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Volumn 85, Issue 10, 2010, Pages 782-786

Iron chelation therapy for patients with sickle cell disease and iron overload

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; DEFERASIROX; DEFEROXAMINE; DEFEROXAMINE MESYLATE; FERRITIN; IRON; BENZOIC ACID DERIVATIVE; DEFERIPRONE; IRON CHELATING AGENT; PYRIDONE DERIVATIVE; TRIAZOLE DERIVATIVE; ZINC;

EID: 77957687561     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.21806     Document Type: Article
Times cited : (14)

References (68)
  • 1
    • 0035725868 scopus 로고    scopus 로고
    • Practical management of iron overload
    • Porter JB. Practical management of iron overload. Br J Haematol 2001;115:239-252.
    • (2001) Br J Haematol , vol.115 , pp. 239-252
    • Porter, J.B.1
  • 2
    • 0028059813 scopus 로고
    • Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major
    • Brittenham GM, Griffith PM, Nienhuis AW, et al. Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major. N Engl J Med 1994;331:567-573.
    • (1994) N Engl J Med , vol.331 , pp. 567-573
    • Brittenham, G.M.1    Griffith, P.M.2    Nienhuis, A.W.3
  • 3
    • 0034631379 scopus 로고    scopus 로고
    • Survival in b-thalassaemia major in the UK: Data from the UK Thalassaemia Register
    • Modell B, Khan M, Darlison M. Survival in b-thalassaemia major in the UK: Data from the UK Thalassaemia Register. Lancet 2000;355:2051-2052.
    • (2000) Lancet , vol.355 , pp. 2051-2052
    • Modell, B.1    Khan, M.2    Darlison, M.3
  • 4
    • 0017836732 scopus 로고
    • Excretion of iron in response to deferoxamine in sickle cell anemia
    • Cohen A, Schwartz E. Excretion of iron in response to deferoxamine in sickle cell anemia. J Pediatr 1978;92:659-662.
    • (1978) J Pediatr , vol.92 , pp. 659-662
    • Cohen, A.1    Schwartz, E.2
  • 5
    • 0018696370 scopus 로고
    • Iron chelation therapy in sickle cell anemia
    • Cohen A, Schwartz E. Iron chelation therapy in sickle cell anemia. Am J Hematol 1979;7:69-76.
    • (1979) Am J Hematol , vol.7 , pp. 69-76
    • Cohen, A.1    Schwartz, E.2
  • 6
    • 0024355371 scopus 로고
    • Rapid removal of excessive iron with daily, high-dose intravenous chelation therapy
    • Cohen AR, Mizanin J, Schwartz E. Rapid removal of excessive iron with daily, high-dose intravenous chelation therapy. J Pediatr 1989;115:151-155.
    • (1989) J Pediatr , vol.115 , pp. 151-155
    • Cohen, A.R.1    Mizanin, J.2    Schwartz, E.3
  • 7
    • 84925565750 scopus 로고    scopus 로고
    • Safety and efficacy of high dose intravenous desferoxamine for reduction of iron overload due to chronic transfusion in sickle cell patients
    • abst 1430
    • Kalpatthi R, Peters B, Holloman D, et al. Safety and efficacy of high dose intravenous desferoxamine for reduction of iron overload due to chronic transfusion in sickle cell patients. Blood 2008;112:abst 1430.
    • (2008) Blood , vol.112
    • Kalpatthi, R.1    Peters, B.2    Holloman, D.3
  • 8
    • 0027209895 scopus 로고
    • Iron chelation by deferoxamine in sickle cell patients with severe transfusion-induced hemosiderosis: A randomized, double-blind study of the dose-response relationship
    • Silliman CC, Peterson VM, Mellman DL, et al. Iron chelation by deferoxamine in sickle cell patients with severe transfusion-induced hemosiderosis: A randomized, double-blind study of the dose-response relationship. J Lab Clin Med 1993;122:48-54.
    • (1993) J Lab Clin Med , vol.122 , pp. 48-54
    • Silliman, C.C.1    Peterson, V.M.2    Mellman, D.L.3
  • 9
    • 0022628511 scopus 로고
    • Visual and auditory neurotoxicity in patients receiving subcutaneous deferoxamine infusions
    • Olivieri NF, Buncic JR, Chew E, et al. Visual and auditory neurotoxicity in patients receiving subcutaneous deferoxamine infusions. N Engl J Med 1986;314:869-873.
    • (1986) N Engl J Med , vol.314 , pp. 869-873
    • Olivieri, N.F.1    Buncic, J.R.2    Chew, E.3
  • 10
    • 0031917978 scopus 로고    scopus 로고
    • Plasma zinc status, growth, and maturation in children with sickle cell disease
    • Leonard MB, Zemel BS, Kawchak DA, et al. Plasma zinc status, growth, and maturation in children with sickle cell disease. J Pediatr 1998;132:467-471.
    • (1998) J Pediatr , vol.132 , pp. 467-471
    • Leonard, M.B.1    Zemel, B.S.2    Kawchak, D.A.3
  • 11
    • 14644407445 scopus 로고    scopus 로고
    • Psychosocial implications of thalassemia major
    • Aydinok Y, Erermis S, Bukusoglu N, et al. Psychosocial implications of thalassemia major. Pediatr Int 2005;47:84-89.
    • (2005) Pediatr Int , vol.47 , pp. 84-89
    • Aydinok, Y.1    Erermis, S.2    Bukusoglu, N.3
  • 12
    • 33750440169 scopus 로고    scopus 로고
    • The impact of iron overload and its treatment on quality of life: Results from a literature review
    • Abetz L, Baladi J-F, Jones P, Rofail D. The impact of iron overload and its treatment on quality of life: Results from a literature review. Health Qual Life Outcomes 2006;4:73.
    • (2006) Health Qual Life Outcomes , vol.4 , pp. 73
    • Abetz, L.1    Baladi, J.-F.2    Jones, P.3    Rofail, D.4
  • 13
    • 18144404276 scopus 로고    scopus 로고
    • Barriers to adherence of deferoxamine usage in sickle cell disease
    • Treadwell MJ, Law AW, Sung J, et al. Barriers to adherence of deferoxamine usage in sickle cell disease. Pediatr Blood Cancer 2005;44:500-507.
    • (2005) Pediatr Blood Cancer , vol.44 , pp. 500-507
    • Treadwell, M.J.1    Law, A.W.2    Sung, J.3
  • 15
    • 0037630378 scopus 로고    scopus 로고
    • Role of deferiprone in chelation therapy for transfusional iron overload
    • Hoffbrand AV, Cohen A, Hershko C. Role of deferiprone in chelation therapy for transfusional iron overload. Blood 2003;102:17-24.
    • (2003) Blood , vol.102 , pp. 17-24
    • Hoffbrand, A.V.1    Cohen, A.2    Hershko, C.3
  • 16
    • 0032514558 scopus 로고    scopus 로고
    • Long-term safety and effectiveness of iron-chelation therapy with deferiprone for thalassemia major
    • Olivieri NF, Brittenham GM, McLaren CE, et al. Long-term safety and effectiveness of iron-chelation therapy with deferiprone for thalassemia major. N Engl J Med 1998;339:417-423.
    • (1998) N Engl J Med , vol.339 , pp. 417-423
    • Olivieri, N.F.1    Brittenham, G.M.2    McLaren, C.E.3
  • 17
    • 0028345040 scopus 로고
    • Iron-balance and dose-response studies of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in iron-loaded patients with sickle cell disease
    • Collins AF, Fassos FF, Stobie S, et al. Iron-balance and dose-response studies of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in iron-loaded patients with sickle cell disease. Blood 1994;83:2329-2333.
    • (1994) Blood , vol.83 , pp. 2329-2333
    • Collins, A.F.1    Fassos, F.F.2    Stobie, S.3
  • 18
    • 0031985039 scopus 로고    scopus 로고
    • Long-term trial of deferiprone in 51 transfusion-dependent iron overloaded patients
    • Hoffbrand AV, AL Refaie F, Davis B, et al. Long-term trial of deferiprone in 51 transfusion-dependent iron overloaded patients. Blood 1998;91:295-300.
    • (1998) Blood , vol.91 , pp. 295-300
    • Hoffbrand, A.V.1    Refaie F, A.L.2    Davis, B.3
  • 19
    • 0029825581 scopus 로고    scopus 로고
    • Long-term treatment of transfusional iron overload with the oral iron chelator deferiprone (L1): A Dutch multicenter trial
    • Kersten MJ, Lange R, Smeets ME, et al. Long-term treatment of transfusional iron overload with the oral iron chelator deferiprone (L1): A Dutch multicenter trial. Ann Hematol 1996;73:247-252.
    • (1996) Ann Hematol , vol.73 , pp. 247-252
    • Kersten, M.J.1    Lange, R.2    Smeets, M.E.3
  • 20
    • 20944435298 scopus 로고    scopus 로고
    • Deferiprone as an oral iron chelator in sickle cell disease
    • Voskaridou E, Douskou M, Terpos E, et al. Deferiprone as an oral iron chelator in sickle cell disease. Ann Hematol 2005;84:434-440.
    • (2005) Ann Hematol , vol.84 , pp. 434-440
    • Voskaridou, E.1    Douskou, M.2    Terpos, E.3
  • 21
    • 0031784438 scopus 로고    scopus 로고
    • Combined therapy with deferiprone and desferrioxamine
    • Wonke B, Wright C, Hoffbrand AV. Combined therapy with deferiprone and desferrioxamine. Br J Haematol 1998;103:361-364.
    • (1998) Br J Haematol , vol.103 , pp. 361-364
    • Wonke, B.1    Wright, C.2    Hoffbrand, A.V.3
  • 22
    • 0029079707 scopus 로고
    • Results of long-term deferiprone (L1) therapy: A report by the International Study Group on Oral Iron Chelators
    • al Refaie FN, Hershko C, Hoffbrand AV, et al. Results of long-term deferiprone (L1) therapy: A report by the International Study Group on Oral Iron Chelators. Br J Haematol 1995;91:224-229.
    • (1995) Br J Haematol , vol.91 , pp. 224-229
    • Al Refaie, F.N.1    Hershko, C.2    Hoffbrand, A.V.3
  • 23
    • 33846012866 scopus 로고    scopus 로고
    • A randomized comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease
    • Vichinsky E, Onyekwere O, Porter J, et al. A randomized comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease. Br J Haematol 2007;136:501-508.
    • (2007) Br J Haematol , vol.136 , pp. 501-508
    • Vichinsky, E.1    Onyekwere, O.2    Porter, J.3
  • 24
    • 77950682176 scopus 로고    scopus 로고
    • Tailoring iron chelation by iron intake and serum ferritin trends: The prospective multicenter EPIC study of deferasirox in 1744 patients with various transfusion-dependent anemias
    • Cappellini MD, Porter JB, El-Beshlawy A, et al. Tailoring iron chelation by iron intake and serum ferritin trends: the prospective multicenter EPIC study of deferasirox in 1744 patients with various transfusion-dependent anemias. Haematologica 2010;95:557-566.
    • (2010) Haematologica , vol.95 , pp. 557-566
    • Cappellini, M.D.1    Porter, J.B.2    El-Beshlawy, A.3
  • 25
    • 42949148046 scopus 로고    scopus 로고
    • Clinical application of deferasirox: Practical patient management
    • Vichinsky E. Clinical application of deferasirox: Practical patient management. Am J Hematol 2008;83:398-402.
    • (2008) Am J Hematol , vol.83 , pp. 398-402
    • Vichinsky, E.1
  • 26
    • 77955279943 scopus 로고    scopus 로고
    • Safety of deferasirox (Exjade®) in myelodysplastic syndromes (MDS) and non-MDS patients with transfusional iron overload: A pooled analysis focusing on renal function
    • abst 1768
    • Schmid M, Cappellini MD, Porter JB, et al. Safety of deferasirox (Exjade®) in myelodysplastic syndromes (MDS) and non-MDS patients with transfusional iron overload: A pooled analysis focusing on renal function. Blood 2009;114:abst 1768.
    • (2009) Blood , vol.114
    • Schmid, M.1    Cappellini, M.D.2    Porter, J.B.3
  • 27
    • 70450136053 scopus 로고    scopus 로고
    • Deferasirox (Exjade®), the once-daily oral iron chelator, demonstrates safety and efficacy in patients with sickle cell disease (SCD): 3.5-year follow-up
    • abst 1420
    • Vichinsky E, Coates T, Thompson AA, et al. Deferasirox (Exjade®), the once-daily oral iron chelator, demonstrates safety and efficacy in patients with sickle cell disease (SCD): 3.5-year follow-up. Blood 2008;112:abst 1420.
    • (2008) Blood , vol.112
    • Vichinsky, E.1    Coates, T.2    Thompson, A.A.3
  • 28
    • 77949438662 scopus 로고    scopus 로고
    • Treatment with deferasirox effectively decreases iron burden in patients with sickle cell syndromes
    • abst 215
    • Voskaridou E, Douskou M, Plata E, et al. Treatment with deferasirox effectively decreases iron burden in patients with sickle cell syndromes. Haematologica 2009;94(Suppl 2):abst 215.
    • (2009) Haematologica , vol.94 , Issue.SUPPL. 2
    • Voskaridou, E.1    Douskou, M.2    Plata, E.3
  • 29
    • 77949475431 scopus 로고    scopus 로고
    • Deferasirox for the treatment of transfusional iron overload in sickle cell anemia: A 1-yr prospective study
    • abst 210
    • Cancado R, Olivato MC, Bruniera P, Chiattone C. Deferasirox for the treatment of transfusional iron overload in sickle cell anemia: A 1-yr prospective study. Haematologica 2009;94(Suppl 2):abst 210.
    • (2009) Haematologica , vol.94 , Issue.SUPPL. 2
    • Cancado, R.1    Olivato, M.C.2    Bruniera, P.3    Chiattone, C.4
  • 30
    • 0032474692 scopus 로고    scopus 로고
    • Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography
    • Adams RJ, McKie VC, Hsu L, et al. Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography. N Engl J Med 1998;339:5-11.
    • (1998) N Engl J Med , vol.339 , pp. 5-11
    • Adams, R.J.1    McKie, V.C.2    Hsu, L.3
  • 31
    • 29544444495 scopus 로고    scopus 로고
    • Discontinuing prophylactic transfusions used to prevent stroke in sickle cell disease
    • Adams RJ, Brambilla D. Discontinuing prophylactic transfusions used to prevent stroke in sickle cell disease. N Engl J Med 2005;353:2769-2778.
    • (2005) N Engl J Med , vol.353 , pp. 2769-2778
    • Adams, R.J.1    Brambilla, D.2
  • 32
    • 62849129028 scopus 로고    scopus 로고
    • Current issues in blood transfusion for sickle cell disease
    • Wahl S, Quirolo KC. Current issues in blood transfusion for sickle cell disease. Curr Opin Pediatr 2009;21:15-21.
    • (2009) Curr Opin Pediatr , vol.21 , pp. 15-21
    • Wahl, S.1    Quirolo, K.C.2
  • 33
    • 73949087363 scopus 로고    scopus 로고
    • Sickle cell disease and stroke
    • Verduzco LA, Nathan DG. Sickle cell disease and stroke. Blood 2009;114:5117-5125.
    • (2009) Blood , vol.114 , pp. 5117-5125
    • Verduzco, L.A.1    Nathan, D.G.2
  • 34
    • 5044239523 scopus 로고    scopus 로고
    • Sickle-cell disease
    • Stuart MJ, Nagel RL. Sickle-cell disease. Lancet 2004;364:1343-1360.
    • (2004) Lancet , vol.364 , pp. 1343-1360
    • Stuart, M.J.1    Nagel, R.L.2
  • 35
    • 0033599057 scopus 로고    scopus 로고
    • Disorders of iron metabolism
    • Andrews NC. Disorders of iron metabolism. N Engl J Med 1999;341:1986-1995.
    • (1999) N Engl J Med , vol.341 , pp. 1986-1995
    • Andrews, N.C.1
  • 36
    • 0035137382 scopus 로고    scopus 로고
    • Iron overload is a determinant of morbidity and mortality in adult patients with sickle cell disease
    • Ballas SK. Iron overload is a determinant of morbidity and mortality in adult patients with sickle cell disease. Semin Hematol 2001;38(Suppl 1):30-36.
    • (2001) Semin Hematol , vol.38 , Issue.SUPPL. 1 , pp. 30-36
    • Ballas, S.K.1
  • 37
    • 33750600143 scopus 로고    scopus 로고
    • Circumstances of death in adult sickle cell disease patients
    • Darbari DS, Kple-Faget P, Kwagyan J, et al. Circumstances of death in adult sickle cell disease patients. Am J Hematol 2006;81:858-863.
    • (2006) Am J Hematol , vol.81 , pp. 858-863
    • Darbari, D.S.1    Kple-Faget, P.2    Kwagyan, J.3
  • 38
    • 34147180552 scopus 로고    scopus 로고
    • Morbidity and mortality in chronically transfused subjects with thalassemia and sickle cell disease: A report from the multi-center study of iron overload
    • Fung EB, Harmatz P, Milet M, et al. Morbidity and mortality in chronically transfused subjects with thalassemia and sickle cell disease: A report from the multi-center study of iron overload. Am J Hematol 2007;82:255-265.
    • (2007) Am J Hematol , vol.82 , pp. 255-265
    • Fung, E.B.1    Harmatz, P.2    Milet, M.3
  • 39
    • 34347269612 scopus 로고    scopus 로고
    • Pulmonary hypertension in patients with sickle cell/beta thalassemia: Incidence and correlation with serum N-terminal pro-brain natriuretic peptide concentrations
    • Voskaridou E, Tsetsos G, Tsoutsias A, et al. Pulmonary hypertension in patients with sickle cell/beta thalassemia: Incidence and correlation with serum N-terminal pro-brain natriuretic peptide concentrations. Haematologica 2007;92:738-743.
    • (2007) Haematologica , vol.92 , pp. 738-743
    • Voskaridou, E.1    Tsetsos, G.2    Tsoutsias, A.3
  • 40
    • 76449084357 scopus 로고    scopus 로고
    • N-terminal natriuretic peptide and ventilation-perfusion lung scan in sickle cell disease and thalassemia patients with pulmonary hypertension
    • Mokhtar GM, Adly AA, El Alfy MS, et al. N-terminal natriuretic peptide and ventilation-perfusion lung scan in sickle cell disease and thalassemia patients with pulmonary hypertension. Hemoglobin 2010;34:78-94.
    • (2010) Hemoglobin , vol.34 , pp. 78-94
    • Mokhtar, G.M.1    Adly, A.A.2    El Alfy, M.S.3
  • 41
    • 0034235835 scopus 로고    scopus 로고
    • Severity of iron overload in patients with sickle cell disease receiving chronic red blood cell transfusion therapy
    • Harmatz P, Butensky E, Quirolo K, et al. Severity of iron overload in patients with sickle cell disease receiving chronic red blood cell transfusion therapy. Blood 2000;96:76-79.
    • (2000) Blood , vol.96 , pp. 76-79
    • Harmatz, P.1    Butensky, E.2    Quirolo, K.3
  • 42
    • 24344505753 scopus 로고    scopus 로고
    • Comparison of organ dysfunction in transfused patients with SCD or b thalassemia
    • Vichinsky E, Butensky E, Fung E, et al. Comparison of organ dysfunction in transfused patients with SCD or b thalassemia. Am J Hematol 2005;80:70-74.
    • (2005) Am J Hematol , vol.80 , pp. 70-74
    • Vichinsky, E.1    Butensky, E.2    Fung, E.3
  • 43
  • 44
    • 0024337363 scopus 로고
    • Survival and causes of death in thalassaemia major
    • Zurlo MG, De Stefano P, Borgna-Pignatti C, et al. Survival and causes of death in thalassaemia major. Lancet 1989;2:27-30.
    • (1989) Lancet , vol.2 , pp. 27-30
    • Zurlo, M.G.1    De Stefano, P.2    Borgna-Pignatti, C.3
  • 45
    • 70449499193 scopus 로고    scopus 로고
    • Absence of cardiac siderosis by MRI T2* despite transfusion burden, hepatic and serum iron overload in Lebanese patients with sickle cell disease
    • Inati A, Musallam KM, Wood JC, et al. Absence of cardiac siderosis by MRI T2* despite transfusion burden, hepatic and serum iron overload in Lebanese patients with sickle cell disease. Eur J Haematol 2009;83:565-571.
    • (2009) Eur J Haematol , vol.83 , pp. 565-571
    • Inati, A.1    Musallam, K.M.2    Wood, J.C.3
  • 46
    • 1442307460 scopus 로고    scopus 로고
    • Myocardial iron loading in transfusion-dependent thalassemia and sickle cell disease
    • Wood JC, Tyszka JM, Carson S, et al. Myocardial iron loading in transfusion-dependent thalassemia and sickle cell disease. Blood 2004;103:1934-1936.
    • (2004) Blood , vol.103 , pp. 1934-1936
    • Wood, J.C.1    Tyszka, J.M.2    Carson, S.3
  • 47
    • 33750049951 scopus 로고    scopus 로고
    • Increased prevalence of iron-overload associated endocrinopathy in thalassaemia versus sickle-cell disease
    • Fung EB, Harmatz PR, Lee PD, et al. Increased prevalence of iron-overload associated endocrinopathy in thalassaemia versus sickle-cell disease. Br J Haematol 2006;135:574-582.
    • (2006) Br J Haematol , vol.135 , pp. 574-582
    • Fung, E.B.1    Harmatz, P.R.2    Lee, P.D.3
  • 48
    • 0024348472 scopus 로고
    • Model of reticuloendothelial iron metabolism in humans: Abnormal behavior in idiopathic hemochromatosis and in inflammation
    • Fillet G, Beguin Y, Baldelli L. Model of reticuloendothelial iron metabolism in humans: Abnormal behavior in idiopathic hemochromatosis and in inflammation. Blood 1989;74:844-851.
    • (1989) Blood , vol.74 , pp. 844-851
    • Fillet, G.1    Beguin, Y.2    Baldelli, L.3
  • 49
    • 33748749961 scopus 로고    scopus 로고
    • Oxidative stress and inflammation in iron-overloaded patients with beta-thalassaemia or sickle cell disease
    • Walter PB, Fung EB, Killilea DW, et al. Oxidative stress and inflammation in iron-overloaded patients with beta-thalassaemia or sickle cell disease. Br J Haematol 2006;135:254-263.
    • (2006) Br J Haematol , vol.135 , pp. 254-263
    • Walter, P.B.1    Fung, E.B.2    Killilea, D.W.3
  • 50
    • 72449151347 scopus 로고    scopus 로고
    • Non transferrin bound labile plasma iron and iron overload in sickle cell disease: A comparative study between sickle cell disease and beta thalassemic patients
    • Koren A, Fink D, Admoni O, et al. Non transferrin bound labile plasma iron and iron overload in sickle cell disease: A comparative study between sickle cell disease and beta thalassemic patients. Eur J Haematol 2010;84:72-78.
    • (2010) Eur J Haematol , vol.84 , pp. 72-78
    • Koren, A.1    Fink, D.2    Admoni, O.3
  • 51
    • 0013409935 scopus 로고    scopus 로고
    • NIH Publication No 02-2117. Available at
    • The management of sickle cell disease. NIH Publication No 02-2117. 2002. Available at:http://www.nhlbi.nih.gov/health/prof/blood/sickle/sc-mngt.pdf.
    • (2002) The Management of Sickle Cell Disease
  • 53
    • 33646414765 scopus 로고    scopus 로고
    • A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with b-thalassemia
    • Cappellini MD, Cohen A, Piga A, et al. A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with b-thalassemia. Blood 2006;107:3455-3462.
    • (2006) Blood , vol.107 , pp. 3455-3462
    • Cappellini, M.D.1    Cohen, A.2    Piga, A.3
  • 54
    • 0028898064 scopus 로고
    • Iron-chelation therapy with oral deferiprone in patients with thalassemia major
    • Olivieri NF, Brittenham GM, Matsui D, et al. Iron-chelation therapy with oral deferiprone in patients with thalassemia major. N Engl J Med 1995;332:918-922.
    • (1995) N Engl J Med , vol.332 , pp. 918-922
    • Olivieri, N.F.1    Brittenham, G.M.2    Matsui, D.3
  • 55
    • 38049151217 scopus 로고    scopus 로고
    • Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): A 1-yr prospective study
    • Porter J, Galanello R, Saglio G, et al. Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): A 1-yr prospective study. Eur J Haematol 2008;80: 168-176.
    • (2008) Eur J Haematol , vol.80 , pp. 168-176
    • Porter, J.1    Galanello, R.2    Saglio, G.3
  • 56
    • 0023613154 scopus 로고
    • Transfusion and exchange transfusion in sickle cell anaemias, with particular reference to iron metabolism
    • Porter JB, Huehns ER. Transfusion and exchange transfusion in sickle cell anaemias, with particular reference to iron metabolism. Acta Haematol 1987;78:198-205.
    • (1987) Acta Haematol , vol.78 , pp. 198-205
    • Porter, J.B.1    Huehns, E.R.2
  • 57
    • 0027463317 scopus 로고
    • Hepatic iron stores and plasma ferritin concentration in patients with sickle cell anemia and thalassemia major
    • Brittenham GM, Cohen AR, McLaren CE, et al. Hepatic iron stores and plasma ferritin concentration in patients with sickle cell anemia and thalassemia major. Am J Hematol 1993;42:81-85.
    • (1993) Am J Hematol , vol.42 , pp. 81-85
    • Brittenham, G.M.1    Cohen, A.R.2    McLaren, C.E.3
  • 58
    • 36849004367 scopus 로고    scopus 로고
    • Liver biopsy results in patients with sickle cell disease on chronic transfusions: Poor correlation with ferritin levels
    • Karam LB, Disco D, Jackson SM, et al. Liver biopsy results in patients with sickle cell disease on chronic transfusions: Poor correlation with ferritin levels. Pediatr Blood Cancer 2008;50:62-65.
    • (2008) Pediatr Blood Cancer , vol.50 , pp. 62-65
    • Karam, L.B.1    Disco, D.2    Jackson, S.M.3
  • 59
    • 77957684867 scopus 로고    scopus 로고
    • Serum ferritin a predictor of iron overload in patients with thalassemia and sickle cell disease?
    • abst 3789
    • Pakbaz Z, Fischer R, Gamino R, et al. Serum ferritin a predictor of iron overload in patients with thalassemia and sickle cell disease? Blood 2004;104:abst 3789.
    • (2004) Blood , vol.104
    • Pakbaz, Z.1    Fischer, R.2    Gamino, R.3
  • 60
    • 0035138526 scopus 로고    scopus 로고
    • Progression of iron overload in sickle cell disease
    • Olivieri NF. Progression of iron overload in sickle cell disease. Semin Hematol 2001;38(Suppl 1):57-62.
    • (2001) Semin Hematol , vol.38 , Issue.SUPPL. 1 , pp. 57-62
    • Olivieri, N.F.1
  • 61
    • 66149149084 scopus 로고    scopus 로고
    • Hepatic iron overload in children with sickle cell anemia on chronic transfusion therapy
    • Brown K, Subramony C, May W, et al. Hepatic iron overload in children with sickle cell anemia on chronic transfusion therapy. J Pediatr Hematol Oncol 2009;31:309-312.
    • (2009) J Pediatr Hematol Oncol , vol.31 , pp. 309-312
    • Brown, K.1    Subramony, C.2    May, W.3
  • 62
    • 34547799156 scopus 로고    scopus 로고
    • Serum ferritin underestimates liver iron concentration in transfusion independent thalassemia patients as compared to regularly transfused thalassemia and sickle cell patients
    • Pakbaz Z, Fischer R, Fung E, et al. Serum ferritin underestimates liver iron concentration in transfusion independent thalassemia patients as compared to regularly transfused thalassemia and sickle cell patients. Pediatr Blood Cancer 2007;49:329-332.
    • (2007) Pediatr Blood Cancer , vol.49 , pp. 329-332
    • Pakbaz, Z.1    Fischer, R.2    Fung, E.3
  • 63
    • 73949153192 scopus 로고    scopus 로고
    • Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear, and are associated with iron load and liver injury
    • Adamkiewicz TV, Abboud MR, Paley C, et al. Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear, and are associated with iron load and liver injury. Blood 2009;114:4632-4638.
    • (2009) Blood , vol.114 , pp. 4632-4638
    • Adamkiewicz, T.V.1    Abboud, M.R.2    Paley, C.3
  • 64
    • 77951034604 scopus 로고    scopus 로고
    • Iron overload indices rise linearly with transfusion rate in patients with sickle cell disease
    • Inati A, Musallam K, Wood JC, Taher AT. Iron overload indices rise linearly with transfusion rate in patients with sickle cell disease. Blood 2010;115:2980-2981.
    • (2010) Blood , vol.115 , pp. 2980-2981
    • Inati, A.1    Musallam, K.2    Wood, J.C.3    Taher, A.T.4
  • 65
    • 84925562601 scopus 로고    scopus 로고
    • Nontransferrin-bound iron in transfused patients with sickle cell disease
    • Epub ahead of print DOI: 10.1111/j.1751-553x.2010.01255.x
    • Inati A, Musallam KM, Cappellini MD, et al. Nontransferrin-bound iron in transfused patients with sickle cell disease. Int J Lab Hematol 2010;[Epub ahead of print] DOI: 10.1111/j.1751-553x.2010.01255.x.
    • (2010) Int J Lab Hematol
    • Inati, A.1    Musallam, K.M.2    Cappellini, M.D.3
  • 67
    • 43449093775 scopus 로고    scopus 로고
    • Italian Society of Hematology practice guidelines for the management of iron overload in thalassemia major and related disorders
    • Angelucci E, Barosi G, Camaschella C, et al. Italian Society of Hematology practice guidelines for the management of iron overload in thalassemia major and related disorders. Haematologica 2008;93:741-752.
    • (2008) Haematologica , vol.93 , pp. 741-752
    • Angelucci, E.1    Barosi, G.2    Camaschella, C.3
  • 68
    • 70449349104 scopus 로고    scopus 로고
    • Effect of deferasirox (Exjade®) on labile plasma iron levels in heavily iron-overloaded patients with transfusion-dependent anemias enrolled in the large-scale, prospective 1-year EPIC trial
    • abst 3881
    • Porter JB, Cappellini MD, El-Beshlawy A, et al. Effect of deferasirox (Exjade®) on labile plasma iron levels in heavily iron-overloaded patients with transfusion-dependent anemias enrolled in the large-scale, prospective 1-year EPIC trial. Blood 2008;112:abst 3881.
    • (2008) Blood , vol.112
    • Porter, J.B.1    Cappellini, M.D.2    El-Beshlawy, A.3


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