-
1
-
-
0032474692
-
Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography
-
10.1056/NEJM199807023390102
-
Adams RJ, Mckie VC, Hsu L, Files B, Vichinsky E, Pegelow C, Abboud M, Gallagher D, Kutlar A, Nichols FT, Bonds DR, Brambilla D (1998) Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography. N Engl J Med 339:5-11 10.1056/NEJM199807023390102
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 5-11
-
-
Adams, R.J.1
Mckie, V.C.2
Hsu, L.3
Files, B.4
Vichinsky, E.5
Pegelow, C.6
Abboud, M.7
Gallagher, D.8
Kutlar, A.9
Nichols, F.T.10
Bonds, D.R.11
Brambilla, D.12
-
2
-
-
0023551183
-
Iron state and hepatic disease in patients with thalassemia major treated with long term subcutaneous desferrioxamine
-
Aldouri MA, Wonke B, Hoffbrand AV, Flynn DM, Laulicht M, Fenton LA, Scheuer PJ, Kibbler CC, Allwood CA, Brown D (1987) Iron state and hepatic disease in patients with thalassemia major treated with long term subcutaneous desferrioxamine. J Clin Pathol 40:1353-1359
-
(1987)
J. Clin. Pathol.
, vol.40
, pp. 1353-1359
-
-
Aldouri, M.A.1
Wonke, B.2
Hoffbrand, A.V.3
Flynn, D.M.4
Laulicht, M.5
Fenton, L.A.6
Scheuer, P.J.7
Kibbler, C.C.8
Allwood, C.A.9
Brown, D.10
-
3
-
-
0026643003
-
Efficacy and possible adverse effects of the oral chelator 1,2 dimethyl-3-hydraxypyrid-4-one (Li) in thalassemia major
-
Al-Refaie FN, Wonke B, Hoffbrand AV, Wickens DG, Nortey P, Kontoghiorghes GJ (1992) Efficacy and possible adverse effects of the oral chelator 1,2 dimethyl-3-hydraxypyrid-4-one (Li) in thalassemia major. Blood 80:593-599
-
(1992)
Blood
, vol.80
, pp. 593-599
-
-
Al-Refaie, F.N.1
Wonke, B.2
Hoffbrand, A.V.3
Wickens, D.G.4
Nortey, P.5
Kontoghiorghes, G.J.6
-
4
-
-
0028962119
-
Pharmacokinetics of the oral chelator deferiprone (L1) in patients with iron overload
-
Al-Refaie FN, Shephard LN, Nortey P, Wonke B, Hoffbrand AV (1995) Pharmacokinetics of the oral chelator deferiprone (L1) in patients with iron overload. Br J Haematol 89:403-408
-
(1995)
Br. J. Haematol.
, vol.89
, pp. 403-408
-
-
Al-Refaie, F.N.1
Shephard, L.N.2
Nortey, P.3
Wonke, B.4
Hoffbrand, A.V.5
-
5
-
-
18044399191
-
Cardiovascular T2-Star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload
-
Anderson LJ, Holden S, Davis B, Prescott E, Charrier CC, Bunce NH, Firmin DN, Wonke B, Porter J, Walker JM, Pennell DJ (2001) Cardiovascular T2-Star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J 22:2171-2179
-
(2001)
Eur. Heart J.
, vol.22
, pp. 2171-2179
-
-
Anderson, L.J.1
Holden, S.2
Davis, B.3
Prescott, E.4
Charrier, C.C.5
Bunce, N.H.6
Firmin, D.N.7
Wonke, B.8
Porter, J.9
Walker, J.M.10
Pennell, D.J.11
-
7
-
-
0019128329
-
The liver in sickle cell disease. A clinicopathologic study of 70 patients
-
Bower TW, Moore GW, Hutchins GM (1980) The liver in sickle cell disease. A clinicopathologic study of 70 patients. Am J Med 69:833-837
-
(1980)
Am. J. Med.
, vol.69
, pp. 833-837
-
-
Bower, T.W.1
Moore, G.W.2
Hutchins, G.M.3
-
8
-
-
0027463317
-
Hepatic iron stores and plasma ferritin concentration in patients with sickle cell anemia and thalassemia major
-
1:STN:280:ByyD1MfitVc%3D
-
Brittenham GM, Cohen AR, McLaren CE, Martin MB, Griffith PM, Nienhuis AW, Young NS, Allen CJ, Farrell DE, Harris JW (1993) Hepatic iron stores and plasma ferritin concentration in patients with sickle cell anemia and thalassemia major. Am J Hematol 42:81-85 1:STN:280:ByyD1MfitVc%3D
-
(1993)
Am. J. Hematol.
, vol.42
, pp. 81-85
-
-
Brittenham, G.M.1
Cohen, A.R.2
McLaren, C.E.3
Martin, M.B.4
Griffith, P.M.5
Nienhuis, A.W.6
Young, N.S.7
Allen, C.J.8
Farrell, D.E.9
Harris, J.W.10
-
9
-
-
0028059813
-
Efficacy of desferrioxamine in preventing complications of iron overload in patients with thalassemia major
-
Brittenham GM, Griffith PM, Nienhuis AW (1994) Efficacy of desferrioxamine in preventing complications of iron overload in patients with thalassemia major. N Engl J Med 331:567-573
-
(1994)
N. Engl. J. Med.
, vol.331
, pp. 567-573
-
-
Brittenham, G.M.1
Griffith, P.M.2
Nienhuis, A.W.3
-
10
-
-
0037217987
-
Noninvasive measurement of iron: Report of an NIDDK workshop
-
10.1182/blood-2002-06-1723
-
Brittenham GM, Badman DG (2003) Noninvasive measurement of iron: Report of an NIDDK workshop. Blood 101:15-19 10.1182/blood-2002-06-1723
-
(2003)
Blood
, vol.101
, pp. 15-19
-
-
Brittenham, G.M.1
Badman, D.G.2
-
11
-
-
0019502426
-
Treatment in sickle cell anemia
-
Charache S (1981) Treatment in sickle cell anemia. Annu Rev Med 32:195-206
-
(1981)
Annu. Rev. Med.
, vol.32
, pp. 195-206
-
-
Charache, S.1
-
12
-
-
0029025475
-
Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia
-
10.1056/NEJM199505183322001
-
Charache S, Terrin ML, Moore RD, Dover GJ, Barton FB, Eckert SV, McMahon RP, Bonds DR (1995) Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. N Engl J Med 332:1317-1322 10.1056/ NEJM199505183322001
-
(1995)
N. Engl. J. Med.
, vol.332
, pp. 1317-1322
-
-
Charache, S.1
Terrin, M.L.2
Moore, R.D.3
Dover, G.J.4
Barton, F.B.5
Eckert, S.V.6
McMahon, R.P.7
Bonds, D.R.8
-
13
-
-
0042943205
-
Safety and effectiveness of long-term therapy with the oral iron chelator deferiprone
-
Cohen AR, Galanello R, Piga A, De Sanctis V, Tricta F (2003) Safety and effectiveness of long-term therapy with the oral iron chelator deferiprone. Blood 102:1583-1587
-
(2003)
Blood
, vol.102
, pp. 1583-1587
-
-
Cohen, A.R.1
Galanello, R.2
Piga, A.3
De Sanctis, V.4
Tricta, F.5
-
14
-
-
0028345040
-
Iron-balance and dose-response studies of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in iron-loaded patients with sickle cell disease
-
Collins AF, Fassos FF, Stobie S, Lewis N, Shaw D, Fry M, Templeton DM, McClelland RA, Koren G, Olivieri NF (1994) Iron-balance and dose-response studies of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in iron-loaded patients with sickle cell disease. Blood 83:2329-2333
-
(1994)
Blood
, vol.83
, pp. 2329-2333
-
-
Collins, A.F.1
Fassos, F.F.2
Stobie, S.3
Lewis, N.4
Shaw, D.5
Fry, M.6
Templeton, D.M.7
McClelland, R.A.8
Koren, G.9
Olivieri, N.F.10
-
15
-
-
0030750414
-
Blood transfusion in sickle cell disease
-
Davies SC, Roberts-Harewood M (1997) Blood transfusion in sickle cell disease. Blood Rev 11:57-71
-
(1997)
Blood Rev.
, vol.11
, pp. 57-71
-
-
Davies, S.C.1
Roberts-Harewood, M.2
-
16
-
-
0034651775
-
Long-term outcome of continuous 24-hour deferiprone infusion via indwelling intravenous catheters in high-risk beta-thalassemia
-
Davis BA, Porter JB (2000) Long-term outcome of continuous 24-hour deferiprone infusion via indwelling intravenous catheters in high-risk beta-thalassemia. Blood 95:1229-1236
-
(2000)
Blood
, vol.95
, pp. 1229-1236
-
-
Davis, B.A.1
Porter, J.B.2
-
17
-
-
0037930751
-
Monitoring long-term efficacy of iron chelation therapy by deferiprone and desferrioxamine in patients with beta-thalassemia major: Application of SQUID biomagnetic liver susceptometry
-
Fischer R, Longo F, Nielsen P, Engelhardt R, Hider R, Piga A (2003) Monitoring long-term efficacy of iron chelation therapy by deferiprone and desferrioxamine in patients with beta-thalassemia major: Application of SQUID biomagnetic liver susceptometry. Br J Haematol 121:938-948
-
(2003)
Br. J. Haematol.
, vol.121
, pp. 938-948
-
-
Fischer, R.1
Longo, F.2
Nielsen, P.3
Engelhardt, R.4
Hider, R.5
Piga, A.6
-
18
-
-
0842283228
-
Non-invasive assessment of hepatic iron stores by MRI
-
Gandon Y, Olivie D, Guyader D, Aube C, Oberti F, Sebille V, Deugnier Y (2004) Non-invasive assessment of hepatic iron stores by MRI. Lancet 363:357-362
-
(2004)
Lancet
, vol.363
, pp. 357-362
-
-
Gandon, Y.1
Olivie, D.2
Guyader, D.3
Aube, C.4
Oberti, F.5
Sebille, V.6
Deugnier, Y.7
-
19
-
-
0034235835
-
Severity of iron overload in patients with sickle cell disease receiving chronic red blood cell transfusion therapy
-
Harmatz P, Butensky E, Quirolo K, Williams R, Ferrell L, Moyer T, Golden D, Neumayr L, Vichinsky E (2000) Severity of iron overload in patients with sickle cell disease receiving chronic red blood cell transfusion therapy. Blood 96:76-79
-
(2000)
Blood
, vol.96
, pp. 76-79
-
-
Harmatz, P.1
Butensky, E.2
Quirolo, K.3
Williams, R.4
Ferrell, L.5
Moyer, T.6
Golden, D.7
Neumayr, L.8
Vichinsky, E.9
-
20
-
-
0031985039
-
Long-term trial of deferiprone in 51 transfusion-dependent iron overload patients
-
Hoffbrand AV, AL-Refaie F, Davis B, Siritanakatkul N, Jackson BF, Cochrane J, Prescott E, Wonke B (1998) Long-term trial of deferiprone in 51 transfusion-dependent iron overload patients. Blood 91:295-300
-
(1998)
Blood
, vol.91
, pp. 295-300
-
-
Hoffbrand, A.V.1
AL-Refaie, F.2
Davis, B.3
Siritanakatkul, N.4
Jackson, B.F.5
Cochrane, J.6
Prescott, E.7
Wonke, B.8
-
21
-
-
0023489829
-
Effective chelation of iron in beta thalassaemia with the oral chelator 1,2 dimethyl-3-hydroxypyrid-4-one
-
Kontoghiorghes GJ, Aldouri MA, Hoffbrand AV, Barr J, Wonke B, Kourouclaris T, Sheppard L (1987) Effective chelation of iron in beta thalassaemia with the oral chelator 1,2 dimethyl-3-hydroxypyrid-4-one. Br Med J Clin Res Ed 295:1509-1512
-
(1987)
Br. Med. J. Clin. Res. Ed.
, vol.295
, pp. 1509-1512
-
-
Kontoghiorghes, G.J.1
Aldouri, M.A.2
Hoffbrand, A.V.3
Barr, J.4
Wonke, B.5
Kourouclaris, T.6
Sheppard, L.7
-
22
-
-
0025007785
-
Pharmacokinetic studies in humans with the oral iron chelator 1,2 dimethyl-3-hydroxypyrid-4-one
-
Kontoghiorghes GJ, Goddurd JG, Bartlett AN, Sheppard L (1990) Pharmacokinetic studies in humans with the oral iron chelator 1,2 dimethyl-3-hydroxypyrid-4-one. Clin Pharmacol Ther 48:255-261
-
(1990)
Clin. Pharmacol. Ther.
, vol.48
, pp. 255-261
-
-
Kontoghiorghes, G.J.1
Goddurd, J.G.2
Bartlett, A.N.3
Sheppard, L.4
-
23
-
-
0034521888
-
Reduction of the clinical severity of sickle cell/beta-thalassemia with hydroxyurea: The experience of a single center in Greece
-
Loukopoulos L, Voskaridou E, Kalotychou V, Schina M, Loutradi A, Theodoropoulos I (2000) Reduction of the clinical severity of sickle cell/beta-thalassemia with hydroxyurea: The experience of a single center in Greece. Blood Cells Mol Dis 26:453-466
-
(2000)
Blood Cells Mol. Dis.
, vol.26
, pp. 453-466
-
-
Loukopoulos, L.1
Voskaridou, E.2
Kalotychou, V.3
Schina, M.4
Loutradi, A.5
Theodoropoulos, I.6
-
24
-
-
0034631379
-
Survival in beta-thalassaemia major in the United Kingdom: Data from the UK thalassaemia register
-
10.1016/S0140-6736(00)02357-6 (letter)
-
Modell B, Khan M, Darlison M (2000) Survival in beta-thalassaemia major in the United Kingdom: Data from the UK thalassaemia register (letter). Lancet 355:2051-2052 10.1016/S0140-6736(00)02357-6
-
(2000)
Lancet
, vol.355
, pp. 2051-2052
-
-
Modell, B.1
Khan, M.2
Darlison, M.3
-
25
-
-
0028898064
-
Iron chelation therapy with oral deferiprone in patients with thalassemia major
-
Olivieri NF, Brittenham GM, Matsui D, Berkovitch M, Blendis LM, Cameron RG, McClelland RA, Liu PP, Templeton DM, Koren G (1995) Iron chelation therapy with oral deferiprone in patients with thalassemia major. N Engl J Med 332:918-922
-
(1995)
N. Engl. J. Med.
, vol.332
, pp. 918-922
-
-
Olivieri, N.F.1
Brittenham, G.M.2
Matsui, D.3
Berkovitch, M.4
Blendis, L.M.5
Cameron, R.G.6
McClelland, R.A.7
Liu, P.P.8
Templeton, D.M.9
Koren, G.10
-
26
-
-
0031001278
-
Iron chelation therapy and treatment of thalassemia
-
1:CAS:528:DyaK2sXptVGntg%3D%3D
-
Olivieri NF, Brittenham GM (1997) Iron chelation therapy and treatment of thalassemia. Blood 89:739-761 1:CAS:528:DyaK2sXptVGntg%3D%3D
-
(1997)
Blood
, vol.89
, pp. 739-761
-
-
Olivieri, N.F.1
Brittenham, G.M.2
-
27
-
-
0038187626
-
Comparative effects of deferiprone and deferoxamine on survival and cardiac disease in patients with thalassemia major: A retrospective analysis
-
Piga A, Gaglioti C, Fogliacco E, Tricta F (2003) Comparative effects of deferiprone and deferoxamine on survival and cardiac disease in patients with thalassemia major: A retrospective analysis. Haematologica 88:489-496
-
(2003)
Haematologica
, vol.88
, pp. 489-496
-
-
Piga, A.1
Gaglioti, C.2
Fogliacco, E.3
Tricta, F.4
-
28
-
-
0028291736
-
Mortality in sickle cell disease. Life expectancy and risk factors for early death
-
10.1056/NEJM199406093302303
-
Platt OS, Brambilla DJ, Rosse WC, Milner PF, Castro O, Steinberg MH, Klugg PP (1994) Mortality in sickle cell disease. Life expectancy and risk factors for early death. N Engl J Med 330:1639-1644 10.1056/ NEJM199406093302303
-
(1994)
N. Engl. J. Med.
, vol.330
, pp. 1639-1644
-
-
Platt, O.S.1
Brambilla, D.J.2
Rosse, W.C.3
Milner, P.F.4
Castro, O.5
Steinberg, M.H.6
Klugg, P.P.7
-
29
-
-
0023613154
-
Transfusion and exchange transfusions in sickle cell anemias with particular reference to iron metabolism
-
Porter JB, Herhns ER (1987) Transfusion and exchange transfusions in sickle cell anemias with particular reference to iron metabolism. Acta Haematol 78:198-205
-
(1987)
Acta Haematol.
, vol.78
, pp. 198-205
-
-
Porter, J.B.1
Herhns, E.R.2
-
30
-
-
0036431540
-
Monitoring chelation to achieve optimal outcome in the treatment of thalassemia
-
Porter JB, Davis AB (2002) Monitoring chelation to achieve optimal outcome in the treatment of thalassemia. Best Pract Res Clin Haematol 15:329-368
-
(2002)
Best Pract. Res. Clin. Haematol.
, vol.15
, pp. 329-368
-
-
Porter, J.B.1
Davis, A.B.2
-
31
-
-
0014852644
-
The liver in sickle cell anaemia. A clinical-pathologic study
-
Rosenblate HJ, Eisenstein R, Holmes AW (1970) The liver in sickle cell anaemia. A clinical-pathologic study. Arch Pathol 90:235-243
-
(1970)
Arch. Pathol.
, vol.90
, pp. 235-243
-
-
Rosenblate, H.J.1
Eisenstein, R.2
Holmes, A.W.3
-
32
-
-
0029097965
-
Deferiprone (L1) chelates pathologic iron deposits from membranes of intact thalassemic and sickle red blood cells both in vitro and in vivo
-
Shalev O, Repka T, Goldfarb A, Grinberg L, Abrahamov A, Olivieri NF, Rachmilewitz EA, Hebbel RP (1995) Deferiprone (L1) chelates pathologic iron deposits from membranes of intact thalassemic and sickle red blood cells both in vitro and in vivo. Blood 86:2008-2013
-
(1995)
Blood
, vol.86
, pp. 2008-2013
-
-
Shalev, O.1
Repka, T.2
Goldfarb, A.3
Grinberg, L.4
Abrahamov, A.5
Olivieri, N.F.6
Rachmilewitz, E.A.7
Hebbel, R.P.8
-
33
-
-
0032589580
-
Transport of 14C-deferiprone in normal, thalassaemic and sickle red blood cells
-
Shalev O, Hileti D, Nortey P, Hebbel RP, Hoffbrand VA (1999) Transport of 14C-deferiprone in normal, thalassaemic and sickle red blood cells. Br J Haematol 105:1081-1083
-
(1999)
Br. J. Haematol.
, vol.105
, pp. 1081-1083
-
-
Shalev, O.1
Hileti, D.2
Nortey, P.3
Hebbel, R.P.4
Hoffbrand, V.A.5
-
34
-
-
11244355277
-
Non-invasive measurement and imaging of liver iron concentrations using proton magnetic resonance
-
St. Pierre TG, Clark PR, Chua-Anusorn W, Fleming AJ, Jeffrey GP, Olynyk JK, Pootrakul P, Robins E, Lindeman R (2005) Non-invasive measurement and imaging of liver iron concentrations using proton magnetic resonance. Blood 105:855-861
-
(2005)
Blood
, vol.105
, pp. 855-861
-
-
St. Pierre, T.G.1
Clark, P.R.2
Chua-Anusorn, W.3
Fleming, A.J.4
Jeffrey, G.P.5
Olynyk, J.K.6
Pootrakul, P.7
Robins, E.8
Lindeman, R.9
-
35
-
-
0032752004
-
The perioperative complication rate of orthopedic surgery in sickle cell disease: Report of the National Sickle Cell Surgery Study Group
-
Vichinsky EP, Neumayr LD, Haberkern C, Earles AN, Eckman J, Koshy M, Black DM (1999) The perioperative complication rate of orthopedic surgery in sickle cell disease: Report of the National Sickle Cell Surgery Study Group. Am J Hematol 62:129-138
-
(1999)
Am. J. Hematol.
, vol.62
, pp. 129-138
-
-
Vichinsky, E.P.1
Neumayr, L.D.2
Haberkern, C.3
Earles, A.N.4
Eckman, J.5
Koshy, M.6
Black, D.M.7
-
36
-
-
0037236871
-
Tissue Doppler echocardiography in patients with thalassemia detects early myocardial dysfunction related to myocardial iron overload
-
Vogel M, Anderson LJ, Holden S, Deanfield JE, Pennell DJ, Walker JM (2003) Tissue Doppler echocardiography in patients with thalassemia detects early myocardial dysfunction related to myocardial iron overload. Eur Heart J 24:113-119
-
(2003)
Eur. Heart J.
, vol.24
, pp. 113-119
-
-
Vogel, M.1
Anderson, L.J.2
Holden, S.3
Deanfield, J.E.4
Pennell, D.J.5
Walker, J.M.6
-
37
-
-
4544301060
-
Magnetic resonance imaging (MRI) in the evaluation of iron overload in patients with beta thalassaemia and sickle cell disease
-
Voskaridou E, Douskou M, Terpos E, Papassotiriou I, Stamoulakatou A, Ourailidis A, Loutradi A, Loukopoulos D (2004) Magnetic resonance imaging (MRI) in the evaluation of iron overload in patients with beta thalassaemia and sickle cell disease. Br J Haematol 126:736-742
-
(2004)
Br. J. Haematol.
, vol.126
, pp. 736-742
-
-
Voskaridou, E.1
Douskou, M.2
Terpos, E.3
Papassotiriou, I.4
Stamoulakatou, A.5
Ourailidis, A.6
Loutradi, A.7
Loukopoulos, D.8
-
38
-
-
0027510623
-
Transfusion management of sickle cell disease
-
Wayne AS, Kevy SV, Nathan DG (1993) Transfusion management of sickle cell disease. Blood 81:1109-1123
-
(1993)
Blood
, vol.81
, pp. 1109-1123
-
-
Wayne, A.S.1
Kevy, S.V.2
Nathan, D.G.3
-
39
-
-
1442307460
-
Myocardial iron loading in transfusion-dependent thalassemia and sickle cell disease
-
Wood JC, Tyszka JM, Carson S, Nelson M, Coates T (2004) Myocardial iron loading in transfusion-dependent thalassemia and sickle cell disease. Blood 103:1934-1936
-
(2004)
Blood
, vol.103
, pp. 1934-1936
-
-
Wood, J.C.1
Tyszka, J.M.2
Carson, S.3
Nelson, M.4
Coates, T.5
|