Distinct migratory and cytokine responses of human microglia and macrophages to ATP

Brain, Behavior, and Immunity

Volumn 24, Issue 8, 2010, Pages 1241-1248

  Lambert, Caroline ^a   Ase, Ariel R ^a   Séguéla, Philippe ^a   Antel, Jack P ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Adenosine; ADP; ATP; CCL2; Cytokines; Human; Macrophages; Microglia; Migration; Monocytes

Indexed keywords

ADENOSINE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; PURINERGIC RECEPTOR STIMULATING AGENT; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL MIGRATION; CHEMOKINESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GROUPS BY AGE; HUMAN; HUMAN CELL; IMMUNOMODULATION; MACROPHAGE MIGRATION; MICROGLIA; MONOCYTE; PRIORITY JOURNAL;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; BRAIN; CELL MOVEMENT; CHEMOKINE CCL2; CYTOKINES; FEMALE; FETUS; FLOW CYTOMETRY; HUMANS; INDICATORS AND REAGENTS; INTERLEUKIN-10; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICROGLIA; PREGNANCY; PURINERGIC P2Y RECEPTOR AGONISTS; RECEPTORS, PURINERGIC P2Y1; THIONUCLEOTIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77957241864     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2010.02.010     Document Type: Article

References (43)

1. Aurivillius M., Hansen O.C., Lazrek M.B., Bock E., Obrink B. The cell adhesion molecule Cell-CAM 105 is an ecto-ATPase and a member of the immunoglobulin superfamily. FEBS Lett. 1990, 264:267-269.
2. Bianco F., Ceruti S., Colombo A., Fumagalli M., Ferrari D., Pizzirani C., Matteoli M., Di Virgilio F., Abbracchio M.P., Verderio C. A role for P2X7 in microglial proliferation. J. Neurochem. 2006, 99:745-758.
3. Chakfe Y., Seguin R., Antel J.P., Morissette C., Malo D., Henderson D., Seguela P. ADP and AMP induce interleukin-1beta release from microglial cells through activation of ATP-primed P2X7 receptor channels. J. Neurosci. 2002, 22:3061-3069.
4. Choi H.B., Ryu J.K., Kim S.U., McLarnon J.G. Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain. J. Neurosci. 2007, 27:4957-4968.
5. D'Souza S., Alinauskas K., McCrea E., Goodyer C., Antel J.P. Differential susceptibility of human CNS-derived cell populations to TNF-dependent and independent immune-mediated injury. J. Neurosci. 1995, 15:7293-7300.
6. Davalos D., Grutzendler J., Yang G., Kim J.V., Zuo Y., Jung S., Littman D.R., Dustin M.L., Gan W.B. ATP mediates rapid microglial response to local brain injury in vivo. Nat. Neurosci. 2005, 8:752-758.
7. Deng Y.Y., Lu J., Ling E.A., Kaur C. Monocyte chemoattractant protein-1 (MCP-1) produced via NF-kappaB signaling pathway mediates migration of amoeboid microglia in the periventricular white matter in hypoxic neonatal rats. Glia 2009, 57:604-621.
8. Di Virgilio F., Ferrari D., Falzoni S., Chiozzi P., Munerati M., Steinberg T.H., Baricordi O.R. P2 purinoceptors in the immune system. Ciba Found Symp. 1996, 198:290-302. Discussion 302-305.
9. Duan Y., Sahley C.L., Muller K.J. ATP and NO dually control migration of microglia to nerve lesions. Dev. Neurobiol. 2009, 69:60-72.
10. Elliott M.R., Chekeni F.B., Trampont P.C., Lazarowski E.R., Kadl A., Walk S.F., Park D., Woodson R.I., Ostankovich M., Sharma P., Lysiak J.J., Harden T.K., Leitinger N., Ravichandran K.S. Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature 2009, 461:282-286.
11. Fantuzzi L., Borghi P., Ciolli V., Pavlakis G., Belardelli F., Gessani S. Loss of CCR2 expression and functional response to monocyte chemotactic protein (MCP-1) during the differentiation of human monocytes: role of secreted MCP-1 in the regulation of the chemotactic response. Blood 1999, 94:875-883.
12. Farber K., Markworth S., Pannasch U., Nolte C., Prinz V., Kronenberg G., Gertz K., Endres M., Bechmann I., Enjyoji K., Robson S.C., Kettenmann H. The ectonucleotidase cd39/ENTPDase1 modulates purinergic-mediated microglial migration. Glia 2008, 56:331-341.
13. Fedoroff S. Protocols for Neural Cell Culture Humana Press 1992, Saskatoon, p. 192.
14. Ferrari D., Chiozzi P., Falzoni S., Dal Susino M., Collo G., Buell G., Di Virgilio F. ATP-mediated cytotoxicity in microglial cells. Neuropharmacology 1997, 36:1295-1301.
15. Ferrari D., Chiozzi P., Falzoni S., Dal Susino M., Melchiorri L., Baricordi O.R., Di Virgilio F. Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages. J. Immunol. 1997, 159:1451-1458.
16. Ferrari D., Pizzirani C., Adinolfi E., Lemoli R.M., Curti A., Idzko M., Panther E., Di Virgilio F. The P2X7 receptor: a key player in IL-1 processing and release. J. Immunol. 2006, 176:3877-3883.
17. Hasko G., Kuhel D.G., Salzman A.L., Szabo C. ATP suppression of interleukin-12 and tumour necrosis factor-alpha release from macrophages. Br. J. Pharmacol. 2000, 129:909-914.
18. Hassan N.F., Campbell D.E., Rifat S., Douglas S.D. Isolation and characterization of human fetal brain-derived microglia in in vitro culture. Neuroscience 1991, 41:149-158.
19. Haynes S.E., Hollopeter G., Yang G., Kurpius D., Dailey M.E., Gan W.B., Julius D. The P2Y12 receptor regulates microglial activation by extracellular nucleotides. Nat. Neurosci. 2006, 9:1512-1591.
20. Honda S., Sasaki Y., Ohsawa K., Imai Y., Nakamura Y., Inoue K., Kohsaka S. Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors. J. Neurosci. 2001, 21:1975-1982.
21. Hooper C., Pinteaux-Jones F., Fry V.A., Sevastou I.G., Baker D., Heales S.J., Pocock J.M. Differential effects of albumin on microglia and macrophages; implications for neurodegeneration following blood-brain barrier damage. J. Neurochem. 2009, 109:694-705.
22. Jack C.S., Arbour N., Blain M., Meier U.C., Prat A., Antel J.P. Th1 polarization of CD4+ T cells by Toll-like receptor 3-activated human microglia. J. Neuropathol. Exp. Neurol. 2007, 66:848-859.
23. Jarvis M.F., Khakh B.S. ATP-gated P2X cation-channels. Neuropharmacology 2009, 56:208-215.
24. Lambert C., Desbarats J., Arbour N., Hall J.A., Olivier A., Bar-Or A., Antel J.P. Dendritic cell differentiation signals induce anti-inflammatory properties in human adult microglia. J. Immunol. 2008, 181:8288-8297.
25. Mahad D., Callahan M.K., Williams K.A., Ubogu E.E., Kivisakk P., Tucky B., Kidd G., Kingsbury G.A., Chang A., Fox R.J., Mack M., Sniderman M.B., Ravid R., Staugaitis S.M., Stins M.F., Ransohoff R.M. Modulating CCR2 and CCL2 at the blood-brain barrier: relevance for multiple sclerosis pathogenesis. Brain 2006, 129:212-223.
26. Mahad D.J., Ransohoff R.M. The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). Semin. Immunol. 2003, 15:23-32.
27. Miller A.M., Stella N. Microglial cell migration stimulated by ATP and C5a involve distinct molecular mechanisms: quantification of migration by a novel near-infrared method. Glia 2009, 57:875-883.
28. Myrtek D., Muller T., Geyer V., Derr N., Ferrari D., Zissel G., Durk T., Sorichter S., Luttmann W., Kuepper M., Norgauer J., Di Virgilio F., Virchow J.C., Idzko M. Activation of human alveolar macrophages via P2 receptors: coupling to intracellular Ca2+ increases and cytokine secretion. J. Immunol. 2008, 181:2181-2188.
29. Newman E.A. Propagation of intercellular calcium waves in retinal astrocytes and Muller cells. J. Neurosci. 2001, 21:2215-2223.
30. Ohsawa K., Irino Y., Nakamura Y., Akazawa C., Inoue K., Kohsaka S. Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis. Glia 2007, 55:604-616.
31. Schilling M., Besselmann M., Muller M., Strecker J.K., Ringelstein E.B., Kiefer R. Predominant phagocytic activity of resident microglia over hematogenous macrophages following transient focal cerebral ischemia: an investigation using green fluorescent protein transgenic bone marrow chimeric mice. Exp. Neurol. 2005, 196:290-297.
32. Schnurr M., Toy T., Shin A., Wagner M., Cebon J., Maraskovsky E. Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway. Blood 2005, 105:1582-1589.
33. Seo D.R., Kim K.Y., Lee Y.B. Interleukin-10 expression in lipopolysaccharide-activated microglia is mediated by extracellular ATP in an autocrine fashion. Neuroreport 2004, 15:1157-1161.
34. Seo D.R., Kim S.Y., Kim K.Y., Lee H.G., Moon J.H., Lee J.S., Lee S.H., Kim S.U., Lee Y.B. Cross talk between P2 purinergic receptors modulates extracellular ATP-mediated interleukin-10 production in rat microglial cells. Exp. Mol. Med. 2008, 40:19-26.
35. Simpson J., Rezaie P., Newcombe J., Cuzner M.L., Male D., Woodroofe M.N. Expression of the beta-chemokine receptors CCR2, CCR3 and CCR5 in multiple sclerosis central nervous system tissue. J. Neuroimmunol. 2000, 108:192-200.
36. Straub R.H., Mayer M., Kreutz M., Leeb S., Scholmerich J., Falk W. Neurotransmitters of the sympathetic nerve terminal are powerful chemoattractants for monocytes. J. Leukoc. Biol. 2000, 67:553-558.
37. Tanuma N., Sakuma H., Sasaki A., Matsumoto Y. Chemokine expression by astrocytes plays a role in microglia/macrophage activation and subsequent neurodegeneration in secondary progressive multiple sclerosis. Acta Neuropathol. 2006, 112:195-204.
38. Trautmann A. Extracellular ATP in the immune system: more than just a " danger signal" Sci. Signal 2009, 2:pe6.
39. Williams K., Bar-Or A., Ulvestad E., Olivier A., Antel J.P., Yong V.W. Biology of adult human microglia in culture: comparisons with peripheral blood monocytes and astrocytes. J. Neuropathol. Exp. Neurol. 1992, 51:538-549.
40. Wong C.W., Christen T., Roth I., Chadjichristos C.E., Derouette J.P., Foglia B.F., Chanson M., Goodenough D.A., Kwak B.R. Connexin37 protects against atherosclerosis by regulating monocyte adhesion. Nat. Med. 2006, 12:950-954.
41. Yegutkin G.G., Mikhailov A., Samburski S.S., Jalkanen S. The detection of micromolar pericellular ATP pool on lymphocyte surface by using lymphoid ecto-adenylate kinase as intrinsic ATP sensor. Mol. Biol. Cell 2006, 17:3378-3385.
42. Zhang J., Shi X.Q., Echeverry S., Mogil J.S., De Koninck Y., Rivest S. Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain. J. Neurosci. 2007, 27:12396-12406.
43. Zheng L.M., Zychlinsky A., Liu C.C., Ojcius D.M., Young J.D. Extracellular ATP as a trigger for apoptosis or programmed cell death. J. Cell. Biol. 1991, 112:279-288.