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Volumn 1, Issue 5, 2010, Pages

A role for DNA sequence in controlling the spatial organization of the genome

Author keywords

DNA zip code; Gene positioning; Nuclear periphery; Saccharomyces cerevisiae; Transcription

Indexed keywords

ARTICLE; CELL NUCLEUS; CELL STRESS; DNA REPAIR; DNA SEQUENCE; FUNGAL GENE; GENE EXPRESSION; GENE LOCATION; GENE LOCUS; GENETIC ORGANIZATION; MOLECULAR INTERACTION; NONHUMAN; NUCLEAR PORE COMPLEX; PROMOTER REGION; PROTEIN FOLDING; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION INITIATION; FUNGAL GENOME; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; NUCLEAR PORE; NUCLEOTIDE SEQUENCE;

EID: 77957679653     PISSN: 19491034     EISSN: 19491042     Source Type: Journal    
DOI: 10.4161/nucl.1.5.12637     Document Type: Article
Times cited : (8)

References (52)
  • 1
    • 0001144847 scopus 로고
    • Über Zeillteilung
    • In: Gegenbaur C, ed
    • Rabl C. Über Zeillteilung. In: Gegenbaur C, ed. Morphol Jahrbuch 1885; 214-330.
    • (1885) Morphol Jahrbuch , pp. 214-330
    • Rabl, C.1
  • 2
    • 0001169778 scopus 로고
    • Die blastermerenkerne von Ascaris megalocephala und die theorie der chromosomenindividualität
    • Boveri T. Die blastermerenkerne von Ascaris megalocephala und die theorie der chromosomenindividualität. Arch Zellforschung 1909; 3:181.
    • (1909) Arch Zellforschung , vol.3 , pp. 181
    • Boveri, T.1
  • 4
    • 0037023361 scopus 로고    scopus 로고
    • Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development
    • Kosak ST, Skok JA, Medina KL, Riblet R, Le Beau MM, Fisher AG, et al. Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science 2002; 296:158-62.
    • (2002) Science , vol.296 , pp. 158-162
    • Kosak, S.T.1    Skok, J.A.2    Medina, K.L.3    Riblet, R.4    le Beau, M.M.5    Fisher, A.G.6
  • 5
    • 4544255977 scopus 로고    scopus 로고
    • Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei
    • Zink D, Amaral MD, Englmann A, Lang S, Clarke LA, Rudolph C, et al. Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei. J Cell Biol 2004; 166:815-25.
    • (2004) J Cell Biol , vol.166 , pp. 815-825
    • Zink, D.1    Amaral, M.D.2    Englmann, A.3    Lang, S.4    Clarke, L.A.5    Rudolph, C.6
  • 6
    • 31644436473 scopus 로고    scopus 로고
    • Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus
    • Williams RR, Azuara V, Perry P, Sauer S, Dvorkina M, Jorgensen H, et al. Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus. J Cell Sci 2006; 119:132-40.
    • (2006) J Cell Sci , vol.119 , pp. 132-140
    • Williams, R.R.1    Azuara, V.2    Perry, P.3    Sauer, S.4    Dvorkina, M.5    Jorgensen, H.6
  • 7
    • 33744779614 scopus 로고    scopus 로고
    • The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation
    • Ragoczy T, Bender MA, Telling A, Byron R, Groudine M. The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation. Genes Dev 2006; 20:1447-57.
    • (2006) Genes Dev , vol.20 , pp. 1447-1457
    • Ragoczy, T.1    Bender, M.A.2    Telling, A.3    Byron, R.4    Groudine, M.5
  • 8
  • 9
    • 33847077659 scopus 로고    scopus 로고
    • Beyond the sequence: Cellular organization of genome function
    • Misteli T. Beyond the sequence: cellular organization of genome function. Cell 2007; 128:787-800.
    • (2007) Cell , vol.128 , pp. 787-800
    • Misteli, T.1
  • 10
    • 33751203862 scopus 로고    scopus 로고
    • SnapShot: Cellular bodies
    • Spector DL. SnapShot: Cellular bodies. Cell 2006; 127:1071.
    • (2006) Cell , vol.127 , pp. 1071
    • Spector, D.L.1
  • 11
    • 52949133457 scopus 로고    scopus 로고
    • The meaning of gene positioning
    • Takizawa T, Meaburn KJ, Misteli T. The meaning of gene positioning. Cell 2008; 135:9-13.
    • (2008) Cell , vol.135 , pp. 9-13
    • Takizawa, T.1    Meaburn, K.J.2    Misteli, T.3
  • 12
    • 0017652886 scopus 로고
    • The structure of histone-depleted metaphase chromosomes
    • Paulson JR, Laemmli UK. The structure of histone-depleted metaphase chromosomes. Cell 1977; 12:817-28.
    • (1977) Cell , vol.12 , pp. 817-828
    • Paulson, J.R.1    Laemmli, U.K.2
  • 13
    • 0025045803 scopus 로고
    • Drosophila scaffold-attached regions bind nuclear scaffolds and can function as ARS elements in both budding and fission yeasts
    • Amati B, Gasser SM. Drosophila scaffold-attached regions bind nuclear scaffolds and can function as ARS elements in both budding and fission yeasts. Mol Cell Biol 1990; 10:5442-54.
    • (1990) Mol Cell Biol , vol.10 , pp. 5442-5454
    • Amati, B.1    Gasser, S.M.2
  • 14
    • 0029969424 scopus 로고    scopus 로고
    • Specific interactions of chromatin with the nuclear envelope: Positional determination within the nucleus in Drosophila melanogaster
    • Marshall WF, Dernburg AF, Harmon B, Agard DA, Sedat JW. Specific interactions of chromatin with the nuclear envelope: positional determination within the nucleus in Drosophila melanogaster. Mol Biol Cell 1996; 7:825-42.
    • (1996) Mol Biol Cell , vol.7 , pp. 825-842
    • Marshall, W.F.1    Dernburg, A.F.2    Harmon, B.3    Agard, D.A.4    Sedat, J.W.5
  • 15
    • 45149084413 scopus 로고    scopus 로고
    • Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
    • Guelen L, Pagie L, Brasset E, Meuleman W, Faza MB, Talhout W, et al. Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions. Nature 2008; 453:948-51.
    • (2008) Nature , vol.453 , pp. 948-951
    • Guelen, L.1    Pagie, L.2    Brasset, E.3    Meuleman, W.4    Faza, M.B.5    Talhout, W.6
  • 16
    • 18844412748 scopus 로고    scopus 로고
    • Developmentally induced changes in transcriptional program alter spatial organization across chromosomes
    • Casolari JM, Brown CR, Drubin DA, Rando OJ, Silver PA. Developmentally induced changes in transcriptional program alter spatial organization across chromosomes. Genes Dev 2005; 19:1188-98.
    • (2005) Genes Dev , vol.19 , pp. 1188-1198
    • Casolari, J.M.1    Brown, C.R.2    Drubin, D.A.3    Rando, O.J.4    Silver, P.A.5
  • 17
    • 2342501365 scopus 로고    scopus 로고
    • Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization
    • Casolari JM, Brown CR, Komili S, West J, Hieronymus H, Silver PA. Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization. Cell 2004; 117:427-39.
    • (2004) Cell , vol.117 , pp. 427-439
    • Casolari, J.M.1    Brown, C.R.2    Komili, S.3    West, J.4    Hieronymus, H.5    Silver, P.A.6
  • 18
    • 14044266853 scopus 로고    scopus 로고
    • Gene recruitment of the activated INO1 locus to the nuclear membrane
    • Brickner JH, Walter P. Gene recruitment of the activated INO1 locus to the nuclear membrane. PLoS Biol 2004; 2:342.
    • (2004) PLoS Biol , vol.2 , pp. 342
    • Brickner, J.H.1    Walter, P.2
  • 19
    • 33750320374 scopus 로고    scopus 로고
    • Cotranscriptional recruitment to the mRNA export receptor Mex67p contributes to nuclear pore anchoring of activated genes
    • Dieppois G, Iglesias N, Stutz F. Cotranscriptional recruitment to the mRNA export receptor Mex67p contributes to nuclear pore anchoring of activated genes. Mol Cell Biol 2006; 26:7858-70.
    • (2006) Mol Cell Biol , vol.26 , pp. 7858-7870
    • Dieppois, G.1    Iglesias, N.2    Stutz, F.3
  • 20
    • 34249003318 scopus 로고    scopus 로고
    • Glucose-responsive regulators of gene expression in Saccharomyces cerevisiae function at the nuclear periphery via a reverse recruitment mechanism
    • Sarma NJ, Haley TM, Barbara KE, Buford TD, Willis KA, Santangelo GM. Glucose-responsive regulators of gene expression in Saccharomyces cerevisiae function at the nuclear periphery via a reverse recruitment mechanism. Genetics 2007; 175:1127-35.
    • (2007) Genetics , vol.175 , pp. 1127-1135
    • Sarma, N.J.1    Haley, T.M.2    Barbara, K.E.3    Buford, T.D.4    Willis, K.A.5    Santangelo, G.M.6
  • 21
    • 34247341747 scopus 로고    scopus 로고
    • H2A.Z-mediated localization of genes at the nuclear periphery confers epigenetic memory of previous transcriptional state
    • Brickner DG, Cajigas IC, Fondufe-Mittendorf Y, Ahmed S, Lee PC, Widom J, et al. H2A.Z-mediated localization of genes at the nuclear periphery confers epigenetic memory of previous transcriptional state. PLoS Biol 2007; 5:e81.
    • (2007) PLoS Biol , vol.5
    • Brickner, D.G.1    Cajigas, I.C.2    Fondufe-Mittendorf, Y.3    Ahmed, S.4    Lee, P.C.5    Widom, J.6
  • 24
    • 40349113413 scopus 로고    scopus 로고
    • Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes
    • Brown CR, Kennedy CJ, Delmar VA, Forbes DJ, Silver PA. Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes. Genes Dev 2008; 22:627-39.
    • (2008) Genes Dev , vol.22 , pp. 627-639
    • Brown, C.R.1    Kennedy, C.J.2    Delmar, V.A.3    Forbes, D.J.4    Silver, P.A.5
  • 25
    • 33644870525 scopus 로고    scopus 로고
    • Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila
    • Mendjan S, Taipale M, Kind J, Holz H, Gebhardt P, Schelder M, et al. Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila. Mol Cell 2006; 21:811-23.
    • (2006) Mol Cell , vol.21 , pp. 811-823
    • Mendjan, S.1    Taipale, M.2    Kind, J.3    Holz, H.4    Gebhardt, P.5    Schelder, M.6
  • 26
    • 0031972489 scopus 로고    scopus 로고
    • Mapping three-dimensional chromosome architecture in situ
    • Dernburg AF, Sedat JW. Mapping three-dimensional chromosome architecture in situ. Methods Cell Biol 1998; 53:187-233.
    • (1998) Methods Cell Biol , vol.53 , pp. 187-233
    • Dernburg, A.F.1    Sedat, J.W.2
  • 27
    • 0033063475 scopus 로고    scopus 로고
    • Analysis of nuclear organization in Saccharomyces cerevisiae
    • Gotta M, Laroche T, Gasser SM. Analysis of nuclear organization in Saccharomyces cerevisiae. Methods Enzymol 1999; 304:663-72.
    • (1999) Methods Enzymol , vol.304 , pp. 663-672
    • Gotta, M.1    Laroche, T.2    Gasser, S.M.3
  • 28
    • 0035371920 scopus 로고    scopus 로고
    • Visualizing chromosome dynamics with GFP
    • Belmont AS. Visualizing chromosome dynamics with GFP. Trends Cell Biol 2001; 11:250-7.
    • (2001) Trends Cell Biol , vol.11 , pp. 250-257
    • Belmont, A.S.1
  • 29
    • 75749103380 scopus 로고    scopus 로고
    • Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes
    • Capelson M, Liang Y, Schulte R, Mair W, Wagner U, Hetzer MW. Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes. Cell 2010; 140:372-83.
    • (2010) Cell , vol.140 , pp. 372-383
    • Capelson, M.1    Liang, Y.2    Schulte, R.3    Mair, W.4    Wagner, U.5    Hetzer, M.W.6
  • 30
    • 77649210955 scopus 로고    scopus 로고
    • Nuclear pore proteins nup153 and megator define transcriptionally active regions in the Drosophila genome
    • Vaquerizas JM, Suyama R, Kind J, Miura K, Luscombe NM, Akhtar A. Nuclear pore proteins nup153 and megator define transcriptionally active regions in the Drosophila genome. PLoS Genet 2010; 6:1000846.
    • (2010) PLoS Genet , vol.6 , pp. 1000846
    • Vaquerizas, J.M.1    Suyama, R.2    Kind, J.3    Miura, K.4    Luscombe, N.M.5    Akhtar, A.6
  • 31
    • 75749117571 scopus 로고    scopus 로고
    • Nucleoporins directly stimulate expression of developmental and cell cycle genes inside the nucleoplasm
    • Kalverda B, Pickersgill H, Shloma VV, Fornerod M. Nucleoporins directly stimulate expression of developmental and cell cycle genes inside the nucleoplasm. Cell 2010; 140:360-71.
    • (2010) Cell , vol.140 , pp. 360-371
    • Kalverda, B.1    Pickersgill, H.2    Shloma, V.V.3    Fornerod, M.4
  • 32
    • 34250777112 scopus 로고    scopus 로고
    • The nuclear envelope and transcriptional control
    • Akhtar A, Gasser SM. The nuclear envelope and transcriptional control. Nat Rev Genet 2007; 8:507-17.
    • (2007) Nat Rev Genet , vol.8 , pp. 507-517
    • Akhtar, A.1    Gasser, S.M.2
  • 33
    • 0032490917 scopus 로고    scopus 로고
    • Perinuclear localization of chromatin facilitates transcriptional silencing
    • Andrulis ED, Neiman AM, Zappulla DC, Sternglanz R. Perinuclear localization of chromatin facilitates transcriptional silencing. Nature 1998; 394:592-5.
    • (1998) Nature , vol.394 , pp. 592-595
    • Andrulis, E.D.1    Neiman, A.M.2    Zappulla, D.C.3    Sternglanz, R.4
  • 34
    • 40749122641 scopus 로고    scopus 로고
    • Transcriptional repression mediated by repositioning of genes to the nuclear lamina
    • Reddy KL, Zullo JM, Bertolino E, Singh H. Transcriptional repression mediated by repositioning of genes to the nuclear lamina. Nature 2008; 452:243-7.
    • (2008) Nature , vol.452 , pp. 243-247
    • Reddy, K.L.1    Zullo, J.M.2    Bertolino, E.3    Singh, H.4
  • 35
    • 0037205232 scopus 로고    scopus 로고
    • Chromatin boundaries in budding yeast: The nuclear pore connection
    • Ishii K, Arib G, Lin C, Van Houwe G, Laemmli UK. Chromatin boundaries in budding yeast: the nuclear pore connection. Cell 2002; 109:551-62.
    • (2002) Cell , vol.109 , pp. 551-562
    • Ishii, K.1    Arib, G.2    Lin, C.3    van Houwe, G.4    Laemmli, U.K.5
  • 38
    • 33744977019 scopus 로고    scopus 로고
    • Nuclear pore association confers optimal expression levels for an inducible yeast gene
    • Taddei A, Van Houwe G, Hediger F, Kalck V, Cubizolles F, Schober H, et al. Nuclear pore association confers optimal expression levels for an inducible yeast gene. Nature 2006; 441:774-8.
    • (2006) Nature , vol.441 , pp. 774-778
    • Taddei, A.1    van Houwe, G.2    Hediger, F.3    Kalck, V.4    Cubizolles, F.5    Schober, H.6
  • 39
    • 17644419993 scopus 로고    scopus 로고
    • Reverse recruitment: The Nup84 nuclear pore subcomplex mediates Rap1/ Gcr1/Gcr2 transcriptional activation
    • Menon BB, Sarma NJ, Pasula S, Deminoff SJ, Willis KA, Barbara KE, et al. Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/ Gcr1/Gcr2 transcriptional activation. Proc Natl Acad Sci USA 2005; 102:5749-54.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5749-5754
    • Menon, B.B.1    Sarma, N.J.2    Pasula, S.3    Deminoff, S.J.4    Willis, K.A.5    Barbara, K.E.6
  • 40
    • 77950920142 scopus 로고    scopus 로고
    • The spatial dynamics of tissue-specific promoters during C. elegans development
    • Meister P, Towbin BD, Pike BL, Ponti A, Gasser SM. The spatial dynamics of tissue-specific promoters during C. elegans development. Genes Dev 2010; 24:766-82.
    • (2010) Genes Dev , vol.24 , pp. 766-782
    • Meister, P.1    Towbin, B.D.2    Pike, B.L.3    Ponti, A.4    Gasser, S.M.5
  • 41
    • 73349090560 scopus 로고    scopus 로고
    • Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells
    • Schoenfelder S, Sexton T, Chakalova L, Cope NF, Horton A, Andrews S, et al. Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells. Nat Genet 2010; 42:53-61.
    • (2010) Nat Genet , vol.42 , pp. 53-61
    • Schoenfelder, S.1    Sexton, T.2    Chakalova, L.3    Cope, N.F.4    Horton, A.5    Andrews, S.6
  • 42
    • 0030479611 scopus 로고    scopus 로고
    • Nuclear organization and transcriptional silencing in yeast
    • Gotta M, Gasser SM. Nuclear organization and transcriptional silencing in yeast. Experientia 1996; 52:1136-47.
    • (1996) Experientia , vol.52 , pp. 1136-1147
    • Gotta, M.1    Gasser, S.M.2
  • 43
    • 0029746494 scopus 로고    scopus 로고
    • Evidence for silencing compartments within the yeast nucleus: A role for telomere proximity and Sir protein concentration in silencer- mediated repression
    • Maillet L, Boscheron C, Gotta M, Marcand S, Gilson E, Gasser SM. Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer- mediated repression. Genes Dev 1996; 10:1796-811.
    • (1996) Genes Dev , vol.10 , pp. 1796-1811
    • Maillet, L.1    Boscheron, C.2    Gotta, M.3    Marcand, S.4    Gilson, E.5    Gasser, S.M.6
  • 44
    • 63849287611 scopus 로고    scopus 로고
    • The functional importance of telomere clustering: Global changes in gene expression result from SIR factor dispersion
    • Taddei A, Van Houwe G, Nagai S, Erb I, van Nimwegen E, Gasser SM. The functional importance of telomere clustering: global changes in gene expression result from SIR factor dispersion. Genome Res 2009; 19:611-25.
    • (2009) Genome Res , vol.19 , pp. 611-625
    • Taddei, A.1    van Houwe, G.2    Nagai, S.3    Erb, I.4    van Nimwegen, E.5    Gasser, S.M.6
  • 45
    • 33745001795 scopus 로고    scopus 로고
    • SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope
    • Cabal GG, Genovesio A, Rodriguez-Navarro S, Zimmer C, Gadal O, Lesne A, et al. SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope. Nature 2006; 441:770-3.
    • (2006) Nature , vol.441 , pp. 770-773
    • Cabal, G.G.1    Genovesio, A.2    Rodriguez-Navarro, S.3    Zimmer, C.4    Gadal, O.5    Lesne, A.6
  • 46
    • 34047254106 scopus 로고    scopus 로고
    • Actively transcribed GAL genes can be physically linked to the nuclear pore by the SAGA chromatin modifying complex
    • Luthra R, Kerr SC, Harreman MT, Apponi LH, Fasken MB, Ramineni S, et al. Actively transcribed GAL genes can be physically linked to the nuclear pore by the SAGA chromatin modifying complex. J Biol Chem 2007; 282:3042-9.
    • (2007) J Biol Chem , vol.282 , pp. 3042-3049
    • Luthra, R.1    Kerr, S.C.2    Harreman, M.T.3    Apponi, L.H.4    Fasken, M.B.5    Ramineni, S.6
  • 47
    • 38049013812 scopus 로고    scopus 로고
    • Sus1, Sac3 and Thp1 mediate post-transcriptional tethering of active genes to the nuclear rim as well as to non-nascent mRNP
    • Chekanova JA, Abruzzi KC, Rosbash M, Belostotsky DA. Sus1, Sac3 and Thp1 mediate post-transcriptional tethering of active genes to the nuclear rim as well as to non-nascent mRNP. RNA 2008; 14:66-77.
    • (2008) RNA , vol.14 , pp. 66-77
    • Chekanova, J.A.1    Abruzzi, K.C.2    Rosbash, M.3    Belostotsky, D.A.4
  • 48
    • 10744233477 scopus 로고    scopus 로고
    • Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery
    • Rodriguez-Navarro S, Fischer T, Luo MJ, Antunez O, Brettschneider S, Lechner J, et al. Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery. Cell 2004; 116:75-86.
    • (2004) Cell , vol.116 , pp. 75-86
    • Rodriguez-Navarro, S.1    Fischer, T.2    Luo, M.J.3    Antunez, O.4    Brettschneider, S.5    Lechner, J.6
  • 49
    • 0036838096 scopus 로고    scopus 로고
    • Differential requirement of SAGA components for recruitment of TATA-boxbinding protein to promoters in vivo
    • Bhaumik SR, Green MR. Differential requirement of SAGA components for recruitment of TATA-boxbinding protein to promoters in vivo. Mol Cell Biol 2002; 22:7365-71.
    • (2002) Mol Cell Biol , vol.22 , pp. 7365-7371
    • Bhaumik, S.R.1    Green, M.R.2
  • 50
    • 0038016723 scopus 로고    scopus 로고
    • TFIIB and subunits of the SAGA complex are involved in transcriptional activation of phospholipid biosynthetic genes by the regulatory protein Ino2 in the yeast Saccharomyces cerevisiae
    • Dietz M, Heyken WT, Hoppen J, Geburtig S, Schuller HJ. TFIIB and subunits of the SAGA complex are involved in transcriptional activation of phospholipid biosynthetic genes by the regulatory protein Ino2 in the yeast Saccharomyces cerevisiae. Mol Microbiol 2003; 48:1119-30.
    • (2003) Mol Microbiol , vol.48 , pp. 1119-1130
    • Dietz, M.1    Heyken, W.T.2    Hoppen, J.3    Geburtig, S.4    Schuller, H.J.5
  • 51
    • 0344338368 scopus 로고
    • Gene gating: A hypothesis
    • Blobel G. Gene gating: a hypothesis. Proc Natl Acad Sci USA 1985; 82:8527-9.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 8527-8529
    • Blobel, G.1
  • 52
    • 62849083222 scopus 로고    scopus 로고
    • The emerging role of nuclear architecture in DNA repair and genome maintenance
    • Misteli T, Soutoglou E. The emerging role of nuclear architecture in DNA repair and genome maintenance. Nat Rev Mol Cell Biol 2009; 10:243-54.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 243-254
    • Misteli, T.1    Soutoglou, E.2


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