PPARγ in placental angiogenesis

Endocrinology

Volumn 151, Issue 10, 2010, Pages 4969-4981

  Nadra, Karim ^a   Quignodon, Laure ^a   Sardella, Chiara ^a   Joye, Elisabeth ^a,b   Mucciolo, Antonio ^a   Chrast, Roman ^a   Desvergne, Béatrice ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROLIFERIN; PROLIFERIN RELATED PROTEIN; ROSIGLITAZONE; UNCLASSIFIED DRUG; VASCULOTROPIN; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT; GLYCOPROTEIN; PLF PROTEIN, MOUSE; SIGNAL PEPTIDE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CORRELATION ANALYSIS; DRUG ACTIVITY; ECTODERM; EMBRYO; EMBRYO DEATH; FEMALE; FETUS GROWTH; GENE DELETION; GENE EXPRESSION; MALE; METASTASIS; MICROVASCULATURE; MOUSE; NONHUMAN; PLACENTA; PLACENTA DEVELOPMENT; PRIORITY JOURNAL; VASCULARIZATION; ANIMAL; ANTIBODY SPECIFICITY; C57BL MOUSE; DRUG EFFECT; DRUG POTENTIATION; GENE EXPRESSION REGULATION; GENETICS; GERM LAYER; GESTATIONAL AGE; METABOLISM; PHYSIOLOGY; PREGNANCY; TRANSGENIC MOUSE;

ANIMALS; EMBRYO LOSS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM LAYERS; GESTATIONAL AGE; GLYCOPROTEINS; HYPOGLYCEMIC AGENTS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEOVASCULARIZATION, PHYSIOLOGIC; ORGAN SPECIFICITY; PLACENTA; PPAR GAMMA; PREGNANCY; THIAZOLIDINEDIONES;

EID: 77957285982     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2010-0131     Document Type: Article

References (49)

1. Desvergne B, Michalik L, Wahli W 2004 Be fit or be sick: peroxisome proliferator-activated receptors are down the road. Mol Endocrinol 18:1321-1332
2. Kliewer SA, Sundseth SS, Jones SA, Brown PJ, Wisely GB, Koble CS, Devchand P, Wahli W, Willson TM, Lenhard JM, Lehmann JM 1997 Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ. Proc Natl Acad Sci USA 94:4318-4323
3. Braissant O, Foufelle F, Scotto C, Dauça M, Wahli W 1996 Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-α, -β, and -γ in the adult rat. Endocrinology 137:354-366
4. Barak Y, Nelson MC, Ong ES, Jones YZ, Ruiz-Lozano P, Chien KR, Koder A, Evans RM 1999 PPARγ is required for placental, cardiac, and adipose tissue development. Mol Cell 4:585-595
5. Kubota N, Terauchi Y, Miki H, Tamemoto H, Yamauchi T, Komeda K, Satoh S, Nakano R, Ishii C, Sugiyama T, Eto K, Tsubamoto Y, Okuno A, Murakami K, Sekihara H, Hasegawa G, Naito M, Toyoshima Y, Tanaka S, Shiota K, Kitamura T, Fujita T, Ezaki O, Aizawa S, Kadowaki T 1999 PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol Cell 4:597-609
6. Rosen ED, Sarraf P, Troy AE, Bradwin G, Moore K, Milstone DS, Spiegelman BM, Mortensen RM 1999 PPARγ is required for the differentiation of adipose tissue in vivo and in vitro. Mol Cell 4:611-617
7. Kahn CR, Chen L, Cohen SE 2000 Unraveling the mechanism of action of thiazolidinediones. J Clin Invest 106:1305-1307
8. Staels B, Fruchart JC 2005 Therapeutic roles of peroxisome proliferator-activated receptor agonists. Diabetes 54:2460-2470 (Pubitemid 41134276)
9. Risau W 1997 Mechanisms of angiogenesis. Nature 386:671-674
10. Yancopoulos GD, Davis S, Gale NW, Rudge JS, Wiegand SJ, Holash J 2000 Vascular-specific growth factors and blood vessel formation. Nature 407:242-248
11. Folkman J, Merler E, Abernathy C, Williams G 1971 Isolation of a tumor factor responsible for angiogenesis. J Exp Med 133:275-288
12. Folkman J 2007 Angiogenesis: an organizing principle for drug discovery? Nat Rev Drug Discov 6:273-286
13. Klagsbrun M, D'Amore PA 1991 Regulators of angiogenesis. Annu Rev Physiol 53:217-239
14. Murray MJ, Lessey BA 1999 Embryo implantation and tumor metastasis: common pathways of invasion and angiogenesis. Semin Reprod Endocrinol 17:275-290
15. Torry RJ, Rongish BJ 1992 Angiogenesis in the uterus: potential regulation and relation to tumor angiogenesis. Am J Reprod Immunol 27:171-179
16. Fournier T, Tsatsaris V, Handschuh K, Evain-Brion D 2007 PPARs and the placenta. Placenta 28:65-76
17. Nadra K, Anghel SI, Joye E, Tan NS, Basu-Modak S, Trono D, Wahli W, Desvergne B 2006 Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor β/δ. Mol Cell Biol 26:3266-3281
18. Schaiff WT, Knapp Jr FF, Barak Y, Biron-Shental T, Nelson DM, Sadovsky Y 2007 Ligand-activated peroxisome proliferator activated receptor γ alters placental morphology and placental fatty acid uptake in mice. Endocrinology 148:3625-3634
19. Rieusset J, Seydoux J, Anghel SI, Escher P, Michalik L, Soon Tan N, Metzger D, Chambon P, Wahli W, Desvergne B 2004 Altered growth in male peroxisome proliferator-activated receptor γ (PPARγ) heterozygous mice: involvement of PPARγ in a negative feedback regulation of growth hormone action. Mol Endocrinol 18:2363-2377
20. Hayashi S, Lewis P, Pevny L, McMahon AP 2002 Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain. Mech Dev 119(Suppl 1):S97-S101 (Pubitemid 39658693)
21. Vincent SD, Robertson EJ 2003 Highly efficient transgene-independent recombination directed by a maternally derived SOX2CRE transgene. Genesis 37:54-56
22. Imai T, Takakuwa R, Marchand S, Dentz E, Bornert JM, Messaddeq N, Wendling O, Mark M, Desvergne B, Wahli W, Chambon P, Metzger D 2004 Peroxisome proliferator-activated receptor γ is required in mature white and brown adipocytes for their survival in the mouse. Proc Natl Acad Sci USA 101:4543-4547
23. Adamson SL, Lu Y, Whiteley KJ, Holmyard D, Hemberger M, Pfarrer C, Cross JC 2002 Interactions between trophoblast cells and the maternal and fetal circulation in the mouse placenta. Dev Biol 250:358-373
24. Nadra K, de Preux Charles AS, Médard JJ, Hendriks WT, Han GS, Grès S, Carman GM, Saulnier-Blache JS, Verheijen MH, Chrast R 2008 Phosphatidic acid mediates demyelination in Lpin1 mutant mice. Genes Dev 22:1647-1661
25. Tallquist MD, Soriano P 2000 Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function. Genesis 26:113-115
26. Duan SZ, Ivashchenko CY, Whitesall SE, D'Alecy LG, Duquaine DC, Brosius 3rd FC, Gonzalez FJ, Vinson C, Pierre MA, Milstone DS, Mortensen RM 2007 Hypotension, lipodystrophy, and insulin resistance in generalized PPARγ-deficient mice rescued from embryonic lethality. J Clin Invest 117:812-822
27. Duan SZ, Usher MG, Foley 4th EL, Milstone DS, Brosius 3rd FC, Mortensen RM 2010 Sex dimorphic actions of rosiglitazone in generalised peroxisome proliferator-activated receptor-γ(PPAR-γ)-deficient mice. Diabetologia 53:1493-1505
28. Lee SJ, Talamantes F, Wilder E, Linzer DI, Nathans D 1988 Trophoblastic giant cells of the mouse placenta as the site of proliferin synthesis. Endocrinology 122:1761-1768
29. Jackson D, Volpert OV, Bouck N, Linzer DI 1994 Stimulation and inhibition of angiogenesis by placental proliferin and proliferin-related protein. Science 266:1581-1584
30. Rosen ED, Walkey CJ, Puigserver P, Spiegelman BM 2000 Transcriptional regulation of adipogenesis. Genes Dev 14:1293-1307
31. Dalen KT, Schoonjans K, Ulven SM, Weedon-Fekjaer MS, Bentzen TG, Koutnikova H, Auwerx J, Nebb HI 2004 Adipose tissue expression of the lipid droplet-associating proteins S3-12 and perilipin is controlled by peroxisome proliferator-activated receptor-γ. Diabetes 53:1243-1252
32. Sherer DM, Abulafia O 2001 Angiogenesis during implantation, and placental and early embryonic development. Placenta 22:1-13
33. Ferrara N, Gerber HP, LeCouter J 2003 The biology of VEGF and its receptors. Nat Med 9:669-676
34. Soares MJ, Alam SM, Duckworth ML, Horseman ND, Konno T, Linzer DI, Maltais LJ, Nilsen-Hamilton M, Shiota K, Smith JR, Wallis M 2007 A standardized nomenclature for the mouse and rat prolactin superfamilies. Mamm Genome 18:154-156
35. Corbacho AM, Martínez De La Escalera G, Clapp C 2002 Roles of prolactin and related members of the prolactin/growth hormone/ placental lactogen family in angiogenesis. J Endocrinol 173:219-238
36. Bengtson NW, Linzer DI 2000 Inhibition of tumor growth by the antiangiogenic placental hormone, proliferin-related protein. Mol Endocrinol 14:1934-1943
37. Toft DJ, Rosenberg SB, Bergers G, Volpert O, Linzer DI 2001 Reactivation of proliferin gene expression is associated with increased angiogenesis in a cell culture model of fibrosarcoma tumor progression. Proc Natl Acad Sci USA 98:13055-13059
38. Antonson P, Schuster GU, Wang L, Rozell B, Holter E, Flodby P, Treuter E, Holmgren L, Gustafsson JA 2003 Inactivation of the nuclear receptor coactivator RAP250 in mice results in placental vascular dysfunction. Mol Cell Biol 23:1260-1268
39. Marx N, Bourcier T, Sukhova GK, Libby P, Plutzky J 1999 PPARγ activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression: PPARγ as a potential mediator in vascular disease. Arterioscler Thromb Vasc Biol 19:546-551
40. Xin X, Yang S, Kowalski J, Gerritsen ME 1999 Peroxisome proliferator- activated receptor γ ligands are potent inhibitors of angiogenesis in vitro and in vivo. J Biol Chem 274:9116-9121
41. Murata T, He S, Hangai M, Ishibashi T, Xi XP, Kim S, Hsueh WA, Ryan SJ, Law RE, Hinton DR 2000 Peroxisome proliferator-activated receptor-γ ligands inhibit choroidal neovascularization. Invest Ophthalmol Vis Sci 41:2309-2317
42. Panigrahy D, Singer S, Shen LQ, Butterfield CE, Freedman DA, Chen EJ, Moses MA, Kilroy S, Duensing S, Fletcher C, Fletcher JA, Hlatky L, Hahnfeldt P, Folkman J, Kaipainen A 2002 PPARγ ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis. J Clin Invest 110:923-932
43. Rodriguez TA, Sparrow DB, Scott AN, Withington SL, Preis JI, Michalicek J, Clements M, Tsang TE, Shioda T, Beddington RS, Dunwoodie SL 2004 Cited1 is required in trophoblasts for placental development and for embryo growth and survival. Mol Cell Biol 24:228-244
44. Zheng-Fischhöfer Q, Kibschull M, Schnichels M, Kretz M, Petrasch- Parwez E, Strotmann J, Reucher H, Lynn BD, Nagy JI, Lye SJ, Winterhager E, Willecke K 2007 Characterization of connexin31.1-deficient mice reveals impaired placental development. Dev Biol 312: 258-271
45. Raffel GD, Chu GC, Jesneck JL, Cullen DE, Bronson RT, Bernard OA, Gilliland DG 2009 Ott1 (Rbm15) is essential for placental vascular branching morphogenesis and embryonic development of the heart and spleen. Mol Cell Biol 29:333-341
46. Li Y, Behringer RR 1998 Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growth. Nat Genet 20: 309-311
47. Tanaka S, Oda M, Toyoshima Y, Wakayama T, Tanaka M, Yoshida N, Hattori N, Ohgane J, Yanagimachi R, Shiota K 2001 Placentomegaly in cloned mouse concepti caused by expansion of the spongiotrophoblast layer. Biol Reprod 65:1813-1821
48. Redman CW, Sargent IL 2005 Latest advances in understanding preeclampsia. Science 308:1592-1594
49. Kaufmann P, Black S, Huppertz B 2003 Endovascular trophoblast invasion: implications for the pathogenesis of intrauterine growth retardation and preeclampsia. Biol Reprod 69:1-7