYP1A1 in human HEPG2 cells
    • 1:CAS:528:DC%2BD3MXksFCntrk%3D 11408366
    • DD Vakharia N Liu R Pause M Fasco E Bessette QY Zhang LS Kaminsky 2001 Polycyclic aromatic hydrocarbon/metal mixtures: effect on PAH induction of CYP1A1 in human HEPG2 cells Drug Metab. Dispos. 29 999 1006 1:CAS:528: DC%2BD3MXksFCntrk%3D 11408366
    • (2001) Drug Metab. Dispos. , vol.29 , pp. 999-1006
    • Vakharia, D.D.1    Liu, N.2    Pause, R.3    Fasco, M.4    Bessette, E.5    Zhang, Q.Y.6    Kaminsky, L.S.7
  • 56
    • 0028005379 scopus 로고
    • Development of an in vitro model for investigating the formation of the nuclear Ah receptor complex in mouse Hepa 1c1c7 cells
    • 1:CAS:528:DyaK2MXisVyjurc%3D 10.1006/abbi.1994.1502 7986070
    • X Wang S Safe 1994 Development of an in vitro model for investigating the formation of the nuclear Ah receptor complex in mouse Hepa 1c1c7 cells Arch. Biochem. Biophys. 315 285 292 1:CAS:528:DyaK2MXisVyjurc%3D 10.1006/abbi.1994. 1502 7986070
    • (1994) Arch. Biochem. Biophys. , vol.315 , pp. 285-292
    • Wang, X.1    Safe, S.2
  • 58
    • 36148955117 scopus 로고    scopus 로고
    • Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells
    • 1:CAS:528:DC%2BD2sXhtlWrsrvN 10.1016/j.tiv.2007.05.014 17637504
    • WM Westerink WG Schoonen 2007 Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells Toxicol. In Vitro 21 1581 1591 1:CAS:528:DC%2BD2sXhtlWrsrvN 10.1016/j.tiv.2007.05.014 17637504
    • (2007) Toxicol. in Vitro , vol.21 , pp. 1581-1591
    • Westerink, W.M.1    Schoonen, W.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.