Exercise rehabilitation on home-dwelling patients with Alzheimer's disease - a randomized, controlled trial. Study protocol

Trials

Volumn 11, Issue , 2010, Pages

  Pitkala, Kaisu H ^a   Raivio, Minna M ^a,b   Laakkonen, Marja Liisa ^a,c   Tilvis, Reijo S ^a   Kautiainen, Hannu ^d,e,h   Strandberg, Timo E ^f,g  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b SOCIAL INSURANCE INSTITUTION   (Finland)

^c Laakso Hospital   (Finland)

^d ORTON ORTHOPAEDIC HOSPITAL   (Finland)

^e Central Finland Central Hospital   (Finland)

^f UNIVERSITY OF OULU   (Finland)

^g Unit of General Practice   (Finland)

^h Unit of General Practice ^*  (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ARTICLE; CLINICAL TRIAL; COGNITION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; EXERCISE; FOLLOW UP; HEALTH CARE COST; HOME REHABILITATION; HUMAN; INSTITUTIONAL CARE; MAJOR CLINICAL STUDY; MENTAL DISEASE; MULTICENTER STUDY; NUTRITION SERVICE; OUTCOME ASSESSMENT; PHYSICAL ACTIVITY; PHYSICAL MOBILITY; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; REHABILITATION CENTER; SOCIAL WORK; AGED; BODY EQUILIBRIUM; CAREGIVER; CLINICAL PROTOCOL; COST BENEFIT ANALYSIS; COST OF ILLNESS; DAY CARE; DISABILITY; ECONOMICS; FINLAND; FRAIL ELDERLY; INDEPENDENT LIVING; KINESIOTHERAPY; METHODOLOGY; NEUROPSYCHOLOGICAL TEST; PATHOPHYSIOLOGY; PSYCHOLOGICAL ASPECT; TIME; TREATMENT OUTCOME; WALKING; WALKING DIFFICULTY;

AGED; ALZHEIMER DISEASE; CAREGIVERS; CLINICAL PROTOCOLS; COGNITION; COST OF ILLNESS; COST-BENEFIT ANALYSIS; DAY CARE; DEPRESSION; DISABILITY EVALUATION; EXERCISE THERAPY; FINLAND; FRAIL ELDERLY; HEALTH CARE COSTS; HUMANS; INDEPENDENT LIVING; MOBILITY LIMITATION; NEUROPSYCHOLOGICAL TESTS; POSTURAL BALANCE; QUALITY OF LIFE; RESEARCH DESIGN; TIME FACTORS; TREATMENT OUTCOME; WALKING;

EID: 77957324826     PISSN: 17456215     EISSN: 17456215     Source Type: Journal    
DOI: 10.1186/1745-6215-11-92     Document Type: Article

References (32)

1. Alzheimer's Association 2010 Alzheimer's disease facts and figures. Alzheimers Dement 2010, 6:158-94. 10.1016/j.jalz.2010.01.009, 20298981, Alzheimer's Association.
2. Knoptman D, Richie K, Polge C, Alafuzoff I, Soininen H. Alzheimer's disease. Evidence-based dementia practice 2002, 228-59. Oxford: Blackwell Publishing, Qizilbash N, Schneider LS, Chui H, Tariot P, Brodaty H, Kaye J, Erkinjuntti T.
3. Cotter VT. The burden of dementia. Am J Manag Care 2007, 13(Suppl):193-197.
4. Gillette Guyonnet S, Abellan Van Kan G, Alix E, Andrieu S, Belmin J, Berrut G, Bonnefoy M, Brocker P, Constans T, Ferry M, Ghisolfi-Marque A, Girard L, Gonthier R, Guerin O, Hervy MP, Jouanny P, Laurain MC, Lechowski L, Nourhashemi F, Raynaud-Simon A, Ritz P, Roche J, Rolland Y, Salva T, Vellas B, . International Academy on Nutrition and Aging Expert Group, IANA (International Academy on Nutrition and Aging) Expert Group Weight loss and Alzheimer's disease. J Nutr Health Aging 2007, 11:38-48. International Academy on Nutrition and Aging Expert Group, IANA (International Academy on Nutrition and Aging) Expert Group.
5. Kramer AF, Erickson KI, Colcombe SJ. Exercise, cognition, and aging brain. J Appl Physiol 2006, 101:1237-1242. 10.1152/japplphysiol.00500.2006, 16778001.
6. Lautenschlager NT, Cox KL, Flicker L, Foster JK, van Bockxmeer FM, Xiao J, Greenop KR, Almeida OP. Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial. JAMA 2008, 300:1027-1037. 10.1001/jama.300.9.1027, 18768414.
7. Heyn P, Abreu BC, Ottenbacher KJ. The effects of exercise training on elderly persons with cognitive impairment and dementia: a meta-analysis. Arch Phys Med Rehabil 2004, 85:1694-1704. 10.1016/j.apmr.2004.03.019, 15468033.
8. Teri L, Gibbons LE, McCurry SM, Logsdon RG, Buchner DM, Barlow WE, Kukull WA, LaCroix AZ, McCormick W, Larson EB. Exercise plus behavioral management in patients with Alzheimer disease: a randomized controlled trial. JAMA 2003, 290:2015-2022. 10.1001/jama.290.15.2015, 14559955.
9. Heyn PC, Johnson KE, Kramer AF. Endurance and strength training outcomes on cognitively impaired and cognitively intact older adults: a meta-analysis. J Nutr Health Aging 2008, 12:401-409. 10.1007/BF02982674, 2853480, 18548179.
10. Rolland Y, Pillard F, Klapouszczak A, Reynish E, Thomas D, Andrieu S, Riviere D, Vellas B. Exercise program for nursing home residents with Alzheimer's disease: a 1-year randomized, controlled trial. J Am Geriatr Soc 2007, 55:158-165. 10.1111/j.1532-5415.2007.01035.x, 17302650.
11. Pomeroy VM, Warren CM, Honeycombe C, Briggs RS, Wilkinson DG, Pickering RM, Steiner A. Mobility and dementia: is physiotherapy treatment during respite care effective?. Int J Geriatr Psychiatry 1999, 14:389-397. 10.1002/(SICI)1099-1166(199905)14:5<389::AID-GPS933>3.0.CO;2-8, 10389044.
12. Netz Y, Axelrad S, Argov E. Group physical activity for demented older adults feasibility and effectiveness. Clin Rehabil 2007, 21:977-986. 10.1177/0269215507078318, 17984150.
13. Kwak YS, Um SY, Son TG, Kim DJ. Effect of regular exercise on senile dementia patients. Int J Sports Med 2008, 29:471-474. 10.1055/s-2007-964853, 18050054.
14. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987, 40:373-383. 10.1016/0021-9681(87)90171-8, 3558716.
15. Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL. A new clinical scale for the staging of dementia. Br J Psychiatry 1982, 140:566-572. 10.1192/bjp.140.6.566, 7104545.
16. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975, 12:189-198. 10.1016/0022-3956(75)90026-6, 1202204.
17. Morris JC, Heyman A, Mohs RC, Hughes JP, van Belle G, Fillenbaum G, Mellits ED, Clark C. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease. Neurology 1989, 39:1159-1165.
18. Welsh K, Butters N, Hughes J, Mohs R, Heyman A. Detection of abnormal memory decline in mild cases of Alzheimer's disease using CERAD neuropsychological measures. Arch Neurol 1991, 48:278-281.
19. Sunderland T, Hill JL, Mellow AM, Lawlor BA, Gundersheimer J, Newhouse PA, Grafman JH. Clock drawing in Alzheimer's disease. A novel measure of dementia severity. J Am Geriatr Soc 1989, 37:725-729.
20. Guigoz Y, Lauque S, Vellas BJ. Identifying the elderly at risk for malnutrition the Mini Nutritional Assessment. Clin Geriatr Med 2002, 18:737-757. 10.1016/S0749-0690(02)00059-9, 12608501.
21. Cummings JL, Mega M, Gray K, Rosenberg-Thompson S, Carusi DA, Gornbein J. The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology 1994, 44:2308-2014.
22. Cummings JL. The Neuropsychiatric Inventory: assessing psychopathology in dementia patients. Neurology 1997, 48(Suppl):10-16.
23. Alexopoulos GS, Abrams RC, Young RC, Shamoian CA. Cornell scale for depression in dementia. Biol Psychiatry 1988, 23:271-284. 10.1016/0006-3223(88)90038-8, 3337862.
24. Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, Scherr PA, Wallace RB. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 1994, 49:M85-94.
25. Pollak N, Rheault W, Stoecker JL. Reliability and validity of the FIM for persons aged 80 years and above from a multilevel continuing care retirement community. Arch Phys Med Rehabil 1996, 77:1056-1061. 10.1016/S0003-9993(96)90068-4, 8857886.
26. Rantanen T, Volpato S, Ferrucci L, Heikkinen E, Fried LP, Guralnik JM. Handgrip strength and cause-specific and toltal mortality in older disabled women: exploring mechanism. J Am Geriatr Soc 2003, 51:636-641. 10.1034/j.1600-0579.2003.00207.x, 12752838.
27. Zarit SH, Reever KE, Bach-Peterson J. Relatives of the impaired elderly: correlates of feelings of burden. Gerontologist 1980, 20:649-655.
28. Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, Leirer VO. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 1982, 17:37-49. 10.1016/0022-3956(82)90033-4, 7183759.
29. Aalto A, Aro A, Teperi J. RAND-36 as a measure of health-related quality of life. reliability, construct validity and reference values in the finnish genera population. Report No. 101. 1999, Helsinki: Stakes.
30. Parker SG, Bechinger-English D, Jagger C, Spiers N, Lindesay J. Factors affecting completion of the SF-36 in older people. Age Ageing 2006, 35:376-381. 10.1093/ageing/afl003, 16638761.
31. Tang BM, Eslick GD, Nowson C, Smith C, Bensoussan A. Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis. Lancet 2007, 370:657-666. 10.1016/S0140-6736(07)61342-7, 17720017.
32. Raivio M, Eloniemi-Sulkava U, Laakkonen ML, Saarenheimo M, Pietilä M, Tilvis R, Pitkälä K. How do officially organized services meet the needs of elderly caregivers and their spouses with Alzheimer's disease?. Am J Alzheimers Dis Other Demen 2007, 22:360-368. 10.1177/1533317507305178, 17959871.