Kinetic basis for global loss of fidelity arising from mismatches in the P-site codon:Anticodon helix

RNA

Volumn 16, Issue 10, 2010, Pages 1980-1989

  Zaher, Hani S ^a   Green, Rachel ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Perturbed P site; Protein synthesis fidelity; Quality control; Ribosome; tRNA selection

Indexed keywords

GUANOSINE TRIPHOSPHATASE; MESSENGER RNA; TRANSFER RNA; ANTICODON; BACTERIAL RNA; CODON; ELONGATION FACTOR TU; FUNGAL RNA; TRANSLATION TERMINATION FACTOR;

ANTICODON; ARTICLE; CODON; ENZYME ACTIVATION; ENZYME SUBSTRATE; PLEIOTROPY; PRIORITY JOURNAL; RNA ANALYSIS; BASE MISPAIRING; BINDING SITE; BIOLOGICAL MODEL; CHEMISTRY; CONFORMATION; ESCHERICHIA COLI; GENETICS; KINETICS; METABOLISM; NUCLEOTIDE SEQUENCE; RIBOSOME; RNA TRANSLATION;

ANTICODON; BASE PAIR MISMATCH; BASE SEQUENCE; BINDING SITES; CODON; ESCHERICHIA COLI; GTP PHOSPHOHYDROLASES; KINETICS; MODELS, BIOLOGICAL; NUCLEIC ACID CONFORMATION; PEPTIDE CHAIN ELONGATION, TRANSLATIONAL; PEPTIDE ELONGATION FACTOR TU; PEPTIDE TERMINATION FACTORS; RIBOSOMES; RNA, BACTERIAL; RNA, FUNGAL;

EID: 77957307036     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.2241810     Document Type: Article

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