-
1
-
-
0024806396
-
Stability of protein pharmaceuticals
-
doi:10.1208/ps060104
-
Manning MC, Patel K Brochardt R. Stability of protein pharmaceuticals. Pharm Res. 1989; 6: 903-918. doi:10.1208/ps060104
-
(1989)
Pharm Res
, vol.6
, pp. 903-918
-
-
Manning, M.C.1
Patel, K.2
Brochardt, R.3
-
2
-
-
0025731293
-
Controlled delivery systems for proteins based on poly(lactic/glycolic acid) microspheres
-
doi:10.1023/A:1015841715384
-
Cohen S, Yoshioka T, Lucarelli M, Hwang LH, Langer R. Controlled delivery systems for proteins based on poly(lactic/glycolic acid) microspheres. Pharm Res.1991; 8: 713-720. doi:10.1023/A:1015841715384
-
(1991)
Pharm Res
, vol.8
, pp. 713-720
-
-
Cohen, S.1
Yoshioka, T.2
Lucarelli, M.3
Hwang, L.H.4
Langer, R.5
-
3
-
-
0023133637
-
Resorbable matetials of poly (L- lactide)
-
doi:10.1016/0142-9612(87)90034-2
-
Leenslag JW, Penning AJ, Bos RR, Rozema FR, Boering G. Resorbable matetials of poly (L- lactide). Biomaterials. 1978; 8: 70-73. doi:10.1016/0142-9612(87)90034-2
-
(1978)
Biomaterials
, vol.8
, pp. 70-73
-
-
Leenslag, J.W.1
Penning, A.J.2
Bos, R.R.3
Rozema, F.R.4
Boering, G.5
-
4
-
-
0034006495
-
Visual evidence of acidic environment within degrading poly(lactic-co-glycolic acid) (PLA) microspheres
-
doi:10.1023/A:1007582911958
-
Fu K, Pack DW, Klibanov AM, Langer R. Visual evidence of acidic environment within degrading poly(lactic-co-glycolic acid) (PLA) microspheres. Pharm Res. 2000; 17: 100-106. doi:10.1023/A:1007582911958
-
(2000)
Pharm Res
, vol.17
, pp. 100-106
-
-
Fu, K.1
Pack, D.W.2
Klibanov, A.M.3
Langer, R.4
-
5
-
-
0028205133
-
Biodegradable microspheres as controlled release tetanus toxoid delivery systems
-
doi:10.1016/0264-410X(94)90092-2
-
Alonso MJ, Gupta RK, Min C, Siber GR, Langer R. Biodegradable microspheres as controlled release tetanus toxoid delivery systems. Vaccine. 1994; 12: 299-306. doi:10.1016/0264-410X(94)90092-2
-
(1994)
Vaccine
, vol.12
, pp. 299-306
-
-
Alonso, M.J.1
Gupta, R.K.2
Min, C.3
Siber, G.R.4
Langer, R.5
-
6
-
-
4344596313
-
Identification of chemically modified peptide from poly(d,l-lactideco-glycolide) microspheres under in vitro release conditions
-
doi:10.1208/pt040450
-
Murty SB, Goodman J, Thanoo BC, DeLuca PP. Identification of chemically modified peptide from poly(d,l-lactideco-glycolide) microspheres under in vitro release conditions. AAPS PharmSciTech. 2003; 4: 392-405. doi:10.1208/pt040450
-
(2003)
AAPS PharmSciTech
, vol.4
, pp. 392-405
-
-
Murty, S.B.1
Goodman, J.2
Thanoo, B.C.3
de Luca, P.P.4
-
7
-
-
0034866534
-
Stabilization and controlled release of bovine serum albumin encapsulated in poly(D,L lactide) and poly(ethylene glycol) microsphere blends
-
doi:10.1023/A:1011009117586
-
Jiang W, Schwendeman SP. Stabilization and controlled release of bovine serum albumin encapsulated in poly(D,L lactide) and poly(ethylene glycol) microsphere blends. Pharm Res. 2001; 18: 878-885. doi:10.1023/A:1011009117586
-
(2001)
Pharm Res
, vol.18
, pp. 878-885
-
-
Jiang, W.1
Schwendeman, S.P.2
-
8
-
-
0033527924
-
Protein encapsulation within poly(ethylene glycol)-coated nanospheres. II. Controlled release properties
-
doi:10.1002/(SICI)1097-4636(19991205)47:3<388::AID-JBM14>3.0.CO;2-V
-
Quellec P, Gref R, Dellacherie E, Sommer F, Tran MD, Alonso MJ. Protein encapsulation within poly(ethylene glycol)-coated nanospheres. II. Controlled release properties. J Biomed Mater Res.1999; 47: 388-395. doi:10.1002/(SICI)1097-4636(19991205)47:3<388::AID-JBM14>3.0.CO;2-V
-
(1999)
J Biomed Mater Res
, vol.47
, pp. 388-395
-
-
Quellec, P.1
Gref, R.2
Dellacherie, E.3
Sommer, F.4
Tran, M.D.5
Alonso, M.J.6
-
9
-
-
0343777295
-
Biodegradable poly(D,L-lactic acid)-poly(ethylene glycol)- monomethyl ether diblock copolymers: Structures and surface properties relevant to their use as biomaterials
-
doi:10.1016/S0142-9612(00)00103-4
-
Lucke A, Teßmar J, Schnell E, Schmeer G, Göpferich A. Biodegradable poly(D,L-lactic acid)-poly(ethylene glycol)- monomethyl ether diblock copolymers: structures and surface properties relevant to their use as biomaterials. Biomaterials. 2000; 21: 2361-2370. doi:10.1016/S0142-9612(00)00103-4
-
(2000)
Biomaterials
, vol.21
, pp. 2361-2370
-
-
Lucke, A.1
Teßmar, J.2
Schnell, E.3
Schmeer, G.4
Göpferich, A.5
-
10
-
-
0028116078
-
Surface modification of poly- (lactide-co-glycolide) nanospheres by biodegradable poly (lactide)-poly(ethylene glycol) copolymers
-
doi:10.1023/A:1018931820564
-
Stolnik S, Dunn SE, Garnett MC, Davies MC, Coombes AG, Taylor DC, Irving MP, Purkiss SC, Tadros TF, Davis SS, Illum L. Surface modification of poly- (lactide-co-glycolide) nanospheres by biodegradable poly (lactide)-poly(ethylene glycol) copolymers. Pharm Res. 1994; 11: 1800-1808. doi:10.1023/A:1018931820564
-
(1994)
Pharm Res
, vol.11
, pp. 1800-1808
-
-
Stolnik, S.1
Dunn, S.E.2
Garnett, M.C.3
Davies, M.C.4
Coombes, A.G.5
Taylor, D.C.6
Irving, M.P.7
Purkiss, S.C.8
Tadros, T.F.9
Davis, S.S.10
Illum, L.11
-
11
-
-
0004103464
-
-
In: Kluwer Academic Publishers, London
-
Brange J. In: Stability of insulin. Kluwer Academic Publishers, London,1974: pp11.
-
(1974)
Stability of insulin
, pp. 11
-
-
Brange, J.1
-
12
-
-
23944513080
-
Stability of insulin during the erosion of poly(lactic acid) and poly(lactic-co-glycolic acid) microspheres
-
doi:10.1016/j.jconrel.2005.02.025
-
Ibrahim MA, Ismail A, Fetouh MI, Göpferich A. Stability of insulin during the erosion of poly(lactic acid) and poly(lactic-co-glycolic acid) microspheres. J Control Release. 2005; 106: 241-252. doi:10.1016/j.jconrel.2005.02.025
-
(2005)
J Control Release
, vol.106
, pp. 241-252
-
-
Ibrahim, M.A.1
Ismail, A.2
Fetouh, M.I.3
Göpferich, A.4
-
13
-
-
0028321707
-
Dose and load studies for subcutaneous and oral delivery of poly(lactide-co-glycolide) microspheres containing ovalbumin
-
doi:10.1023/A:1018987404751
-
Uchida T, Martin S, Foster TP, Wardley RC, Grimm S. Dose and load studies for subcutaneous and oral delivery of poly(lactide-co-glycolide) microspheres containing ovalbumin. Pharm Res. 1994; 11: 1009-1015. doi:10.1023/A:1018987404751
-
(1994)
Pharm Res
, vol.11
, pp. 1009-1015
-
-
Uchida, T.1
Martin, S.2
Foster, T.P.3
Wardley, R.C.4
Grimm, S.5
-
14
-
-
0032078351
-
Protein encapsulation and release from poly(lactide-co-glycolide) microspheres: Effect of the protein and polymer properties and of the co-encapsulation of surfactants
-
doi:10.1016/S0939-6411(98)00011-3
-
Blanco D, Alonso MJ. Protein encapsulation and release from poly(lactide-co-glycolide) microspheres: effect of the protein and polymer properties and of the co-encapsulation of surfactants. Eur J Pharm Biopharm. 1998; 45: 285-294. doi:10.1016/S0939-6411(98)00011-3
-
(1998)
Eur J Pharm Biopharm
, vol.45
, pp. 285-294
-
-
Blanco, D.1
Alonso, M.J.2
-
15
-
-
0034602127
-
Influence of coencapsulation of different non-ionic surfactants on the properties of PLGA insulin-loaded microspheres
-
doi:10.1016/S0168-3659(00)00315-1
-
De Rosa G, Iommelli R, La Rotonda MI, Miro A, Quaglia F. Influence of coencapsulation of different non-ionic surfactants on the properties of PLGA insulin-loaded microspheres. J Control Release. 2000; 69: 283-295. doi:10.1016/S0168-3659(00)00315-1
-
(2000)
J Control Release
, vol.69
, pp. 283-295
-
-
De Rosa, G.1
Iommelli, R.2
La Rotonda, M.I.3
Miro, A.4
Quaglia, F.5
-
16
-
-
0030955276
-
Preparation and characterization of polylactic acid microspheres containing bovine insulin by a w/o/w emulsion solvent evaporation method
-
PMid:9332006
-
Uchida T, Nagareya N, Sakakibara S, Konishi Y, Nakai A, Nishikata M, Matsuyama K, Yoshida K. Preparation and characterization of polylactic acid microspheres containing bovine insulin by a w/o/w emulsion solvent evaporation method. Chem Pharm Bull. 1997; 45: 1539-1543. PMid:9332006
-
(1997)
Chem Pharm Bull
, vol.45
, pp. 1539-1543
-
-
Uchida, T.1
Nagareya, N.2
Sakakibara, S.3
Konishi, Y.4
Nakai, A.5
Nishikata, M.6
Matsuyama, K.7
Yoshida, K.8
-
17
-
-
0345084475
-
A new preparation method for protein loaded poly (d,l-lactic-co-glycolic acid) microspheres and protein release mechanism study
-
doi:10.1016/S0168-3659(98)00050-9
-
Park TG, Lee HY, Nam YS. A new preparation method for protein loaded poly (d,l-lactic-co-glycolic acid) microspheres and protein release mechanism study. J Control Release. 1998; 55: 181-191. doi:10.1016/S0168-3659(98)00050-9
-
(1998)
J Control Release
, vol.55
, pp. 181-191
-
-
Park, T.G.1
Lee, H.Y.2
Nam, Y.S.3
-
18
-
-
0032484235
-
NGF release from poly (d,l-lactide-coglycolide) microspheres. Effect of some formulation parameters on encapsulated NGF stability
-
doi:10.1016/S0168-3659(98)00086-8
-
Péan JM, Venier-Julienne MC, Boury F, Menei P, Denizot B, Benoit JP. NGF release from poly (d,l-lactide-coglycolide) microspheres. Effect of some formulation parameters on encapsulated NGF stability. J Control Release. 1998; 56: 175-187. doi:10.1016/S0168-3659(98)00086-8
-
(1998)
J Control Release
, vol.56
, pp. 175-187
-
-
Péan, J.M.1
Venier-Julienne, M.C.2
Boury, F.3
Menei, P.4
Denizot, B.5
Benoit, J.P.6
-
19
-
-
0027093737
-
Chemical stability of insulin. 4. Mechanisms and kinetics of chemical transformations in pharmaceutical formulation
-
PMid:1294186
-
Brange J. Chemical stability of insulin. 4. Mechanisms and kinetics of chemical transformations in pharmaceutical formulation. Acta Pharm Nord. 1992; 4: 209-222. PMid:1294186
-
(1992)
Acta Pharm Nord
, vol.4
, pp. 209-222
-
-
Brange, J.1
-
20
-
-
0032863592
-
Why does PEG 400 co-encapsulation improve NGF stability and release from PLGA biodegra dable microspheres?
-
doi:10.1023/A:1014818118224
-
Péan JM, Boury F, Venier-Julienne MC, Menei P, Proust JE, Benoit JP. Why does PEG 400 co-encapsulation improve NGF stability and release from PLGA biodegra dable microspheres? Pharm Res. 1999; 16: 1294-1299. doi:10.1023/A:1014818118224
-
(1999)
Pharm Res
, vol.16
, pp. 1294-1299
-
-
Péan, J.M.1
Boury, F.2
Venier-Julienne, M.C.3
Menei, P.4
Proust, J.E.5
Benoit, J.P.6
-
21
-
-
0033527144
-
Modulation of marrow stromal cell function using poly(D,L- lactic acid)-block-poly(ethylene glycol)-mono methylether surfaces
-
doi:10.1002/(SICI)1097-4636(19990905)46:3<390::AID-JBM12>3.0.CO;2-N
-
Göpferich A, Peter SJ, Lucke A, Lu L, Mikos AG. Modulation of marrow stromal cell function using poly(D,L- lactic acid)-block-poly(ethylene glycol)-mono methylether surfaces. J Biomed Mater Res. 1999; 46: 390-398. doi:10.1002/(SICI)1097-4636(19990905)46:3<390::AID-JBM12>3.0.CO;2-N
-
(1999)
J Biomed Mater Res
, vol.46
, pp. 390-398
-
-
Göpferich, A.1
Peter, S.J.2
Lucke, A.3
Lu, L.4
Mikos, A.G.5
-
22
-
-
0034738791
-
Influence of process parameters on the protein stability encapsulated in poly-DL-lactide-poly(ethylene glycol) microspheres
-
doi:10.1016/S0168-3659(00)00235-2
-
Li X, Zhang Y, Yan R, Jia W, Yuan M, Deng X, Huang Z. Influence of process parameters on the protein stability encapsulated in poly-DL-lactide-poly(ethylene glycol) microspheres. J Control Release. 2000; 68: 41-52. doi:10.1016/S0168-3659(00)00235-2
-
(2000)
J Control Release
, vol.68
, pp. 41-52
-
-
Li, X.1
Zhang, Y.2
Yan, R.3
Jia, W.4
Yuan, M.5
Deng, X.6
Huang, Z.7
-
23
-
-
0037161319
-
The effect of poly(ethylene glycol)-poly(D,L-lactic acid) diblock copolymers on peptide acylation
-
doi:10.1016/S0168-3659(02)00020-2
-
Lucke A, Fustella E, Teßmara J, Gazzaniga A, Göpferich A. The effect of poly(ethylene glycol)-poly(D,L-lactic acid) diblock copolymers on peptide acylation. J Control Release. 2002; 80: 157-168. doi:10.1016/S0168-3659(02)00020-2
-
(2002)
J Control Release
, vol.80
, pp. 157-168
-
-
Lucke, A.1
Fustella, E.2
Teßmara, J.3
Gazzaniga, A.4
Göpferich, A.5
-
24
-
-
0033026897
-
pH and osmotic pressure inside biodegradable micospheres during erosion
-
doi:10.1023/A:1018822002353
-
Brunner A, Mäder K, Göpfrerich A. pH and osmotic pressure inside biodegradable micospheres during erosion. Pharm Res. 1999; 16: 847-853. doi:10.1023/A:1018822002353
-
(1999)
Pharm Res
, vol.16
, pp. 847-853
-
-
Brunner, A.1
Mäder, K.2
Göpfrerich, A.3
|