Corneal morphogenesis during development and diseases

Eye and Contact Lens

Volumn 36, Issue 5, 2010, Pages 265-268

  Kao, Winston W Y ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Catenin; Cornea; Development; FGF7; Meibomian glands; Transgenic and knockout mice

Indexed keywords

BETA CATENIN; DOXYCYCLINE; KERATINOCYTE GROWTH FACTOR; MUTANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; CELL PROLIFERATION; CORNEA; CORNEA CELL; CORNEA EPITHELIUM; CROSS BREEDING; DISEASE COURSE; DNA MODIFICATION; EMBRYO DEVELOPMENT; EMBRYO INDUCTION; EPITHELIUM HYPERPLASIA; EYE CANCER; EYE DISEASE; EYE MALFORMATION; GENE EXPRESSION; GENE INDUCTION; GENE MUTATION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC LINE; LOXP SITE; MESENCHYME CELL; MORPHOGENESIS; MOUSE; NEURAL CREST CELL; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; TRANSGENE; TRANSGENIC ANIMAL; TRANSGENIC MOUSE; TRANSGENICS;

ANIMALS; BETA CATENIN; CORNEA; CORNEAL DISEASES; DISEASE MODELS, ANIMAL; EPITHELIUM, CORNEAL; HOMEOSTASIS; HYPERPLASIA; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MORPHOGENESIS; MUTATION; TRANSLOCATION, GENETIC;

EID: 77957577079     PISSN: 15422321     EISSN: None     Source Type: Journal    
DOI: 10.1097/ICL.0b013e3181ef0e00     Document Type: Review

References (19)

1. Kao WW, Liu C-Y. The use of transgenic and knock-out mice in the investigation of ocular surface cell biology. Ocul Surf 2003; 1: 5-19.
2. Kao WW, Xia Y, Liu C.Y., et al. Signaling pathways in morphogenesis of cornea and eyelid. Ocul Surf 2008; 6: 9-23.
3. Cvekl A, Tamm ER Anterior eye development and ocular mesenchyme: New insights from mouse models and human diseases. Bioessays 2004; 26: 374-386.
4. Tanifuji-Terai N., Terai K, Hayashi Y., et al. Expression of keratin 12 and maturation of corneal epithelium during development and postnatal growth. Invest Ophthalmol Vis Sci 2006; 47: 545-551.
5. Liu CY, Zhu G, Converse R.L., et al. Characterization and chromosomal localization of the cornea-specific murine keratin gene Krt1.12. J Biol Chem 1994; 269: 24627-24636.
6. Liu CY, Shiraishi A, Kao C.W., et al. The cloning of mouse keratocan cDNA and genomic DNA and the characterization of its expression during eye development. J Biol Chem 1998; 273: 22584-22588.
7. Byrne C, Tainsky M, Fuchs E. Programming gene expression in developing epidermis. Development 1994; 120: 2369-2383.
8. Liu CY, Zhu G, Westerhausen-Larson A, et al. Cornea-specific expression of K12 keratin during mouse development. Curr Eye Res 1993; 12: 963-974.
9. Chikama T, Hayashi Y, Liu C.Y., et al. Characterization of tetracycline-inducible bitransgenic Krt12rtTA/+/tet-O-LacZ mice. Invest Ophthalmol Vis Sci 2005; 46: 1966-1972.
10. Hay ED, Zuk A. Transformations between epithelium and mesenchyme: Normal, pathological, and experimentally induced. [Review]. Am J Kidney Dis 1995; 26: 678-690.
11. Hogan BL. Morphogenesis. Cell 1999; 96: 225-233.
12. Li DQ, Tseng SC Differential regulation of keratinocyte growth factor and hepatocyte growth factor/scatter factor by different cytokines in human corneal and limbal fibroblasts. J Cell Physiol 1997; 172: 361-372.
13. Tuli SS, Liu R, Chen C., et al. Immunohistochemical localization of EGF, TGF-alpha, TGF-beta, and their receptors in rat corneas during healing of excimer laser ablation. Curr Eye Res 2006; 31: 709-719.
14. Carrington LM, Albon J, Anderson I., et al. Differential regulation of key stages in early corneal wound healing by TGF-beta isoforms and their inhibitors. Invest Ophthalmol Vis Sci 2006; 47: 1886-1894.
15. Saika S, Ikeda K, Yamanaka O., et al. Loss of tumor necrosis factor alpha potentiates transforming growth factor beta-mediated pathogenic tissue response during wound healing. Am J Pathol 2006; 168: 1848-1860.
16. Liu H, Zhang J, Liu C.Y., et al. Cell therapy of congenital corneal diseases with umbilical mesenchymal stem cells: Lumican null mice. PLoS One 2010; 5: e10707.
17. Chikama T, Liu CY, Meij J.T., et al. Excess FGF-7 in corneal epithelium causes corneal intraepithelial neoplasia in young mice and epithelium hyperplasia in adult mice. Am J Pathol 2008; 172: 638-649.
18. Lovicu FJ, Kao WW, Overbeek PA Ectopic gland induction by lensspecific expression of keratinocyte growth factor (FGF-7) in transgenic mice. Mech Dev 1999; 88: 43-53.
19. Zhang Y, Call MK, Yeh L.K., et al. Aberrant expression of a beta-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea. J Cell Sci 2010; 123: 1285-1294.