Generation of a human anti-tumor necrosis factor-α monoclonal antibody by in vitro immunization with a multiple antigen peptide

Bioscience, Biotechnology and Biochemistry

Volumn 74, Issue 9, 2010, Pages 1836-1840

  Fujiki, Tsukasa ^a,b   Tsun, Atsuji ^a   Matsumoto, Shin Ei ^a   Yamashita, Makiko ^a   Teruya, Kiichiro ^a   Shirahata, Sanetaka ^a   Katakura, Yoshinori ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b NAGASAKI INTERNATIONAL UNIVERSITY   (Japan)

Author keywords

Human monoclonal antibody; In vitro immunization; Multiple antigen peptide

Indexed keywords

ANTI-TUMORS; ANTIBODY GENES; HUMAN IGG; HUMAN MONOCLONAL ANTIBODY; HUMAN PERIPHERAL BLOOD; IMMUNE RESPONSE; IN-VITRO; MULTIPLE ANTIGEN PEPTIDES; PHAGE-DISPLAY; TUMOR NECROSIS FACTORS;

ALLERGIES; GENES; GLYCOPROTEINS; IMMUNIZATION; MACROPHAGES; MERGERS AND ACQUISITIONS; MONOCLONAL ANTIBODIES; PEPTIDES; SURFACE PLASMON RESONANCE; TUMORS;

ANTIGENS;

ANTIGEN; MONOCLONAL ANTIBODY; PEPTIDE; TUMOR NECROSIS FACTOR ALPHA;

ANTIBODY SPECIFICITY; ARTICLE; BIOSYNTHESIS; GENETIC ENGINEERING; GENETICS; HUMAN; IMMUNIZATION; IMMUNOGLOBULIN CONSTANT REGION; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; METHODOLOGY; MONONUCLEAR CELL;

ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTIGENS; GENETIC ENGINEERING; HUMANS; IMMUNIZATION; IMMUNOGLOBULIN CONSTANT REGIONS; IMMUNOGLOBULIN VARIABLE REGION; LEUKOCYTES, MONONUCLEAR; PEPTIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77957345197     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.100243     Document Type: Article

References (14)

1. Co MS and Queen C, Nature, 351, 501-502 (1991).
2. Barbas CF 3rd, Kang AS, Lerner RA, and Benkovic SJ, Proc. Natl. Acad. Sci. USA, 88, 7978-7982 (1991).
3. Marks JD, Hoogenboom HR, Bonnert TP, McCafferty J, Griffiths AD, and Winter G, J. Mot Biol, 222, 581-597 (1991).
4. Fishwild DM, O'Donnell SL, Bengoechea T, Hudson DV, Harding F, Bernhard SL, Jones D, Kay RM, Higgins KM, Schramm SR, and Lonberg N, Nat. Biotechnol, 14, 845-851 (1996).
5. Vaughan TJ, Williams AJ, Pritchard K, Osbourn JK, Pope AR, Earnshaw JC, McCafferty J, Hodits RA, Wilton J, and Johnson KS, Nat. Biotechnol, 14, 309-314 (1996).
6. Ichikawa A, Katakura Y, Teruya K, Hashizume S, and Shirahata S, Cytotechnology, 31, 133-141 (1999).
7. Tamura T, Tomimatsu K, Katakura Y, Yamashita M, Matsumoto SE, Aiba Y, Jung YS, Abe Y, Fujiki T, Teruya K, and Shirahata S, Biosci. Biotechnol. Biochem., 71, 2871-2875 (2007).
8. Verthelyi D, Ishii KJ, Gursel M, Takeshita F, and Klinman DM, J. Immunol, 166, 2372-2377 (2001).
9. Yamashita M, Katakura Y, Shim SY, Matsumoto SE, Tamura T, Morihara K, Aiba Y, Teruya K, Tsuchiya T, and Shirahata S, Cytotechnology, 40, 161-165 (2002).
10. Xu Q, Katakura Y, Yamashita M, Fang S, Tamura T, Matsumoto SE, Aiba Y, Teruya K, Osada K, Nishikawa R, and Shirahata S, Biosci. Biotechnol. Biochem., 68, 2279-2284 (2004).
11. Matsumoto SE, Yamashita M, Katakura Y, Aiba Y, Tomimatsu K, Kabayama S, Teruya K, and Shirahata S, J. Immunol. Methods, 332, 2-9 (2008).
12. Barbanti E, Corti A, Ghislieri M, Trizio D, and Marcucci F, Pharmacol. Res., 26 (Suppl 2), 144-145 (1992).
13. Socher SH, Riemen MW, Martinez D, Friedman A, Tai J, Quintero JC, Garsky V, and Oliff A, Proc. Natl. Acad. Sci. USA, 84, 8829-8833 (1987).
14. McConnell SJ, Dinh T, Le MH, and Spinella DG, Biotechni-ques, 26, 208-210, 214 (1999).