Blunted HPA axis responsiveness to stress in atopic patients is associated with the acuity and severeness of allergic inflammation

Brain, Behavior, and Immunity

Volumn 24, Issue 8, 2010, Pages 1347-1353

  Buske Kirschbaum, A ^a   Ebrecht, M ^b   Hellhammer, D H ^c  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b BRISTOL MYERS SQUIBB   (United States)

^c UNIVERSITY OF TRIER   (Germany)

Author keywords

Chronic (allergic) inflammation; Cortisol; Hypothalamus pituitary adrenal (HPA) axis; Seasonal allergic rhinitis (SAR); Stress

Indexed keywords

HYDROCORTISONE;

ADULT; ALLERGY; ARTICLE; ATOPY; BASOPHIL; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EOSINOPHIL; HAY FEVER; HORMONE RESPONSE; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INFLAMMATION; LEUKOCYTE COUNT; MALE; POLLEN ALLERGY; PRIORITY JOURNAL; SEASONAL VARIATION; SOCIAL STRESS; STRESS; SYMPTOMATOLOGY; TRIER SOCIAL STRESS TEST;

ADULT; FEMALE; HUMANS; HYDROCORTISONE; HYPERSENSITIVITY, IMMEDIATE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; IMMUNOGLOBULIN E; INFLAMMATION; LEUKOCYTE COUNT; LEUKOCYTES; MALE; PITUITARY-ADRENAL SYSTEM; POLLEN; RHINITIS, ALLERGIC, SEASONAL; SOCIAL ENVIRONMENT; STRESS, PSYCHOLOGICAL;

EID: 77957232336     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2010.06.013     Document Type: Article

References (48)

1. Akdis C.M. New insights into mechanisms of immunoregulation in 2007. J. Allergy Clin. Immunol. 2008, 122:700-709.
2. Ball T.H. Cortisol circadian rhythm and stress responses in infants at risk of allergic disease. Neuroimmunomodulation 2006, 13:294-300.
3. Blaiss M.S. Pediatric allergic rhinitis: physical and mental complications. Allergy Asthma Proc. 2008, 29:1-6.
4. Borish L. Allergic rhinitis: systemic inflammation and implications for management. J. Allergy Clin. Immunol. 2003, 112:1021-1031.
5. Bornstein S.R., Rutkowski H. The adrenal hormone metabolism in the immune/inflammatory reaction. Endocr. Res. 2002, 28:719-728.
6. Borres M.P. Allergic rhinitis: more than just a stuffy nose. Acta Paediatr. 2009, 98:1088-1092.
7. Bousquet J., Reid J., van Weel C., Baena Cagnani C., Canonica G.W., Demoly P., Denburg J., Fokkens W.J., Grouse L., Mullol K., Ohta K., Schermer T., Valovirta E., Zhong N., Zuberbier T. Allergic rhinitis management pocket reference. Allergy 2008, 63:990-996.
8. Buske-Kirschbaum A., Geiben A., Höllig H., Morschhäuser E., Hellhammer D. Altered responsiveness of the hypothalamus-pituitary-adrenal axis and the sympathetic adrenomedullary system to stress in patients with atopic dermatitis. J. Clin. Endocrinol. Metab. 2002, 87:4245-4251.
9. Buske-Kirschbaum A., Gierens A., Höllig H., Hellhammer D.H. Stress-induced immunomodulation is altered in patients with atopic dermatitis. J. Neuroimmunol. 2002, 129:161-167.
10. Buske-Kirschbaum A., von Auer K., Krieger S., Weis S., Rauh W., Hellhammer D. Blunted cortisol responses to psychosocial stress in asthmatic children: a general feature of atopic disease?. Psychosom. Med. 2003, 65:806-810.
11. Buske-Kirschbaum A., Fischbach S., Rauh W., Hanker J., Hellhammer D.H. Increased responsiveness of the hypothalamus-pituitary-adrenal (HPA) axis to stress in newborns with atopic disposition. Psychoneuroendocrinology 2004, 29:705-711.
12. Buske-Kirschbaum A. Endocrine and immune responses in chronic inflammatory skin disorder (atopic dermatitis). Psychoneuroimmunology 2007, 975-991. Academic Press, San Diego. 4th ed. Ader (Ed.).
13. Carr W.W., Nelson M.R., Hadley J.A. Managing rhinitis: strategies for improved patients outcomes. Allergy Asthma Proc. 2008, 29:349-357.
14. Chesnokova V., Melmed S. Minireview: neuro-immuno-endocrine modulation of the hypothalamic-pituitary-adrenal (HPA) axis by gp130 signaling molecules. Endocrionology 2002, 143:1571-1574.
15. Clow A., Thorn L., Evans P., Hucklebridge F. The awakening cortisol response: methodological issues and significance. Stress 2004, 7:29-37.
16. Dantzer R., Kelley K.W. Twenty years of research on cytokine-induced sickness behaviour. Brain, Behav., Immun. 2007, 21:153-160.
17. Dickerson S.S., Kemeny M.E. Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research. Psychol. Bull. 2004, 130:355-391.
18. Dressendörfer R.A., Kirschbaum C., Rohde W., Stahl F., Strasburger C.J. Synthesis of a cortisol-biotin conjugate and evaluation as tracer in an immunoassay for salivary cortisol measurement. J. Steroid Biochem. Mol. Biol. 1990, 43:83-692.
19. Elenkov I.J., Chrousos G.P. Stress hormones, proinflammatory and anti-inflammatory cytokines, and autoimmunity. Ann. N. Y. Acad. Sci. 2002, 966:290-303.
20. Eskandari F., Sternberg E.M. Neural-immune interactions in health and disease. Ann. N. Y. Acad. Sci. 2002, 966:20-27.
21. European Environement and Health Information System (EHNIS), 2007. Fact sheet, 3.1.
22. Fries E., Dettenborn L., Kirschbaum C. The cortisol awakening response (CAR): facts and future directions. Int. J. Psychophysiol. 2009, 72:67-73.
23. Gelfand E.W. Inflammatory mediators in allergic rhinitis. J. Allergy Clin. Immunol. 2004, 114:S135-S138.
24. Goebel M.U., Czolbe F., Becker H., Janssen O.E., Schedlowski M., Limmroth V. Effects of interferon-beta 1a on the hypothalamus-pituitary-adrenal axis, leukocyte distribution and mood states in multiple sclerosis patients: results of a 1-year follow-up study. Eur. Neurol. 2005, 53:182-187.
25. Gold M.S., Kemp A.S. Atopic disorders in childhood. Med. J. Aust. 2005, 182:298-304.
26. Hartgerink-Lutgens I., Vermeeren A., Vuurman E., Kremer B. Disturbed cognitive functions after nasal provocation in patients with seasonal allergic rhinitis. Clin. Exp. Allergy 2009, 39:500-508.
27. Heesen C., Gold S.M., Huitinga I., Reul J.M. Stress and the hypothalamic-pituitary-adrenal axis function in experimental autoimmune encephalomyelitits and multiple sclerosis-a review. Psychoneuroendocrinology 2007, 32:604-618.
28. Hughes, T.K., Cadet, P., Rady, P.L., Tyring, S.K., Chin, R., Smith, E.M., 1994 Evidence for the production and action of interleukin-10 in pituitary cells. Cell Mol. Neurobiol. 14, 59-69.
29. Juliusson S., Pipkorn U., Karlsson G., Enerback L. Mast cells and eosinophils in the allergic mucosa response to allergen challenge. Changes in distribution and signs of activation in relation to symptoms. J. Allergy Clin. Immunol. 1992, 90:898-909.
30. Kalogeromitros D., Syrigou E.K.I., Makris M., Kempuraj D., Stavianeas N.G., Vasiadi M., Theoharides T.C. Nasal provocation of patients with allergic rhinitis and the hypothalamus-pituitary-adrenal axis. Ann. Allergy Asthma Immunol. 2007, 98:269-273.
31. Kirschbaum C., Pirke K.M., Hellhammer D.H. The 'Trier Social Stress Test'- a tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology 1993, 28:76-81.
32. Kirschbaum C., Kudielka B.M., Gaab J., Schommer N.C., Hellhammer D.H. Impact of gender, menstrual cycle phase, and oral contraceptives on the activity of the hypothalamus-pituitary-adrenal axis. Psychosom. Med. 1999, 61:154-162.
33. Mancini A.J., Kaulback K., Chamlin S.L. The socioeconomic impact of atopic dermatitis in the United States: a systematic review. Pediatr. Dermatol. 2008, 25:1-6.
34. Naclerio R.M., Baroody F.M., Kagey-Sobotka A., Lichtenstein M. Basophils and eosinophils in allergic rhinits. J. Allergy Clin. Immunol. 1994, 94:1303-1309.
35. Nolten W.E., Goldstein D., Lindstrom M., McKenna M.V., Carson I.H., Trump D.L., Schiller J., Borden E.C., Ehrlich E.N. Effects of cytokines on the pituitary-adrenal axis in cancer patients. J. Interferon Res. 1993, 13:349-357.
36. Opp M.R., Smith E.M., Hughes T.K. Interleukin-10 (cytokine synthesis inhibitory factor) acts in the central nervous system of rats to reduce sleep. J. Neuroimmunol. 1995, 60:165-168.
37. Pipkorn U., Karlsson G., Enerback L. The cellular response of the human allergic mucosa to natural allergen exposure. J. Allergy Clin. Immunol. 1988, 82:1046-1054.
38. Prüssner J.C., Kirschbaum C., Meindlschmid G., Hellhammer D.H. Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change. Psychoneuroendocrinology 2003, 28:916-931.
39. Rivier C. The hypothalamus-pituitary-adrenal axis to immune signals. Psychoneuroimmunology 2000, 633-648. Adademic Press, San Diego. R. Ader, D.L. Felten, N. Cohen (Eds.).
40. Rohleder N., Kirschbaum C. The hypothalamus-pituitary-adrenal (HPA) axis in habitual smokers. Int. J. Psychophysiol. 2006, 59:236-243.
41. Rosenwasser L. New insights into the pathophysiology of allergic rhinitis. Allergy Asthma Proc. 2007, 28:10-15.
42. Salib R.J., Drake-Lee A., Howarth P.H. Allergic rhinitis: past, present and future. Clin. Otolarygnol. 2003, 28:291-303.
43. Sicherer S.H., Leung D.Y.M. Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2007. J. Allergy Clin. Immunol. 2008, 121:1351-1358.
44. Smith E.M., Cadet P., Stefano G.P., Opp M.R., Hughes T.K. IL-10 as a mediator in the HPA axis and brain. J. Neuroimmunol. 1999, 100:140-148.
45. Stefano G.B., Rodriguez M., Glass R., Cesares F., Hughes T.K., Bilfinger T.V. Interleukin-10 stimulation of corticotrophin releasing factor in the median eminence in rats. Evidence for dependence upon nitric oxide production. Neurosci. Letter 1998, 256:167-170.
46. Wang D.Y., Clement P. Pathogenic mechanisms underlying the clinical symptoms of allergic rhinitis. Am. J. Rhinol. 2000, 14:325-333.
47. Wright R.J. Stress and atopic disorders. J. Allergy Clin. Immunol. 2005, 116:1301-1306.
48. Yarlagadda A., Alfson E., Clayton A. The blood brain barrier and the role of cytokines in neuropsychiatry. Psychiatry 2009, 6:18-22.