Conformational changes and substrate recognition in pseudomonas aeruginosa d-arginine dehydrogenase

Biochemistry

Volumn 49, Issue 39, 2010, Pages 8535-8545

  Fu, Guoxing ^a   Yuan, Hongling ^b   Li, Congran ^e   Lu, Chung Dar ^a,c   Gadda, Giovanni ^a,b,c,d   Weber, Irene T ^a,b,c  

^a Biology Department   (United States)

^b Chemistry Department   (United States)

^c Center for Drug Design   (United States)

^d GEORGIA STATE UNIVERSITY   (United States)

^e PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; BINDING MODES; CONFORMATIONAL CHANGE; D-AMINO ACID; FLAVIN-DEPENDENT; GUANIDINIUM; HYDROGEN BOND INTERACTION; IMIDAZOLE GROUP; IONIC INTERACTION; KETO ACIDS; KINETIC DATA; OXIDATIVE DEAMINATION; POSITIVELY CHARGED; PSEUDOMONAS AERUGINOSA; SIDE CHAINS; SUBSTRATE RECOGNITION; SUBSTRATE SPECIFICITY; SURFACE LOOPS; X RAY CRYSTAL STRUCTURES;

AMINO ACIDS; BINDING ENERGY; COMPLEXATION; CONFORMATIONS; ENZYMES; HYDROGEN; HYDROGEN BONDS; ORGANIC ACIDS; PHOSPHATASES;

CRYSTAL STRUCTURE;

BACTERIAL ENZYME; DEXTRO ARGININE; DEXTRO ARGININE DEHYDROGENASE; HISTIDINE; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; HYDROGEN BOND; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; STEADY STATE; X RAY CRYSTALLOGRAPHY;

AMINO ACID OXIDOREDUCTASES; ARGININE; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HISTIDINE; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PSEUDOMONAS AERUGINOSA; SUBSTRATE SPECIFICITY;

PSEUDOMONAS AERUGINOSA;

EID: 77957269392     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1005865     Document Type: Article

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