-
1
-
-
0037456369
-
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA
-
Aas P.A., Otterlei M., Falnes P.O., Vagbo C.B., Skorpen F., Akbari M., Sundheim O., Bjoras M., Slupphaug G., Seeberg E., and Krokan H.E. Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA. Nature 421 (2002) 859-863
-
(2002)
Nature
, vol.421
, pp. 859-863
-
-
Aas, P.A.1
Otterlei, M.2
Falnes, P.O.3
Vagbo, C.B.4
Skorpen, F.5
Akbari, M.6
Sundheim, O.7
Bjoras, M.8
Slupphaug, G.9
Seeberg, E.10
Krokan, H.E.11
-
2
-
-
0037068446
-
Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage
-
Trewick S.C., Henshaw T.F., Hausinger R.P., Lindahl T., and Sedgwick B. Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage. Nature 419 (2002) 174-178
-
(2002)
Nature
, vol.419
, pp. 174-178
-
-
Trewick, S.C.1
Henshaw, T.F.2
Hausinger, R.P.3
Lindahl, T.4
Sedgwick, B.5
-
4
-
-
0002432057
-
-
Searle C.E. (Ed)
-
Miller E.C., and Miller J.A. In: Searle C.E. (Ed). The metabolism of chemical carcinogens to reactive electrophiles and their possible mechanisms of action in carcinogenesis in chemical carcinogens. ACS Monogr. 173 (1996) 737-762
-
(1996)
ACS Monogr.
, vol.173
, pp. 737-762
-
-
Miller, E.C.1
Miller, J.A.2
-
5
-
-
0000785768
-
Carcinogenesis by alkylating agents
-
Searle C.E. (Ed), American Chemical Society, Washington, DC
-
Lawley P.D. Carcinogenesis by alkylating agents. In: Searle C.E. (Ed). Chemical Carcinogens (1984), American Chemical Society, Washington, DC 83-244
-
(1984)
Chemical Carcinogens
, pp. 83-244
-
-
Lawley, P.D.1
-
6
-
-
0000130061
-
The reaction of mustard gas with nucleic acids in vitro and in vivo
-
Brookes P., and Lawley P.D. The reaction of mustard gas with nucleic acids in vitro and in vivo. Biochem. J. 77 (1960) 478-484
-
(1960)
Biochem. J.
, vol.77
, pp. 478-484
-
-
Brookes, P.1
Lawley, P.D.2
-
7
-
-
0024806379
-
The experimental basis for the role of nitroso compounds in human cancer
-
Magee P.N. The experimental basis for the role of nitroso compounds in human cancer. Cancer Surv. 8 (1989) 207-239
-
(1989)
Cancer Surv.
, vol.8
, pp. 207-239
-
-
Magee, P.N.1
-
9
-
-
0014672640
-
6-alkylation of deoxyguanosine to the mutagenicity and carcinogenicity of nitrosamines and nitrosamides
-
6-alkylation of deoxyguanosine to the mutagenicity and carcinogenicity of nitrosamines and nitrosamides. Nature 223 (1969) 206-207
-
(1969)
Nature
, vol.223
, pp. 206-207
-
-
Loveless, A.1
-
10
-
-
0016042235
-
6-ethylguanine in rat-brain DNA: correlation with nervous system-specific carcinogenesis by ethylnitrosourea
-
6-ethylguanine in rat-brain DNA: correlation with nervous system-specific carcinogenesis by ethylnitrosourea. Proc. Natl. Acad. Sci. U.S.A. 71 (1974) 639-643
-
(1974)
Proc. Natl. Acad. Sci. U.S.A.
, vol.71
, pp. 639-643
-
-
Goth, R.1
Rajewsky, M.F.2
-
13
-
-
0019226227
-
6-methylguanine in a synthetic DNA polymer by an inducible activity in Escherichia coli
-
6-methylguanine in a synthetic DNA polymer by an inducible activity in Escherichia coli. Biochem. Biophys. Res. Commun. 97 (1980) 654-659
-
(1980)
Biochem. Biophys. Res. Commun.
, vol.97
, pp. 654-659
-
-
Foote, R.S.1
Mitra, S.2
Pal, B.C.3
-
16
-
-
0021275369
-
6-methylguanine in template DNA during in vitro DNA replication
-
6-methylguanine in template DNA during in vitro DNA replication. J. Biol. Chem. 259 (1984) 8095-8100
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 8095-8100
-
-
Snow, E.T.1
Foote, R.S.2
Mitra, S.3
-
17
-
-
0021760645
-
6-methyldeoxyguanosine monophosphate during in vitro DNA synthesis
-
6-methyldeoxyguanosine monophosphate during in vitro DNA synthesis. Biochemistry 23 (1984) 4289-4294
-
(1984)
Biochemistry
, vol.23
, pp. 4289-4294
-
-
Snow, E.T.1
Foote, R.S.2
Mitra, S.3
-
21
-
-
0017395439
-
A new pathway for DNA repair in Escherichia coli
-
Samson L., and Cairns J. A new pathway for DNA repair in Escherichia coli. Nature 267 (1977) 281-283
-
(1977)
Nature
, vol.267
, pp. 281-283
-
-
Samson, L.1
Cairns, J.2
-
22
-
-
0004228157
-
-
ASM Press
-
Friederg E.C., Walker G.C., Siede W., Wood R.D., Schultz R.A., and Ellenberger T. DNA Repair and Mutagenesis. second ed. (2005), ASM Press
-
(2005)
DNA Repair and Mutagenesis. second ed.
-
-
Friederg, E.C.1
Walker, G.C.2
Siede, W.3
Wood, R.D.4
Schultz, R.A.5
Ellenberger, T.6
-
24
-
-
0023853497
-
Adaptive response of Escherichia coli to alkylation damage
-
Volkert M.R. Adaptive response of Escherichia coli to alkylation damage. Environ. Mol. Mutagen. 11 (1988) 241-255
-
(1988)
Environ. Mol. Mutagen.
, vol.11
, pp. 241-255
-
-
Volkert, M.R.1
-
25
-
-
0023784535
-
Expression of the ada gene of Escherichia coli in response to alkylating agents. Identification of transcriptional regulatory elements
-
Nakamura T., Tokumoto Y., Sakumi K., Koike G., Nakabeppu Y., and Sekiguchi M. Expression of the ada gene of Escherichia coli in response to alkylating agents. Identification of transcriptional regulatory elements. J. Mol. Biol. 202 (1988) 483-494
-
(1988)
J. Mol. Biol.
, vol.202
, pp. 483-494
-
-
Nakamura, T.1
Tokumoto, Y.2
Sakumi, K.3
Koike, G.4
Nakabeppu, Y.5
Sekiguchi, M.6
-
26
-
-
0024507831
-
Regulation of expression of the ada gene controlling the adaptive response. Interactions with the ada promoter of the Ada protein and RNA polymerase
-
Sakumi K., and Sekiguchi M. Regulation of expression of the ada gene controlling the adaptive response. Interactions with the ada promoter of the Ada protein and RNA polymerase. J. Mol. Biol. 205 (1989) 373-385
-
(1989)
J. Mol. Biol.
, vol.205
, pp. 373-385
-
-
Sakumi, K.1
Sekiguchi, M.2
-
27
-
-
0026048774
-
A region of the Ada DNA-repair protein required for the activation of ada transcription is not necessary for activation of alkA
-
Shevell D.E., and Walker G.C. A region of the Ada DNA-repair protein required for the activation of ada transcription is not necessary for activation of alkA. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 9001-9005
-
(1991)
Proc. Natl. Acad. Sci. U.S.A.
, vol.88
, pp. 9001-9005
-
-
Shevell, D.E.1
Walker, G.C.2
-
29
-
-
33644905598
-
The AidB component of the Escherichia coli adaptive response to alkylating agents is a flavin-containing, DNA-binding protein
-
Rohankhedkar M.S., Mulrooney S.B., Wedemeyer W.J., and Hausinger R.P. The AidB component of the Escherichia coli adaptive response to alkylating agents is a flavin-containing, DNA-binding protein. J. Bacteriol. 188 (2006) 223-230
-
(2006)
J. Bacteriol.
, vol.188
, pp. 223-230
-
-
Rohankhedkar, M.S.1
Mulrooney, S.B.2
Wedemeyer, W.J.3
Hausinger, R.P.4
-
30
-
-
0019211791
-
6-methylguanine to a protein cysteine residue
-
6-methylguanine to a protein cysteine residue. J. Biol. Chem. 255 (1980) 10569-10571
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 10569-10571
-
-
Olsson, M.1
Lindahl, T.2
-
31
-
-
0000742057
-
Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis
-
Demple B., Sedgwick B., Robins P., Totty N., Waterfield M.D., and Lindahl T. Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis. Proc. Natl. Acad. Sci. U.S.A. 82 (1985) 2688-2692
-
(1985)
Proc. Natl. Acad. Sci. U.S.A.
, vol.82
, pp. 2688-2692
-
-
Demple, B.1
Sedgwick, B.2
Robins, P.3
Totty, N.4
Waterfield, M.D.5
Lindahl, T.6
-
35
-
-
0020341190
-
Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-l-methionine is a potentially mutagenic reaction
-
Rydberg B., and Lindahl T. Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-l-methionine is a potentially mutagenic reaction. EMBO J. 1 (1982) 211-216
-
(1982)
EMBO J.
, vol.1
, pp. 211-216
-
-
Rydberg, B.1
Lindahl, T.2
-
36
-
-
0020335344
-
6-methylguanine-DNA methyltransferase in wild-type and ada mutants of Escherichia coli
-
6-methylguanine-DNA methyltransferase in wild-type and ada mutants of Escherichia coli. J. Bacteriol. 152 (1982) 534-537
-
(1982)
J. Bacteriol.
, vol.152
, pp. 534-537
-
-
Mitra, S.1
Pal, B.C.2
Foote, R.S.3
-
38
-
-
0020665434
-
Adaptive response of Bacillus subtilis to N-methyl-N′-nitro-N-nitrosoguanidine
-
Hadden C.T., Foote R.S., and Mitra S. Adaptive response of Bacillus subtilis to N-methyl-N′-nitro-N-nitrosoguanidine. J. Bacteriol. 153 (1983) 756-762
-
(1983)
J. Bacteriol.
, vol.153
, pp. 756-762
-
-
Hadden, C.T.1
Foote, R.S.2
Mitra, S.3
-
44
-
-
0019395086
-
6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines
-
6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines. Nature 289 (1981) 417-420
-
(1981)
Nature
, vol.289
, pp. 417-420
-
-
R. Sklar, R.1
Strauss, B.2
-
45
-
-
0019202685
-
Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains
-
Day III R.S., Ziolkowski C.H., Scudiero D.A., Meyer S.A., Lubiniecki A.S., Girardi A.J., Galloway S.M., and Bynum G.D. Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains. Nature 288 (1980) 724-727
-
(1980)
Nature
, vol.288
, pp. 724-727
-
-
Day III, R.S.1
Ziolkowski, C.H.2
Scudiero, D.A.3
Meyer, S.A.4
Lubiniecki, A.S.5
Girardi, A.J.6
Galloway, S.M.7
Bynum, G.D.8
-
47
-
-
0027351670
-
Regulation of repair of alkylation damage in mammalian genomes
-
Mitra S., and Kaina B. Regulation of repair of alkylation damage in mammalian genomes. Prog. Nucl. Acids Res. Mol. Biol. 44 (1993) 109-141
-
(1993)
Prog. Nucl. Acids Res. Mol. Biol.
, vol.44
, pp. 109-141
-
-
Mitra, S.1
Kaina, B.2
-
48
-
-
0034667383
-
6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent
-
6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent. Cancer Res. 60 (2000) 5815-5824
-
(2000)
Cancer Res.
, vol.60
, pp. 5815-5824
-
-
Ochs, K.1
Kaina, B.2
-
49
-
-
1842715589
-
Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine
-
Hickman M.J., and Samson L.D. Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine. Mol. Cell 14 (2004) 105-116
-
(2004)
Mol. Cell
, vol.14
, pp. 105-116
-
-
Hickman, M.J.1
Samson, L.D.2
-
50
-
-
0025941670
-
6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents
-
6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents. Carcinogenesis 12 (1991) 1857-1867
-
(1991)
Carcinogenesis
, vol.12
, pp. 1857-1867
-
-
Kaina, B.1
Fritz, G.2
Mitra, S.3
Coquerelle, T.4
-
51
-
-
0025116511
-
DNA alkylation by the haloethylnitrosoureas: nature of modifications produced and their enzymatic repair or removal
-
Ludlum D.B. DNA alkylation by the haloethylnitrosoureas: nature of modifications produced and their enzymatic repair or removal. Mutat. Res. 233 (1990) 117-126
-
(1990)
Mutat. Res.
, vol.233
, pp. 117-126
-
-
Ludlum, D.B.1
-
52
-
-
0022064910
-
6-alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chlorethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea
-
6-alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chlorethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea. Proc. Natl. Acad. Sci. U.S.A. 82 (1985) 2985-2989
-
(1985)
Proc. Natl. Acad. Sci. U.S.A.
, vol.82
, pp. 2985-2989
-
-
Brent, T.P.1
Houghton, J.A.2
Houghton, P.J.3
-
53
-
-
0030457071
-
Genomic instability and tolerance to alkylating agents
-
Karran P., and Hampson R.R. Genomic instability and tolerance to alkylating agents. Cancer Surv. 28 (1996) 69-85
-
(1996)
Cancer Surv.
, vol.28
, pp. 69-85
-
-
Karran, P.1
Hampson, R.R.2
-
54
-
-
33747884339
-
DNA damage-induced cell death by apoptosis
-
Roos W.P., and Kaina B. DNA damage-induced cell death by apoptosis. Trends Mol. Med. 12 (2006) 440-450
-
(2006)
Trends Mol. Med.
, vol.12
, pp. 440-450
-
-
Roos, W.P.1
Kaina, B.2
-
55
-
-
0037310904
-
6-alkylguanine-DNA alkyltransferase and mismatch repair activities on the sensitivity of human melanoma cells to temozolomide 1,3-bis(2-chloroethyl)1-nitrosourea, and cisplatin
-
6-alkylguanine-DNA alkyltransferase and mismatch repair activities on the sensitivity of human melanoma cells to temozolomide 1,3-bis(2-chloroethyl)1-nitrosourea, and cisplatin. J. Pharmacol. Exp. Ther. 304 (2003) 661-668
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.304
, pp. 661-668
-
-
Pepponi, R.1
Marra, G.2
Fuggetta, M.P.3
Falcinelli, S.4
Pagani, E.5
Bonmassar, E.6
Jiricny, J.7
D'Atri, S.8
-
56
-
-
4444351655
-
Dual repair modulation reverses Temozolomide resistance in vitro
-
Barvaux V.A., Ranson M., Brown R., McElhinney R.S., McMurry T.B., and Margison G.P. Dual repair modulation reverses Temozolomide resistance in vitro. Mol. Cancer Ther. 3 (2004) 123-127
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 123-127
-
-
Barvaux, V.A.1
Ranson, M.2
Brown, R.3
McElhinney, R.S.4
McMurry, T.B.5
Margison, G.P.6
-
57
-
-
0025767132
-
6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments
-
6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments. Mol. Cell. Biol. 11 (1991) 4660-4668
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 4660-4668
-
-
Fritz, G.1
Tano, K.2
Mitra, S.3
Kaina, B.4
-
59
-
-
0033552810
-
6-methylguanine-DNA methyltransferase gene by glucocorticoid hormone
-
6-methylguanine-DNA methyltransferase gene by glucocorticoid hormone. Oncogene 18 (1999) 525-532
-
(1999)
Oncogene
, vol.18
, pp. 525-532
-
-
Biswas, T.1
Ramana, C.V.2
Srinivasan, G.3
Boldogh, I.4
Hazra, T.K.5
Chen, Z.6
Tano, K.7
Thompson, E.B.8
Mitra, S.9
-
60
-
-
0032170560
-
6-methylguanine-DNA methyltransferase via protein kinase C-mediated signaling
-
6-methylguanine-DNA methyltransferase via protein kinase C-mediated signaling. Cancer Res. 58 (1998) 3950-3956
-
(1998)
Cancer Res.
, vol.58
, pp. 3950-3956
-
-
Boldogh, I.1
Ramana, C.V.2
Chen, Z.3
Biswas, T.4
Hazra, T.K.5
Grosch, S.6
Grombacher, T.7
Mitra, S.8
Kaina, B.9
-
61
-
-
0034602378
-
6-methylguanine-DNA methyltransferase gene by transcriptional coactivators cAMP response element-binding protein-binding protein and p300
-
6-methylguanine-DNA methyltransferase gene by transcriptional coactivators cAMP response element-binding protein-binding protein and p300. J. Biol. Chem. 275 (2000) 34197-34204
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34197-34204
-
-
Bhakat, K.K.1
Mitra, S.2
-
63
-
-
0030002739
-
Organization and expression of the mouse gene for DNA repair methyltransferase
-
Iwakuma T., Shiraishi A., Fukuhara M., Kawate H., and Sekiguchi M. Organization and expression of the mouse gene for DNA repair methyltransferase. DNA Cell Biol. 15 (1996) 863-872
-
(1996)
DNA Cell Biol.
, vol.15
, pp. 863-872
-
-
Iwakuma, T.1
Shiraishi, A.2
Fukuhara, M.3
Kawate, H.4
Sekiguchi, M.5
-
64
-
-
0042889258
-
6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration
-
6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration. Carcinogenesis 24 (2003) 1337-1345
-
(2003)
Carcinogenesis
, vol.24
, pp. 1337-1345
-
-
Bhakat, K.K.1
Mitra, S.2
-
66
-
-
0025299609
-
6-methylguanine-DNA methyltransferase. cDNA expression in Escherichia coli and gene expression in human cells
-
6-methylguanine-DNA methyltransferase. cDNA expression in Escherichia coli and gene expression in human cells. J. Biol. Chem. 265 (1990) 9563-9569
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 9563-9569
-
-
Rydberg, B.1
Spurr, N.2
Karran, P.3
-
68
-
-
0025949662
-
Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase
-
Chakravarti D., Ibeanu G.C., Tano K., and Mitra S. Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase. J. Biol. Chem. 266 (1991) 15710-15715
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 15710-15715
-
-
Chakravarti, D.1
Ibeanu, G.C.2
Tano, K.3
Mitra, S.4
-
69
-
-
0025196019
-
6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents
-
6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 5368-5372
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 5368-5372
-
-
Dolan, M.E.1
Moschel, R.C.2
Pegg, A.E.3
|