Peptides in low molecular weight fraction of serum associated with hepatocellular carcinoma

Disease Markers

Volumn 29, Issue 1, 2010, Pages 11-20

  An, Yanming ^a   Bekesova, Slavka ^a   Edwards, Nathan ^b   Goldman, Radoslav ^a,b  

^a GEORGETOWN UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

biliverdin diglucuronide; complement; Hepatocellular carcinoma; mass spectrometry; serum

Indexed keywords

BILIVERDIN; BLOOD CLOTTING FACTOR 13; FIBRINOPEPTIDE; PROTEIN C4ALPHA; UNCLASSIFIED DRUG; ZYXIN;

AGED; AMINO ACID SEQUENCE; ARTICLE; HUMAN; INTERMETHOD COMPARISON; LIVER CELL CARCINOMA; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION;

EID: 77957229036     PISSN: 02780240     EISSN: None     Source Type: Journal    
DOI: 10.3233/DMA-2010-0721     Document Type: Article

References (53)

1. F.X. Bosch, J. Ribes, M. Diaz and R. Cleries, Primary liver cancer: worldwide incidence and trends, Gastroenterology 127 (2004), S5-S16. (Pubitemid 39423365)
2. H. Tammen, I. Schulte, R. Hess, C. Menzel, M. Kellmann and P. SchulzKnappe, Prerequisites for peptidomic analysis of blood samples: I. Evaluation of blood specimen qualities and determination of technical performance characteristics, Comb Chem High Throughput Screen 8 (2005), 725-733. (Pubitemid 41771573)
3. H.B. el Serag, Hepatocellular carcinoma: recent trends in the United States, Gastroenterology 127 (2004), S27-S34. (Pubitemid 39423367)
4. H.B. el Serag and A.C. Mason, Rising incidence of hepatocellular carcinoma in the United States, N Engl J Med 340 (1999), 745-750. (Pubitemid 29114292)
5. J.B. Wong, G.M. McQuillan, J.G. McHutchison and T. Poynard, Estimating future hepatitis C morbidity, mortality, and costs in the United States, Am J Public Health 90 (2000), 1562-1569.
6. T.J. Liang and T.Heller, Pathogenesis of hepatitis Cassociated hepatocellular carcinoma, Gastroenterology 127 (2004), S62-S71. (Pubitemid 39423371)
7. T.J. Liang, L.J. Jeffers,K.R. Reddy,M.DeMedina, I.T. Parker, H. Cheinquer, V. Idrovo, A. Rabassa and E.R. Schiff, Viral pathogenesis of hepatocellular carcinoma in the United States, Hepatology 18 (1993), 1326-1333. (Pubitemid 23348417)
8. J.C. Sheu, J.L. Sung, D.S. Chen,M.Y. Lai, T.H.Wang, J.Y.Yu, P.M.Yang, C.N. Chuang, P.C. Yang and C.S. Lee, Early detection of hepatocellular carcinoma by realtime ultrasonography. A prospective study, Cancer 56 (1985), 660-666. (Pubitemid 15035598)
9. B.Daniele, A. Bencivenga, A.S.Megna andV. Tinessa, Alphafetoprotein and ultrasonography screening for hepatocellular carcinoma, Gastroenterology 127 (2004), S108-S112. (Pubitemid 39423377)
10. M.A. Comunale, M. Wang, J. Hafner, J. Krakover, L. Rodemich, B. Kopenhaver, R.E. Long, O. Junaidi, A.M. Bisceglie, T.M. Block and A.S. Mehta, Identification and development of fucosylated glycoproteins as biomarkers of primary hepatocellular carcinoma, J Proteome Res 8 (2009), 595-602. (Pubitemid 43224256)
11. V. Paradis, F. Degos, D. Dargere, N. Pham, J. Belghiti, C. Degott, J.L. Janeau, A. Bezeaud, D. Delforge, M. Cubizolles, I. Laurendeau and P. Bedossa, Identification of a new marker of hepatocellular carcinoma by serum protein profiling of patients with chronic liver diseases, Hepatology 41 (2005), 40-47. (Pubitemid 40066381)
12. M.J. Lee, G.R. Yu, S.H. Park, B.H. Cho, J.S. Ahn, H.J. Park, E.Y. Song and D.G. Kim, Identification of cystatin B as a potential serummarker in hepatocellular carcinoma, Clin Cancer Res 14 (2008), 1080-1089. (Pubitemid 351302554)
13. M. Sakamoto, Early HCC: diagnosis and molecular markers, J Gastroenterol 44 Suppl 19 (2009), 108-111.
14. J. Villanueva, D.R. Shaffer, J. Philip, C.A. Chaparro, H. ErdjumentBromage, A.B. Olshen, M. Fleisher, H. Lilja, E. Brogi, J. Boyd, M. SanchezCarbayo, E.C. Holland, C. CordonCardo, H.I. Scher and P. Tempst, Differential exoprotease activities confer tumorspecific serum peptidome patterns, J Clin Invest 116 (2006), 271-284. (Pubitemid 43121812)
15. M.A. Feitelson, J. Pan and Z. Lian, Early molecular and genetic determinants of primary liver malignancy, Surg Clin North Am 84 (2004), 339-354. (Pubitemid 38388271)
16. Z. Sun and P. Yang, Role of imbalance between neutrophil elastase and alpha antitrypsin in cancer development and progression, Lancet Oncol 5 (2004), 182-190. (Pubitemid 38262851)
17. X.D. Zhou, Recurrence and metastasis of hepatocellular carcinoma: progress and prospects, Hepatobiliary Pancreat Dis Int 1 (2002), 35-41. (Pubitemid 36748165)
18. F.R. Rickles, M. Levine and R.L. Edwards, Hemostatic alterations in cancer patients, Cancer Metastasis Rev 11 (1992), 237-248.
19. R. Goldman, H.W. Ressom,M. AbdelHamid, L.Goldman, A. Wang, R.S. Varghese, Y. An, C.A. Loffredo, S.K. Drake, S.A. Eissa, I. Gouda, S. Ezzat and F.S. Moiseiwitsch, Candidate markers for the detection of hepatocellular carcinoma in lowmolecularweight fraction of serum, Carcinogenesis 28 (2007), 2149-2153. (Pubitemid 47543375)
20. E. Orvisky, S.K. Drake, B.M.Martin, M. AbdelHamid, H.W. Ressom, R.S.Varghese, Y.An, D. Saha, G.L.Hortin, C.A. Loffredo and R.Goldman, Enrichment of low molecular weight fraction of serum for mass spectrometric analysis of peptides associated with hepatocellular carcinoma, Proteomics 6 (2006), 2895-2902. (Pubitemid 43752049)
21. H.W. Ressom, R.S. Varghese, L. Goldman, Y. An, C.A. Loffredo, M. AbdelHamid, Z. Kyselova, Y. Mechref, M. Novotny, S.K. Drake and R. Goldman, Analysis of MALDITOF mass spectrometry data for discovery of peptide and glycan biomarkers of hepatocellular carcinoma, J Proteome Res 7 (2008), 603-610. (Pubitemid 351294022)
22. Y. An, H.W. Ressom and R. Goldman, Enrichment of Serum Peptides and Analysis by MALDITOF Mass Spectrometry in The Protein Protocols Handbook, 3rd edition, J.Walker editor, Humana Press (2009), 1167-1174.
23. J. Villanueva, A. Nazarian, K. Lawlor, S.S. Yi, R.J. Robbins and P. Tempst, A sequencespecific exopeptidase activity test (SSEAT) for functional biomarker discovery, Mol Cell Proteomics 7 (2008), 509-518. (Pubitemid 351472461)
24. J.N. Adkins, S.M. Varnum, K.J. Auberry, R.J. Moore, N.H. Angell, R.D. Smith, D.L. Springer and J.G. Pounds, Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry, Mol Cell Proteomics 1 (2002), 947-955.
25. S. Ezzat, M. AbdelHamid, S.A. Eissa, N. Mokhtar, N.A. Labib, L. El Ghorory, N.N. Mikhail, A. AbdelHamid, T. Hifnawy, G.T. Strickland and C.A. Loffredo, Associations of pesticides, HCV,HBV, and hepatocellular carcinoma in Egypt, Int J Hyg Environ Health 208 (2005), 329-339. (Pubitemid 41207425)
26. M.K.Mohamed, Viral Hepatitis C Infection among Egyptians; The Magnitude of the Problem, Epidemiological and Laboratory Approach, Journal of Egyptian Public Health Association 71 (1996), 79-111.
27. H.W. Ressom, R.S. Varghese, S.K. Drake, G.L. Hortin, M. AbdelHamid, C.A. Loffredo and R. Goldman, Peak selection from MALDITOF mass spectra using ant colony optimization, Bioinformatics 23 (2007), 619-626. (Pubitemid 46522596)
28. E.P. Diamandis, Peptidomics for cancer diagnosis: present and future, J Proteome Res 5 (2006), 2079-2082. (Pubitemid 44330798)
29. Y. Ishida, K. Yamashita, H. Sasaki, I. Takajou, Y. Kubuki, K. Morishita, H. Tsubouchi and A. Okayama, Activation of complement system in adult Tcell leukemia (ATL) occurs mainly through lectin pathway: a serum proteomic approach using mass spectrometry, Cancer Lett 271 (2008), 167-177.
30. J.T. Chang, L.C. Chen, S.Y.Wei, Y.J. Chen, H.M.Wang, C.T. Liao, I.H. Chen and A.J. Cheng, Increase diagnostic efficacy by combined use of fingerprintmarkers inmass spectrometry - plasma peptidomes from nasopharyngeal cancer patients for example, Clin Biochem 39 (2006), 1144-1151.
31. M.P. Ebert, D. Niemeyer, S.O. Deininger, T. Wex, C. Knippig, J. Hoffmann, J. Sauer, W. Albrecht, P. Malfertheiner andC. Rocken, Identification and confirmation of increased fibrinopeptide a serum protein levels in gastric cancer sera by magnet bead assisted MALDITOF mass spectrometry, J Proteome Res 5 (2006), 2152-2158. (Pubitemid 44330807)
32. L.F. Steel, D. Shumpert, M. Trotter, S.H. Seeholzer, A.A. Evans,W.T. London, R. Dwek and T.M. Block, A strategy for the comparative analysis of serum proteomes for the discovery of biomarkers for hepatocellular carcinoma, Proteomics 3 (2003), 601-606 (Pubitemid 36570251)
33. L. Miguet, R. Bogumil, P. Decloquement, R. Herbrecht, N. Potier, L. Mauvieux and A. Van Dorsselaer, Discovery and identification of potential biomarkers in a prospective study of chronic lymphoid malignancies using SELDITOFMS, J Proteome Res 5 (2006), 2258-2269. (Pubitemid 44330819)
34. J.M. Koomen, D. Li, L.C. Xiao, T.C. Liu, K.R. Coombes, J. Abbruzzese and R. Kobayashi, Direct tandem mass spectrometry reveals limitations in protein profiling experiments for plasma biomarker discovery, J Proteome Res 4 (2005), 972-981. (Pubitemid 40863287)
35. C.W. Strey, M. Markiewski, D. Mastellos, R. Tudoran, L.A. Spruce, L.E. Greenbaum and J.D. Lambris, The proinflammatorymediators C3a andC5a are essential for liver regeneration, J Exp Med 198 (2003), 913-923. (Pubitemid 37152928)
36. M.M. Markiewski, D. Mastellos, R. Tudoran, R.A. DeAngelis, C.W. Strey, S. Franchini, R.A. Wetsel, A. Erdei and J.D. Lambris, C3a and C3b activation products of the third component of complement (C3) are critical for normal liver recovery after toxic injury, J Immunol 173 (2004), 747-754. (Pubitemid 38924248)
37. P. Gasque, Complement: a unique innate immune sensor for danger signals, Mol Immunol 41 (2004), 1089-1098. (Pubitemid 39345390)
38. C. Kemper and J.P. Atkinson, Tcell regulation: with complements from innate immunity, Nat Rev Immunol 7 (2007), 9-18. (Pubitemid 46020823)
39. A. Sahu and J.D. Lambris, Structure and biology of complement protein C3, a connecting link between innate and acquired immunity, Immunol Rev 180 (2001), 35-48. (Pubitemid 32472850)
40. V.S. Ganu, H.J.MullerEberhard and T.E. Hugli, Factor C3f is a spasmogenic fragment released from C3b by factors I and H: the heptadecapeptide C3f was synthesized and characterized, Mol Immunol 26 (1989), 939-948.
41. J. Marshall, P. Kupchak, W. Zhu, J. Yantha, T. Vrees, S. Furesz, K. Jacks, C. Smith, I. Kireeva, R. Zhang, M. Takahashi, E. Stanton and G. Jackowski, Processing of serum proteins underlies the mass spectral fingerprinting of myocardial infarction, J Proteome Res 2 (2003), 361-372. (Pubitemid 36988415)
42. S.M. Sy, P.B. Lai, E. Pang, N.L. Wong, K.F. To, P.J. Johnson and N. Wong, Novel identification of zyxin upregulations in themotile phenotype of hepatocellular carcinoma, Mod Pathol 19 (2006), 1108-1116. (Pubitemid 44106726)
43. H.R. Bergen, III, G. Vasmatzis, W.A. Cliby, K.L. Johnson, A.L. Oberg and D.C.Muddiman, Discovery of ovarian cancer biomarkers in serum using NanoLC electrospray ionization TOF and FTICR mass spectrometry, Dis Markers 19 (2003), 239-249.
44. D. Theodorescu, S. Wittke, M.M. Ross, M. Walden, M. Conaway, I. Just, H. Mischak and H.F. Frierson, Discovery and validation of new protein biomarkers for urothelial cancer: a prospective analysis, Lancet Oncol 7 (2006), 230-240. (Pubitemid 43286453)
45. M.T. Davis and S.D. Patterson, Does the serum peptidome reveal hemostatic dysregulation? Ernst Schering Res Found Workshop (2007), 23-44.
46. J. Rak, J.L. Yu, J. Luyendyk and N. Mackman, Oncogenes, trousseau syndrome, and cancerrelated changes in the coagulome of mice and humans, Cancer Res 66 (2006), 10643-10646. (Pubitemid 44876956)
47. R. Kaufmann, S. Rahn, K. Pollrich, J. Hertel, Y. Dittmar, M. Hommann, P. Henklein, C. Biskup, M. Westermann, M.D. Hollenberg and U. Settmacher, Thrombinmediated hepatocellular carcinoma cell migration: cooperative action via proteinaseactivated receptors 1 and 4, J Cell Physiol 211 (2007), 699-707. (Pubitemid 46683038)
48. G. Hjortoe, B.B. Sorensen, L.C. Petersen and L.V. Rao, Factor VIIa binding and internalization in hepatocytes, J Thromb Haemost 3 (2005), 2264-2273. (Pubitemid 41727206)
49. P.C.Winter, The pathogenesis of venous thromboembolism in cancer: emerging links with tumour biology, Hematol Oncol 24 (2006), 126-133.
50. G.J. Miller, K.A. Bauer, D.J. Howarth, J.A. Cooper, S.E. Humphries and R.D. Rosenberg, Increased incidence of neoplasia of the digestive tract in men with persistent activation of the coagulant pathway, J Thromb Haemost 2 (2004), 2107-2114.
51. D.E. Baranano, M. Rao, C.D. Ferris and S.H. Snyder, Biliverdin reductase: amajor physiologic cytoprotectant, Proc Natl Acad Sci U S A 99 (2002), 16093-16098. (Pubitemid 35462754)
52. Y. Liu, P. Li, J. Lu,W. Xiong, J. Oger, W. Tetzlaff and M. Cynader, Bilirubin possesses powerful immunomodulatory activity and suppresses experimental autoimmune encephalomyelitis, J Immunol 181 (2008), 1887-1897.
53. M.Niittynen, J.T. Tuomisto, S. Auriola, R. Pohjanvirta, P. Syrjala, U. Simanainen, M. Viluksela and J. Tuomisto, 2,3,7,8tetrachlorodibenzopdioxin (TCDD)induced accumulation of biliverdin and hepatic peliosis in rats, Toxicol Scibf 71 (2003), 112-123. (Pubitemid 36163711)