Clinical and experimental pancreatic islet transplantation to striated muscle: Establishment of a vascular system similar to that in native islets

Diabetes

Volumn 59, Issue 10, 2010, Pages 2569-2578

  Christoffersson, Gustaf ^a   Henriksnäs, Johanna ^a   Johansson, Lars ^a   Rolny, Charlotte ^a   Ahlström, Håkan ^a   Caballero Corbalan, José ^a   Segersvärd, Ralf ^b   Permert, Johan ^b   Korsgren, Olle ^a   Carlsson, Per Ola ^a   Phillipson, Mia ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOXAN DIABETES MELLITUS; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOTRANSPLANTATION; BLOOD FLOW; CARDIOVASCULAR SYSTEM; CASE REPORT; CELL INTERACTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENGRAFTMENT; EXPERIMENTAL MODEL; FEMALE; FOREARM; HUMAN; HUMAN TISSUE; INTRADUCTAL PAPILLARY MUCINOUS TUMOR; MALE; MOUSE; MUSCLE TISSUE; NEUTROPENIA; NEUTROPHIL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PANCREAS ISLET TRANSPLANTATION; PANCREAS RESECTION; PANCREATICODUODENECTOMY; PRIORITY JOURNAL; REVASCULARIZATION; SKELETAL MUSCLE;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; BLOOD GLUCOSE; CELL SEPARATION; DIABETES MELLITUS, EXPERIMENTAL; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; LEUKOCYTE REDUCTION PROCEDURES; LEUKOCYTES; MALE; MICE; MICE, INBRED C57BL; MICE, NUDE; MUSCLE, SKELETAL; NEUTROPHILS; ORGAN CULTURE TECHNIQUES; REOPERATION; TRANSPLANTATION, AUTOLOGOUS; TRANSPLANTATION, HETEROTOPIC;

EID: 77957590676     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db10-0205     Document Type: Article

References (46)

1. Ryan EA, Paty BW, Senior PA, Bigam D, Alfadhli E, Kneteman NM, Lakey JR, Shapiro AM. Five-year follow-up after clinical islet transplantation. Diabetes 2005;54:2060-2069 (Pubitemid 40911269)
2. Mattsson G, Jansson L, Carlsson PO. Decreased vascular density in mouse pancreatic islets after transplantation. Diabetes 2002;51:1362-1366
3. Poitout V, Briaud I, Kelpe C, Hagman D. Gluco-lipotoxicity of the pancreatic beta cell. Ann Endocrinol (Paris) 2004;65:37-41
4. Bennet W, Sundberg B, Groth CG, Brendel MD, Brandhorst D, Brandhorst H, Bretzel RG, Elgue G, Larsson R, Nilsson B, Korsgren O. Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation? Diabetes 1999;48: 1907-1914
5. Moberg L, Johansson H, Lukinius A, Berne C, Foss A, Kallen R, Ostraat O, Salmela K, Tibell A, Tufveson G, Elgue G, Nilsson Ekdahl K, Korsgren O, Nilsson B. Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation. Lancet 2002;360:2039-2045
6. Redmon JB, Olson LK, Armstrong MB, Greene MJ, Robertson RP. Effects of tacrolimus (FK506) on human insulin gene expression, insulin mRNA levels, and insulin secretion in HIT-T15 cells. J Clin Invest 1996;98:2786-2793
7. Shapiro AM, Gallant HL, Hao EG, Lakey JR, McCready T, Rajotte RV, Yatscoff RW, Kneteman NM. The portal immunosuppressive storm: relevance to islet transplantation? Ther Drug Monit 2005;27:35-37
8. Lifson N, Kramlinger KG, Mayrand RR, Lender EJ. Blood flow to the rabbit pancreas with special reference to the islets of Langerhans. Gastroenterology 1980;79:466-473
9. Lifson N, Lassa CV, Dixit PK. Relation between blood flow and morphology in islet organ of rat pancreas. Am J Physiol 1985;249:E43-E48
10. Samols E, Stagner JI, Ewart RB, Marks V. The order of islet microvascular cellular perfusion is B-A-D in the perfused rat pancreas. J Clin Invest 1988;82:350-353
11. Stagner JI, Samols E. The vascular order of islet cellular perfusion in the human pancreas. Diabetes 1992;41:93-97
12. Stagner JI, Samols E, Bonner-Weir S. Beta - alpha - delta pancreatic islet cellular perfusion in dogs. Diabetes 1988;37:1715-1721
13. Stagner JI, Samols E, Koerker DJ, Goodner CJ. Perfusion with anti-insulin gamma globulin indicates a B to A to D cellular perfusion sequence in the pancreas of the rhesus monkey, Macaca mulatta. Pancreas 1992;7:26-29
14. Nyman LR, Wells KS, Head WS, McCaughey M, Ford E, Brissova M, Piston DW, Powers AC. Real-time, multidimensional in vivo imaging used to investigate blood flow in mouse pancreatic islets. J Clin Invest 2008;118: 3790-3797
15. Bonner-Weir S, Orci L. New perspectives on the microvasculature of the islets of Langerhans in the rat. Diabetes 1982;31:883-889
16. Lau J, Mattsson G, Carlsson C, Nyqvist D, Kohler M, Berggren PO, Jansson L, Carlsson PO. Implantation site-dependent dysfunction of transplanted pancreatic islets. Diabetes 2007;56:1544-1550
17. Lau J, Carlsson PO. Low revascularization of human islets when experimentally transplanted into the liver. Transplantation 2009;87:322-325
18. Tominaga Y, Uchida K, Haba T, Katayama A, Sato T, Hibi Y, Numano M, Tanaka Y, Inagaki H, Watanabe I, Hachisuka T, Takagi H. More than 1,000 cases of total parathyroidectomy with forearm autograft for renal hyperparathyroidism. Am J Kidney Dis 2001;38:S168-S171
19. Rafael E, Tibell A, Ryden M, Lundgren T, Savendahl L, Borgstrom B, Arnelo U, Isaksson B, Nilsson B, Korsgren O, Permert J. Intramuscular autotransplantation of pancreatic islets in a 7-year-old child: a 2-year follow-up. Am J Transplant 2008;8:458-462
20. Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL, Libby P, Weissleder R, Pittet MJ. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med 2007;204:3037-3047
21. Bryer SC, Fantuzzi G, Van Rooijen N, Koh TJ. Urokinase-type plasminogen activator plays essential roles in macrophage chemotaxis and skeletal muscle regeneration. J Immunol 2008;180:1179-1188
22. Bohman S, Andersson A, King A. No differences in efficacy between noncultured and cultured islets in reducing hyperglycemia in a nonvascularized islet graft model. Diabetes Technol Ther 2006;8:536-545
23. Goto M, Eich TM, Felldin M, Foss A, Kallen R, Salmela K, Tibell A, Tufveson G, Fujimori K, Engkvist M, Korsgren O. Refinement of the automated method for human islet isolation and presentation of a closed system for in vitro islet culture. Transplantation 2004;78:1367-1375
24. Phillipson M, Heit B, Colarusso P, Liu L, Ballantyne CM, Kubes P. Intraluminal crawling of neutrophils to emigration sites: a molecularly distinct process from adhesion in the recruitment cascade. J Exp Med 2006;203:2569-2575
25. Ahren B, Nobin A, Schersten B. Insulin and C-peptide secretory responses to glucagon in man: studies on the dose-response relationships. Acta Med Scand 1987;221:185-190
26. Speier S, Nyqvist D, Cabrera O, Yu J, Molano RD, Pileggi A, Moede T, Kohler M, Wilbertz J, Leibiger B, Ricordi C, Leibiger IB, Caicedo A, Berggren PO. Noninvasive in vivo imaging of pancreatic islet cell biology. Nat Med 2008;14:574-578
27. Nyqvist D, Kohler M, Wahlstedt H, Berggren PO. Donor islet endothelial cells participate in formation of functional vessels within pancreatic islet grafts. Diabetes 2005;54:2287-2293
28. Menger MD, Vajkoczy P, Beger C, Messmer K. Orientation of microvascular blood flow in pancreatic islet isografts. J Clin Invest 1994;93:2280-2285
29. Bonner-Weir S, O'Brien TD. Islets in type 2 diabetes: in honor of Dr. Robert C. Turner. Diabetes 2008;57:2899-2904
30. Cabrera O, Berman DM, Kenyon NS, Ricordi C, Berggren PO, Caicedo A. The unique cytoarchitecture of human pancreatic islets has implications for islet cell function. Proc Natl Acad Sci U S A 2006;103:2334-2339
31. Brissova M, Fowler MJ, Nicholson WE, Chu A, Hirshberg B, Harlan DM, Powers AC. Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy. J Histochem Cytochem 2005;53:1087-1097
32. Bosco D, Armanet M, Morel P, Niclauss N, Sgroi A, Muller YD, Giovannoni L, Parnaud G, Berney T: Unique arrangement of α- and β-cells in human islets of Langerhans. Diabetes 59:1202-1210
33. Weis J, Astrom G, Vinnars B, Wanders A, Ahlstrom H. Chemical-shift micro-imaging of subcutaneous lesions. MAGMA 2005;18:59-62
34. Markmann JF, Rosen M, Siegelman ES, Soulen MC, Deng S, Barker CF, Naji A. Magnetic resonance-defined periportal steatosis following intraportal islet transplantation: a functional footprint of islet graft survival? Diabetes 2003;52:1591-1594
35. Bhargava R, Senior PA, Ackerman TE, Ryan EA, Paty BW, Lakey JR, Shapiro AM. Prevalence of hepatic steatosis after islet transplantation and its relation to graft function. Diabetes 2004;53:1311-1317
36. Merani S, Toso C, Emamaullee J, Shapiro AM. Optimal implantation site for pancreatic islet transplantation. Br J Surg 2008;95:1449-1461
37. Stegall MD, Lafferty KJ, Kam I, Gill RG. Evidence of recurrent autoimmunity in human allogeneic islet transplantation. Transplantation 1996;61: 1272-1274
38. Axen KV, Pi-Sunyer FX. Long-term reversal of streptozotocin-induced diabetes in rats by intramuscular islet implantation. Transplantation 1981;31:439-441
39. Lund T, Korsgren O, Aursnes IA, Scholz H, Foss A. Sustained reversal of diabetes following islet transplantation to striated musculature in the rat. J Surg Res 2008;160:145-154
40. Prior BM, Yang HT, Terjung RL. What makes vessels grow with exercise training? J Appl Physiol 2004;97:1119-1128
41. Brown MD, Hudlicka O. Modulation of physiological angiogenesis in skeletal muscle by mechanical forces: involvement of VEGF and metalloproteinases. Angiogenesis 2003;6:1-14
42. Nozawa H, Chiu C, Hanahan D. Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis. Proc Natl Acad Sci U S A 2006;103:12493-12498
43. Girn HR, Ahilathirunayagam S, Mavor AI, Homer-Vanniasinkam S. Reperfusion syndrome: cellular mechanisms of microvascular dysfunction and potential therapeutic strategies. Vasc Endovascular Surg 2007;41:277-293
44. Weber C, Fraemohs L, Dejana E. The role of junctional adhesion molecules in vascular inflammation. Nat Rev Immunol 2007;7:467-477
45. Olerud J, Johansson M, Lawler J, Welsh N, Carlsson PO. Improved vascular engraftment and graft function after inhibition of the angiostatic factor thrombospondin-1 in mouse pancreatic islets. Diabetes 2008;57:1870-1877
46. Geissmann F, Jung S, Littman DR. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 2003;19: 71-82