ENU mutagenesis screening for dominant behavioral mutations based on normal control data obtained in home-cage activity, open-field, and passive avoidance tests

Experimental Animals

Volumn 59, Issue 4, 2010, Pages 495-510

  Wada, Yumiko ^a,c   Furuse, Tamio ^a   Yamada, Ikuko ^a   Masuya, Hiroshi ^a   Kushida, Tomoko ^a   Shibukawa, Yoko ^a   Nakai, Yuji ^a   Kobayashi, Kimio ^a   Kaneda, Hideki ^a   Gondo, Yoichi ^a   Noda, Tetsuo ^a   Shiroishi, Toshihiko ^b   Wakana, Shigeharu ^a  

^a RIKEN BIORESOURCE CENTER   (Japan)

^b NATIONAL INSTITUTE OF GENETICS   (Japan)

^c Kyushu Lutheran College   (Japan)

Author keywords

Behavior; ENU; Mice; Mutagenesis; Mutants

Indexed keywords

ETHYLNITROSOUREA; ALKYLATING AGENT; MUTAGENIC AGENT;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR DISORDER; CONTROLLED STUDY; FEMALE; GENE MUTATION; GENETIC SCREENING; GENOTOXICITY; HYPERACTIVITY; MALE; MOUSE; MOUSE MUTANT; MUTAGENESIS; NONHUMAN; OPEN FIELD TEST; PASSIVE AVOIDANCE; PHENOTYPE; PROGENY; STRAIN DIFFERENCE; WILD TYPE; ANIMAL; AVOIDANCE BEHAVIOR; C57BL MOUSE; CBA MOUSE; DOMINANT GENE; DRUG EFFECTS; EXPLORATORY BEHAVIOR; GENE EXPRESSION REGULATION; GENETIC VARIABILITY; GENETICS; INBREEDING; MAZE TEST; MOTOR ACTIVITY; MUTATION; PHYSIOLOGY; REFERENCE VALUE;

MUS;

ALKYLATING AGENTS; ANIMALS; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; ETHYLNITROSOUREA; EXPLORATORY BEHAVIOR; FEMALE; GENE EXPRESSION REGULATION; GENES, DOMINANT; GENETIC TESTING; GENETIC VARIATION; INBREEDING; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MOTOR ACTIVITY; MUTAGENESIS; MUTAGENS; MUTATION; REFERENCE VALUES;

EID: 77957236660     PISSN: 13411357     EISSN: None     Source Type: Journal    
DOI: 10.1538/expanim.59.495     Document Type: Article

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