Worker exposures to nitrosamines in a rubber vehicle sealing plant

American Industrial Hygiene Association Journal

Volumn 57, Issue 10, 1996, Pages 918-923

  Reh, Beth Donovan ^a   Fajen, John M ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

nitrosamines; nitrosdimethylamine (NDMA); rubber vehicle sealing; salt bath curing process

Indexed keywords

NITROSAMINE; SEALANT;

AIR SAMPLING; ARTICLE; CHEMICAL ANALYSIS; CLINICAL ARTICLE; HUMAN; INDUSTRIAL WORKER; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; OPERATOR; RUBBER INDUSTRY;

EID: 0029797325     PISSN: 00028894     EISSN: None     Source Type: Journal    
DOI: 10.1080/15428119691014431     Document Type: Article

References (17)

1. Magee, P.N. and J.M. Barnes: The production of malignant primary hepatic tumors in the rat by feeding dimethylnitrosamine. Br. J. Cancer 10:114-122 (1956).
2. Preussman, R.: N-nitroso compounds. In Environemental Carcinogens. Selected Methods of Analysis, vol. 6. (IARC scientific pub. no. 45). Lyon, France: World Health Organization, International Agency for Research on Cancer, 1983. p. 4.
3. Bartsch, H. and R. Montesano: Relevance of N-nitrosamines to human cancer. Carcinogenesis 5(11):1381-1393 (1984).
4. National Institute for Occupational Safety and Health (NIOSH): N-nitroso Compounds in the Factory Environment, by D.P. Rounbehler and J.M. Fajen (DHHS/ NIOSH pub. no. 83-114). Cincinnati, OH: Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, NIOSH, 1983.
5. 6-methylguanosine in oesophageal DNA among individuals at high risk of oesophageal cancer. Int. J. Cancer 37:661-665 (1985).
6. 6-methylguanine in human DNA. In Methods for Detecting DNA Damaging Agents in Humans: Applications in Cancer Epidemiology and Prevention, H. Bartsch, K. Hemminki, and I.K. O'Neill, eds. (IARC scientific pub. no. 89). Lyon, France: International Agency for Research on Cancer, 1988. pp. 301-305.
7. 4-ethyldeoxythymidine in rats continuously exposed to diethylnitrosamine. Cancer Res. 47:1577-1581 (1987).
8. Deal, F.H., F.C. Richardson, and J.A. Swenberg: Dose response of hepatocyte replication in rats following continuous exposure to diethylnitrosamine. Cancer Res. 49:6985-6988 (1989).
9. 6-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Res. 50:3772-3780 (1990).
10. International Agency for Research on Cancer (IARC): IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans (ISBN 92-832-1411-0, ISSN 0250-9555). Lyon, France: World Health Organization, IARC, 1987.
11. National Toxicology Program: Sixth Annual Report on Carcinogens. Rockville, MD: Department of Health and Human Services, Public Health Service, National Toxicology Program, 1991.
12. 29 CFR 1910.1016.
13. National Institute for Occupational Safety and Health (NIOSH): NIOSH Recommendations for Occupational Safety and Health: Compendium of Policy Documents and Statements. (DHHS/NIOSH pub. no. 92-100) Cincinnati, OH: Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, NIOSH, 1992.
14. American Conference of Governmental Industrial Hygienists (ACGIH): 1994-1995 Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. Cincinnati, OH: ACGIH, 1994.
15. Bek, des BMA: German Technical Regulations for Hazardous Materials: N-nitrosamines (no. 552). German technical regulations for hazardous materials, Bundesarbeitsblatt, no. 6, 1994.
16. National Institute for Occupational Safety and Health (NIOSH): NIOSH Guide to Industrial Respiratory Protection. (DHHS/NIOSH pub. no. 87-116) Cincinnati, OH: Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, NIOSH, 1987.
17. 29 CFR 1910.134.