Tandem 5'-GA:GA-3' mismatches account for the high stability of the fold-back structures formed by the centromeric Drosophila dodeca-satellite

Journal of Molecular Biology

Volumn 277, Issue 4, 1998, Pages 757-762

  Ortiz Lombardía, Miguel ^a   Cortés, Alfred ^a   Huertas, Dori ^a   Eritja, Ramón ^b   Azorín, Fernando ^a  

^a Dept Biol Molec I Cellular C ^*  (Spain)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Centromere; G A mismatch; Non B DNA structures; Purine purine interactions; Satellite DNA

Indexed keywords

PURINE; SATELLITE DNA;

ARTICLE; BASE MISPAIRING; CENTROMERE; DNA STRUCTURE; DROSOPHILA; GEL ELECTROPHORESIS; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; TANDEM REPEAT;

DROSOPHILA;

EID: 0032502802     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.1646     Document Type: Article

References (26)

1. Abad J.P., Carmena M., Baars S., Saunders R.D.C., Glover D.M., Ludeña P., Sentis C., Tyler-Smith C., Villasante A. Dodeca-satellite a conserved G + C-rich satellite from the centromeric heterochromatin of Drosophila melanogaster. Proc. Natl Acad. Sci. USA. 89:1992;4663-4667
2. Aboul-ela F., Koh D., Tinoco I. Jr. Base-base mismatches. Thermodynamics of double helix formation for dCA3XA3G + dCT3YT3G (X, Y = A,C,G,T). Nucl. Acids Res. 13:1985;4811-4824
3. Castasti P., Gupta G., Garcia A.E., Hong L., Yau P., Moyzis R.K., Bradbury E.M. Unusual structures of tandem repetitive sequences located at human centromeres. Biochemistry. 33:1994;3819-3830
4. Carmena M., Abad J.P., Villasante A., González C. The Drosophila melanogaster dodecasatellite sequence is closely linked to the centromere and can form connections between sister chromatids during mitosis. J. Cell. Sci. 105:1993;41-50
5. Cheng J.-W., Chou S.-H., Reid B.R. Base pairing geometry in GA mismatches depends entirely on the neighbouring sequence. J. Mol. Biol. 228:1992;1037-1041
6. 2 motif unpaired guanosines stacked between sheared G·A pairs in solution. J. Mol. Biol. 244:1994;259-268
7. Chou S.-H., Zhu L., Reid B.R. Sheared purine·purine pairing in Biology. J. Mol. Biol. 267:1997;1055-1067
8. Ebel S., Lane A.N., Brown T. Very stable mismatch duplexes structural and thermodynamic studies on tandem G·A mismatches in DNA. Biochemistry. 31:1992;12083-12086
9. Ferrer N., Azorín F., Villasante A., Gutiérrez C., Abad J.P. Centromeric dodeca-satellite DNA sequences form fold-back structures. J. Mol. Biol. 245:1995;8-21
10. Grady D.L., Ratliff R.L., Robinson D.L., McCanlies E.C., Meyne J., Moyzis R.K. Highly conserved repetitive DNA sequences are present at human centromeres. Proc. Natl Acad. Sci. USA. 89:1992;1695-1699
11. Harrington J.J., van Bokkelen G., Mays R.W., Gustashaw K., Willard H.F. Formation of de novo centromeres and construction of first-generation human artificial chromosomes. Nature Genet. 15:1997;345-355
12. n sequence forms stable structures with unusual base pairs. FEBS Letters. 347:1994;99-103
13. Karpen G.H. Molecular genetics of chromosome inheritance in Drosophila. Proceedings of Juan March Workshops on Biology. 58:1996;37-39
14. Karpen G., Allshire R. The case for epigenetic effects on centromere identity and function. Trends Genet. 13:1997;489-496
15. Ke S.-H., Wartell R.M. The thermal stability of DNA fragments with tandem mismatches at a d(CXYG)·d(CY′X′G) site. Nucl. Acids Res. 24:1996;707-712
16. Kipling D., Mitchell A.R., Masumoto H., Wilson H.E., Nicol L., Cooke H.J. CENP-B binds a novel centromeric sequence in the asian mouse Mus caroli. Mol. Cell. Biol. 15:1995;4009-4021
17. Li Y., Zon G., Wilson W.D. Thermodynamics of DNA duplexes with adjacent G·A mismatches. Biochemistry. 30:1991;7566-7572
18. Lohe A.R., Hilliker A.J., Roberts P.A. Mapping simple repeated DNA sequences in heterochromatin of Drosophila melanogaster. Genetics. 134:1993;1149-1174
19. Losada A., Abad J.P., Villasante A. Organization of DNA sequences near the centromere of Drosophila melanogaster Y chromosome. Chromosoma. 1997;. in the press
20. Maniatis T., Jeffery A., van de Sande H. Chain length determination of small double and single-stranded DNA molecules by polyacrylamide gel electrophoresis. Biochemistry. 14:1975;3787-3794
21. Masumoto H., Masukata H., Muro Y., Nozaki N., Okazaki T. A human centromere antigen (CENP-B) interacts with a short specific sequence in alphoid DNA, a human centromeric satellite. J. Cell. Biol. 109:1989;1963-1973
22. Murphy T., Karpen G.H. Localization of centromere function in a Drosophila minichromosome. Cell. 82:1995;599-609
23. Pluta A.F., Mackay A.M., Ainsztein A.M., Goldberg I.G., Earnshaw W.C. The centromere hub of chromosomal activities. Science. 270:1995;1591-1594
24. du Sart D., Cancilla M.R., Earle E., Mao J.-I., Saffery R., Taontin K.M., Kalitsis P., Martyn J., Barry A.E., Choo K.H.A. A functional neo-centromere formed through activation of a latent human centromere and consisting of non-alpha-satellite DNA. Nature Genet. 16:1997;144-153
25. Tyler-Smith C., Willard H.F. Mammalian chromosome structure. Curr. Opin. Genet. Develop. 3:1993;390-397
26. Voullaire L.E., Slater H.R., Petrovic V., Choo K.H.A. A functional centromere with no detectable alpha-satellite, satellite III, or CENP-B protein activation of a latent centromere? Am. J. Hum. Genet. 52:1993;1153-1163