Open channel block of the fast transient outward K+ current by primaquine and chloroquine in rat left ventricular cardiomyocytes

European Journal of Pharmacology

Volumn 647, Issue 1-3, 2010, Pages 13-20

  Wagner, Michael ^a   Riepe, Konstantin Georg ^a   Eberhardt, Esther ^a   Volk, Tilmann ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Cardiomyocyte; Chloroquine; KChIP2; Kv4.2; Patch clamp; Primaquine; Transient outward K+ current; Two electrode voltage clamp; Xenopus laevis oocyte

Indexed keywords

CHLOROQUINE; PRIMAQUINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG ACTIVITY; DRUG STRUCTURE; EQUILIBRIUM CONSTANT; FEMALE; HEART LEFT VENTRICLE; HEART MUSCLE CELL; IC 50; KINETICS; NONHUMAN; OOCYTE; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT;

ACTION POTENTIALS; ANIMALS; ANTIMALARIALS; CHLOROQUINE; FEMALE; HEART; HEART VENTRICLES; ION CHANNEL GATING; MEMBRANE POTENTIALS; MYOCARDIUM; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; PRIMAQUINE; RATS; RATS, WISTAR; XENOPUS LAEVIS;

EID: 77957297299     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.08.007     Document Type: Article

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