Aurora kinase A in Barrett's carcinogenesis

Human Pathology

Volumn 41, Issue 10, 2010, Pages 1380-1386

  Rugge, Massimo ^a,b   Fassan, Matteo ^a   Zaninotto, Giovanni ^a   Pizzi, Marco ^a   Giacomelli, Luciano ^c   Battaglia, Giorgio ^b   Rizzetto, Christian ^b   Parente, Paola ^b   Ancona, Ermanno ^a,b  

^a UNIVERSITY OF PADOVA   (Italy)

^b VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

^c UNIVERSITY HOSPITAL OF PADOVA   (Italy)

Author keywords

AURKA; Barrett's esophagus; Esophageal cancer; Immunohistochemistry; Micronuclei; TP53

Indexed keywords

AURORA A KINASE; PROTEIN P53; AURKA PROTEIN, HUMAN; AURORA KINASE; PROTEIN SERINE THREONINE KINASE; TP53 PROTEIN, HUMAN;

ARTICLE; BARRETT ESOPHAGUS; CANCER GRADING; CARCINOGENESIS; CHROMOSOMAL INSTABILITY; CONTROLLED STUDY; ESOPHAGUS BIOPSY; ESOPHAGUS CARCINOMA; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE METAPLASIA; MAJOR CLINICAL STUDY; PHENOTYPE; ADENOCARCINOMA; BIOSYNTHESIS; CARCINOMA IN SITU; CELL TRANSFORMATION; DNA MICROARRAY; ENZYMOLOGY; ESOPHAGUS; ESOPHAGUS TUMOR; INTESTINE MUCOSA; METABOLISM; METAPLASIA; MUCOSA; NUCLEAR SIZE; PATHOLOGY; RETROSPECTIVE STUDY; STOMACH MUCOSA;

ADENOCARCINOMA; BARRETT ESOPHAGUS; CARCINOMA IN SITU; CELL NUCLEUS SIZE; CELL TRANSFORMATION, NEOPLASTIC; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; GASTRIC MUCOSA; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; METAPLASIA; MUCOUS MEMBRANE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN-SERINE-THREONINE KINASES; RETROSPECTIVE STUDIES; TUMOR SUPPRESSOR PROTEIN P53; AURORA KINASE A; AURORA KINASES;

EID: 77957159658     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2010.02.016     Document Type: Article

References (34)

1. Jankowski J.A, Wright N.A, and Meltzer S.J. Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagus Am J Pathol 154 1999 965 973
2. Jankowski J.A, Harrison R.F, Perry I, Balkwill F, and Tselepis C. Barrett's metaplasia Lancet 356 2000 2079 2085
3. Sampliner R.E. Updated guidelines for the diagnosis, surveillance, and therapy of Barrett's esophagus Am J Gastroenterol 97 2002 1888 1895
4. Enzinger P.C, and Mayer R.J. Esophageal cancer N Engl J Med 349 2003 2241 2252
5. Paulson T.G, and Reid B.J. Focus on Barrett's esophagus and esophageal adenocarcinoma Cancer Cell 6 2004 11 16
6. Fitzgerald R.C. Molecular basis of Barrett's oesophagus and oesophageal adenocarcinoma Gut 55 2006 1810 1820
7. Zaninotto G, Parenti A.R, Ruol A, Costantini M, Merigliano S, and Ancona E. Oesophageal resection for high-grade dysplasia in Barrett's oesophagus Br J Surg 87 2000 1102 1105
8. Conio M, Blanchi S, and Lapertosa G. Long-term endoscopic surveillance of patients with Barrett's esophagus. Incidence of dysplasia and adenocarcinoma: a prospective study Am J Gastroenterol 98 2003 1931 1939
9. Marumoto T, Zhang D, and Saya H. Aurora A-a guardian of poles Nat Rev Cancer 5 2005 42 50
10. Lapenna S, and Giordano A. Cell cycle kinases as therapeutic targets for cancer Nat Rev Drug Disc 8 2009 547 566
11. Gautschi O, Heighway J, Mack P.C, Purnell P.R, Lara P.N, and Gandara D.R. Aurora kinases as anticancer drug targets Clin Cancer Res 14 2008 1639 1648
12. Zhou H, Kuang J, and Zhong L. Tumor amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation Nat Genet 20 1998 189 193
13. Dutrertre S, Descamps S, and Pringent C. On the role of aurora-A in centrosome function Oncogene 21 2002 6175 6183
14. Agnese V, Cabibi D, and Calcara D. Aurora-A overexpression as an early marker of reflux-related columnar mucosa and Barrett's oesophagus Ann Surg 18 Suppl 6 2007 vi110 vi115
15. Dar A.A, Zaika A, and Piazuelo M.B. Frequent overexpression of Aurora kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions Cancer 112 2008 1688 1698
16. Rhodes D.R, Yu J, and Shanker K. ONCOMINE: a cancer microarray database and integrated data-mining platform Neoplasia 6 2004 1 6
17. Rhodes D.R, Yu J, and Shanker K. Large-scale metaanalysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression Proc Natl Acad Sci U S A 101 2004 9309 9314
18. Xin W, Rhodes D.R, Ingold C, Chinnaivan A.M, and Rubin M.A. Dysregulation of the annexin family protein family is associated with prostate cancer progression Am J Pathol 162 2003 255 261
19. Zaninotto G, Minnei F, and Guirroli E. The Veneto region's Barrett's Oesophagus Registry: aims, methods, preliminary results Dig Liver Dis 39 2007 18 25
20. Werner M, Flejou J.F, Hainaut P, Höfler H, Lambert R, Keller G. , and Stein H.J. Adenocarcinoma of the oesophagus S.R. Hamilton, L.A. Aaltonen, World Health Organisation classification of tumours. Pathology & genetics. Tumours of the digestive system 2000 IARC Press Lyon, France 20 26
21. Rugge M, Fassan M, and Clemente R. Bronchopulmonary carcinoid: phenotype and long-term outcome in a single-institution series of Italian patients Clin Cancer Res 14 2008 149 154
22. Sen S, Zhou H, and Zhang R.D. Amplification/overexpression of a mitotic kinase gene in human bladder cancer J Natl Cancer Inst 94 2002 1320 1329
23. Guido M, Fassan M, and Giacomelli L. Micronuclei and broken eggs in human liver carcinogenesis Anticancer Res 28 2008 2507 2511
24. Landis J.R, and Koch G.G. The measurement of observer agreement for categorical data Biometrics 33 1977 159 171
25. Kimchi E.T, Posner M.C, and Park J.O. Progression of Barrett's metaplasia to adenocarcinoma is associated with the suppression of the transcriptional programs of epidermal differentation Cancer Res 65 2005 3146 3154
26. Hao Y, Triadafilopoulos G, Sahbaie P, Young H.S, Omary M.B, and Lowe A.W. Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma Gastroenterology 131 2006 925 933
27. Vakil N, van Zanten S.V, Kahrilas P, Dent J, Jones R. Global Consensus Group The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus Am J Gastroenterol 101 2006 1900 1920
28. Rugge M, Fassan M, Battaglia G, Parente P, Zaninotto G, and Ancona E. Intestinal or gastric? The unsolved dilemma of Barrett's metaplasia Hum Pathol 40 2009 1206 1207
29. Katayama H, Sasai K, and Kawai H. Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53 Nat Genet 36 2004 55 62
30. Liu Q, Kaneko S, and Yang L. Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215 J Biol Chem 279 2004 52175 52182
31. Kerkhof M, Steyerberg E.W, and Kusters J.G. Aneuploidy and high expression of p53 and Ki67 is associated with neoplastic progression in Barrett's esophagus Cancer Biomark 4 2008 1 10
32. Sikkema M, Kerkhof M, and Steyerberg E.W. Aneuploidy and overexpression of Ki67 and p53 as markers for neoplastic progression in Barrett's esophagus: a case-control study Am J Gastroenterol 104 2009 2673 2680
33. Holland A.J, and Cleveland D.W. Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis Nat Rev Cell Biol 10 2009 478 487
34. Reid B.J, Blount P.L, Rubin C.E, Levine D.S, Haggitt R.C, and Rabinovitch P.S. Flow-cytometric and histological progression to malignancy in Barrett's esophagus: prospective endoscopic surveillance of a cohort Gastroenterology 102 1992 1212 1219