Carboxymethyl chitin-glucan (CM-CG) protects human HepG2 and HeLa cells against oxidative DNA lesions and stimulates DNA repair of lesions induced by alkylating agents

Toxicology in Vitro

Volumn 24, Issue 7, 2010, Pages 1986-1992

  Slameňová, Darina ^a   Kováčiková, Ines ^a   Horváthová, Eva ^a   Wsólová, Ladislava ^b   Navarová, Jana ^c  

^a CANCER RESEARCH INSTITUTE   (Slovakia)

^b Research Base of the Slovak Medical University   (Slovakia)

^c INSTITUTE OF EXPERIMENTAL PHARMACOLOGY AND TOXICOLOGY   (Slovakia)

Author keywords

Carboxymethyl chitin glucan (CM CG); Comet assay; DPPH assay; Methylmethane sulfonate (MMS); N methyl N nitro N nitrosoquanidine (MNNG)

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ALKYLATING AGENT; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CARBOXYMETHYLCHITIN GLUCAN; HYDROGEN PEROXIDE; METHYLMETHANE SULFONIC ACID; METHYLNITRONITROSOGUANIDINE; SINGLE STRANDED DNA; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; ASPERGILLUS NIGER; CANCER CELL; CELL PROTECTION; CELL STRAIN HEPG2; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA REPAIR; DRUG DETERMINATION; DRUG ISOLATION; DRUG MECHANISM; HELA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; OXIDATIVE STRESS; SINGLE STRANDED DNA BREAK;

ALKYLATING AGENTS; ANTIOXIDANTS; ASPERGILLUS NIGER; CHITIN; COMET ASSAY; DNA BREAKS, SINGLE-STRANDED; DNA DAMAGE; DNA REPAIR; GLUCANS; HELA CELLS; HEP G2 CELLS; HUMANS; HYDROGEN PEROXIDE; METHYL METHANESULFONATE; METHYLNITRONITROSOGUANIDINE; OXIDATIVE STRESS;

ASPERGILLUS NIGER;

EID: 77957154318     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.08.015     Document Type: Article

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