Anti-peptide antibody production elicited by in vitro immunization of human peripheral blood mononuclear cells

Bioscience, Biotechnology and Biochemistry

Volumn 71, Issue 12, 2007, Pages 2871-2875

  Tamura, Takashi ^a   Tomimatsu, Kosuke ^a   Katakura, Yoshinori ^a   Yamashita, Makiko ^a   Matsumoto, Shin Ei ^a   Aiba, Yoshihiro ^a   Jung, Yeon Suk ^a   Abe, Yoshiichi ^a   Fujiki, Tsukasa ^a   Teruya, Kiichiro ^a   Shirahata, Sanetaka ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Antibody production; In vitro immunization; Peptide antigen

Indexed keywords

ANTIBODY PRODUCTION; IN VITRO IMMUNIZATION; PEPTIDE ANTIGEN;

BLOOD; CELLS; DISEASES; IMMUNIZATION; PEPTIDES;

MONOCLONAL ANTIBODIES;

ALLERGEN; CHOLERA TOXIN; DIPEPTIDE; INTERLEUKIN 2; LEUCYL LEUCINE METHYL ESTER; LEUCYL-LEUCINE-METHYL ESTER; MONOCLONAL ANTIBODY; PEPTIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIBODY PRODUCTION; ARTICLE; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; HUMAN; IMMUNIZATION; IMMUNOLOGY; MONONUCLEAR CELL; RICE;

ALLERGENS; ANTIBODIES, MONOCLONAL; ANTIBODY FORMATION; CELLS, CULTURED; CHOLERA TOXIN; DIPEPTIDES; HUMANS; IMMUNIZATION; INTERLEUKIN-2; LEUKOCYTES, MONONUCLEAR; ORYZA SATIVA; PEPTIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 37649019860     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.60460     Document Type: Article

References (17)

1. Hwang, W. Y., and Foote, J., Immunogenicity of engineered antibodies. Methods, 36, 3-10 (2005).
2. Kricka, L. J., Human anti-animal antibody interferences in immunological assays. Clin. Chem., 45, 942-956 (1999).
3. Thiele, D. L., and Lipsky, P. E., The immunosuppressive activity of L-leucyl-L-leucine methyl ester: selective ablation of cytotoxic lymphocytes and monocytes. J. Immunol., 136, 1038-1048 (1986).
4. James, K., and Bell, G. T., Human monoclonal antibody production. Current status and future prospects. J. Immunol. Methods, 100, 5-40 (1987).
5. Bahr, G. M., Modabber, F. Z., Morin, A., Terrier, M., Eyquem, A., and Chedid, L., Regulation by muramyl dipeptide (MDP) of the lymphoproliferative responses and polyclonal activation of human peripheral blood mononuclear cells. Clin. Exp. Immunol., 57, 178-186 (1984).
6. Ichikawa, A., Katakura, Y., Teruya, K., Hashizume, S., and Shirahata, S., In vitro immunization of human peripheral blood lymphocytes: establishment of B cell lines secreting IgM specific for cholera toxin B subunit from lymphocyte stimulated with IL-2 and IL-4. Cytotechnol., 31, 131-139 (1999).
7. Matsuda, T., Sugiyama, M., Nakamura, R., and Torii, S., Purification and properties of an allergenic protein in rice grains. Agric. Biol. Chem., 52, 1465-1470 (1988).
8. Xu, Q., Katakura, Y., Yamashita, M., Fang, S., Tamura, T., Matsumoto, S. E., Aiba, Y., Teruya, K., Osada, K., Nishikawa, R., and Shirahata, S., IL-10 augments antibody production in in vitro immunized lymphocytes by inducing a Th2-type response and B cell maturation. Biosci. Biotechnol. Biochem., 68, 2279-2284 (2004).
9. Yamashita, M., Katakura, Y., Shim, S. Y., Matsumoto, S., Tamura, T., Morihara, K., Aiba, Y., Teruya, K., Tsuchiya, T., and Shirahata, S., Different individual immune responses elicited by in vitro immunization. Cytotechnol., 40, 161-165 (2002).
10. Matsumoto, S., Yamashita, M., Katakura, Y., Nurakami, E., Aiba, Y., Ichikawa, A., Teruya, K., and Shirahata, S., In vitro immunization can elicit the expansion of diverse repertoire of B cells from peripheral blood mononuclear cells. Cytotechnol., 52, 227-233 (2006).
11. Shibasaki, M., Suzuki, S., Nemoto, H., and Kuroume, T., Allergenicity and lymphocyte-stimulating property of rice protein. J. Allergy Clin. Immunol., 64, 259-265 (1979).
12. Jacob, C. O., Sela, M., and Arnon, R., Antibodies against synthetic peptides of the B subunit of cholera toxin: crossreaction and neutralization of the toxin. Proc. Natl. Acad. Sci. USA, 80, 7611-7615 (1983).
13. Bazzoni, F., and Beutler, B., The tumor necrosis factor ligand and receptor families. N. Engl. J. Med., 334, 1717-1725 (1996).
14. Eigler, A., Sinha, B., Hartmann, G., and Endres, S., Taming TNF: strategies to restrain this proinflammatory cytokine. Immunol. Today, 18, 487-492 (1997).
15. Socher, S. H., Riemen, M. W., Martinez, D., Friedman, A., Tai, J., Quintero, J. C., Garsky, V., and Oliff, A., Antibodies against amino acids 1-15 of tumor necrosis factor block its binding to cell-surface receptor. Proc. Natl. Acad. Sci. USA, 84, 8829-8833 (1987).
16. Zhang, X. M., Weber, I., and Chen, M. J., Site-directed mutational analysis of human tumor necrosis factor-alpha receptor binding site and structure-functional relationship. J. Biol. Chem., 267, 24069-24075 (1992).
17. Shim, S., Katakura, Y., Ichikawa, A., Teruya, K., Matsuda, T., and Shirahata, S., Epitope analysis of human monoclonal antibody specific for rice allergenic protein generated by in vitro immunization. Cytotechnol., 36, 109-115 (2001).