-
1
-
-
0029099107
-
A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles
-
Fernandez-Salguero P, Hoffman SMG, Cholerton S et al. A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles. Am J Hum Genet 1995; 57: 651-60.
-
(1995)
Am J Hum Genet
, vol.57
, pp. 651-660
-
-
Fernandez-Salguero, P.1
Hoffman, S.M.G.2
Cholerton, S.3
-
2
-
-
0025022689
-
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
-
Yamano S, Tatsuno J, Gonzalez FJ. The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes. Biochemistry 1990; 29: 1322-9.
-
(1990)
Biochemistry
, vol.29
, pp. 1322-1329
-
-
Yamano, S.1
Tatsuno, J.2
Gonzalez, F.J.3
-
3
-
-
0034665139
-
Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
-
Su T, Bao Z, Zhang QY et al. Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Res 2000; 60: 5074-9.
-
(2000)
Cancer Res
, vol.60
, pp. 5074-5079
-
-
Su, T.1
Bao, Z.2
Zhang, Q.Y.3
-
4
-
-
0032939647
-
Expression of CYP2A genes in human liver and extrahepatic tissues
-
Koskela S, Hakkola J, Hukkanen J et al. Expression of CYP2A genes in human liver and extrahepatic tissues. Biochem Pharmacol 1999; 57: 1407-13.
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 1407-1413
-
-
Koskela, S.1
Hakkola, J.2
Hukkanen, J.3
-
5
-
-
0034212519
-
Expression and biotransformation enzymes in human fetal olfactory mucosa: potential roles in developmental toxicity
-
Gu J, Su Y, Chen QY et al. Expression and biotransformation enzymes in human fetal olfactory mucosa: potential roles in developmental toxicity. Toxicol Appl Pharmacol 2000; 165: 158-62.
-
(2000)
Toxicol Appl Pharmacol
, vol.165
, pp. 158-162
-
-
Gu, J.1
Su, Y.2
Chen, Q.Y.3
-
6
-
-
13444274285
-
Metabolism of nicotine and cotinine by human cytochrome P450 2A13
-
Bao Z, He XY, Ding X et al. Metabolism of nicotine and cotinine by human cytochrome P450 2A13. Drug Metab Dispos 2005; 33: 258-61.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 258-261
-
-
Bao, Z.1
He, X.Y.2
Ding, X.3
-
7
-
-
33750608093
-
CYP2A13 expressed in human bladder metabolically activates 4-aminobiphenyl
-
Nakajima M, Itoh M, Sakai H et al. CYP2A13 expressed in human bladder metabolically activates 4-aminobiphenyl. Int J Cancer 2006; 119: 2520-6.
-
(2006)
Int J Cancer
, vol.119
, pp. 2520-2526
-
-
Nakajima, M.1
Itoh, M.2
Sakai, H.3
-
8
-
-
41849093006
-
Human cytochrome P450 2A13 efficeintly metabolizes chemicals in air pollutants: naphthalene, styrene, and toluene
-
Fukami T, Katoh M, Yamazaki H et al. Human cytochrome P450 2A13 efficeintly metabolizes chemicals in air pollutants: naphthalene, styrene, and toluene. Chem Res Toxicol 2008; 21: 720-5.
-
(2008)
Chem Res Toxicol
, vol.21
, pp. 720-725
-
-
Fukami, T.1
Katoh, M.2
Yamazaki, H.3
-
9
-
-
33846279783
-
Requirement of aryl hydrocarbon receptor overexpression for CYP1B1 up-regulation and cell growth in human lung adenocarcinomas
-
Chang JT, Chang H, Chen PH et al. Requirement of aryl hydrocarbon receptor overexpression for CYP1B1 up-regulation and cell growth in human lung adenocarcinomas. Clin Cancer Res 2007; 13: 38-45.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 38-45
-
-
Chang, J.T.1
Chang, H.2
Chen, P.H.3
-
10
-
-
0030812372
-
Tumor-specific expression of cytochrome P450 CYP1B1
-
Murray GI, Taylor MC, McFadyen MCE et al. Tumor-specific expression of cytochrome P450 CYP1B1. Cancer Res 1997; 57: 3026-31.
-
(1997)
Cancer Res
, vol.57
, pp. 3026-3031
-
-
Murray, G.I.1
Taylor, M.C.2
McFadyen, M.C.E.3
-
12
-
-
33748918311
-
CYP2A13 in human respiratory tissues and lung cancers: an immunohistochemical study with a new peptide-specific antibody
-
Zhu LR, Thomas PE, Lu G et al. CYP2A13 in human respiratory tissues and lung cancers: an immunohistochemical study with a new peptide-specific antibody. Drug Metab Dispos 2006; 34: 1672-6.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 1672-1676
-
-
Zhu, L.R.1
Thomas, P.E.2
Lu, G.3
-
13
-
-
10044244648
-
*17 has an amino acid substitution (V365M) that decreases enzymatic activity in vitro and in vivo
-
*17 has an amino acid substitution (V365M) that decreases enzymatic activity in vitro and in vivo. Clin Pharmacol Ther 2004; 76: 519-27.
-
(2004)
Clin Pharmacol Ther
, vol.76
, pp. 519-527
-
-
Fukami, T.1
Nakajima, M.2
Yoshida, R.3
-
14
-
-
28144450359
-
CYP2A6 and CYP2B6 are involved in nornicotine formation from nicotine in humans: interindividual differences in these contributions
-
Yamanaka H, Nakajima M, Fukami T et al. CYP2A6 and CYP2B6 are involved in nornicotine formation from nicotine in humans: interindividual differences in these contributions. Drug Metab Dispos 2005; 33: 1811-8.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 1811-1818
-
-
Yamanaka, H.1
Nakajima, M.2
Fukami, T.3
-
15
-
-
33745137491
-
Recombinant enzymes overexpressed in bacteria show broad catalytic specificity of human cytochrome P450 2W1 and limited activity of human cytochrome P450 2S1
-
Wu ZL, Sohl CD, Shimada T et al. Recombinant enzymes overexpressed in bacteria show broad catalytic specificity of human cytochrome P450 2W1 and limited activity of human cytochrome P450 2S1. Mol Pharmacol 2006; 69: 2007-14.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 2007-2014
-
-
Wu, Z.L.1
Sohl, C.D.2
Shimada, T.3
-
17
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriopharge T4
-
Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriopharge T4. Nature 1970; 227: 680-5.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
18
-
-
21144437181
-
Metabolic activation of the tobacco carcinogen 4-(methylnitrosamino)-(3-pyridyl)-1-butanone by cytochrome P450 2A13 in human fetal nasal microsomes
-
Wong HL, Zhang X, Zhang QY et al. Metabolic activation of the tobacco carcinogen 4-(methylnitrosamino)-(3-pyridyl)-1-butanone by cytochrome P450 2A13 in human fetal nasal microsomes. Chem Res Toxicol 2005; 18: 913-8.
-
(2005)
Chem Res Toxicol
, vol.18
, pp. 913-918
-
-
Wong, H.L.1
Zhang, X.2
Zhang, Q.Y.3
-
19
-
-
35548981393
-
CYP2A13: variable expression and role in human lung microsomal metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
-
Zhang X, D'Agostino J, Wu H et al. CYP2A13: variable expression and role in human lung microsomal metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. J Pharmacol Exp Ther 2007; 323: 570-8.
-
(2007)
J Pharmacol Exp Ther
, vol.323
, pp. 570-578
-
-
Zhang, X.1
D'Agostino, J.2
Wu, H.3
-
20
-
-
33846794564
-
Expression of CYP2S1 in human hepatic stellate cells
-
Marek CJ, Tucker SJ, Koruth M et al. Expression of CYP2S1 in human hepatic stellate cells. FEBS Lett 2007; 581: 781-6.
-
(2007)
FEBS Lett
, vol.581
, pp. 781-786
-
-
Marek, C.J.1
Tucker, S.J.2
Koruth, M.3
-
21
-
-
0029868343
-
A comparative study of the risk factors for lung cancer in Guangdong, China
-
Wang SY, Hu YL, Wu YL et al. A comparative study of the risk factors for lung cancer in Guangdong, China. Lung Cancer 1996; 14 (Suppl 1): S99-105.
-
(1996)
Lung Cancer
, vol.14
, Issue.SUPPL. 1
-
-
Wang, S.Y.1
Hu, Y.L.2
Wu, Y.L.3
-
22
-
-
0026524519
-
Gender and histologic type variations in smoking-related risk of lung cancer
-
Brownson RC, Chang JC, Davis JR. Gender and histologic type variations in smoking-related risk of lung cancer. Epidemiology 1992; 3: 61-4.
-
(1992)
Epidemiology
, vol.3
, pp. 61-64
-
-
Brownson, R.C.1
Chang, J.C.2
Davis, J.R.3
-
23
-
-
0025993684
-
Cigarette smoking and lung cancer cell types
-
Morabia A, Wynder EL. Cigarette smoking and lung cancer cell types. Cancer (Phil) 1991; 68: 2074-8.
-
(1991)
Cancer (Phil)
, vol.68
, pp. 2074-2078
-
-
Morabia, A.1
Wynder, E.L.2
-
24
-
-
0027488025
-
Cigarette smoking and adenocarcinoma of the lung: the relevance of nicotine-derived N-nitrosamines
-
Hoffmann D, Rivenson A, Murphy SE et al. Cigarette smoking and adenocarcinoma of the lung: the relevance of nicotine-derived N-nitrosamines. J Smok Rel Disord 1993; 4: 165-89.
-
(1993)
J Smok Rel Disord
, vol.4
, pp. 165-189
-
-
Hoffmann, D.1
Rivenson, A.2
Murphy, S.E.3
-
25
-
-
0345707570
-
Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK
-
Wang H, Tan W, Hao B et al. Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK. Cancer Res 2003; 63: 8057-61.
-
(2003)
Cancer Res
, vol.63
, pp. 8057-8061
-
-
Wang, H.1
Tan, W.2
Hao, B.3
-
26
-
-
28544447343
-
CYP2A13, CYP2A6, and the risk of lung adenocarcinoma in a Japanese population
-
Kiyohara C, Takayama K, Nakanishi Y. CYP2A13, CYP2A6, and the risk of lung adenocarcinoma in a Japanese population. J Health Sci 2005; 51: 658-66.
-
(2005)
J Health Sci
, vol.51
, pp. 658-666
-
-
Kiyohara, C.1
Takayama, K.2
Nakanishi, Y.3
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