Differential regulation of keratinocyte growth factor and hepatocyte growth factor/scatter factor by different cytokines in human corneal and limbal fibroblasts

Journal of Cellular Physiology

Volumn 172, Issue 3, 1997, Pages 361-372

  Li, De Quan ^a   Tseng, Scheffer C G ^a,b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; EPIDERMAL GROWTH FACTOR; GROWTH FACTOR; INTERLEUKIN 1BETA; KERATINOCYTE GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; CORNEA EPITHELIUM; FIBROBLAST; HUMAN; HUMAN CELL; MODULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; STEM CELL;

CELLS, CULTURED; CORNEA; CYTOKINES; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 7; FIBROBLAST GROWTH FACTORS; FIBROBLASTS; GENE EXPRESSION REGULATION; GROWTH INHIBITORS; GROWTH SUBSTANCES; HEPATOCYTE GROWTH FACTOR; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; LEUKEMIA INHIBITORY FACTOR; LIMBUS CORNEAE; LYMPHOKINES; PLATELET-DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030963969     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199709)172:3<361::AID-JCP10>3.0.CO;2-9     Document Type: Article

References (61)

1. Ansel, J.C., Tiesman, J.P., Olerud, J.E., Krueger, J.G., Krane, J.F., Tara, D.C., Shipley, G.D., Gilbertson, D., Usui, M.L., and Hart, C.E. (1993) Human keratinocytes are a major source of cutaneous plate-derived growth factor. J. Clin. Invest., 92:671-678.
2. Bates, S.E., Valverius, E.M., Ennis, B.W., Bronzert, D.A., Sheridan, J.P., Stampfer, M.R., Mendelsohn, J., Lippman, M.E., and Dickson, R.B. (1990) Expression of transforming growth factor-α/epidermal growth factor receptor pathway in normal breast epithelial cells. Endocrinology, 126:596-607.
3. Brauchle, M., Angermeyer, K., Hubner, G., and Werner, S. (1994) Large induction of keratinocyte factor expression by serum growth factors and pro-inflammatory cytokines in cultured fibroblasts. Oncogene, 9:3199-3204.
4. Chan, A.M.-L., Rubin, J.S., Bottaro, D.P., Hirschfield, D.W., Chedid, M., and Aaronson, S.A. (1991) Identification of a competitive HGF antagonist encoded by an alternative transcript. Science, 254:1382-1385.
5. Chedid, M., Rubin, J.S., Csaky, K.G., and Aaronson, S.A. (1994) Regulation of keratinocyte growth factor gene expression by interleukin 1. J. Biol. Chem., 269:10753-10757.
6. Cook, P.W., Pittelkow, M.R., and Shipley, G.D. (1991) Growth factor-independent proliferation of normal human neonatal keratinocytes: Production of autocrine- and paracrine-acting mitogenic factors. J. Cell. Physiol., 146:277-289.
7. Cotsarelis, G., Cheng, S.Z., Dong, G., Sun, T., and Lavker, R.M. (1989) Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells. Cell, 57:201-209.
8. Dinarello, C.A. (1989) Interleukin 1 and its biologically related cytokines. Adv. Immunol., 44:153-205.
9. Dlugosz, A.A., Cheng, C., Denning, M.F., Dempsey, P.J., Coffey, R.J., and Yuspa, S.H. (1994) Keratinocyte growth factor receptor ligands induce transforming growth factor a expression and activate the epidermal growth factor receptor signaling pathway in cultured epidermal keratinocytes. Cell Growth Diff., 5:1283-1292.
10. Ferriola, P.C., Robertson, A.T., Rusnak, D.W., Diaugustine, R., and Nettesheim, P. (1992) Epidermal growth factor dependence and TGF-α autocrine growth regulation in primary rat tracheal epithelial cells. J. Cell. Physiol., 152:302-309.
11. Finch, P.W., Rubin, J.S., Miki, T., Ron, D., and Aaronson, S.A. (1989) Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. Science, 245:752-755.
12. Gohda, E., Matsunaga, T., Kataoka, H., and Yamamoto, I. (1992) TGF-β is a potent inhibitor of hepatocyte growth factor secretion by human fibroblasts. Cell Biol. Int. Rep., 16:917-926.
13. Heldin, C., and Westermark, B. (1990) Platelet-derived growth factor: Mechanism of action and possible in vivo function. Cell Regul., 1:555-566.
14. Hogguist, K.A., Nett, M.A., Unanue, E.R., and Chaplin, D.D. (1991) Interleukin 1 is processed and released during apoptosis. Proc. Natl. Acad. Sci. USA, 88:8485-8489.
15. Khaw, P.T., Schultz, G.S., Mackay, S.L.D., Chegini, N., Rotatori, D.S., Adams, J.L., and Shimizu, R.W. (1992) Detection of transforming growth factor-α messager RNA and protein in human corneal epithelial cells. Invest. Ophthalmol. Vis. Sci., 33:3302-3306.
16. Li, D.Q., and Tseng, S.C.G. (1995) Three patterns of cytokine expression potentially involved in epithelial-fibroblast interactions of human ocular surface. J. Cell. Physiol., 163:61-79.
17. Li, D.Q., and Tseng, S.C.G. (1996) Differential regulation of cytokine and receptor transcript expression in human corneal and limbal fibroblasts by EGF, TGF-α, PDGF-BB and IL-1β. Invest. Ophthalmol. Vis. Sci., 37:2068-2080.
18. Mason, I.J., Fuller-Pace, F., Smith, R., and Dickson, C. (1994) FGF-7 (keratinocyte growth factor) expression during mouse development suggests roles in myogenesis, forebrain regionalisation and epithelial-mesenchymal interactions. Mech. Dev., 45:15-30.
19. Matsumoto, K.; Okazaki, H., and Nakamura, T. (1992a) Up-regulation of hepatocyte growth factor gene expression by interleukin-1 in human skin fibroblasts. Biochem. Biophys. Res. Commun., 188:235-243.
20. Matsumoto, K., Tajima, H., Okazaki, H., and Nakamura, T. (1992b) Negative regulation of hepatocyte growth factor gene expression in human lung fibroblasts and leukemic cells by transforming growth factor-β1 and glucocorticoids. J. Biol. Chem., 267:24917-24920.
21. Mead, J.E., and Fausto, N. (1989) Transforming growth factor a may be a physiological regulator of liver regeneration by means of an autocrine mechanism. Proc. Natl. Acad. Sci. USA, 126:1558-1562.
22. Miller, S.J., Lavker, R.M., and Sun, T. (1993) Keratinocyte stem cells of cornea, skin, and hair follicle: Common and distinguishing features. Semin. Dev. Biol., 4:217-240.
23. Montesano, R., Matsumoto, K., Nakamura, T., and Orci, L. (1991) Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell, 67:901-908.
24. Nagaike, M., Hirao, S., Tajima, H., Noji, S., Taniguchi, S., Matsumoto, K., and Nakamura, T. (1991) Renotropic functions of hepatocyte growth factor in renal regeneration after unilateral nephrectomy. J. Biol. Chem., 266:22781-22784.
25. Nakamura, T., Nishizawa, T., Hagiya, M., Seki, T., Shimonishi, M., Sugimuram, A., Tashiro, K., and Shimizu, S. (1989) Molecular cloning and expression of human hepatocyte growth factor. Nature, 342:440-443.
26. Nathan, C., and Sporn, M. (1991) Cytokines in context. J. Cell Biol., 113:981-986.
27. Noji, S., Tashiro, K., Koyama, E., Nohno, T., Ohyama, K., Taniguchi, S., and Nakamura, T. (1990) Expression of hepatocyte growth factor gene in endothelial cells and Kupffer cells of damaged rat livers, as revealed by in situ hybridization. Biochem. Biophys. Res. Commun., 173:42-47.
28. Ohashi, Y., Motokura, M., and Kinoshita, Y. (1989) Presence of epidermal growth factor in human tears. Invest. Ophthalmol. Vis. Sci., 30:1879-1882.
29. Panos, R.J., Rubin, J.S., Aaronson, S.A., and Mason, R.J. (1993) Keratinocyte growth factor and hepatocyte growth factor/scatter factor are heparin-binding growth factors for alveolar type II cells in fibroblast-conditioned medium. J. Clin. Invest., 92:969-977.
30. Pasquale, L.R., Dorman-Pease, M.E., Lutty, G.A., Quigley, H.A., and Jampel, H.D. (1993) Immunolocalization of TGF-β1, TGF-β2, and TGF-β3 in the anterior segment of the human eye. Invest. Ophthalmol. Vis. Sci., 34:23-30.
31. Pittelkow, M.R., Cook, C., Shipley, G.D., Derynck, R., and Coffey, R.J. (1993) Autonomous growth of human keratinocytes requires epidermal growth factor receptor occupancy. Cell Growth Diff., 4:513-521.
32. Rosen, E.M., Nigam, S.K., and Goldberg, I.D. (1994) Scatter factor and the c-Met receptor: A paradigm for mesenchymal/epithelial interaction. J. Cell Biol., 127:1783-1787.
33. Rubartelli, A., Cozzolino, F., Talio, M., and Sitia, R. (1990) A novel secretory pathway for interleukin-1β, a protein lacking a signal sequence. EMBO J., 9:1503-1510.
34. Rubin, J.S., Osada, H., Finch, P.W., Taylor, W.G., Rudikoff, S., and Aaronson, S.A. (1989) Purification and characterization of a newly identified growth factor specific for epithelial cells. Proc. Natl. Acad. Sci. USA, 86:802-806.
35. Rubin, J.S., Chan, A.M., Bottaro, D.P., Burgess, W.H., Taylor, W.G., Cech, A.C., Hirschfield, D.W., Wong, J., Miki, T., Finch, P.W., and Aaronson, S.A. (1991) A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor. Proc. Natl. Acad. Sci. USA, 88:415-419.
36. Rubin, J.S., Bottaro, D.P., and Aaronson, S.A. (1993) Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product. Biochim. Biophys. Acta, 1155:357-371.
37. Rubin, J. S., Bottaro, D.P., Chedid, M., Miki, T., Ron, D., Cheon, H., Taylor, W.G., Fortney, E., Sakata, H., Finch, P.W., and LaRochelle, W.J. (1995) Keratinocyte growth factor. Cell Biol. Int., 19:399-411.
38. Russell, E.S. (1979) Hereditary anemias of the mouse: a review for geneticists. Adv. Genet., 20:357-459.
39. Schermer, A., Galvin, S., and Sun, T. (1986) Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. J. Cell Biol., 103:49-62.
40. Seslar, S., Nakamura, T., and Byers, S.W. (1993) Regulation of fibroblast hepatocyte growth factor/scatter factor expression by human breast carcinoma cell lines and peptide growth factors. Cancer Res., 53:1233-1238.
41. Seslar, S., Nakamura, T., and Byers, S. (1995) Tumor-stroma interactions and stromal cell density regulate hepatocyte growth factor protein levels: A role for transforming growth factor-β activation. Endocrinology, 136:1945-1953.
42. Sonnenberg, E., Meyer, D., Weidner, K.M., and Birchmeier, C. (1993) Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelial during mouse development. J. Cell Biol., 123:223-235.
43. Soriano, J.V., Pepper, M.S., Nakamura, T., Orci, L., and Montesano, R. (1995) Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells. J. Cell Sci., 108:413-430.
44. Sotozono, C., Kinoshita, S., Kita, M., and Imanishi, J. (1994a) Paracrine role of keratinocyte growth factor in rabbit corneal epithelial cell growth. Exp. Eye Res., 59:385-392.
45. Sotozono, C., Kinoshita, S., Kita, M., and Imanishi, J. (1994b) Expression of keratinocyte growth factor mRNA in ex vivo and in vitro specimens of human cornea and conjunctiva. Jpn. J. Ophthalmol., 38:353-359.
46. Sotozono, C., Inatomi, T., Nakamura, M., and Kinoshita, S. (1995) Keratinocyte growth factor accelerates corneal epithelial wound healing in vivo. Invest. Ophthalmol. Vis. Sci., 36:1524-1529.
47. Sporn, M.B., Roberts, A.B., Wakersfield, I.M., and de Crombrugghe, B. (1987) Some recent advances in the chemistry and biology of transforming growth factor-β. J. Cell Biol., 105:1039-1045.
48. Stoker, M., and Perryman, M. (1985) An epithelial scatter factor released by embryonic fibroblasts. J. Cell Sci., 77:209-223.
49. Stoker, M., Gherardi, E., Perryman, M., and Gray, J. (1987) Scatter factor is a fibroblast-derived modulator of epithelial cell motility. Nature, 327:239-242.
50. Strain, A.J., McGuinness, G., Rubin, J.S., and Aaronson, S.A. (1994) Keratinocyte growth factor and fibroblast growth factor action on DNA synthesis in rat and human hepatocytes: Modulation by heparin. Exp. Cell Res., 210:253-259.
51. Tamura, M., Arakaki, N., Tsubouchi, H., Takada, H., and Daikuhara, Y. (1993) Enhancement of human hepatocyte growth factor production by interleukin-1α and -1β and tumor necrosis factor-α by fibroblasts in culture. J. Biol. Chem., 268:8140-8145.
52. Tseng, S.C.G. (1989) Concept and application of limbal stem cells. Eye, 3:141-157.
53. Tseng, S.C.G., Kruse, F.E., Merritt, J., and Li, D.Q. (1996) Comparison between serum-free and fibroblast-cocultured single-cell clonal culture systems: Evidence showing that epithelial anti-apoptotic activity is present in 3T3 fibroblast-conditioned media. Curr. Eye Res., 15:973-984.
54. van Setten, G.B., Viinikka, L., Tervo, T., Pesonen, K., Tarkkanen, A., and Perheentupa, J. (1989) Epidermal growth factor is a constant component of normal human tear fluid. Graefe's Arch. Clin. Exp. Ophthalmol., 227:184-187.
55. Werner, S., Peters, K.G., Longaker, M.T., Fuller Pace, F., Banda, M.J., and Williams, L.T. (1992) Large induction of keratinocyte growth factor expression in the dermis during wound healing. Proc. Natl. Acad. Sci. USA, 89:6896-6900.
56. Werner, S., Smola, H., Liao, X., Longaker, M.T., Krieg, T., Hofschneider, P.H., and Williams, L.T. (1994) The function of KGF in morphogenesis of epithelium and reepithelialization of wounds. Science, 266:819-822.
57. Wilson, S.E., Walker, J.W., Chwang, E.L., and He, Y. (1993) Hepatocyte growth factor, keratinocyte growth factor, their receptors, fibroblast growth factor receptor-2, and the cells of the cornea. Invest. Ophthalmol. Vis. Sci., 34:2544-2561.
58. Wilson, W.E., He, Y., Weng, J., Zieske, J.D., Jester, J.V., and Schultz, G.S. (1994) Effect of epidermal growth factor, hepatocyte growth factor, and keratinocyte growth factor, on proliferation, motility and differentiation of human corneal epithelial cells. Exp. Eye Res., 59:665-678.
59. Woolf, A.S., Kolatsi-Joannou, M., Hardman, P., Andermarcher, E., Moorby, C., Fine, L.G., Jat, P.S., Noble, M.D., and Gherardi, E. (1995) Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros. J. Cell Biol., 128:171-184.
60. Yan, G., Fukabori, Y., Nikolaropoulos, S., Wang, F., and McKeehan, W.L. (1992) Heparin-binding keratinocyte growth factor is a candidate stromal to epithelial cell andromedin. Mol. Endocrinol., 6:2123-2128.
61. Zarnegar, R., and Michalopoulos, G.K. (1995) The many faces of hepatocyte growth factor: From hepatopoiesis to hematopoiesis. J. Cell Biol., 129:1177-1180.