Requirement of PI3-kinase activity for the nuclear transport of prolactin in cloned murine T lymphocytes

Journal of Neuroimmunology

Volumn 94, Issue 1-2, 1999, Pages 40-47

  Belkowski, Stanley M ^a   Levine, Jason E ^a   Prystowsky, Michael B ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

PI3 kinase; Prolactin; Rapamycin; T cell activation; Wortmannin

Indexed keywords

INTERLEUKIN 2; PROLACTIN;

ANIMAL CELL; ARTICLE; ENZYME ACTIVITY; IMMUNOREGULATION; LYMPHOCYTE PROLIFERATION; MOUSE; NEUROIMMUNOLOGY; NONHUMAN; PRIORITY JOURNAL; PROLACTIN RELEASE; PROTEIN TRANSPORT; T LYMPHOCYTE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCITRIOL; CELL DIVISION; CELL NUCLEUS; CHROMONES; CLONE CELLS; ENZYME INHIBITORS; FLUORESCENT DYES; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-2; ISOQUINOLINES; MICE; MORPHOLINES; NUCLEAR LOCALIZATION SIGNALS; PROLACTIN; SIROLIMUS; T-LYMPHOCYTES;

EID: 0033081686     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(98)00202-1     Document Type: Article

References (57)

1. Aagaard-Tillery K.M., Jelinek D.F. A role for phosphatidylinositol 3-kinase in generating T cell help for B cell growth and differentiation. J. Immunol. 157:1996;2769-2778.
2. Andrews G.K., Varma S., Ebner K.E. Regulation of expression of c-fos and c-myc in rat lymphoma Nb-2 cells. Biochimica et Biophysica Acta. 909:1987;231-236.
3. 125I -βNGF Brain Research. 761:1997;257-262.
4. Berczi I., Nagy E., Kovacs K., Horvath E. Regulation of humoral immunity in rats by pituitary hormones. Acta Endocrin. 98:1981;506-513.
5. Beretta L., Gingras A.-C., Svitkin Y.V., Hall M., Sonenberg N. Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. The EMBO Journal. 15:1996;658-664.
6. Bernton E.W., Meltzer M.S., Holaday J.W. Suppression of macrophage activation and T lymphocyte function in hypoprolactinemic mice. Science. 239:1988;401-404.
7. Brown E.J., Albers M.W., Shin T.B., Ichikawa K., Keith C.T., Lane W.S., Schreiber S.L. A mammalian protein targeted by G1 arresting rapamycin receptor complex. Nature. 369:1994;756-758.
8. S6 kinase by kinase activity of FRAP in vivo. Nature. 377:1995;441-446.
9. Brown E.J., Schreiber S.L. A signaling pathway to translational control. Cell. 86:1996;517-520.
10. Brunn G.J., Williams J., Sabers C., Wiederrecht G., Lawrence J.C., Abraham R.T. Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. The EMBO Journal. 15:1996;5256-5267.
11. Brunn G.J., Hudson C.C., Sekulic A., Williams J.M., Hosoi H., Houghton P.J., Lawrence J.C., Abraham R.T. Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin. Science. 277:1997;99-101.
12. Calvo V., Crews C.M., Vik T.A., Bierer B.E. Interleukin 2 stimulation of p70 Ss6 kinase activity is inhibited by the immunosuppressant rapamycin. Proc. Natl. Acad. Sci. USA. 89:1992;7571-7575.
13. S6 kinase, DNA synthesis, and glucose transporter translocation. Mol. Cell Biol. 14:1994;4902-4911.
14. Clevenger C., Altmann S.W., Prystowsky M.B. Requirement of nuclear prolactin for interleukin 2 stimulated proliferation of T lymphocytes. Science. 253:1991;77-79.
15. Clevenger C.V., Russell D.H., Appasamy P.M., Prystowsky M.B. Regulation of interleukin 2-driven T-lymphocyte proliferation by prolactin. Proc. Natl. Acad. Sci. USA. 87:1990;6460-6464.
16. Clevenger C.V., Sillman A.L., Prystowsky M.B. Interleukin-2 driven nuclear translocation of prolactin in cloned T-lymphocytes. Endocrinology. 127:1990;3151-3159.
17. Clevenger C.V., Sillman A.L., Hanley-Hyde J., Prystowsky M.B. Requirement for prolactin during cell cycle regulated gene expression in cloned T lymphocytes. Endocrinology. 130:1992;3216-3222.
18. Crawley J.B., Rawlinson L., Lali F.V., Page T.H., Saklatvala J., Foxwell B.M.J. T cell proliferation in response to interleukin 2 and 7 requires p38MAP kinase activation. J. Biol. Chem. 272:1997;15023-15027.
19. Dudek H., Datta S.R., Franke T.F., Birnbaum M.J., Yao R., Cooper G.M., Segal R.A., Kaplan D.R., Greenberg M.E. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science. 275:1997;661-665.
20. Dumont F.J., Staruch M.J., Koprak S.L., Melino M.R., Sigal N.H. Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin. J. Immunol. 144:1990;251-258.
21. Feuerstein N., Huang D., Prystowsky M.B. Rapamycin selectively blocks IL-2 induced PCNA gene expression in T lymphocytes: evidence for inhibition of CREB/ATF binding activities. J. Biol. Chem. 270:1995;9454-9458.
22. Glasebrook A.L., Fitch F.W. Alloreactive cloned T cell lines: I. Interactions between cloned amplifier and cytolytic T cell lines. J. Exp. Med. 151:1980;876-895.
23. Gout, P.W., Beer, C.T., deJong, G., Rennie, P.S., Bruchovsky, N. (1988). Prolactin induced generation of transferrin receptors: a critical event in the mitogensis of lactogen dependent Nb2 node rat lymphoma cells. Hormones and Cancer, 242-245.
24. Hartmann D.P., Holoday J.W., Bernton E.W. Inhibition of lymphocyte proliferation by antibodies to prolactin. FASEB J. 3:1989;2194-2202.
25. Helliwell S.B., Wagner P., Kunz J., Deuter-Reinhard M., Henriquez R., Hall M.N. TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast. Mol. Biol. Cell. 5:1994;105-118.
26. Iordanov I., Bender K., Ade T., Shmid W., Sachsenmaier C., Engel K., Gaestel M., Rahmsdorf H.J., Herrlich P. CREB is activated by UVC through a p38/HOG-1-dependent protein kinase. The EMBO Journal. 16:1997;1009-1022.
27. Jess T.J., Belham C.M., Thomson F.J., Scott P.H., Plevin R.J., Gould G.W. Phosphatidylinositol 3′-kinase,but not p70 ribosomal S6 kinase, is involved in membrane protein recycling: wortmannin inhibits glucose transport and downregulates cell-surface transferrin receptor numbers independently of any effect on fluid-phase endocytosis in fibroblasts. Cellul. Signall. 8:1996;297-304.
28. Joly M., Kazlauskas A., Corvera S. Phosphidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor trafficking. J. Biol. Chem. 270:1995;13225-13230.
29. Josefsberg Z., Posner B.I., Patel B., Bergeron J.J.M. The uptake of prolactin into female rat liver. J. Biol. Chem. 254:1979;209-215.
30. Karnitz L.M., Burns L.A., Sutor S.L., Blenis J., Abraham R.T. Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway. Mol. Cell. Biol. 15:1995;3049-3057.
31. Kelly P.A., Djiane J., Postel-Vinay M.C., Edery M. The prolactin/growth hormone receptor family. Endo. Revs. 12(3):1991;235-251.
32. Lee S.C., Sabath D.E., Deutsch C., Prystowsky M.B. Increased voltage-gated potassium conductance during interleukin 2-stimulated proliferation of a mouse helper T lymphocyte clone. J. Cell. Biol. 102:1986;1200-1208.
33. Levine J.E., Prystowsky M.B. Polypeptide growth factors in the nucleus: a review of function and translocation. Neuroimmunomodulation. 2:1995;290-298.
34. kip1. Mol. Cell. Biol. 16:1996;6744-6751.
35. Martys J.L., Wjasow C., Gang D.M., Kielian M.C., McGraw T.E., Backer J.M. Wortmannin-sensitive trafficking pathways in chinese hamster ovary cells. J. Biol. Chem. 271:1996;10953-10962.
36. Matera L., Muccioli G., Cesano A., Bellussi G., Genazzani E. Prolactin receptors on large granular lymphocytes dual regulation by cyclosporin A. BBI. 2:1988;1-10.
37. Monfar M., Lemon K.P., Grammer T.C., Cheatham L., Chung J., Vlahos C.J., Blenis J. Activation of pp70/85 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP. Mol. Cell. Biol. 15:1995;326-337.
38. Monfar M., Lemon K.P., Grammer T.C., Cheatham L., Chung J., Vlahos C.J., Blenis J. Activation of pp70/85 S6 kinases in interleukin 2 responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP. Molecular and Cellular Biology. 15:1995;326-337.
39. Montgomery D.W., Zukoski C.F., Shah G.N., Buckley A.R., Pacholcyzk T., Russell D.H. Concanavalin A-stimulated murine splenocytes produce a factor with prolactin-like bioactivity and immunoreactivity. Biochem. and Biophys. Res. Comm. 145:1987;692-698.
40. Mukherjee P., Mastro A.M., Hymer W.C. Prolactin induction of interleukin 2 receptors on rat splenic lymphocytes. Endocrinology. 126:1990;88-93.
41. Nagy E., Berczi I., Wren G.E., Asa S.L., Kovacs K. Immunomodulation by bromocryptine. Immunopharmacology. 6:1983;231-243.
42. Nagy E., Berczi I. Immunodeficiency in hypophysectomized rats. Acta. Endocrin. 89:1978;530-537.
43. Nagy E., Berczi I. Hypophysectomized rats depend on residual prolactin for survival. Endocrinology. 128:1991;2776-2784.
44. Pellegrini I., Lebrun J.J., Ali S., Kelly P.A. Expression of prolactin and its receptor in human lymphoid cells. Molecular Endocrinology. 6:1992;1023-1031.
45. Prystowsky M.B., Khan K.M., Marovitz W.F. Detection of H2-b and Thy-1.2 surface antigens on the differentiating murine otocyst using Nomarski optics. Differentiation. 12:1978;53-58.
46. Rao Y.-P., Olson M.D., Buckley D.J., Buckley A.R. Nuclear co-localization of prolactin and the prolactin receptor in rat Nb2 node lymphoma cells. Endocrinology. 133:1993;3062-3065.
47. Rao Y.-P., Buckley D.J., Olson M.D., Buckley A.R. Nuclear translocation of prolactin: collaboration of tyrosine kinase and protein kinase C activation in rat Nb2 node lymphoma cells. J. Cell. Phys. 163:1995;266-276.
48. Reaves B.J., Bright N.A., Mullock B.M., Luzio J.P. The effect of wortmannin on the localisation of lysosomal type I intergral membrane glycoproteins suggests a role for phosphoinositide 3-kinase activity in regulating membrane traffic late in the endocytic pathway. J. Cell Science. 109:1996;749-762.
49. Rigby W.F.C., Noelle R.J., Krause K., Fanger M.W. The effects of 1,25-dihydroxyvitamin D3 on human T-lymphocyte activation and proliferation: a cell cycle analysis. J. Immunol. 135:1985;2279-2286.
50. Sabath D.E., Monos D.S., Lee S.C., Deutsch C., Prystowsky M.B. Cloned T-cell proliferation and synthesis of specific proteins are inhibited by quinine. Proc. Natl. Acad. Sci. USA. 83:1986;4739-4743.
51. Sabers C.J., Martin M.M., Brunn G.J., Williams J.M., Dumont F.J., Wiederrecht G., Abraham R.T. Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells. J. Biol. Chem. 270:1995;815-822.
52. Schreiber S.L. Chemistry and biology of the immunophilins and their immunosuppressive ligands. Science. 251:1991;283-287.
53. Valverde A.M., Lorenzo M., Navarro P., Benito M. Phosphatidylinositol 3-kinase is a requirement for insulin-like growth factor I-induced differentiation, but not for mitogenesis, in fetal brown adipocytes. Molecular Endocrinology. 11:1998;595-607.
54. S6 kinase. Mol. Cell. Biol. 15:1995;2333-2340.
55. Yu-Lee L.Y. Prolactin stimulates transcription of growth-related genes in Nb2 T lymphoma cells. Molec. and Cell. Endo. 68:1990;21-28.
56. Yu-Lee L.Y., Hrachovy J.A., Stevens A.M., Schwarz L.A. Interferon-regulatory factor 1 is an immediate-early gene under transcriptional regulation by prolactin in Nb2 T cells. Molec. and Cell. Endo. 10:1990;3087-3094.
57. Yu-Lee L.Y., Stevens A.M., Hrachovy J.A., Schwarz L.A. Prolactin-mediated regulation of gene transcription in lymphocytes. Annals New York Academy of Sciences. 348:1990;146-155.