Growth and lactogenic hormones, insulin-like growth factor and insulin

NeuroImmune Biology

Volumn 3, Issue C, 2003, Pages 129-153

  Berczi, Istvan ^a,b   Szentivanyi, Andor ^a,b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77957148783     PISSN: 15677443     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1567-7443(03)80045-5     Document Type: Article

References (173)

1. Nicoll C.S. Prolactin and growth hormone: specialists on one hand and mutual mimics on the other. Perspect Biol Med 25 (1982) 1369-1381
2. Nickel B.E., Kardami E., and Cattini P.A. The human placental growth hormone variant is mitogenic for rat lymphoma Nb2 cells. Endocrinology 126 (1990) 971-976
3. Southard J.N., and Talamantes F. Placental prolactin-like proteins in rodents-variations on a structural theme. Mol Cell Endocrinol 79 (1991) C133-C140
4. Berczi I. The immunology of prolactin. Sem Reprod Endocrinol 10 (1992) 196-219
5. Lewis U.J. Growth hormone-what is it and what does it do. Trends Endocrinol Metab 3 (1992) 117-121
6. Duckworth M.L., Robertson M.C., Schroedter M.L., et al. Molecular genetics and biology of the rat placental prolactin family. In: Soares M.J., Handwerger S., and Talamantes F. (Eds). Trophoblast Cells: Pathways for Maternal-Embryonic Communication (1993), Springer, New York 169-190
7. Freeman M.E., Kanyicska B., Lerant A., and Nagy G. Prolactin: structure, function, and regulation of secretion. Physiol Rev 80 (2000) 1523-1631
8. Aaronson S.A. Growth factors and cancer. Science 254 (1991) 1146-1153
9. Kishimoto T., Taga T., and Akira S. Cytokine signal transduction. Cell 76 (1994) 253-262
10. Touraine P., Leite de Moraes M.C., Dardenne M., and Kelly P.A. Expression of short and long forms of prolactin receptor in murine lymphoid tissues. Mol Cell Endocrinol 104 (1994) 183-190
11. Koh C.Y., and Phillips J.T. Prolactin receptor expression by lymphoid tissues in normal and immunized rats. Mol Cell Endocrinol 92 (1993) R21-R25
12. Gagnerault M.C., Touraine P., and Savino W. Expression of prolactin receptors in murine lymphoid cells in normal and autoimmune situations. J Immunol 150 (1993) 5673-5681
13. Corbacho A.M., Nava G., Eiserich J.P., Noris G., Macotela Y., Struman I., Martinez De La Dardenne M., Mello-Coelho V., Gagnerault M.C., and Postel-Vinay M.C. Growth hormone receptors and immunocompetent cells. Ann N Y Acad Sci 840 (1998) 510-517
14. Chen H.T., Schuler L.A., and Schultz R.D. Growth hormone receptor and regulation of gene expression in fetal lymphoid cells. Mol Cell Endocrinol 137 (1998) 21-29
15. Thellin O., Coumans B., Zorzi W., Barnard R., Hennen G., Heinen E., and Igout A. Expression of growth hormone receptors by lymphocyte subpopulations in the human tonsil. Dev Immunol 6 (1998) 295-304
16. Valerio G., Bond H.M., Badolato R., Petrella A., Di Maio S., Salcrno M., Waters M.J., Venuta S., and Tenore A. Expression of growth hormone receptor by peripheral blood lymphocytes in children: evaluation in clinical conditions of impaired growth. Clin Endocrinol (Oxf) 47 (1997) 329-335
17. Cohick W.S., and Clemmons D.R. The insulin-like growth factors. Annu Rev Physiol 55 (1993) 131-153
18. Nicoll C.S., Hebert N.J., Delidow B.C., English D.E., and Russell S.M. Prolactin and synlactin: comparative aspects. Prog Clin Biol Res 342 (1990) 211-218
19. Wells J.A., and de Vos A.M. Structure and function of human growth hormone: implications for the hematopoietins. Annu Rev. Biophys. Biomol. Struct 115 (1993) 46-52
20. Kelly P.A., Djiane J., Postel-Vinay M.C., and Edery M. The prolactin/growth hormone receptor family. Endocrine Rev 12 (1991) 235-251
21. Rui H., Lebrun J.J., and Kirken R.A. JAK2 activation and cell proliferation induced by antibodymediated prolactin receptor dimerization. Endocrinology 135 (1994) 1299-1306
22. Clevenger C.V., Sillman A.L., and Prytowsky M.B. Interleukin-2 dirven nuclear translocation of prolactin in cloned T-lymphocytes. Endocrinology 127 (1990) 3151-3159
23. Clevenger C.V., Freier D.O., and Kline J.B. Prolactin receptor signal transduction in cells of the immune system. J Endocrinol 157 (1998) 187-197
24. Rao Y.P., Olson M.D., Buckley D.J., and Buckley A. Nuclear co-localization of prolactin and the prolactin receptor in rat Nb2 node lymphoma cells. Endocrinology 133 (1990) 3062-3065
25. Lobie P.E., Mertani H., and Morel G. Receptor-mediated nuclear translocation of growth hormone. J Biol Chem 269 (1994) 21330-21339
26. Belkowski S.M., Levine J.E., and Prystowsky M.B. Requirement of PI3-kinase activity for the nuclear transport of prolactin in cloned murine T lymphocytes. J Neuroimmun 94 (1999) 40-47
27. Horseman N.D., and Yu-Lee L.Y. Transcriptional regulation by the helix bundle peptide hormones: growth hormone, prolactin and hematopoietic cytokines. Endocrine Rev 15 (1994) 627-649
28. Bole-Feysot C., Goffin V., Edery M., Binart N., and Kelly P.A. Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr Rev 19 (1998) 225-268
29. Akira S. Functional roles of STAT family proteins: lessons from knockout mice. Stem Cells 17 (1999) 138-146
30. Davey H.W., Wilkins R.J., and Waxman D.J. STAT5 signaling in sexually dimorphic gene expression and growth patterns. Am J Hum Genet 65 (1999) 959-965
31. Weigent D.A., Vines C.R., Long J.C., Blalock J.E., and Elton T.S. Characterization of the promoterdirecting expression of growth hormone in a monocyte cell line. Neuroimmunomodulation 7 (2000) 126-134
32. Port C.B., Bowen J.M., Keyes P.L., and Townson D.H. Effects of a 3beta-hydroxysteroid dehydrogenase inhibitor on monocyte-macrophage infiltration into rat corpus luteum and on apoptosis: relationship to the luteolytic action of prolactin. J Repord Fertil 119 (2000) 93-99
33. rd Edition (1975), Year Book, Chicago
34. Nagy E., Berczi I., and Friesen H.G. Regulation of immunity in rats by lactogenic and growth hormones. Acta Endocrinol 102 (1983) 351-357
35. Berczi I., and Nagy E. Human placental lactogen is a hemopoeitic hormone. Brit J Haematol 79 (1991) 355-358
36. Moreno J., Vicente A., Heijnen I., and Zapata A.G. Prolactin and early T-cell development in embryonic chicken. Immunol Today 15 (1994) 524-526
37. Crilly P.R., Johnson P.C., Gardner M.J., and Flint D.J. Immunoneutralisation of GH in neonatal rats results in defects in lymphatic tissues and the humoral immune response. Endocrine J 2 (1994) 105-107
38. Ellis L.A., Mastro A.M., and Picciano M.F. Milk-borne prolactin and neonatal development. J Mammary Gland Biol Neoplasia 1 (1996) 259-269
39. Crafts R.C., and Meinecke H.A. The anemia of hypophysectomized animals. Ann NY Acad Sci 77 (1959) 501-517
40. Jepson J.H., and Lowenstein L. The effect of testosterone, adrenal steroids and prolactin on erythropoiesis. Acta Haematol 38 (1967) 292-299
41. Berczi I., and Nagy E. The effect of prolactin and growth hormone on hemolyphopoietic tissue and immune function. In: Berczi I., and Kovac K. (Eds). Hormones and Immunity (1987), MTP Press, Lancaster, England 145-171
42. Nagy E., and Berczi I. Pituitary dependence of bone marrow function. Brit J Haematol 71 (1989) 457-462
43. Murphy W.J., Durum S.K., Anver M.R., and Longo D.L. Immunologic and hematologic effects of neuroendocrine hormones. J Immunol 148 (1992) 3799-3805
44. Maloof P.B., Joshi D.D., Qian J., Gascon P., Singh D., and Rameshwar P. Induction of preprotachykinin-I and neurokinin-1 by adrenocorticotropin and prolactin. Implication for neuroendocrine-immune-hematopoietic axis. J Neuroimmunol 112 (2001) 188-196
45. Dogusan Z., Book M.L., Verdood P., Yu-Lee L.Y., and Hooghe-Peters E.L. Prolactin activates interferon regulatory factor-1 expression, in normal lympho-hemopoietic cells. Eur Cytokine Netw 11 (2000) 435-442
46. Morales P., Carretero M.V., Geronimo H., Copin S.G., Gaspar M.L., Marcos M.A., and Martin-Perez J. Influence of prolactin on the differentiation of mouse B-lymphoid precursors. Cell Growth Differ 10 (1999) 583-590
47. Richards S.M., and Murphy W.J. Use of human prolactin as a therapeutic protein to potentiate immunorhematopoietic function. J Neuroimmunol 109 (2000) 56-62
48. Bellone G., Geuna M., and Carbone A. Regulatory action of prolactin on the in vitro growth of CD34+ve human hemopoietic progenitor cells. J Cell Physiol 163 (1995) 221-231
49. Merchav S., Tatarsky I., and Hochberg Z. Enhancement of human granulopoiesis in vitro by biosynthetic insulin-like growth factor I/somatomedin C and human growth hormone. J. Clin Invet 81 (1988) 791-797
50. Merchav S., Tatarsky I., and Hochberg Z. Enhancement of erythropoiesis in vitro by human growth hormone is mediated by insulin-like growth factor-I. Brit J Haematol 70 (1988) 267-271
51. Jardieu P., Clark R., Mortensen D., and Dorshkind K. In vivo administration of insulin-like growth factor-I stimulates primary B lymphopoiesis and enhances lymphocyte recovery after bone marrow transplantation. J Immunol 152 (1994) 4320-4327
52. Bhat G., Gupta S.K., and Maiti B.R. Influence of prolactin on mitogenic activity of the bursa of Fabricius of the chick. Gen Comp Endocrinol 52 (1983) 452-455
53. Skwarlo-Sonta K., Sotowaska-Brochocka J., and Rosolowska-Huszez D. Effect of prolactin on the diurnal changes in immune parameters and plasma corticosterone in white leghorn chickens. Acta Endocrinol 116 (1987) 172-178
54. Fr{high symbol}nkel-Conrat H., and Li C.H. Hormonal effects on the nucleic acid and phospholipid turnover of rat liver and thymus. Endocrinology 44 (1949) 487-491
55. Baroni C.D., Fabris N., and Bertoli G. Effects of hormones on development and function of lymphoid tissues: Synergistic action of thyroxin and somatotropic hormone in pituitary dwarf mice. Immunology 17 (1969) 303-314
56. Baroni C.D., Pesando P.C., and Bertoli G. Effects of hormones on development and function of lymphoid tissues II: Delayed development of immunological capacity in pituitary dwarf mice. Immunology 21 (1971) 455-461
57. Pandian M.R., and Talwar G.P. Effect of growth hormone on the metabolism of thymus and on the immune response against sheep erythrocytes. J Exp Med 134 (1971) 1095-1113
58. 3 pituitary adenoma cells can reverse thymic aging in rats. Proc Natl Acad Sci USA 83 (1986) 5663-5667
59. Berczi I. Pituitary Function and Immunity (1986), CRC Press, Boca Raton, Florida
60. Berczi I., Nagy E., DeToledo S.M., Matusik R.J., and Friesen H.G. Pituitary hormones regulate cmyc and DNA synthesis in lymphoid tissue. J Immunol 146 (1991) 2201-2206
61. Timsit J., Savino W., and Safieh B. Growth hormone and insulin-like growth factor-I stimulate hormonal function and proliferation of thymic epithelial cells. J Clin Endocrinol Metab 75 (1992) 183-188
62. Savino W., Mello-Coelho V., and Dardenne M. Neuroendocrine control of the thymic microenvironment: role of pituitary hormones. In: Berczi I., and Szelenyi J. (Eds). Advances in Psychoneuroimmunology (1994), Plenum Press, New York 75-82
63. Yamada M., Hato F., and Kinoshita Y. The indirect participation of growth hormone in the thymocyte proliferation system. Cell Mol Biol Noisy le Grand 40 (1994) 111-121
64. Taub D.D., Tsarfaty G., and Lloyd A.R. Growth hormone promotes human T cell adhesion and migration to both human and murine matrix proteins in vitro and directly promotes xenogeneic engraftment. J Clin Invest 94 (1994) 293-300
65. Esquifino A.I., Vallanua M.A., Szary A., Yau J., and Bartke A. Ecotopic pituitary transplants restore immunocompetence in Ames dwarf mice. Acta Endocrinol 125 (1991) 67-72
66. Singh U., and Owen J.J.T. Studies on the maturation of the thymus stem cells: The effects of catecholamines, histamines and peptide hormones on the expression of T cell alloantigens. Eur J Immunol 6 (1976) 59-62
67. Russell D.H., Mills K.T., Talamantes R.J., and Bern H.A. Neonatal administration of prolactin antiserum alters the developmental pattern of T- and B- lymphocytes in the thymus and spleen of BALB/c female mice. Proc Natl Acad Sci USa 85 (1988) 7404-7407
68. Arezzini C., DeGori V., Tarli P., and Neri P. Weight increase of body and lymphatic tissues in dwarf mice treated with human chorionic somatomammotropin (HCS). Proc Soc Exp Biol Med 141 (1972) 98-100
69. Guicheux J., Heymann D., Gouin F., Pilet P., Faivre A., and Daculsi G. Growth hormone stimulates multinucleated cell formation in long-term bone marrow cultures. Eur J Cell Biol (1998) 7559-7565
70. Spangelo B.L., Hall N.R.S., Ross P.C., and Goldstein A.L. Stimulation of in vivo antibody production and concanavalin-A-induced mouse spleen cell mitogenesis by prolactin. Immunopharmacology 14 (1987) 11-20
71. Cross R.J., Campbell J.L., Markesbery W.R., and Roszman T.L. Transplantation of pituitary grafts fail to restore immune function and to reconstitute the thymus glands of aged mice. Mech Aging Develop 56 (1990) 11-22
72. Sotowaska-Brochocka J., Rosolowska-Huszcz D., Skwarlo-Sonta, and Gajewska A. Effect of exogenous prolactin on immunity in chickens. Res Vet Science 37 (1984) 123-125
73. Castro A.G., Hauser T.M., Cocks B.G., Abrams J., Zurawski S., Churakova T., Zonin F., Robinson D., Tangye S.G., Aversa G., Nichols K.E., de Vries J.E., Lanier L.L., and O'Garra A. Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): differential expression and responsiveness in Th1 and Th2 cells. J Immunol 163 (1999) 5860-5870
74. Rapaport R., Oleske J., and Ahdieh H. Suppression of immune function in growth hormone deficient children during treatment with human growth hormone. J Pediat 109 (1986) 434-439
75. Rapaport R., Oleske J., and Ahdieh H. Effects of human growth hormone on immune functions: In vitro studies on cells of normal and growth hormone-deficient children. Life Sci 41 (1987) 2319-2324
76. Yoshida A., Ishioka C., Kimata H., and Mikawa H. Recombinant human growth hormone stimulates B-cell immunoglobulin synthesis and proliferation in serum-free medium. Acta Endocrinol 126 (1992) 524-529
77. Kimata H., and Yoshida A. Effect of growth hormone and insulin-like growth factor-I on immunoglobulin production by and growth of human B cells. J Clin Endocrinol Metab 78 (1994) 635-641
78. Kimata H., and Fujimoto M. Growth hormone and insulin-like growth factor I induce immunoglobulin IgE and IgG4 production by human B cells. J Exp Med 180 (1994) 727-732
79. Fornari M.C., Scolnik M.P., and Palacios M.F. Growth hormone inhibits normal B-cell differentiation and neutrophils chemotaxis in vitro. Int J Immunopharmacol 16 (1994) 667-673
80. Merimee T.J., Grant M.B., and Broder C.M. Insulin-like growth factor secretion by human B-lymphocytes: a comparison of cells from normal and pygmy subjects. J Clin Endocrinol Metab 69 (1989) 978-984
81. Yakar S., Damene H., and Meiden R. Growth hormone (GH) stimulates insulin-like growth factor-I (IGF-I) and IGF-binding protein (IGFBP)-2 gene expression in spleens of juvenile rats. Hormones Metab Res 26 (1994) 363-366
82. Richards S.M., Garman R.D., Keyes L., Kavanagh B., and McPherson J.M. Prolactin is an antagonist of TGF-beta activity and promotes proliferation of murine B cell hybridomas. Cell Immunol 184 (1998) 85-91
83. Yada T., Nagae M., Moriyama S., and Azuma T. Effects of prolactin and growth hormone on plasma immunoglobulin M levels of hypophysectomized rainbow trout, Oncorhynchus mykiss. Gen Comp Endocrinol 115 (1999) 46-52
84. LeRoith D., Yanowski J., Kaldjian E.P., Jaffe E.S., LeRoith T., Purdue K., Cooper B.C., Pyle R., and Adler W. The effects of growth hormone and insulin-like growth factor I on the immune system of aged female monkeys. Endocrinology 137 (1996) 1071-1079
85. Lebl J., Sediva A., Snajderova M., Pruhova S., and Rakosnikova V. Immune system in adults with childhood-onset growth hormone deficiency: Effect of growth hormone therapy. Endocr Regul 34 (2000) 169-173
86. Matera L., Galetto A., Geuna M., Vekemans K., Ricotti E., Contarini M., Moro F., and Basso G. Individual and combined effect of granulocyte-macrophage colony-stimulating factor and prolactin on maturation of dendritic cells from blood monocytes under serum-free conditions. Immunology 100 (2000) 29-36
87. Nagy E., and Berczi I. Immunodeficiency in hypophysectomized rats. Acta Endocrinol 89 (1978) 530-537
88. Berczi I., Nagy E., Asa S.L., and Kovacs K. Pituitary hormones and contact sensitivity in rats. Allergy 38 (1983) 325-330
89. Hiestand P.C., Gale J.M., and Melker P. Soft immunosuppression by inibition of prolactin release: synergism with cyclosporine in kidney allograft survival and in the localizedgraft-versus-host reaction. Transplant Proc 18 (1986) 870-872
90. Hiestand P.C., Melker P., Nordmann R., Grieder A., and Permongkol C. Prolactin as a modulator of lymphocyte responsiveness provides a possible mechanism of action for cyclosporine. Proc Natl Acad Sci USA 83 (1986) 2599-2603
91. Wilner M.L., Ettenger R.B., Koyle M.A., and Rosenthal J.T. The effect of hypoprolactinemia alone and in combination with cyclosporine on allograft rejection. Transplantation 49 (1990) 264-267
92. Shen G.K., Montgomery D.W., and Ulrich E.D. Upregulation of prolactin gene expression and feedback modulation of lymphocyte proliferation during acute allograft rejection. Surgery 112 (1992) 387-393
93. Bernton E.W., Meltzer M.T., and Holaday J.W. Suppression of macrophage activation and T-lymphocyte function in hypoprolactinemic mice. Science 239 (1988) 401-404
94. Cosson C., Myara I., and Guillemain R. Serum prolactin as a rejection marker in heart transplantation. Clin Chem 35 (1989) 492
95. Matera L., Cesano A., Bellone G., and Oberholtzer E. Modulatory effect of prolactin on the resting and mitogen-induced activity of T, B and NK lymphocytes. Brain Behav Immun 6 (1992) 409-417
96. Athreya B.H., Pletcher J., and Zulian F. Subset-specific effects of sex hormones and pituitary gonadotropins on human lymphocyte proliferation in vitro. Clin Immunol Immunopathol 66 (1993) 201-211
97. Matera L., Contarini M., Bellone G., Forno B., and Biglino A. Up-modulation of interferon-γ mediates the enhancement of spontaneous cytotoxicity in prolactin-activated natural killer cells. Immunology 98 (1999) 386-392
98. Gala R.R., and Shevach E.M. Influence of prolactin and growth hormone on the activation of dwarf mouse lymphocytes in vivo. Proc Soc Exp Biol Med 204 (1993) 224-230
99. Postel-Vinay M.C., de Mello Coelho V., Gagnerault M.C., and Dardenne M. Growth hormone stimulates the proliferation of activated mouse T lymphocytes. Endocrinology 138 (1997) 1816-1820
100. Yamashita Y., Hashimoto Y., Honjo M., and Yamashita N. The effect of growth hormone on the proliferation of human Th cell clones. Life Sci 66 (2000) 1929-1935
101. Geffner M., Bersch N., and Lippe B.M. Growth hormone mediates the growth of T-lymphoblast cell lines via locally generated insulin-like growth factor-I. J Clin Endocrinol Metab 71 (1990) 464-469
102. Baxter J.B., Blalock J.E., and Weigent D.A. Characterization of immunoreactive insulin-like growth factor-I from leukocytes and its regulation by growth hormone. Endocrinology 129 (1991) 1727-1734
103. Tyden G., Berg U., and Reinholt F. Acute renal graft rejection after treatment with human growth hormone. Lancet 336 (1990) 1455-1456
104. (letter). Yordam N., Kandemir N., Topaloglu H., Gogus S., and Kucukalu T. Myositis associated with growth hormone therapy. J Pediat 125 (1994) 671
105. Span J.P., Pieters G.F., Smals A.G., Koopmans P.P., and Kloppenborg P.W. Number and percentage of NK-cells are decreased in growth hormone-deficient adults. Clin Immunol Immunopathol 78 (1996) 90-92
106. Rongen-Westerlaken C., Rijkers G.T., and Scholtens E.J. Immunologic studies in Turner syndrome before and during treatment with growth hormone. J Pediat 119 (1991) 268-272
107. Crist D.M., Peake G.T., and Mackinnon L.T. Exogenous growth hormone treatment alters body composition and increases natural killer cell activity in women with impaired endogenous growth hormone secretion. Metabolism 36 (1987) 1115-1117
108. Crist D.M., and Kraner J.C. Supplemental growth hormone increases the tumor cytotoxic activity of natural killer cells in healthy adults with normal growth hormone secretion. Metabolism 39 (1990) 1320-1324
109. Matera L., Cesano A., Muccioli G., and Veglia F. Modulatory effect of prolactin on the DNA synthesis rate and NK activity of large granular lymphocytes. Int J Neurosci 51 (1990) 265-267
110. Cesano A., Oberholtzer E., and Contarini M. Independent and synergistic effect of interleukin-2 and prolactin on development of T- and NK-derived LAK effectors. Immunopharmacology 28 (1994) 67-75
111. Bidlingmaier M., Auernhammer C.J., Feldmeier H., and Strasburger C.J. Effects of growth hormone and insulin-like growth factor I binding to natural killer cells. Acta Paediatr Suppl 423 (1997) 80-81
112. Wiedermann C.J., Reinisch N., and Braunsteiner H. Stimulation of monocyte chemotaxis by human growth hormone and its deactivation by somatostatin. Blood 82 (1993) 954-960
113. Manfredi R., Turnietto F., and Azzaroli L. Growth hormone (GH) and the immune system: imparied phagocytic function in children with idiopathic GH deficiency is corrected by treatment with biocynthetic GH. J Pediat Endocrinol 7 (1994) 245-251
114. 2. J Immunol 154 (1995) 1909-1918
115. Gaytan F., Romero J.L., and Bellido C. Effects of growth hormone and prolactin on testicular macrophages in long-term hypophysectomized rats. J Repord Immunol 27 (1994) 73-84
116. Rovensky J., Ferencikova J., and Vigas M. Effect of growth hormone on the activity of some lysosomal enzymes in neutrophilic polymorphonuclear leukocytes of hypopituitary dwarfs. Int J Tissue React 7 (1985) 153-159
117. Wiedermann C.J., Niedermuhlbicher M., and Geissler D. Priming of normal human neutrophils by recombinant human growth hormone. Brit J. H{high symbol}matol 78 (1991) 19-22
118. Fu Y.K., Arkins S., and Li Y.M. Reduction in superoxide anion secretion and bactericidal activity of neutrophils from aged rats: reversal by the combination of gamma inferferon and growth hormone. Infect Immun 62 (1994) 1-8
119. Cecilia-Fornari M., Fernanda-Palacios M., Diez R.A., and Intebi A.D. Decreased chemotaxis of neutrophils in acromegaly and hyperprolactinemia. Eur J Endocrinol 130 (1994) 463-468
120. Matsuda T., Saito H., Inoue T., Fukatsu K., Han I., Furukawa S., Ikeda S., Muto T., and Growth h.i.a.a.u.-r.r.o.i.p.b.h.p.n. JPEN J Parenter Enteral Nutr 22 (1998) 368-374
121. Cesario T.C., Yousefi S., and Carandang G. Enhanced yields of gamma interferon in prolactin treated human peripheral blood mononuclear cells. Proc Soc Exp Biol Med 205 (1994) 89-95
122. Edwards C.K., Ghiasuddin S.M., and Yunger L.M. In vivo administration of recombinant growth hormone or gamma-interferon activates macrophages: Enhanced resistance to experimentalSalmonella-typhimurium infection is correlated with generation of reactive oxygen intermediates. Infec Immun 60 (1992) 2514-2521
123. Kelley K.W., Arkins S., and Li Y.M. Growth hormone, prolactin and insulin-like growth factors: New jobs for old players. Brain Behav Immun 6 (1992) 317-326
124. Galdiero M., Donnarumma G., Cipollareo de L'Ero G., Marcatili A., Scarfogliero P., and Sommesse L. Effect of growth hormone, prolactin and insulin on the release of the IL-1 alpha, IFN-gamma and IL-4 by staphylococcal enterotoxin A-stimulatedsplenocytes. Euro Cytokine Netw 6 (1995) 187-194
125. Thellin O., Coumans B., Devos S., Hooghe-Peters E.L., Zorzi W., Igout A., Heinen E., and Hooghe R. Limited effects of placental and pituitary growth hormone on cytokine expression in vitro. Eur Cytokine Netw 11 (2000) 452-455
126. Galdiero M., Vitiello M., Scarfogliero P., and Sommese L. Growth hormone release of interleukin-1 alpha, interferon-gamma and, interleukin-4 from murine splenocytes stimulated with staphylococcal protein A, toxic shock syndrome toxin-1 and streptococcal lysin S. Eur Cytokine Netw 8 (1997) 83-90
127. Elsasser T.H., Fayer R., Rumsey T.S., and Hartnell G.F. Recombinant bovine somatotropin blunts plasma turmor necrosis factor-alpha, cortisol, and thromboxane-B2 responses to endotoxin in vivo. Endocrinology 134 (1994) 1082-1088
128. Zarkesh-Esfahani S.H., Kolstad O., Metcalfe R.A., Watson P.F., von Laue S., Walters S., Revhaug A., Weetman A.P., and Ross R.J. High-dose growth hormone does not affect proinflammatory cytokine (tumor necrosis factor-alpha, interlcukin-6, and interferon-gamma) release fromactivated peripheral blood mononuclear cells or after minimal to moderate surgical stress. J Clin Endocrinol Metab 85 (2000) 3383-3390
129. Corbacho A.M., Nava G., Eiserich J.P., Noris G., Macotela Y., Struman I., Martinez De La Escalera G., Freeman B.A., and Clapp C. Proteolytic cleavage confers nitric oxide synthase inducing activity upon prolactin. J Biol Chem 275 (2000) 13183-13186
130. Derfalvi B., Igaz P., Fulop K.A., Szalai C., and Falus A. Interleukin-6-induced production of type II acute phase proteins and expression of junB gene are downregulated by human recombinant growth hormone invitro. Cell Biol Int 24 (2000) 109-114
131. Montgomery D.W., Zukoski C.F., and Shah G.N. Concavalin A-stimulated murine splenocytes produce a factor with prolactin-like bioactivity and immunoreactivity. Biochem Biophys Res Commun 145 (1987) 692-698
132. Hartmann D.P., Holaday J.W., and Bernton D.W. Inhibition of lymphocyte proliferation by antibodies to prolactin. FASEB J 3 (1989) 2194-2202
133. DiMattia G.E., Gellersen B., Bohnet H.G., and Friesen H.G. A human B-lymphoblastoid cell line produces prolactin. Endocrinology 122 (1988) 2508-2517
134. Hatfill S.J., Kirby R., and Hanley M. Hyperprolactinemia in acute myeloid leukemia and indication of ectopic expression of human prolactin in blast cells of a patient subtype M4. Leukemia Res 14 (1990) 57-62
135. Montgomery D.W., LeFevre J.A., and Ulrich E.D. Identification of prolactin-like proteins synthesized by normal murine lymphocytes. Endocrinology 127 (1990) 2601-2603
136. Montomery D.W., Shen G.K., and Ulrich E.D. Human thymocytes express a prolactin-like messenger ribonucleic acid and synthesize bioactive prolactin-like proteins. Endocrinology 131 (1992) 3019-3026
137. Wu H., Devi R., and Malarkey W.B. Expression and localization of prolactin messenger ribonucleic acid in the human immune system. Endocrinology 137 (1996) 349-353
138. DiMattia G.E., Gellersen B., Duckworth M.L., and Friesen H.G. Human prolactin gene expression: The use of an alternative noncoding exon in decidua and the IM-9_P3 lymphoblastoid cell line. J Biol Chem 265 (1990) 16412-16421
139. Gellersen B., DiMattia G.E., Friesen H.B., and Bohnet H.G. Regulations of prolactin secretion in the human B-lymphoblastoid cell line IM-9-P3 by dexamethasone but not other regulators of pituitary prolactinsecretion. Endocrinology 125 (1989) 2853-2861
140. Gellersen B., DiMattia G.E., Friesen H.G., and Bohnet H.G. Prolactin (PRL) mRNA from human decidua differs from pituitary PRL, mRNA, but resembles the IM-9-P3 lymphoblast PRL transcript. Mol Cell Endocrinol 64 (1989) 127-130
141. Gellersen B., Kempf R., Telgmann R., and DiMattia G.E. Nonpituitary human prolactin gene transcription is independent of Pit-1 and differentially controlled in lymphocytes and in endometrial stroma. Mol Endocrinol 8 (1994) 356-373
142. Rapaport R.G., and Bozzola M. Role of B-cells in growth hormone-immune interactions. Acta Paediatr Suppl 423 (1997) 82-83
143. Delhase M., Vergani P., Malur A., Hooghe Peters E.L., and Hooghe R.J. The transcription factor Pit-1/HGF-1 is expressed in hematopoietic and lymphoid tissues. Eur J Immunol 23 (1993) 951-955
144. Hooghe R.J., and Hooghe-Peters E.L. The developmental biology of the anterior pituitary: A biased review. Grwwth hormone prolactin and insulin-like growth factor-I as lymphohemopoietic cytokines (1995), RG Landes Co., Texas 3-34
145. Chen H.T., Schuler L.A., and Schultz R.D. Growth hormone and Pit-1 expression in bovine fetal lymphoid cells. Domest Anim Endocrinol 14 (1997) 399-407
146. Melen L., Hennen G., Dullaart R.P., Heinen E., and Igout A. Both pituitary and placental growth hormone transcripts are expresed in human peripheral blood mononuclear cells (PBMC). Clin Exp Immunol 110 (1997) 336-340
147. Reem G.H., Ray D.W., and Davis J.R. The human prolactin gene upstream promoter is regulated in lymphoid cells by activators of T-cells and by cAMP. J Mol Endocrinol 22 (1999) 285-292
148. Yang Y., Guo L., Ma L., and Liu X. Expression of growth hormone and insulin-like growth factor in the immune system of children. Horm Metab Res 31 (1999) 380-384
149. Geffner M. Effects of growth hormone and insulin-like growth factor I on T- and B-lymphocytes and immune function. Acta Paediatr Suppl 423 (1997) 76-79
150. Buul-Offers S.v., and Koojiman R. The role of growth hormone and insulin-like growth factors in the immune system. Cell Mol Life Sci 54 (1998) 1083-1094
151. Nagafuchi H., Suzuki N., Kaneko A., Asai T., and Sakane T. Prolactin locally produced by synovium infiltrating T lymphocytes induces excessive synovial cell functions in patients with rheumatoid arthritis. J Rheumatol 26 (1999) 1890-1900
152. Foster M.P., Jensen E.R., Montecino-Rodriguez E., Leathers H., Horseman N., and Dorshkind K. Humoral and cell-mediated immunity in mice genetic deficiences of prolactin, growth hormone, insulin-like growth factor-I, and thyroid hormone. Clin Immunol 96 (2000) 140-149
153. Dorshkind K., and Horseman N.D. The roles of prolactin, growth hormone, insulin-like growth factor-I, and thyroid hormones in lymphocyte development and function: insights from genetic models of hormone and hormone receptor deficiency. Endocr Rev 21 (2000) 292-312
154. Bouchard B., Ormandy C.J., Di Santo J.P., and Kelly P.A. Immune system development and function in prolactin receptor-deficient mice. J Immunol 163 (1999) 576-582
155. Kooijman R., Buul-Offers S.v., Scholtens E.J., Schuurman H.J., Brande J.V.d., and Zegers Z.J.M. Cell development in insulin-like growth factor II transgenic mice. J Immunol 154 (1995) 5736-5745
156. Kooijman R., Buul-Offers S.v., Scholtens L.E., Reijnen-Gresnight R.G., and Zegers B.J.M. T and B cell development in pituitary deficient insulin-like growth factor-II transgenic dwarf mice. J Endocrinol 155 (1997) 165-170
157. Helderman J.H., and Strom T.B. Specific insulin binding site on T and B lymphocytes as a marker of cell activation. Nature 274 (1978) 62-63
158. Berman J.S., and Center D.M. Chemotactic activity of porcine insulin for human T lymphocytes in vitro. J Immunol 138 (1987) 2100-2103
159. Berczi I. Hormonal interactions between the pituitary and immune system. In: Grossman C.J. (Ed). Bilateral Communication Between the Endocrine and Immune Systems (1994) 96-144
160. Kabadi U.M., Reust C.S., and Kabadi M.U. Weight gain, improvement in metabolic profile, and CD4 count with insulin administration in an AIDS patient. AIDS Patient Ce STDS 14 (2000) 575-579
161. Mynarcik D.C., McNurlan M.A., Steigbigel R.T., Fuhrer J., and Gelato M.C. Association of severe insulin resistance with both loss of limb fat and clevated serum tumor necrosis factor receptor levels in HIV lipodystrophy. J Acquir Immune Defic Syndr 25 (2000) 312-321
162. Shikuma C.M., Waslien C., McKeague J., Baker N., Arakaki M., Cui X.W., Souza S., Imrie A., and Arakaki R. Fasting hyperinsulinemia and increased waist-to-hip ratios in non-wasting individuals with AIDS. AIDS 13 (1999) 1359-1365
163. Gyarmati J., Szekeres-Bartho J., Fischer B., and Soltesz G. Fetal type lymphocytes in insulin dependent diabetes mellitus. Autoimmunity 30 (1999) 63-69
164. Fernandez-Real J.M., and Ricart W. Insulin resistance and inflammation in an evolutionary perspective: the contribution of cytokine genotype/phenotype to thriftiness. Diabetologia 42 (1999) 1367-1374
165. del Aguila L.F., Claffey K.P., and Kirwan J.P. TNF-alpha impairs insulin signaling and insulin stimulation of glucose uptake in C2C12 muscle cells. Am J Physiol 276 (1999) E849-E855
166. Cseh K., Baranyi E., and Winkler G. The role of cytokines of the innate and adaptive immune system in the regulation of insulin resistnace. Diebetologia 42 (1999) 497-498
167. Fliser D., Pacini G., Engelleiter R., Kautzky-Willer A., Prager R., Franek E., and Ritz E. Insulin resistance and hyperinsulinemia are already present in patients with incipient renal disease. Kidney Int 53 (1998) 1343-1347
168. Benigni F., Atsumi T., Calandra T., Metz C., Echtenacher B., Peng T., and Bucala R. The proinflammatory mediator macrophage migration
169. Waeber G., Calandra T., Bonny C., and Bucala R. A role for the endocrine and pro-inflammatory mediator MIF in the control of insulin secretion during stress. Diabetes Metab Res Rev 15 (1999) 47-54
170. Martins T.C., and Aguas A.P. NOD mice are resistant to depletion of thymic cells caused by acute stress or infection. Autoimmunity 29 (1999) 273-280
171. Throsby M., Pleau J., Dardenne M., and Homo-Delarche F. Thymic expression of the pancreatic endocrine hormones. Neuroimmunomodulation 6 (1999) 108-114
172. Morishita S., Sato E.F., Takahashi K., Manabe M., and Inoue M. Insulin-induced hypoglycemia elicits thymocyte apoptosis in the rat. Diabetes Res Clin Pract 40 (1998) 1-7
173. Kido Y., Nakae J., and Accilli D. The insulin receptor and its cellular targets. J. Clin Endocrinol Metab 86 (2001) 972-979