The Effect of Human Umbilical Cord Blood Cells on Survival and Cytokine Production by Post-Ischemic Astrocytes in Vitro

Stem Cell Reviews and Reports

Volumn 6, Issue 4, 2010, Pages 523-531

  Jiang, Lixian ^a,b   Saporta, Samuel ^a,b   Chen, Ning ^a,b   Sanberg, Cyndy Davis ^c   Sanberg, Paul ^a,b   Willing, Alison ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c Saneron CCEL Therapeutics Inc   (United States)

Author keywords

B cell; Cytokines; Hypoxia; In vitro; Macrophages; Monocytes; T cell

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6;

ANIMAL; ANOXIA; ARTICLE; ASTROCYTE; BRAIN ISCHEMIA; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; FETUS BLOOD; HUMAN; METABOLISM; PHYSIOLOGY; RAT;

ANIMALS; ANOXIA; ASTROCYTES; BRAIN ISCHEMIA; CELL SURVIVAL; CELLS, CULTURED; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FETAL BLOOD; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-1BETA; INTERLEUKIN-6; RATS;

RATTUS;

EID: 77957352498     PISSN: 15508943     EISSN: 15586804     Source Type: Journal    
DOI: 10.1007/s12015-010-9174-x     Document Type: Article

References (54)

1. Newcomb, J. D., Ajmo, C. T., Davis Sanberg, C., Sanberg, P. R., Pennypacker, K. R., & Willing, A. E. (2006). Timing of cord blood treatment after experimental stroke determines therapeutic efficacy. Cell Transplantation, 15, 213-223.
2. Vendrame, M., Cassady, C. J., Newcomb, J., et al. (2004). Infusion of human umbilical cord blood cells in a rat model of stroke dose-dependently rescues behavioral deficits and reduces infarct volume. Stroke, 35, 2390-2395.
3. Willing, A. E., Lixian, J., Milliken, M., et al. (2003). Intravenous versus intrastriatal cord blood administration in a rodent model of stroke. Journal of Neuroscience Research, 73, 296-307.
4. Borlongan, C. V., Hadman, M., Davis Sanberg, C., & Sanberg, P. R. (2004). CNS entry of peripherally injected umbilical cord blood cells is not required for neuroprotection in stroke. Stroke, 35, 2385-2389.
5. Vendrame, M., Gemma, C., de Mesquita, D., et al. (2005). Anti-inflammatory effects of human cord blood cells in a rat model of stroke. Stem Cells and Development, 14, 595-604.
6. Hall, A. A., Leonardo, C. C., Collier, L. A., Rowe, D. D., Willing, A. E., & Pennypacker, K. R. (2009). Delayed treatments for stroke influence neuronal death in rat organotypic slice cultures subjected to oxygen glucose deprivation. Neuroscience, 164, 470-477.
7. Hall, A., Guyer, A., Leonardo, C., et al. (2009). Umbilical cord blood cells directly suppress ischemic oligodendrocyte cell death. Journal of Neuroscience Research, 87, 333-341.
8. Bracci-Laudiero, L., Celestino, D., Starace, G., et al. (2003). CD34-positive cells in human umbilical cord blood express nerve growth factor and its specific receptor TrkA. Journal of Neuroimmunology, 136, 130-139.
9. Arien-Zakay, H., Lecht, S., Bercu, M. M., et al. (2009). Neuroprotection by cord blood neural progenitors involves antioxidants, neurotrophic and angiogenic factors. Experimental Neurology, 216, 83-94.
10. Fan, C.-G., Zhang, Q.-J., Tang, F.-W., Han, Z.-B., Wang, G.-S., & Han, Z.-C. (2005). Human umbilical cord blood cells express neurotrophic factors. Neuroscience Letters, 380, 322-325.
11. Zwart, I., Hill, A. J., Al-Allaf, F., et al. (2009). Umbilical cord blood mesenchymal stromal cells are neuroprotective and promote regeneration in a rat optic tract model. Experimental Neurology, 216, 439-448.
12. Neuhoff, S., Moers, J., Rieks, M., et al. (2007). Proliferation, differentiation, and cytokine secretion of human umbilical cord blood-derived mononuclear cells in vitro. Experimental Hematology, 35, 1119-1131.
13. McGuckin, C. P., Forraz, N., Allouard, Q., & Pettengell, R. (2004). Umbilical cord blood stem cells can expand hematopoietic and neuroglial progenitors in vitro. Experimental Cell Research, 295, 350-359.
14. Hau, S., Reich, D. M., Scholz, M., et al. (2008). Evidence for neuroprotective properties of human umbilical cord blood cells after neuronal hypoxia in vitro. BMC Neuroscience, 9, 30.
15. Jiang, L., Womble, T., Saporta, S., et al. (2010). Human umbilical cord blood cells depress the microglial inflammatory response in vitro. Stem Cells and Development, 19, 221-227.
16. Ehrlich, L. C., Peterson, P. K., & Hu, S. (1999). Interleukin (IL)-1beta-mediated apoptosis of human astrocytes. NeuroReport, 10, 1849-1852.
17. Suk, K., Lee, J., Hur, J., et al. (2001). Activation-induced cell death of rat astrocytes. Brain Research, 900, 342-347.
18. Niu, F., Zhang, X., Chang, L., et al. (2009). Trichostatin A enhances OGD-astrocyte viability by inhibiting inflammatory reaction mediated by NF-κB. Brain Research Bulletin, 78, 342-346.
19. Schultz, C., Reiss, I., Bucsky, P., et al. (2000). Maturational changes of lymphocyte surface antigens in human blood: comparison between fetuses, neonates and adults. Biology of the Neonate, 78, 77-82.
20. Harris, D. P., Haynes, L., Sayles, P. C., et al. (2000). Reciprocal regulation of polarized cytokine production by effector B and T cells. Nature Immunology, 1, 475-482.
21. Yu, P., Wang, Y., Chin, R. K., et al. (2002). B cells control the migration of a subset of dendritic cells into B cell follicles via CXC chemokine ligand 13 in a lymphotoxin-dependent fashion. Journal of Immunology, 168, 5117-5123.
22. Fogelstrand, L., Hulthe, J., Hulten, L. M., Wiklund, O., & Fagerberg, B. (2004). Monocytic expression of CD14 and CD18, circulating adhesion molecules and inflammatory markers in women with diabetes mellitus and impaired glucose tolerance. Diabetologia, 47, 1948-1952.
23. Anderson, D. C., Schmalstieg, F. C., Kohl, S., et al. (1984). Abnormalities of polymorphonuclear leukocyte function associated with a heritable deficiency of a high molecular weight surface glycoprotein (gp138): common relationship to diminished cell adherence. The Journal of Clinical Investigation, 74, 536-551.
24. Kaufman, D., Kilpatrick, L., Hudson, R. G., et al. (1999). Decreased superoxide production, degranulation, tumor necrosis factor alpha secretion, and CD11b/CD18 receptor expression by adherent monocytes from preterm infants. Clinical and Diagnostic Laboratory Immunology, 6, 525-529.
25. Jiang, Q., Azuma, E., Hirayama, M., et al. (2001). Functional immaturity of cord blood monocytes as detected by impaired response to hepatocyte growth factor. Pediatrics International, 43, 334-339.
26. Pranke, P., Failace, R. R., Allebrandt, W. F., Steibel, G., Schmidt, F., & Nardi, N. B. (2001). Hematologic and immunophenotypic characterization of human umbilical cord blood. Acta Haematologica, 105, 71-76.
27. Rainsford, E., & Reen, D. J. (2002). Interleukin 10, produced in abundance by human newborn t cells, may be the regulator of increased tolerance associated with cord blood stem cell transplantation. British Journal Haematology, 116, 702-709.
28. Juretic, E., Gagro, A., Vukelic, V., & Petrovecki, M. (2004). Maternal and neonatal lymphocyte subpopulations at delivery and 3 days postpartum: Increased coexpression of cd45 isoforms. American Journal of Reproductive Immunology, 52, 1-7.
29. De Paoli, P., Battistin, S., & Santini, G. F. (1988). Age-related changes in human lymphocyte subsets: progressive reduction of the CD4 CD45r (suppressor inducer) population. Clinical Immunology and Immunopathology, 48, 290-296.
30. Xia, D., Hao, S., & Xiang, J. (2006). CD8+ cytotoxic T-APC stimulate central memory CD8+ T cell responses via acquired peptide-mhc class I complexes and CD80 costimulation, and IL-2 secretion. Journal of Immunology, 177, 2976-2984.
31. Hombach, A., Kohler, H., Rappl, G., & Abken, H. (2006). Human CD4+ T cells lyse target cells via granzyme/perforin upon circumvention of mhc class ii restriction by an antibody-like immunoreceptor. Journal of Immunology, 177, 5668-5675.
32. Diamond, A. S., & Gill, R. G. (2000). An essential contribution by IFN-gamma to CD8+ T cell-mediated rejection of pancreatic islet allografts. Journal of Immunology, 165, 247-255.
33. Cocchi, F., DeVico, A. L., Garzino-Demo, A., Arya, S. K., Gallo, R. C., & Lusso, P. (1995). Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV- suppressive factors produced by CD8+ T cells. Science, 270, 1811-1815.
34. Kim, J. J., Nottingham, L. K., & Sin, J. I. (1998). CD8 positive T cells influence antigen-specific immune responses through the expression of chemokines. The Journal of Clinical Investigation, 102, 1112-1124.
35. Zigova, T., Willing, A. E., Saporta, S., et al. (2001). Apoptosis in cultured hNT neurons. Developmental Brain Research, 127, 63-70.
36. Chen, Y., & Swanson, R. A. (2003). Astrocytes and brain injury. Journal of Cerebral Blood Flow and Metabolism, 23, 137-149.
37. Gao, Q., Li, Y., & Chopp, M. (2005). Bone marrow stromal cells increase astrocyte survival via upregulation of phosphinoside 3-kinase/threonine protein kinase and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways and stimulate astrocyte trophic factor gene expression after anaerobic insult. Neuroscience, 136, 123-134.
38. Benavides, A., Pastor, D., Santos, P., Tranque, P. A., & Calvo, S. (2005). CHOP plays a pivotal role in the astrocyte death induced by oxygen and glucose deprivation. Glia, 52, 261-275.
39. Schobitz, B., De Kloet, E. R., & Holsboer, F. (1994). Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain. Progress in Neurobiology, 44, 397-432.
40. Colasanti, M., Ramacci, M. T., Foresta, P., & Lauro, G. M. (1991). Different in vitro response to rIL-1 beta of newborn and adult rat astroglia. International Journal of Developmental Neuroscience, 9, 501-507.
41. Goswami, S., Gupta, A., & Sharma, S. K. (1998). Interleukin-6-mediated autocrine growth promotion in human glioblastoma multiforme cell line U87MG. Journal of Neurochemistry, 71, 1837-1845.
42. Hama, T., Kushima, Y., Miyamoto, M., Kubota, M., Takei, N., & Hatanaka, H. (1991). Interleukin-6 improves the survival of mesencephalic catecholaminergic and septal cholinergic neurons from postnatal, two-week-old rats in cultures. Neuroscience, 40, 445-452.
43. Yamada, M., & Hatanaka, H. (1994). Interleukin-6 protects cultured rat hippocampal neurons against glutamate-induced cell death. Brain Research, 643, 173-180.
44. Campbell, I. L., Abraham, C. R., Masliah, E., et al. (1993). Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6. Proceedings of the National Academy of Sciences of the United States of America, 90, 10061-10065.
45. Heyser, C. J., Masliah, E., Samimi, A., Campbell, I. L., & Gold, L. H. (1997). Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain. Proceedings of the National Academy of Sciences of the United States of America, 94, 1500-1505.
46. Penkowa, M., Molinero, A., Carrasco, J., & Hidalgo, J. (2001). Interleukin-6 deficiency reduces the brain inflammatory response and increases oxidative stress and neurodegeneration after kainic acid-induced seizures. Neuroscience Letters, 102, 805-818.
47. Kotake, Y., Sang, H., Tabatabaie, T., Wallis, G. L., Moore, D. R., & Stewart, C. A. (2002). Interleukin-10 overexpression mediates phenyl-n-tert-butyl nitrone protection from endotoxemia. Shock, 17, 210-216.
48. Dokka, S., Shi, X., Leonard, S., Wang, L., Castranova, V., & Rojanasakul, Y. (2001). Interleukin-10-mediated inhibition of free radical generation in macrophages. American Journal of Physiology. Lung Cellular and Molecular Physiology, 280, L1196-L1202.
49. Spera, P. A., Ellison, J. A., & Feuerstein, G. Z. (1998). IL-10 reduces rat brain injury following focal stroke. Neuroscience Letters, 251, 189-192.
50. Fuchs, A. C., Granowitz, E. V., Shapiro, L., et al. (1996). Clinical, hematologic and immunologic effects of interleukin-10 in humans. Journal of Clinical Immunology, 16, 291-303.
51. Davies, C. A., Loddick, S. A., Toulmond, S., Stroemer, R. P., Hunt, J., & Rothwell, N. J. (1999). The progression and topographic distribution of interleukin-1beta expression after permanent middle cerebral artery occlusion in the rat. Journal of Cerebral Blood Flow and Metabolism, 19, 87-98.
52. Lee, S. C., Liu, W., Dickson, D. W., Brosnan, C. F., & Berman, J. W. (1993). Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta. Journal of Immunology, 150, 2659-2667.
53. Tomozawa, Y., Inoue, T., & Satoh, M. (1995). Expression of type I interleukin-1 receptor mRNA and its regulation in cultured astrocytes. Neuroscience Letters, 195, 57-60.
54. Liu, M., Hurn, P. D., Roselli, C. E., & Alkayed, N. J. (2007). Role of p450 aromatase in sex-specific astrocytic cell death. Journal of Cerebral Blood Flow and Metabolism, 27, 135-141.