Effects of magnesium ions on recombinant human furin: Selective activation of hydrolytic activity upon substrates derived from virus envelope glycoprotein

Biological Chemistry

Volumn 391, Issue 9, 2010, Pages 1105-1112

  Izidoro, Mario A ^a   Assis, Diego M ^a   Oliveira, Vitor ^a   Santos, Jorge A N ^a   Juliano, Maria A ^a   Lindberg, Iris ^b   Juliano, Luiz ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

fluorescence; magnesium; peptidase; protease

Indexed keywords

FURIN; MAGNESIUM CHLORIDE; MAGNESIUM ION; POLYPEPTIDE; RECOMBINANT PROTEIN; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BORNA DISEASE VIRUS; CORONAVIRUS; ENZYME ACTIVITY; FILOVIRIDAE; FLAVIVIRUS; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HERPES VIRUS; HUMAN; HYDROLYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOMYXOVIRUS; PARAMYXOVIRUS; PEPTIDE ANALYSIS; PEPTIDE SYNTHESIS; PH; PRIORITY JOURNAL; PROTEIN BINDING; RETROVIRUS; SACCHAROMYCES; VIRUS ENVELOPE; VIRUS INFECTION;

BIOCATALYSIS; ENZYME ACTIVATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; FURIN; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; INFLUENZA A VIRUS, H5N1 SUBTYPE; IONS; MAGNESIUM; OLIGOPEPTIDES; PROPROTEIN CONVERTASES; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUBSTRATE SPECIFICITY; VIRAL ENVELOPE PROTEINS;

AVES; EUKARYOTA; MEASLES VIRUS;

EID: 77957605073     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2010.114     Document Type: Article

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