Further Insight into Substrate Recognition by USP7: Structural and Biochemical Analysis of the HdmX and Hdm2 Interactions with USP7

Journal of Molecular Biology

Volumn 402, Issue 5, 2010, Pages 825-837

  Sarkari, Feroz ^a   La Delfa, Anthony ^b   Arrowsmith, Cheryl H ^c   Frappier, Lori ^a   Sheng, Yi ^b   Saridakis, Vivian ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b YORK UNIVERSITY   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Hdm2; HdmX; Protein protein interactions; Structural biology; USP7 HAUSP

Indexed keywords

EPSTEIN BARR VIRUS ANTIGEN 1; PROTEIN HDMX; PROTEIN MDM2; PROTEIN P53; PROTEIN USP7; PROTEINASE; SERINE; UNCLASSIFIED DRUG; MDM2 PROTEIN, HUMAN; MDM4 PROTEIN, HUMAN; NUCLEAR PROTEIN; ONCOPROTEIN; PROTEIN BINDING; UBIQUITIN THIOLESTERASE; USP7 PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN METABOLISM; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; PROTEIN ANALYSIS; PROTEIN QUATERNARY STRUCTURE; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, QUATERNARY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; SEQUENCE ALIGNMENT; SERINE; UBIQUITIN THIOLESTERASE;

EID: 77957220495     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.08.017     Document Type: Article

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