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Volumn 19, Issue 4, 2010, Pages 419-428

Anticancer properties of Scutellaria baicalensis root in aspect of innate immunity regulation

Author keywords

Anticancer properties; Effect on innate immunity; Inhibition of cell cycle; Reduction of inflammation; Scutellaria baicalensis flavones; Stimulation of apoptosis

Indexed keywords

2',3',5,7 TETRAHYDROXYFLAVONE; 2',5,7 TRIHYDROXYFLAVONE; ANTIVIRUS AGENT; BAICALEIN; BAICALIN; CYCLINE; CYCLOOXYGENASE 2 INHIBITOR; CYTOKINE; ETOPOSIDE; FLAVONOID; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; OROXYLIN A; PC SPES; REACTIVE OXYGEN METABOLITE; SCUTELLARIA BAICALENSIS EXTRACT; UNCLASSIFIED DRUG; WOGONIN; WOGONOSIDE;

EID: 77957302789     PISSN: 1230025X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (13)

References (49)
  • 3
    • 0034025809 scopus 로고    scopus 로고
    • Antitumor effects of Scutellariae radix and its components Baicalein, Baicalin and Wogonin on bladder cancer cell lines
    • Ikemoto S, Sugimura K, Yoshida N, Yasumamoto K at al.: Antitumor effects of Scutellariae radix and its components Baicalein, Baicalin and Wogonin on bladder cancer cell lines. Urology 2000, 55, 951-955.
    • (2000) Urology , vol.55 , pp. 951-955
    • Ikemoto, S.1    Sugimura, K.2    Yoshida, N.3    Yasumamoto, K.4
  • 4
    • 4344625904 scopus 로고    scopus 로고
    • Effect of baikal skullcap extract administered alone or in combination with cyclophosphamide on natural cytotoxicity system in mice with Lewis lung carcinoma
    • Kaplya OA, Sherstoboev EY, Zueva EP, Razina TG, Amosova EN, Krylova SG: Effect of baikal skullcap extract administered alone or in combination with cyclophosphamide on natural cytotoxicity system in mice with Lewis lung carcinoma Bull Exp Biol Med 2004, 137, 471-474.
    • (2004) Bull Exp Biol Med , vol.137 , pp. 471-474
    • Kaplya, O.A.1    Sherstoboev, E.Y.2    Zueva, E.P.3    Razina, T.G.4    Amosova, E.N.5    Krylova, S.G.6
  • 5
    • 41649090478 scopus 로고    scopus 로고
    • Study on molecular mechanism of inhibitory effect of baicalin on proliferation of insulinoma cell line in rats
    • Sun JP, Jia YJ, Song J: Study on molecular mechanism of inhibitory effect of baicalin on proliferation of insulinoma cell line in rats. Zhongguo Zhong Xi Yi Jie He Za Zhi 2006, 26, 337-340.
    • (2006) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.26 , pp. 337-340
    • Sun, J.P.1    Jia, Y.J.2    Song, J.3
  • 6
    • 58749114381 scopus 로고    scopus 로고
    • New therapeutic aspects of flavones; The anticancer properties of Scutellaria and its main active constituens Wogonin, Baicalein and Baicalin
    • Li-Weber M: New therapeutic aspects of flavones; The anticancer properties of Scutellaria and its main active constituens Wogonin, Baicalein and Baicalin. Cancer Treat Rev 2009, 35, 57-68.
    • (2009) Cancer Treat Rev , vol.35 , pp. 57-68
    • Li-Weber, M.1
  • 7
    • 0033794615 scopus 로고    scopus 로고
    • Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin
    • Graduate Institute of Natural Products, Kaohsiung Medical University, Taiwan
    • Shieh DE, Liu LT, Lin CC: Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin. Graduate Institute of Natural Products, Kaohsiung Medical University, Taiwan. Anticancer Res 2000, 20(5A), 2861-2865.
    • (2000) Anticancer Res , vol.20 , Issue.5 A , pp. 2861-2865
    • Shieh, D.E.1    Liu, L.T.2    Lin, C.C.3
  • 8
    • 4444379675 scopus 로고    scopus 로고
    • In vitro antileukemic, antioxidant and prooxidant activities of Antoksyd S(C/E/XXI): A comparison with baicalin and baicalein
    • Ciesielska E, Wolszczak M, Gulanowski B, Szulawska A, Metodieva D: In vitro antileukemic, antioxidant and prooxidant activities of Antoksyd S(C/E/XXI): a comparison with baicalin and baicalein. In Vivo 2004, 18, 497-503.
    • (2004) In Vivo , vol.18 , pp. 497-503
    • Ciesielska, E.1    Wolszczak, M.2    Gulanowski, B.3    Szulawska, A.4    Metodieva, D.5
  • 9
    • 20144387818 scopus 로고    scopus 로고
    • Baicalein, a component of Scutellaria radix from Huang-Lian-Jie-Du-Tang (HLJDT), leads to suppression of proliferation and induction of apoptosis in human myeloma cells
    • Ma Z, Otsuyama K, Liu S, Abroun S, Ishikawa H, Tsuyama N, Obata M, Li FJ, Zheng X, Maki Y, Miyamoto K, Kawano MM: Baicalein, a component of Scutellaria radix from Huang-Lian-Jie-Du-Tang (HLJDT), leads to suppression of proliferation and induction of apoptosis in human myeloma cells. Blood 2005, 105, 3312-3318.
    • (2005) Blood , vol.105 , pp. 3312-3318
    • Ma, Z.1    Otsuyama, K.2    Liu, S.3    Abroun, S.4    Ishikawa, H.5    Tsuyama, N.6    Obata, M.7    Li, F.J.8    Zheng, X.9    Maki, Y.10    Miyamoto, K.11    Kawano, M.M.12
  • 10
    • 18844437520 scopus 로고    scopus 로고
    • Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma
    • DOI 10.1158/1078-0432.CCR-04-1974
    • Bonham M, Posakony J, Coleman I, Montgomery B, Simon J, Nelson PS: Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma. Clin Cancer Res 2005 May 15, 11(10), 3905-3914. (Pubitemid 40685612)
    • (2005) Clinical Cancer Research , vol.11 , Issue.10 , pp. 3905-3914
    • Bonham, M.1    Posakony, J.2    Coleman, I.3    Montgomery, B.4    Simon, J.5    Nelson, P.S.6
  • 11
    • 33846684768 scopus 로고    scopus 로고
    • Scutellaria baicalensis, a herbal medicine: Anti-proliferative and apoptotic activity against acute lymphocytic leukemia, lymphoma and myeloma cell lines
    • Kumagai T, Müller CI, Desmond JC, Imai Y, Heber D, Koeffler HP: Scutellaria baicalensis, a herbal medicine: anti-proliferative and apoptotic activity against acute lymphocytic leukemia, lymphoma and myeloma cell lines. Leuk Res 2007, 31, 523-530.
    • (2007) Leuk Res , vol.31 , pp. 523-530
    • Kumagai, T.1    Müller, C.I.2    Desmond, J.C.3    Imai, Y.4    Heber, D.5    Koeffler, H.P.6
  • 13
    • 0141852335 scopus 로고    scopus 로고
    • Effects of wogonin, a plant flavone from Scutellaria radix, on skin inflammation: In vivo regulation of inflammation-associated gene expression
    • DOI 10.1016/S0006-2952(03)00463-5
    • Chi YS, Lim H, Park H, Kim HP: Effects of wogonin, a plant flavone from Scutellaria radix, on skin inflammation: in vivo regulation of inflammation-associated gene expression. Biochem Pharmacol 2003 Oct 1, 66(7), 1271-1278. (Pubitemid 37130302)
    • (2003) Biochemical Pharmacology , vol.66 , Issue.7 , pp. 1271-1278
    • Chi, Y.S.1    Lim, H.2    Park, H.3    Kim, H.P.4
  • 14
    • 33750428201 scopus 로고    scopus 로고
    • Antioxidative and Anti-Inflammatory Activities of Polyhydroxyflavonoids of Scutellaria baicalensis Georgi
    • Oct, Epub 2006 Oct 7
    • Huang WH, Lee AR, Yang, CH: Antioxidative and Anti-Inflammatory Activities of Polyhydroxyflavonoids of Scutellaria baicalensis Georgi. Biosci Biotechnol Biochem 2006 Oct, 70(10), 2371-2380. Epub 2006 Oct 7.
    • (2006) Biosci Biotechnol Biochem , vol.70 , Issue.10 , pp. 2371-2380
    • Huang, W.H.1    Lee, A.R.2    Yang, C.H.3
  • 15
    • 10944247380 scopus 로고    scopus 로고
    • Inhibition of contact dermatitis in animal models and suppression of proinflammatory gene expresson by topically applied flavonoid, Wogonin
    • Lim H, Park H, Kim HP: Inhibition of contact dermatitis in animal models and suppression of proinflammatory gene expresson by topically applied flavonoid, Wogonin. Arch Pharm Res 2004, 27, 442-448.
    • (2004) Arch Pharm Res , vol.27 , pp. 442-448
    • Lim, H.1    Park, H.2    Kim, H.P.3
  • 16
    • 0036215314 scopus 로고    scopus 로고
    • Evaluation of the anti-inflammatory effect of Baicalein on dextran sulfate sodium-induced colitis in mice
    • Hong T, Jin GB, Cho S, Cyong JC: Evaluation of the anti-inflammatory effect of Baicalein on dextran sulfate sodium-induced colitis in mice. Planta Med 2002, 68, 268-271.
    • (2002) Planta Med , vol.68 , pp. 268-271
    • Hong, T.1    Jin, G.B.2    Cho, S.3    Cyong, J.C.4
  • 18
    • 0141852335 scopus 로고    scopus 로고
    • Effects of wogonin, a plant flavone from Scutellaria radix, on skin inflammation: In vivo regulation of inflammation-associated gene expression
    • DOI 10.1016/S0006-2952(03)00463-5
    • Chi YS, Lim H, Park H, Kim HP: Effect of wogonin, a plant flavone from Scutellaria radix on skin inflammation: in vivo regulation of inflammation-associated gene expression. Biochem Pharmacol 2003, 66, 1271-1278. (Pubitemid 37130302)
    • (2003) Biochemical Pharmacology , vol.66 , Issue.7 , pp. 1271-1278
    • Chi, Y.S.1    Lim, H.2    Park, H.3    Kim, H.P.4
  • 19
    • 0035903037 scopus 로고    scopus 로고
    • The plant flavonoid Wogonin suppresses death of activated C6 glial cells by inhibiting nitric oxide production
    • Kim H, Kim YS, Kim SY, Suk K: The plant flavonoid Wogonin suppresses death of activated C6 glial cells by inhibiting nitric oxide production. Neurosci Lett 2001, 309, 67-71.
    • (2001) Neurosci Lett , vol.309 , pp. 67-71
    • Kim, H.1    Kim, Y.S.2    Kim, S.Y.3    Suk, K.4
  • 20
    • 0035371508 scopus 로고    scopus 로고
    • Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide
    • Jun 1
    • Chen YC, Shen SC, Chen LG, Lee TJ, Yang LL: Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide. Biochem Pharmacol 2001 Jun 1, 61(11), 1417-1427.
    • (2001) Biochem Pharmacol , vol.61 , Issue.11 , pp. 1417-1427
    • Chen, Y.C.1    Shen, S.C.2    Chen, L.G.3    Lee, T.J.4    Yang, L.L.5
  • 21
    • 33745559710 scopus 로고    scopus 로고
    • The role of nitric oxide in tumour progression
    • DOI 10.1038/nrc1910, PII N1910
    • Fukumura D, Kashiwagi S, Jain RK: The role of nitric oxide in tumor progression. Nat Rev Cancer 2006, 6, 521-534. (Pubitemid 43980541)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.7 , pp. 521-534
    • Fukumura, D.1    Kashiwagi, S.2    Jain, R.K.3
  • 22
    • 1042298763 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase expression by Baicalein in endotoxin/cytokine-stimulated microglia
    • Chen CJ, RaungSI, Liao SL, Chen SY: Inhibition of inducible nitric oxide synthase expression by Baicalein in endotoxin/cytokine-stimulated microglia. Biochem Pharmacol 2004, 67, 957-965.
    • (2004) Biochem Pharmacol , vol.67 , pp. 957-965
    • Chen, C.J.1    Raung, S.I.2    Liao, S.L.3    Chen, S.Y.4
  • 23
    • 10344232459 scopus 로고    scopus 로고
    • Suppression of cyclooxygenase-2 expression of skin fibroblasts by wogonin, a plant flavone from Scutellaria radix
    • Jan
    • Chi YS, Kim HP: Suppression of cyclooxygenase-2 expression of skin fibroblasts by wogonin, a plant flavone from Scutellaria radix. Prostaglandins Leukot Essent Fatty Acids 2005 Jan, 72(1), 59-66.
    • (2005) Prostaglandins Leukot Essent Fatty Acids , vol.72 , Issue.1 , pp. 59-66
    • Chi, Y.S.1    Kim, H.P.2
  • 24
    • 55949100195 scopus 로고    scopus 로고
    • Wogonin, a bioactive flavonoid in herbal tea, inhibits inflammatory cyclooxygenase-2 gene expression in human lung epithelial cancer cells
    • Chen LG, Hung LY, Tsai KW, Pan YS, Tsai YD, Li YZ, Liu YW: Wogonin, a bioactive flavonoid in herbal tea, inhibits inflammatory cyclooxygenase-2 gene expression in human lung epithelial cancer cells. Mol Nutr Food Res 2008, 52, 1349-1357.
    • (2008) Mol Nutr Food Res , vol.52 , pp. 1349-1357
    • Chen, L.G.1    Hung, L.Y.2    Tsai, K.W.3    Pan, Y.S.4    Tsai, Y.D.5    Li, Y.Z.6    Liu, Y.W.7
  • 25
    • 0041672474 scopus 로고    scopus 로고
    • Inhibition of Cancer Cell Proliferation and Prostaglandin E2 Synthesis by Scutellaria baicalensis
    • Jul 15
    • Zhang DY, Wu J, Ye F, Xue L, Jiang S, Yi J, Zhang W, Wei H, Sung M, Wang W, Li X: Inhibition of Cancer Cell Proliferation and Prostaglandin E2 Synthesis by Scutellaria baicalensis. Cancer Res 2003, Jul 15, 63(14), 4037-4043.
    • (2003) Cancer Res , vol.63 , Issue.14 , pp. 4037-4043
    • Zhang, D.Y.1    Wu, J.2    Ye, F.3    Xue, L.4    Jiang, S.5    Yi, J.6    Zhang, W.7    Wei, H.8    Sung, M.9    Wang, W.10    Li, X.11
  • 27
    • 48049092641 scopus 로고    scopus 로고
    • Come back to root - Therapeutic activities of Scutellaria baicalensis root in aspect of innate immunity regulation - part I
    • Błach-Olszewska Z, Lamer-Zarawska E: Come back to root - therapeutic activities of Scutellaria baicalensis root in aspect of innate immunity regulation - part I. Adv Clin Exp Med 2008, 17, 337-346.
    • (2008) Adv Clin Exp Med , vol.17 , pp. 337-346
    • Błach-Olszewska, Z.1    Lamer-Zarawska, E.2
  • 28
    • 0026595909 scopus 로고
    • Inhibition of human T-cell leukemia virus by the plant flavonoid Baicalin (7-glucuronid acid,5,66-dihydroflavone)
    • Baylor NW, Fu T, Yan YD, Ruscetti FW: Inhibition of human T-cell leukemia virus by the plant flavonoid Baicalin (7-glucuronid acid,5,66-dihydroflavone). J Infect Dis 1992, 165, 433-437.
    • (1992) J Infect Dis , vol.165 , pp. 433-437
    • Baylor, N.W.1    Fu, T.2    Yan, Y.D.3    Ruscetti, F.W.4
  • 31
    • 0034721789 scopus 로고    scopus 로고
    • A comparison of human immunodeficiency virus type-1 protease inhibition activities by the aqueous and methanol extracts of Chinese medicinal herbs
    • Lam TL, Lam ML, Au TK, Ip DT, Ng TB, Fong WP, Van DC: A comparison of human immunodeficiency virus type-1 protease inhibition activities by the aqueous and methanol extracts of Chinese medicinal herbs. Life Sci 2000, 67, 2889-2896.
    • (2000) Life Sci , vol.67 , pp. 2889-2896
    • Lam, T.L.1    Lam, M.L.2    Au, T.K.3    Ip, D.T.4    Ng, T.B.5    Fong, W.P.6    Van, D.C.7
  • 33
    • 0034518886 scopus 로고    scopus 로고
    • Anti-hepatitis B virus effect of Wogonin isolated from Scutellaria baicalensis
    • Huang RI, Chen CC, Huang HI, Chang CC, Chen CF, Chang C et al.: Anti-hepatitis B virus effect of Wogonin isolated from Scutellaria baicalensis. Planta Med 2000, 66, 694-698.
    • (2000) Planta Med , vol.66 , pp. 694-698
    • Huang, R.I.1    Chen, C.C.2    Huang, H.I.3    Chang, C.C.4    Chen, C.F.5    Chang, C.6
  • 34
    • 33847642568 scopus 로고    scopus 로고
    • Anti-hepatitis B virus activity of wogonin in vitro and in vivo
    • DOI 10.1016/j.antiviral.2007.01.002, PII S0166354207000046
    • Guo Q, Zhao I, You Q, Yang Y, Gu H, Song G et al.: Anti-hepatitis B virus activity of Wogonin in vitro and in vivo. Antiviral Res 2007, 74, 16-24. (Pubitemid 46366014)
    • (2007) Antiviral Research , vol.74 , Issue.1 , pp. 16-24
    • Guo, Q.1    Zhao, L.2    You, Q.3    Yang, Y.4    Gu, H.5    Song, G.6    Lu, N.7    Xin, J.8
  • 35
    • 0042069727 scopus 로고    scopus 로고
    • Screening 20 Chinese herbs often used for clearing heat and dissipating toxin with nude mice model of hepatitis C viral infection
    • Tang ZM, Peng M, Zhan CJ: Screening 20 Chinese herbs often used for clearing heat and dissipating toxin with nude mice model of hepatitis C viral infection. Zhongguo Zhong Xi Yi Jie He Za Zhi 2003, 23, 447-448.
    • (2003) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.23 , pp. 447-448
    • Tang, Z.M.1    Peng, M.2    Zhan, C.J.3
  • 36
    • 1242314799 scopus 로고    scopus 로고
    • Complementary and alternative therapies in treatment of chronic hepatitis C: A systemic review
    • Coon JT, Ernst E: Complementary and alternative therapies in treatment of chronic hepatitis C: a systemic review. J Hepatology 2004, 40, 491-500.
    • (2004) J Hepatology , vol.40 , pp. 491-500
    • Coon, J.T.1    Ernst, E.2
  • 37
    • 0026575607 scopus 로고
    • Studies on inhibitors of skin tumor promotion. XI. Inhibitory effect of flavonoids from Scutellaria baicalensis on Epstain-Barr virus activation and their anti-tumor promoting activities
    • Konoshima T, Kokumai M, Kozuka M, Inuma M et al.: Studies on inhibitors of skin tumor promotion. XI. Inhibitory effect of flavonoids from Scutellaria baicalensis on Epstain-Barr virus activation and their anti-tumor promoting activities. Chem Pharm Bull 1992, 40, 531-533.
    • (1992) Chem Pharm Bull , vol.40 , pp. 531-533
    • Konoshima, T.1    Kokumai, M.2    Kozuka, M.3    Inuma, M.4
  • 38
    • 34147126361 scopus 로고    scopus 로고
    • Deficiency of innate immunity of leukocytes is associated with the failure of the induction of remission and survival time in patients with acute leukemia
    • Błach-Olszewska Z, Zaczyńska E, Kielbinski M, Frydecka I: Deficiency of innate immunity of leukocytes is associated with the failure of the induction of remission and survival time in patients with acute leukemia. Pol J Environ Stud 2005, 14, Suppl II, 36-40.
    • (2005) Pol J Environ Stud , vol.14 , Issue.SUPPL. II , pp. 36-40
    • Błach-Olszewska, Z.1    Zaczyńska, E.2    Kielbinski, M.3    Frydecka, I.4
  • 39
    • 68849086119 scopus 로고    scopus 로고
    • Anticancer immunotherapy using adjuvants with direct cytotoxic effects
    • Zitvogel L, Kroemer G: Anticancer immunotherapy using adjuvants with direct cytotoxic effects. J Clin Invest 2009, 119, 2127-2130.
    • (2009) J Clin Invest , vol.119 , pp. 2127-2130
    • Zitvogel, L.1    Kroemer, G.2
  • 40
    • 0036511201 scopus 로고    scopus 로고
    • Mechanism of action of herbal supplement PC-SPES: Elucidation of effects of individual herbs of PC-SPES on proliferation and prostate specific gene expression in androgen-dependent LNCaP cells
    • Hsieh TC, Wu JM: Mechanism of action of herbal supplement PC-SPES: elucidation of effects of individual herbs of PC-SPES on proliferation and prostate specific gene expression in androgen-dependent LNCaP cells. Int J Oncol 2002, 20, 583-588.
    • (2002) Int J Oncol , vol.20 , pp. 583-588
    • Hsieh, T.C.1    Wu, J.M.2
  • 41
    • 33745684501 scopus 로고    scopus 로고
    • Analysis of the interactions of botanical extract combination against the viability of prostate cancer cell lines
    • Adams LS, Seeram NP, Hardy ML Carpenter C, Heber D: Analysis of the interactions of botanical extract combination against the viability of prostate cancer cell lines. Evid Based Complement Altern Med 2006, 3, 117-124.
    • (2006) Evid Based Complement Altern Med , vol.3 , pp. 117-124
    • Adams, L.S.1    Seeram, N.P.2    Hardy, M.L.3    Carpenter, C.4    Heber, D.5
  • 43
    • 34249906468 scopus 로고    scopus 로고
    • Molecular mechanism of anti-prostate cancer activity of Scutellaria Baicalensis extract
    • Ye F, Jiang S, Volshonok H, Wu J, Zhang DY: Molecular mechanisms of anti-prostate cancer activity of Scutellaria baicalensis extract. Nutr Cancer 2007, 57, 100-110. (Pubitemid 46871574)
    • (2007) Nutrition and Cancer , vol.57 , Issue.1 , pp. 100-110
    • Ye, F.1    Jiang, S.2    Volshonok, H.3    Wu, J.4    Zhang, D.Y.5
  • 44
    • 0035212167 scopus 로고    scopus 로고
    • Baicalin is a major component of PC-SPES which inhibits the proliferation of human cancer cells via apoptosis and cell cycle arrest
    • Ikezoe T, Chen SS, Heber D, Taguchi H, Koeffler HP: Baicalin is a major component of PC-SPES which inhibits the proliferation of human cancer cells via apoptosis and cell cycle arrest. Prostate 2001, 49, 285-292.
    • (2001) Prostate , vol.49 , pp. 285-292
    • Ikezoe, T.1    Chen, S.S.2    Heber, D.3    Taguchi, H.4    Koeffler, H.P.5
  • 45
    • 0031590969 scopus 로고    scopus 로고
    • Inhibition of proliferation of estrogen receptor-positive MCF-7 human breast cancer cells by flavo- noids in the presence and absence of excess
    • So FV et al.: Inhibition of proliferation of estrogen receptor-positive MCF-7 human breast cancer cells by flavo- noids in the presence and absence of excess. Cancer Lett 1997, 112, 127-133.
    • (1997) Cancer Lett , vol.112 , pp. 127-133
    • So, F.V.1
  • 46
    • 45949094793 scopus 로고    scopus 로고
    • The role of Ca(2+) in baicelein-induced apoptosis in human breast MDA-MB-231 cancer cells through mitochondria- and caspase-3-dependent pathway
    • Lee JH, Li YC, Ip SW, Chang NM, Tang NY, Yu CS, Chou ST, Lin SS, Lino CC, Yang JS, Chung JG: The role of Ca(2+) in baicelein-induced apoptosis in human breast MDA-MB-231 cancer cells through mitochondria- and caspase-3-dependent pathway. Anticancer Res 2008, 28(3A), 1701-1711.
    • (2008) Anticancer Res , vol.28 , Issue.3 A , pp. 1701-1711
    • Lee, J.H.1    Li, Y.C.2    Ip, S.W.3    Chang, N.M.4    Tang, N.Y.5    Yu, C.S.6    Chou, S.T.7    Lin, S.S.8    Lino, C.C.9    Yang, J.S.10    Chung, J.G.11
  • 47
    • 68349092520 scopus 로고    scopus 로고
    • Proliferation of estrogen-responsive mouse tumor cell line B-1F stimulated by Saiboku-to, but inhibited by Scutellaria baicalensis, a component of Saiboku-to
    • Murashima T, Yamasaki M, Nishizawa Y, Katayama H, Tanigaki Y, Saeki Y, Shojiro K, Nishizawa Y: Proliferation of estrogen-responsive mouse tumor cell line B-1F stimulated by Saiboku-to, but inhibited by Scutellaria baicalensis, a component of Saiboku-to. Oncol Rep 2009, 22, 257-264.
    • (2009) Oncol Rep , vol.22 , pp. 257-264
    • Murashima, T.1    Yamasaki, M.2    Nishizawa, Y.3    Katayama, H.4    Tanigaki, Y.5    Saeki, Y.6    Shojiro, K.7    Nishizawa, Y.8
  • 48
    • 70649104033 scopus 로고    scopus 로고
    • Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells
    • Huang ST, Wang CY, Yang RC, Chu CJ, Wu HT, Pang JH: Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells. Phytomedicine 2010, 17, 47-54.
    • (2010) Phytomedicine , vol.17 , pp. 47-54
    • Huang, S.T.1    Wang, C.Y.2    Yang, R.C.3    Chu, C.J.4    Wu, H.T.5    Pang, J.H.6
  • 49
    • 70649114483 scopus 로고    scopus 로고
    • Selective fraction of Scutellaria bacalensis and its chemoprevetive effects on MCF-7 human breast cancer cells
    • Wang CZ, Li XL, Wang QF et al.: Selective fraction of Scutellaria bacalensis and its chemoprevetive effects on MCF-7 human breast cancer cells. Phytomedicine 2010, 17, 63-68.
    • (2010) Phytomedicine , vol.17 , pp. 63-68
    • Wang, C.Z.1    Li, X.L.2    Wang, Q.F.3


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