Isolation and structure elucidation of tumescenamides A and B, two peptides produced by Streptomyces tumescens YM23-260

Journal of Antibiotics

Volumn 63, Issue 9, 2010, Pages 549-552

  Motohashi, Keiichiro ^a   Toda, Takashi ^a   Sue, Masayuki ^a   Furihata, Kazuo ^b   Shizuri, Yoshikazu ^c   Matsuo, Yoshihide ^d,g   Kasai, Hiroaki ^c   Shin Ya, Kazuo ^e   Takagi, Motoki ^e   Izumikawa, Miho ^e   Horikawa, Yukio ^f   Seto, Haruo ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c KITASATO UNIVERSITY   (Japan)

^d MARINE BIOTECHNOLOGY INSTITUTE   (Japan)

^e Koto ku   (Japan)

^f GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g SUNTORY LTD   (Japan)

Author keywords

insulin degrading enzyme; pentapeptide; Streptomyces tumescens; tumescenamide

Indexed keywords

BACTERIAL PROTEIN; INSULINASE; LEUCINE; PLASMID VECTOR; THREONINE; TUMESCENAMIDE A; TUMESCENAMIDE B; TYROSINE; UNCLASSIFIED DRUG; VALINE; AMINO ACID; DEPSIPEPTIDE; LUCIFERASE;

ARTICLE; BIOLOGICAL ACTIVITY; CELL CULTURE; ENZYME ACTIVITY; FERMENTATION; GENE EXPRESSION; ISOLATION AND PURIFICATION; NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY; STREPTOMYCES; STREPTOMYCES TUMESCENS; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROMOTER REGION; REPORTER GENE; SECRETION (PROCESS); TRANSCRIPTION INITIATION;

BACTERIA (MICROORGANISMS); STREPTOMYCES TUMESCENS;

AMINO ACIDS; DEPSIPEPTIDES; GENES, REPORTER; INSULYSIN; LUCIFERASES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PROMOTER REGIONS, GENETIC; STREPTOMYCES; TRANSCRIPTIONAL ACTIVATION;

EID: 77957315231     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2010.73     Document Type: Article

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