PrPC, the cellular isoform of the human prion protein, is a novel biomarker of HIV-associated neurocognitive impairment and mediates neuroinflammation

American Journal of Pathology

Volumn 177, Issue 4, 2010, Pages 1848-1860

  Roberts, Toni K ^a   Eugenin, Eliseo A ^a   Morgello, Susan ^b   Clements, Janice E ^c   Zink, M Christine ^b   Berman, Joan W ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b Mt Sinai Liver Cancer Program   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; PRION PROTEIN; RECOMBINANT PROTEIN;

ADULT; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; COGNITIVE DEFECT; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENCEPHALITIS; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; MACACA; MALE; NONHUMAN; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN SECRETION; ANIMAL; BRAIN DISEASE; CELL CULTURE; CYTOLOGY; DISEASE COURSE; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; INFLAMMATION; MACACA NEMESTRINA; MACROPHAGE; METABOLISM; MIDDLE AGED; MONOCYTE; NERVE CELL; PATHOGENICITY; PATHOLOGY; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; VIROLOGY;

ADULT; ANIMALS; ASTROCYTES; BIOLOGICAL MARKERS; BRAIN DISEASES; CELLS, CULTURED; CHEMOKINE CCL2; COGNITION DISORDERS; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; IMMUNOENZYME TECHNIQUES; INFLAMMATION; MACACA NEMESTRINA; MACROPHAGES; MALE; MIDDLE AGED; MONOCYTES; NEURONS; PRPC PROTEINS; RECOMBINANT PROTEINS; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 77957345682     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.091006     Document Type: Article

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