GW3965, a synthetic liver X receptor (LXR) agonist, reduces angiotensin II-mediated pressor responses in Sprague-Dawley rats

British Journal of Pharmacology

Volumn 151, Issue 4, 2007, Pages 450-456

  Leik, C E ^a   Carson, N L ^a   Hennan, J K ^a   Basso, M D ^a   Liu, Q Y ^a   Crandall, D L ^a   Nambi, P ^a  

^a PFIZER INC   (United States)

Author keywords

Angiotensin II; Angiotensin II receptor; Blood pressure; Liver X receptor

Indexed keywords

3 [3 [[2 CHLORO 3 (TRIFLUOROMETHYL)BENZYL](2 DIPHENYLETHYL)AMINO]PROPOXY]PHENYLACETIC ACID; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; LIVER X RECEPTOR; PENTOBARBITAL; RENIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL BLOOD; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DRUG EFFECT; GENE EXPRESSION; HEART RATE; LIPID METABOLISM; MALE; MEAN ARTERIAL PRESSURE; MESENTERIC ARTERY; NONHUMAN; PLASMA RENIN ACTIVITY; PRESSOR RESPONSE; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

ANGIOTENSIN II; ANIMALS; BENZOIC ACIDS; BENZYLAMINES; BLOOD PRESSURE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; LIPIDS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANGIOTENSIN; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RENIN;

EID: 34250192234     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707241     Document Type: Article

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